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      • KCI등재후보

        Wilson 씨병 2 예의 Penicillamine 에 의한 치험예

        최하진 ( Ha Chin Choi ) 대한내과학회 1972 대한내과학회지 Vol.15 No.7

        A 14-year old girl with Wilson`s disease and another her 8 year old brother with asymptomatic Wilson`s disease were treated with potassium sulfide, penicillamine and british antilewisite (BAL) for 3 months. Clinically they are excellent, the girl patient`s

      • SCOPUSKCI등재

        간 질환들에 있어서 HBs 항원 및 HBs 항체 공존예에 관한 관찰

        정정명(Jung Myung Chung),최하진(Ha Jin Choi),박경태(Kyung Tae Park),이시억(Si Eok Lee),진지천(Gi Chun Chin),강기상(Ki Sang Kang),설상영(Sang Yung Seol) 대한소화기학회 1988 대한소화기학회지 Vol.20 No.1

        N/A A clinica] analysis was made, by enzyme immunoassay, of 64 cases of coexistence of HBs antigen and HBs anti-body in the same serum with the subtype in 12 cases of them being observed. The results were as follows: 1) The overall incidence of coexistence in one period was 1.9% (64/3,395). 2) The highest occurrence rate of coexistence was found in age group of 5th decade: 14 cases (21.9%); in age group of 6th decade: 17 cases (26.6%); and the ratio of male to female was 2.4:l. 3) The diagnostic distributions were 18 cases of liver cirrhosis, 12 cases of hepatoma, 6 cases of chronic active hepatitis, 6 cases of acute viral hepatitis, 7 cases of healthy carrier, and 15 cases were suspected to be chronic hepatitis not confirmed by liver biopsy. 4) In 64 cases of coexistence we studied Hbe antigen and Hbe anti-body in 32 cases. In this study Hbe antigen positive and Hbe antibody negative was found in 18 cases (56.3%); Hbe antigen negative and Hbe antibody positive in 11 cases (34.4%); both Hbe antigen and Hbe antibody vere positive in 1 case (3.1%) and negative in 2 cases (6.2%). 5) The results of subtype were as follows: in 12 cases of HBs antigen positive only, 8 cases were of ay type and the other 4 cases of ay/ad complex type. And in 12 cases of HBs antibody positive onlv, 5 cases v:ere found to be of anti-y type. 5 cases of anti-d type, 1 case of anti-a type and 1 case of anti-y/anti-d complex type. And in 12 cases of HBs antigen and HBs antibody coexistence, ay type antigen were found in 8 cases, and antibody types of these antigen were 8 cases of anti-y type, and 1 case of anti-y/anti-d complex type. In conclusion, although the results of these studies are those of the screening test and have geographic limitation. The coexistance of HBsAg and anti-HBs is considered mostly as a form of seroconversion and rarely as a result of the superinfection with another subtype.

      • SCOPUSKCI등재

        식도 정맥류의 내시경적 분류에 관한 연구

        정정명(Jung Myung Chung),정해철(Hae Chul Chng),설상영(Sang Yeong Seol),정승진(Seung Jin Jeong),최석렬(Seok Reyol Choi),최하진(Ha Chin Choe) 대한소화기학회 1985 대한소화기학회지 Vol.17 No.1

        N/A Although several classifications of esophageal varices are reported at present monent, none of them seems to be perfect in terms of clinical applicability. Some are too simple to cover the whole features of varices, or too much complicated to apply practically to clinical practices. Recent remarkable advances of endoscopy has let more precise serial observations and prognostic evaluation of varices be possible without great difficulties. Having observed 373 cases of esophageal varices from Jan. 1981 to June. 1984 at Paik Hospital, In-Je Medical College, we have tried a new classification of esophageal varices, according to not only their shape, size, numbers, colors and locations, but having particular consideration on their bleeding episodes. Endoscopic grades of esophageal varices are classified into following 4 grades, Grade I: One or two tiny tortuous, blue colored varices, less than 2 mm in diameter, being localized in lower esophagus. Grade II: Bead-like tortuosity, blue colored varices, mostly 2-4 mm in diameter being localized in lower esophagus. Grade III: Varices on the top of the varices, red colored, mostly more than 4 mm in diameter with spreading up to mid esophagus. Grade IV: Grade III varices with spreading through the entire esophagus and or down to the fundus of stomach. Bleeding tendency was most frequently observed in Grade IV varices.

