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홍성우,오승원,이철민,권혁태,Jung Hyeon Hyeon,Jong Seop Gwak 대한의학회 2014 Journal of Korean medical science Vol.29 No.11
Nutrition labels are helpful for chronic disease management in patients requiring balancednutritional intake. This study aimed to investigate the association between the use ofnutrition labels and chronic diseases (hypertension, diabetes mellitus, and hyperlipidemia)by using the 2008-2009 Korea National Health and Nutrition Examination Survey data. Atotal of 10,695 individuals aged 20 and over was included in the analysis. Using multiplelogistic regressions, there was no difference in nutrition label use between the chronicdisease and normal groups (men with hypertension OR, 0.97; 95% CI, 0.75-1.27; womenwith hypertension OR, 0.83; 95% CI, 0.67-1.03; men with diabetes OR, 0.70; 95% CI,0.45-1.08; women with diabetes OR, 1.13; 95% CI, 0.84-1.53; men with hyperlipidemiaOR, 0.85; 95% CI, 0.59-1.23; women with hyperlipidemia OR, 1.14; 95% CI, 0.91-1.44). In hyperlipidemia patients, awareness (OR, 1.55; 95% CI, 1.03-2.35) and control (OR,2.19; 95% CI, 2.32-3.63) of disease were related to nutrition label use; however, nosignificant associations were found for the hypertension and diabetes mellitus patients. Considering the importance of dietary habits in the management of chronic diseases, animprovement in nutrition label use by patients with these diseases is required.
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Matrix Metalloproteinase-2 and -7 Expression in Colorectal Cancer
홍성우,강윤경,이병모,이우용,장여구,백인욱,이혁상 대한대장항문학회 2011 Annals of Coloproctolgy Vol.27 No.3
Purpose: Matrix metalloproteinase-2 (MMP-2) and MMP-7 have been implicated in tumor growth and metastasis. This study aimed to investigate the expressions of MMP-2 and -7 in colorectal cancer and to evaluate their values as prognostic markers. Methods: Immunohistochemical staining for MMP-2 and -7 was done in 144 resected colorectal cancer specimens. Clinicopathological data and survival results were compared with regard to the expression results. Results: The expression rates of MMP-2 in tumor cells in the tumor center and the tumor border were 16.7% and 38.9%,respectively. That of MMP-2 in stromal cells was 27.8%. MMP-7 immunoreactivities of tumor cells in the tumor center and the tumor border were 6.9% and 23.6%. The expressions of MMP-2 and MMP-7 were correlated. MMP-2 expression in stromal cells was more increased in the distal part of the colorectum: 8.8% in right colon cancer, 29.5% in left colon cancer and 36.4% in rectal cancer. MMP-2 expression of tumor cells in the tumor border was correlated with T-stage. MMP-7 expression of tumor cells in the tumor border was increased in case of infiltrative cancer compared with fungating tumor. The expression patterns of MMP-2 and -7 were not correlated with other clinicopathological factors, including tumor markers,node metastasis, distant metastasis, lymphatic invasion, tumor differentiation, and recurrence. No significant associations between the overall and disease-free survival rates and the MMP-2 and -7 expression patterns were noted. Conclusion: The high expression rates of MMP-2 and -7 in tumor borders suggest that MMP-2 and -7 have some role in tumor invasion, but in this study, MMP-2 and -7 did not appear to be significant predictors of prognosis in colorectal cancer.
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실시간 멀티미디아 스트리밍을 위한 계층 통합 패킷 스케줄링 기법
홍성우,원유집 한국통신학회 2009 韓國通信學會論文誌 Vol.25 No.5
본 연구의 목적은 패킷 스케줄링을 통하여 사용자가 느끼는 QoS 를 극대화함에 있다. 이를 위해 제안하는 중요성 기반 패킷 스케줄링 기법은 패킷 스케줄링의 두 가지 근본적인 문제를 해결한다. 하나는 “무엇을 보내는가” 이고 다른 하나는 “언제 보내는가“ 이다. 대역폭에 적응하기 위해 모든 패킷을 보낼 수 없을 경우에는 일부의 패킷을 선택해서 보낼 수밖에 없다. 이를 위해 효과적으로 프레임 상관관계를 파악하고 프레임의 중요도를 정량화하는 패킷 Significance 개념을 제안한다. Greedy 기법이 패킷 선택 문제에 사용되었고, 패킷 Significance 를 고려하여 간격이 할당되었다. 널리 공개된 MPEG-4 비디오 클립이 실험에 사용되었으며, 네트워크 시뮬레이션 (network simulator version 2)에 디코딩 엔진이 삽입되었고, 성능 평가를 위해 PSNR을 측정하였다. 크기 기반 및 비트 레이트 기반 최선 패킷 스케줄링 기법과 성능을 비교 분석하였다. 본 연구에서 제안하는 중요성 기반 패킷 스케줄링 기법이 성공적으로 더 중요한 패킷에 차별화 된 보호 기법을 적용하였으며, QoS를 크게 향상시키는 것을 확인할 수 있었다.
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