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      • KCI등재

        심부전증 환자에서 Valsartan과 Ramipril의 임상적 효과 비교

        이기홍,정명호,안영근,이우석,정대호,조정관,박종춘,강정채,오석규,김남호,윤경호,유남진,문용,류제영,임지현,전성희,박옥영,이승욱,강동구 대한심장학회 2008 Korean Circulation Journal Vol.38 No.2

        Background and Objectives: Angiotensin II receptor blocker (ARB) has emerged as an alternative to angiotensin converting enzyme inhibitor (ACEI) for the treatment of heart failure. This study aimed at comparing the effectiveness and safety of valsartan with ramipril in patients with heart failure, and these patients were hospitalized at Chonnam National University Hospital, Wonkwang University Hospital, Gunsan Medical Center, Presbyterian Medical Center, Seonam University Hospital and Gwangju Christian Hospital. Subjects and Methods: Between March 2005 and March 2007, 82 patients (60.5±12.4 years, 59 males) who complained of class II to IV dyspnea, according to the New York Heart Association (NYHA) classification, and who had low left ventricular ejection fraction (LVEF) less than 50% were randomly allocated to valsartan or ramipril. After 6 months, the clinical symptoms, vital signs, biochemical tests and echocardiography were compared between the two groups. Results: The NYHA class was improved in both groups (the valsartan group: 2.31±0.51 vs. 1.46±0.58, p<0.001; the ramipril group: 2.21±0.55 vs. 1.61±0.50, p<0.001). The incidence of cough, as measured by the cough index, was significantly lower in the valsartan group than in the ramipril group (p=0.045). The LVEF was improved in both groups (the valsartan group: 36.4±8.5% vs. 46.9±12.9%, p<0.001; the ramipril group: 35.1±8.5% vs. 45.3±11.2%, p<0.001). The improvements of the left ventricular end-systolic dimension (p=0.754) and end-diastolic dimension (p=0.998) were not different between the two groups. N-terminal Pro-B-type natriuretic peptide level was improved in both groups (the valsartan group: 2619.6±4213.5 vs. 995.4±2186.0 pg/mL, p=0.012; the ramipril group: 3267.9±4320.0 vs. 828.1±1232.8 pg/mL, p=0.009), and there was no difference between the groups (p= 0.877). Conclusion: Both valsartan and ramipril were effective treatments, with relatively low adverse events, in patients with heart failure. Background and Objectives: Angiotensin II receptor blocker (ARB) has emerged as an alternative to angiotensin converting enzyme inhibitor (ACEI) for the treatment of heart failure. This study aimed at comparing the effectiveness and safety of valsartan with ramipril in patients with heart failure, and these patients were hospitalized at Chonnam National University Hospital, Wonkwang University Hospital, Gunsan Medical Center, Presbyterian Medical Center, Seonam University Hospital and Gwangju Christian Hospital. Subjects and Methods: Between March 2005 and March 2007, 82 patients (60.5±12.4 years, 59 males) who complained of class II to IV dyspnea, according to the New York Heart Association (NYHA) classification, and who had low left ventricular ejection fraction (LVEF) less than 50% were randomly allocated to valsartan or ramipril. After 6 months, the clinical symptoms, vital signs, biochemical tests and echocardiography were compared between the two groups. Results: The NYHA class was improved in both groups (the valsartan group: 2.31±0.51 vs. 1.46±0.58, p<0.001; the ramipril group: 2.21±0.55 vs. 1.61±0.50, p<0.001). The incidence of cough, as measured by the cough index, was significantly lower in the valsartan group than in the ramipril group (p=0.045). The LVEF was improved in both groups (the valsartan group: 36.4±8.5% vs. 46.9±12.9%, p<0.001; the ramipril group: 35.1±8.5% vs. 45.3±11.2%, p<0.001). The improvements of the left ventricular end-systolic dimension (p=0.754) and end-diastolic dimension (p=0.998) were not different between the two groups. N-terminal Pro-B-type natriuretic peptide level was improved in both groups (the valsartan group: 2619.6±4213.5 vs. 995.4±2186.0 pg/mL, p=0.012; the ramipril group: 3267.9±4320.0 vs. 828.1±1232.8 pg/mL, p=0.009), and there was no difference between the groups (p= 0.877). Conclusion: Both valsartan and ramipril were effective treatments, with relatively low adverse events, in patients with heart failure.

