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      • KCI등재
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        Chinese hamster ovary 세포염색체의 G - banding patterns 과 세포주기별 감수성에 미치는 알킬화제의 영향

        이병주,박상대 한국유전학회 1984 Genes & Genomics Vol.6 No.2

        Frequency and site of chromosome aberrations induced by alky-lating agents in Chinese hamster ovary (CHO) cells were determined by G-banding patterns. Only 7 chromosomes retained normal karyotypes. Other chromosomes had either major or minor deletions and/or exchanges. Major type of chromosome aberrations were chromatid type deletions and exchanges, in which deletions were decreased but exchanges were increased as time elapsed. Most of aberrations were observed at R-band or at centromeric regions, indicating non-random distribution of chromosomes. EMS-induced chromosome averrations appeared to be sensitive to S-stage cells.

      • KCI등재

        Multidirectional Pointing Input Using a Hardware Keyboard

        이병주,박해선,방현우 한국전자통신연구원 2013 ETRI Journal Vol.35 No.6

        Herein, we propose a novel method to create multidirectional and multilevel pointing input using only a hardware keyboard. The relative position vectors among pressed keys are calculated into an input vector. The pointing performance of this method is evaluated based on the ISO 9241-9 recommendations. We find that the performance of the method is sufficient to create moderate pointing input, as the measurement of the throughput is close to that of a touchpad, as measured in past studies also using the ISO 9241-9 recommendations.

      • KCI등재
      • KCI등재

        퍼스의 기호학과 라클라우·지젝의 담론이론을 통해서 본 툴민의 논증 이론

        이병주 한국소통학회 2003 한국소통학보 Vol.2 No.-

        이글의 목적은 툴민의 논증이론을 현대의 기호학과 담론이론의 관점에서 재독해하는 것이다. 이 글은 다음의 두 가지 질문을 던지고 있다. 만약, 논증분석의 목적과 기호의 의미화 과정의 분석이 유사한 것이고, 그 둘의 구조가 유사한 것이라면 이러한 유사성은 어떤 이론적 함의를 지니고 있는가? 둘째,논증이 항상 사회적 맥락에 위치지워져야 한다면, 어떤 이론적 수단을 통해 툴민의 논증이론을 철학적-분석적 수준에서 사회학적-정치적 수준으로 확장할 수 있을까? 그러나 이 글의 목적은 이 질문에 대한 완전한 대답을 위한 것이라기보다는 예비적인 대답을 위한 것이며,몇 개의 가정적인 개념들과 가정들을 제시하기 위한 것이다. 이를 위해 다음의 세 가지 우회를 통해 툴민의 이론을 재독해하였다. 첫째로,논증과정과 기호 해석과정간의 구조적 유사성의 이론적 확인을 통해 툴민의 논증이론이 언어학적 전회의 맥락에서 재독해되어야 한다는 사실을 제시하였다. 여기에서 퍼스의 기호해석 모델인 가추법과 논증의 구조 간의 유사성을 확인할 수 있었다.둘째로,논증과정의 한계와 기호해석의 한계는 상징계의 불완전성으로부터 나오며, 논증의 경우 궁극적인 논거 또는 논거의 논거가 이러한 한계를 보안하는 논리를 밝혀 보았다.셋째로,이러한 한계가 사회적 수준으로 연결되는 순간 논증이 헤게모니 기능을 발휘하게 되는 논리를 밝혀 보았다. 이러한 헤게모니 기능을보다정확한 이론적 맥락에서 파악하기 위해서 라클라우와지젝의 담론이론과 헤게모니 이론을 살펴보았으며, 툴민의 논증이론이 라클라우나 지젝의 담론이론에 비추어 어떻게 재독해되어야 할지를 제시하였다. 그리고 이와 같은 논의를 바탕으로 결론 부분에서 더 진행되어야 할 이후의 이론적 작업을 제안하였다. The purpose of this paper is to re-read the argument theory of Toulmin from the viewpoint of contemporary semiotics and discourse theory. This re-read is motivated by two questions. Firstly, if the purpose of analysis of argument is similar that of semiotics-that is to say, the former is a process of argumentation, the later is a process of signification, or the former is a implicated warrant in argument, the later is implicated a code in signification-what is the theoretical implication of this similarity? Secondly, if any argument is always situated in social context and only if we analyze argument in practical situation we can understand exact process and effect of argument, how can we expand Toulmin’s theory from the philosophical-analytical level to the sociological-political level and through what theory can we achieve this expansion? This paper is only preliminary paper, so can not provide for a perfect answer. Instead, this paper can only outline theoretical territory from which further study can find more elaborated theoretical explanation and analytical tool. But, this paper suggests a few tentative concepts and assumptions. Firstly, the homogeneity between the process of argumentation and the process of interpretation of sign-that is to say, abduction-tell us that Toulmin’s theory must be re-understood in term of the linguistic turn. Secondly, through this homogeneity we can see similar structural limits of the argument and the sign-interpretation and both limits are result from the incompleteness of the symbolic. Those limits produce a master signifier and a warrant-of-warrant(in other word, ultimate warrant). The master signifier and ultimate warrant function at the same time to embody impossibility of the perfect totality and to suture this impossibility. Here, we can understand irrational core of rational process of argumentation. But, this irrational core must be understood rational ground of radical democratic project, in other word hegemony strategy, because this incompleteness of totality in Lacanian term, not-all) designate there is no positive guarantee of totality such as perfect society, perfect identity. This impossibility open the empty space from which different social agents create new meaning about their society and possibility of better society through alliance between different social classes. This process of creation is named hegemony by Gramsci. When he tells us that hegemony operates by means of ‘moral persuasion and agreement’, we can understand how relevant we re-think hegemony through Toulmin’s argument theory articulated contemporary discourse theory such as Laclau, Zizek, and Foucault. It is also method by which we can re-think Toulmin’s theory. This is a final suggestion of this paper.

