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      • SCOPUSKCI등재

        성상신경절 차단후 발생한 경부혈종

        은현희(Hyun Hee Eun),황호용(Ho Yong Hwang),류홍현( 대한통증학회 1997 The Korean Journal of Pain Vol.10 No.1

        Stellate ganglion block is the most widely practiced procedure in the pain clinics due to its wide range of indications. We experienced a rare case who exhibited severe hematorna in neck following stellate ganglion block. A 58-year-old female patient injured by a traffic accident was admitted to the department of neuro- surgery for the treatment of cerebral contusion, cervical and lumbar sprain and left arm paresis. Because left sensory neural hearing loss occurred, the patient was referred to the pain clinic for treatment with stellate ganglion block due to her left sensory neural hearing loss. The next day stellate ganglion block was done with a negative aspiration for blood. Three hours later, hematoma in neck was found and the patient complained of pain in the neck and dyspnea. The symptoms and signs of respiratory difficulty were progressively aggravated. The hematoma was removed and ruptured muscular branch of vertebral artery was ligated under surgical exploration. In this case, the needle was apparently in the branch of vertebral artery during or after injection in spite of the negative aspiration for blood. Authors recommend that compression of the injected site over 5 minutes should be necessary to prevent a hematoma formation despite of a negative aspiration for blood

      • 剔出 家兎 腸片에서 5-Hydroxytryptamine 筋收縮效果에 對한 硏究

        황호용,한규송,곽용근,조규박 의과학연구소 1988 全北醫大論文集 Vol.12 No.4

        To investigate the mechanism of contractile action of 5-hydroxytryptamine(5-HT) on the isolated intestinal smooth muscle preparation of rabbit, the influence of cyproheptadine, atropine, hexamethonium, morphine and hemicholinium treatment on the action of 5-HT were studied in this experiment. Results obtained from this experiment were summerized as follows : 1. 5-HT caused contractile response of isolated intestinal smooth muscle in dose-dependent manner. 2. In the intestinal preparation of saline treated rabbit, contractile action of 5-HT was inhibited by cyproheptadine, atropine or morphine, but not influenced by hexamehonium. 3. In the hemicholinium-pretreated preparations, the contractile response of intestinal smooth muscle was significantly inhibited by cyproheptadine, but did not inhibited by atropine or morphine. And also, hexamethonium did not influenced on the action of 5-HT as in the preparation of saline-treated rabbit. These results suggest that there are two mechanisms responsible for contractile action of 5-HT in the isolated rabbit intestinal smooth muscle preparation. One is the 5-HT receptor on the smooth muscle(possibly D receptor), and the other is the receptor on the parasympathetic ganglia which different from the hexamethonium-sensitive sites. 가토 회장 평활근 표본에서 5-hydroxytryptamine의 약리작용에 대한 지견을 얻고자 정상 및 hemicholi-nium 처리 가토의 회장편에서 5-hydroxytryptamine의 수축효과에 대한 cyproheptadine, atropine, hexame-thonium 및 morphine의 영향을 관찰하여 다음과 같은 결과를 얻었다. 1. 수조내 5hydroxytryptamine은 가토 회장 평활 근편을 용량에 비례하여 수축시켰다. 2. 정상 가토의 회장편에서 5-hydroxytryptamine의 평활근의 수축작용은 cyproheptadine, atropine 및 morphine에 의해 감약되었으며, hexamethonium에 의해서는 영향받지 않았다. 3. hemicholinium 처리 가토의 회장편에서 5-hydroxytryptamine의 평활근편 수축작용은 cyproheptadine에 의해 현저히 억제되었으며 atropine, hexamethonium 그리고 morphine에 의해서는 영향받지 않았다. 이상의 실험성적은 적출 가토 회장 평활근에 있어서 5-hydroxytryptamine의 근편수축작용은 평활근에 있는 5-HT 수용체와 말초 부교감신경에 연계된 신경절에 존재하는 수용체 두가지의 작용점에 공히 작용하여 초래되며 이 신경절은 hexamethonium 민감부위와는 다른 것으로 사료된다.

      • SCOPUSKCI등재

        인공고관절 치환술시 유도저혈압에 사용된 Nitroprusside 와 Esmolol 의 효과

        이용우,황호용,백승완,은현희,류홍현 대한마취과학회 1997 Korean Journal of Anesthesiology Vol.33 No.2

        Background : Esmolol is a short acting sympathetic beta receptor antagonist, and it was successfully applied to induced hypotension. Esmolol lowers blood pressure by decreasing cardiac output, and does not cause vasodilation. This property of esmolol may help to decrease bleeding during induced hypotension. In this study, we tried to elucidate the effect of esmolol on induced hypotension for total hip arthroplasty. Method : Twenty patients receiving total hip arthroplasty were randomly divided to two groups. Esmolol group(10 patients) received esmolol as a hypotensive agent, and sodium nitroprusside(SNP) group(10 patients) received SNP as a hypotensive agent. We measured arterial blood gas analysis, vital sign, amounts of bleeding, amounts of transfusion and administered fluid, and various laboratory findings. Results : Induced hypotension was successfully performed in either esmolol and SNP group. Heart rate increased by SNP, and decreased by esmolol. There were no statistically significant differences between the two groups in amounts of bleeding, amounts of transfusion or administered fluid, and laboratory findings. Arterial oxygen tension was relatively constant in esmolol group, but decreased in SNP group. Conclusion : Esmolol can be used as a single hypotensive agent during induced hypotension without significant side effects during total hip arthroplasty. (Korean J Anesthesiol 1997; 33: 324∼329)

      • SCOPUSKCI등재

        복강경하 담낭절제술시 복강내 투여한 국소마취제의 술후 진통효과

        이용우,박한석,황호용,이수일,황기백 대한마취과학회 1998 Korean Journal of Anesthesiology Vol.34 No.2

        Background : Although pain after cholecystectomy was reduced significantly since the advent of laparoscopic surgery, many patients still complain of moderate pain after the surgery. Recently intraperitoneal instillation of local anesthetics is known as safe, simple, and effective method of treatment for pain after laparoscopic cholecystectomy Methods : Three groups are randomized; group I (normal saline 80 ml), group II (0.5% lidocaine 80 ml 1:400,000 epinephrine) and group III (0.125% bupivacaine 80 ml 1:400,000 epinephrine). Local anesthetics are instilled via subdiaphragmatic trocar hole just after creation of carboperitoneum. Visual analogue scale(VAS), total used analgesics amount, time to first analgesics request, time to out of first flatus and complications are compared. Lidocaine blood concentrations are checked in five cases of the patients after lidocaine instillation. Results: The VAS was insignificant among groups except 3 hr, 6 hr postoperatively. Time to first analgesics request are prolonged in lidocaine and bupivacaine group. Used analgesics amount are significantly less in lidocaine group than control group. Time to out of first flatus was significantly shorter in bupivacaine group. No significant complications were noted. The blood concentration of lidocaine were variable and the highest concentration in five of one case was 1.8 g/ml. Conclusions : Although intraperitoneal instillation of local anesthetics is simple, safe method for controlling pain after laparoscopic cholecystectomy, it is not so much effective because of dilution with irrigating saline and suctioning intraoperatively and postoperative scavenging by evacuator. (Korean J Anesthesiol 1998; 34: 413∼417)

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