      • KCI등재

        아파트의 동력변압기 용량 최적화 연구

        이기홍,성세진 한국조명전기설비학회 2001 조명·전기설비학회논문지 Vol.15 No.1

        본 연구에서는 아파트에 시설되어 있는 동력설비들의 운전실태를 측정하고 분석하여 동력변압기 최적용량산출을 위한 동력부하의 종합수용률을 제시하였다. 측정결과 설비별 수용률은 급수동력부하는 47[%]로 분석되었으며 변압기를 효율적으로 운전하기 위해서는 동력부하의 종합 수용률을 현재의 52[%]에서 42[%]로 변경하는것이 적절한 것으로 분석되었다. To establish the optimized capacity of power transformer, this paper proposed the total demand factor of power supply facility. For this purpose, it was measured and analysed the operating pattern of power supply acility Installed in the apartment. As a result, it is found that the demand factor of each facility is following that : i) In case of [Xlwer water suwly facility ; 47[%], ii) In case of waste water facility ; 44[%]. Also, it was analysed that the optimized total demand factor of power load is proper 42[%1 than 52[%] to lead the efficiency operation.ration.

      • KCI등재후보

        시합기 복합훈련프로그램이 남자 국가대표 알파인 스키 선수들의 무릎관절 근력에 미치는 영향

        이기홍,김정우,전용균,제갈윤석 한국웰니스학회 2014 한국웰니스학회지 Vol.9 No.2

        이 연구는 남자 국가대표 알파인 스키선수들을 대상으로 시합기 복합훈련프로그램 적용 전·후의 무릎관절근력을 비교?분석하 여 선수들의 체력발달 변화를 규명하는 연구이다. 이 연구의 대상은 국가대표 남자 알파인 스키선수들(랭킹 10위 이내)로서 현재 대한스키협회에 등록되어 경기에 출전하는 남자선수 8명으로 선정하였다. 무릎관절 근기능을 알아보기 위해 등속성 근기능 측정 기기인 Cybex HUMAC NORM을 이용하였다. 훈련프로그램에 따른 무릎관절 등속성 근기능의 차이를 검증하기 위해 paired t-test 을 실시하였고, 모든 통계분석을 위한 유의수준은 a= .05로 설정하였다. 각 측정변인의 측정결과는 다음과 같은 결과를 얻었다. 첫 째, 무릎관절의 최대근력과 상대 최대근력은 훈련 후가 크게 나타났으며 최대 신근력과 상대 최대 신근력이 통계적으로 유의한 차이를 보였다(p<.05). 둘째, 무릎관절의 평균파워에서는 신근력에서 통계적으로 유의한 차이를 보였다(p<.01)(p<.05). 셋째, 무릎관 절의 총일량 검사에서 통계적으로 유의한 차이를 보였다(p<.05) 이러한 결과들을 종합 할 때 남자 국가대표 알파인 스키선수들의 훈련 전·후 측정 시에 무릎관절의 근력은 훈련 후가 통계적으로 좋은 것을 알 수 있었다. 이는 알파인 스키선수들의 경기력향상 을 위해서는 훈련 초반부터 후반까지 선수들의 체력을 유지, 발달시키는 것이 무엇보다 우선 시 되기 위한 지속적인 체력트레이 닝이 필요함을 시사한다. The purpose of this study is to compare and analyze the changes in the isokinetic muscular function of knee joint of male national alpine skiers before and after the complex training program in season. and to identify the characteristics of the athletes' physical development. The subjects of this study are 8 national male alpine skiers who are registered with Korean Ski Association, within ranking 10 and participating in the game. Isokinetic knee joint muscular strength employed Cybex HUMAC NORM. in order to verify the difference of measurement of knee-joint isokinetics according to the training program, paired t-test was performed and the level of significance for all the statistic analysis was set for a= .05. According to results, the following conclusions were obtained. 1. The maximum muscular strength and maximum muscular strength per body weight of the knee joint shows greater measurements after a season and maximum extensor muscular strength and %BW maximum extensor muscular strength showed noticeable difference. (p<.05). 2. The average power of the extensor muscular strength of the knee joint in a statistically significant difference(p<.01)(p<.05). 3. When the rate of total work of the knee joints were measured, there has a statistically noticeable difference(p<05). When the muscular strength in the knee joints of the male national alpine skiers were measured before and after the complex training program, our conclusion is that they showed statistically better results after the training. This means that in order to improve the performance level of the skiers, it should be a priority to maintain and develop the level of the physical strength at the beginning of the season until the end of the season.

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