      • KCI등재

        Korean Exchange Rate Regime Change and Its Impact on Inflation in Comparison to Japan and Australia

        이병주 한국개발연구원 2006 KDI Journal of Economic Policy (KDI JEP) Vol.28 No.1

        본 논문은 한국의 근본적인 거시경제변수가 두 가지 다른 환율제도(자유변동 환율제도와 시장평균 환율제도)하에서 어떻게 다르게 반응하는가를 분석ᆞ연구한다. 이와 아울러 같은 기간 동안의 일본과 호주의 거시경제구조에 대한 비교 분석도 곁들인다. 한국은 1997년의 경제위기를 전후하여 환율정책을 시장평균 환율제도에서 자유변동 환율제도로 전환하였다. 이 시점을 계기로 한 한국의 외환정책 변경은 두 가지 환율제도를 비교 분석하는 데 아주 좋은 기회를 제공한다. 화폐경제이론에 기초한 환율결정 모델을 사용하여 대미환율과 거시경제 변수에 대한 관계를 분석해 본 결과, 대미 환율은 시장평균 환율제도하에서보다 자유변동 환율제도하에서 근본적인 거시경제변수에 더 민감하게 반응하는 것으로 나타났다. Impulse Response Analysis 분석결과에 의하면, 환율변동이 물가상승률에 미치는 영향은 시장평균 환율제도하에서보다 자유변동 환율제도하에서 단기적으로 더 큰 것으로 나타났다. 이러한 결론은 개발도상국가에서는 안정적인 관리 환율제도가 경제성장을 위해 필요하다는 일반적인 견해와 일치하는 것이다. This paper examines the macroeconomic structural differences of the free floating exchange rate regime and the managed float exchange rate regime focusing on the Korean economy, and compares it to the two benchmark economies, Japan and Australia. Korea’s shift to the free floating exchange rate regime from the managed float exchange rate regime came after the 1997 economic crisis. Korea’s exchange rate policy provides a unique opportunity to study the different behaviors or roles, if any, of managed float and free floating exchange rate regimes. Based on a simple monetary model, we find that the exchange rates of Korea are more sensitive to the economic fundamentals under the free floating regime than under the managed float regime. Impulse response analysis shows that exchange rate pass-through into domestic variables, especially inflation rate, has a bigger short-term impact under the floating regime than under the managed regime. This finding is consistent with the view that the managed (or fixed) regime provides the domestic price stability necessary for the economic growth for the developing countries.

