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김진복(Jin Pok Kim),송인성(In Sung Song),최규완(Kyoo Wan Choi),최병인(Byung Ihn Choi),박재갑(Jae Gahb Park),김용일(Yong Il Kim),정현채(Hyun Chae Jung),최국진(Kuk Jin Choe),서정민(Jeong Meen Seo),한상욱(Sang Uok Han),이기형(Kee Hyung 대한소화기학회 1993 대한소화기학회지 Vol.25 No.5
N/A Hereditary nonpolyposis colorectal cancer (HNPCC) is characterized by the development of colorectal cancer at an early age, a preponderance of tumors in the proximal colon and an excess of synchronous and metachronous colorectal cancer. When HNPCC is confirmed, a subtotal colectomy is indicated at the time of initial colon cancer treatment. To study the current status of Korean HNPCC patients and the appropriate treatment for the Korean HNPCC patients, we investigated the 10 HNPCC families registered in Korean Hereditary Colorectal Cancer Registry. Ten HNPCC families included 41 (31 males and 10 females) colorectal cancer patients. Operative and pathologic records are available from 25 HNPCC patients. Twenty five patients received 30 operations: 8 cases of right hernicolectomy, 8 cases of left hemicolectmoy, 4 cases of anterior resection, 5 cases of low anterior resection, 2 cases of abdominoperineal resection, 2 cases of subtotal colectomy and 1 case of total colectomy. Eleven patients (44%) of those 25 HNPCC patients had the synchronous, metachronous colorectal cancer or combined colorectal polyps. Because 10 patients of those eleven patients with cornbined colorectal tumors had the lesions in both side of large bowel, we recommended that the resection of colon for Korean HNPCC patients should be more than subtotal colectomy.