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한성필,조용순,윤석규,김형섭,배균섭 대한임상약리학회 2017 Translational and Clinical Pharmacology Vol.25 No.3
Caffeine is a naturally-occurring central nervous system stimulant found in plant constituents includingcoffee, cocoa beans, and tea leaves. Consumption of caffeine through imbibing caffeinateddrinks is rapidly growing among children, adolescents, and young adults, who tend to be morecaffeine-sensitive than the rest of the general public; consequently, caffeine-related toxicities amongthese groups are also growing in number. However, a quantitative and interactive tool for predictingthe plasma caffeine concentration that may lead to caffeine intoxication has yet to be developed. Using the previously established population-pharmacokinetic model, we developed “caffsim” Rpackage and its web-based applications using Shiny and EDISON (EDucation-research Integrationthrough Simulation On the Net). The primary aim of the software is to easily predict and calculateplasma caffeine concentration and pharmacokinetic parameters and visualize their changes aftersingle or multiple ingestions of caffeine. The caffsim R package helps understand how plasma caffeineconcentration changes over time and how long toxic concentration of caffeine can last incaffeine-sensitive groups. It may also help clinical evaluation of relationship between caffeine intakeand toxicities when suspicious acute symptoms occur.
작은보가 미시공된 철근콘크리트 구조물의 열화 성상에 관한 연구
한성필 ( Han Seong-pil ),안형준 ( Ahn Hyung-joon ) 한국구조물진단유지관리공학회 1997 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.1 No.1
The objective of this study is to investigate the R.C structure is omited beam. In the investigation items, there are the crack, the deflection, the size of member, the location of reinforcement etc. The struture in this study was carried out to observe the defect.
한성필(S.-P. Han),박태균(T.-K. Park),김내현(N.-H. Kim) 대한기계학회 2005 대한기계학회 춘추학술대회 Vol.2005 No.5
Thermal performance analysis was conducted for the cross-flow enthalpy heat exchanger. Appropriate heat transfer coefficient and friction factor equations for laminar channel flow were selected, and the heat exchanger was analyzed using the unmixed cross-flow ε-NTU relationship. It is shown that the simple approach reasonably predict the available heat transfer and the pressure drop data. Additional issues on the entrance length, fin efficiency, mass transfer through the membrane paper are discussed.
한성필(Sung-Phil Han),박태균(Tae-Gyoon Park),김내현(Nae-Hyun Kim),박형채(Hyung-Chae Park) 대한설비공학회 2006 대한설비공학회 학술발표대회논문집 Vol.2006 No.11
Performance of the CO₂ slush maker operating with R-404A was experimentally investigated. The slush maker had three evaporator, and test was conducted at standard outdoor condition (32℃, 65 RH). The optimum refrigerant charge was obtained to be 400g. The time required for slush making was 53 minutes and the power consumption was 1.33 ㎾. The effect of the number of operating evaporators was also investigated. The slush making time and the power consumption increased as the number of operating evaporators increased.