      • KCI등재

        Quality of Life and Physical Ability Changes After Hospital-Based Cardiac Rehabilitation in Patients With Myocardial Infarction

        이병주,고진영,김애령,전성민,박민혁,양동훈,박헌식,정태두 대한재활의학회 2017 Annals of Rehabilitation Medicine Vol.41 No.1

        Objective To evaluate the effect of hospital-based cardiac rehabilitation (CR) on quality of life (QOL) and physical ability in patients with myocardial infarction (MI).Methods Patients with MI who were referred to the Cardiac Health and Rehabilitation Center 2 weeks after percutaneous coronary intervention were divided into CR and non-CR groups. The CR group performed supervised exercises 3 times a week for 2 months. QOL assessment, using the 36-item Short-Form Health Survey (SF-36) and physical ability evaluation were performed at the beginning and end of CR.Results The CR group demonstrated statistically significant improvements in physical functioning (PF), physical role functioning (RP), bodily pain (BP), general health perceptions (GH), vitality (VT), social role functioning (SF), emotional role functioning (RE), mental health (MH), physical component summary (PCS), and mental component summary (MCS). The non-CR group showed improvement in RP. Secondary outcomes, including resting heart rate (RHR), maximal oxygen consumption (VO2max), metabolic equivalent of task (MET), maximal exercise time (ETmax), stage 3 Borg rating of perceived exertion (3RPE), maximal Borg rating of perceived exertion (RPEmax), and stage 3 rate pressure product (3RPP), improved in the CR group. The non-CR group showed improvements in VO2max, MET, ETmax, and 3RPE. There were significant differences in improvements in PF, RP, BP, VT, SF, MH, MCS, RHR, VO2max, MET, ETmax, 3RPE, and 3RPP between the two groups.Conclusion Male patients with MI demonstrated improvements in QOL and physical ability following hospital-based CR; the impact on the mental component was greater than that on the physical component.

      • KCI등재

        교배형 분자마커를 이용한 신품종 밀리타리스 동충하초 ‘도원홍초 2호’의 품종 특성

        이병주,이미애,김용균,이순계,최영상,이병의 한국버섯학회 2017 한국버섯학회지 Vol.15 No.3

        The mushroom species Cordyceps militaris has been studied and cultivated as a medicinal mushroom due to its multiple valuable biological and pharmaceutical activities. For breeding new strains of C. militaris, multiplex PCR assays were performed using primers specific for its mating type genes, MAT1-1 and MAT1-2. Mating types and mating status were confirmed, as evidenced by DNA bands at 233-bp and 191-bp for MAT1-1 and MAT1-2 respectively. The novel 'Dowonhongcho 2ho’ was developed through mating; they were found to possess high-quality fruiting bodies when grown in artificial media. The stromata of the new strain were club-shaped, with a bright orange-red color, and measured 7.1 cm in length. They had an average cordycepin content of 0.33%. Compared to 'Dowonhongcho,' the new strain had a 7% higher yield, as well as firm fruiting bodies. The optimum temperature for mycelial growth was 20~25°C, and the optimum temperature for stroma development was 18~22 °C. The fruiting bodies developed after 49.1 days from inoculation. The use of mating type molecular markers improved the breeding efficiency of the new strain 'Dowonhongcho 2ho.’ Thus, they may be valuable for artificial cultivation and industrial-scale production of C. militaris with excellent characteristics.

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