      • 하대정맥 폐쇄증 1예

        임채준,강영희,정정명,최하진,배철 인제대학교 1983 仁濟醫學 Vol.4 No.1

        좌우측 측복벽과 배부에 부측순환이 현저하게 발달한 하대정맥 폐쇄증 1예를 경험하여 문헌 고찰과 함께 보고하는 바이다. A case of inferior vena cava obstruction with the markedly developed collateral circulations on the both lateral sided of the abdomen and back in a 34 yrs old female is reported. The patient had a history of ingestion of herb medicine and oral contracptive pills intermittently for irregular mensturation and abdominal discomfort on the left lower quadrant for 12 yrs. The angiography revealed complete obstruction of inferior vents cava just below the diaphragm. Through the well developed collateral circulations, no specific treatment wart tried.

      • Budd-Chiari 증후군 만성 C형 간질환이 동반된 환자에서 발생한 간세포암 1예

        김석주,최하진 인제대학교 1999 仁濟醫學 Vol.20 No.2

        The HCV-associated chronic liver disease and the Budd-Chiari syndrome are considered to be one of the predisposing factors of hepatocellular carcinoma. We experienced a case of hepatocellular carcinoma in a 60 year-old female patient, who had suffered from a longstanding Budd-Chiari syndrome and HCV-associated chronic liver disease. Two factors may have influenced synergistically on the hepatocarcinogenesis in this patient. But the exact role of the each factor needs to be further evaluated wish more cases.

      • 바다담치로부터 용혈성을 나타내는 독소의 결정화 및 그 특성

        이인,윤용균,최하진,최미연,정관일 인제대학교 1988 仁濟醫學 Vol.9 No.2

        바다담치의 소화관으로부터 사람의 적혈구에 용혈을 일으키는 성분을 분리하여 그 성질을 검토한 결과 용혈 활성은 pH 4.0 부근에서 9.0 부근까지 대체로 크게 나타났다. 또한 알콜류 중에서 Benzyl alcohol, polyvinyl alcohol 및 n-Propyl alcohol 등이, 금속 화합물 가운데는 Cu2+가 용혈 활성을 상승시켰다. 한편 효소 저해제로서는 0.5mM의 Trichloroacetic acid, NaF 외에도 Pentachlorophenol 및 o-Phenanthroline 등이 상승 효과를 나타내었으나 0.5mm의 2-Mercaptoethanol과 NaCN 등은 다소 저해하는 것으로 보였다. 분리된 용혈 물질은 그 활성이 온도에 의해 변화하지 않았으며 열에 안정성이 큰 물질로 사료되었다. From the digestive glands of sea mussels, a substance showing the hemolytic activity to human red blood cells was isolated and discussed. The results indicated that the positive hemolytic activity was generally maintained at near pH 4.0 to 9.0. The effects of alcohols, metal compunds, or enzyme inhibitors to the isolated substance was examined on the hemolytic activity. The higher hemolytic activity was presented at benzyl alcohol, polyvinyl alcohol and n-propyl alcohol as alcohols, and Cu2+ as metal ions, and 05mM trichloroacetic acid, NaF, pentachlorophenol and o-phenanthroline as enzyme inhibitors. But the inhibition effects to the hemolytic activity were also obtained from 0.5mM of 2-mercaptoethanol and NaCN as enzyme inhibitors. The hemolytic activity to temperatures was not changed and the isolated substance causing hemolysis was considered as a heat-stable one.

      • SCOPUSKCI등재

        심한 저혈당증을 동반한 간세포암 1예 : 인슐린양 성장인자(IGF)와 인슐린양 성장인자 결합 단백질(IGFBP) 포함

        김석주,윤보영,최하진 대한간학회 1999 Clinical and Molecular Hepatology(대한간학회지) Vol.5 No.4

        We report a case of hepatocellular carcinoma presented with severe hypoglycemia. Computerized tomography and ultrasonography revealed a massive bilateral tumor with portal vein thrombosis. The levels of IGF-II (113 ng/mL) and IGFBP-3 (815 ng/mL) measured in the plasma, were lower than normal range. There was strong immunoreactivity of IGF-I and IGF-II in immunohistochemical stain of tumor cells. (Korean J Hepatol 1999;5:332-337)

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