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      • KCI등재

        해결중심 집단미술치료가 여고생의 스트레스 대처방식과 자존감에 미치는 효과

        최윤숙,김갑숙 한국미술치료학회 2009 美術治療硏究 Vol.16 No.4

        This study is to learn the effects of solution-focused group art therapy on highschool girls' stress coping style and self-esteem. Study subjects are divided into the control group of eleven and the experimental group of twelve students, all selected from the first graders of a girls' high school who volunteered to participate in the therapy program. The experimental group received a total of 8 therapy sessions, each lasting 120 minutes. Measuring tools used are both pretest and posttest of measuring the stress coping style, self-esteem and PITR projection, together with an analysis of the score changes on the scaling questions directed to the participants at the second, fifth and eighth sessions. For data analysis, structural equation model is taken for stress coping styles and self-esteem, t-test and qualitative analysis for PITR, one-way random analysis for pretest and posttest scores, and qualitative analysis for the progress of therapy sessions. The results are as follows. First, the experimental group have become to use more of emotion-reducing coping style as well as hopeful-thinking coping style than the control group. Second, in PITR analysis, the experimental group scored higher on stress coping strengths than the control group. Third, posttest scores exhibits more positive effects on scaling questions than pretest scores. Fourth, the experimental group achieved higher self-esteem than the control group. It can be concluded therefore that solution-focused group art therapy is positively effective in enhancing the highschool girls' self-esteem and stress coping styles. 본 연구는 해결중심 집단미술치료가 여고생의 스트레스 대처방식과 자존감에 미치는 효과를 알아보고자 하였다. 연구 대상은 인문계 여고 1학년 여학생들로서 ‘스트레스 관리를 위한 집단미술치료 프로그램’에 자발적으로 참여한 실험집단 12명과 통제집단 11명으로 구성되었다. 실험집단에게는 총 8회기의 해결중심 집단미술치료를 실시하였으며 회기 당 120분이 소요되었다. 측정도구는 사전, 사후에 스트레스 대처방식 검사, 자존감 검사, 빗속의 사람 투사그림검사를 사용하였고 2회기, 5회기, 8회기에 척도질문을 실시하여 그 점수의 변화를 분석하였다. 자료분석은 스트레스 대처방식과 자존감 점수는 공변량 분석을, 빗속의 사람 검사는 t검증과 질적 분석을, 시기에 따른 척도질문 점수 변화는 일원변량분석을, 프로그램 회기 과정은 질적 분석을 실시하였다. 연구 결과는 다음과 같다. 첫째, 프로그램 적용 후에 실험집단은 통제집단에 비해 정서완화적 대처방식과 소망적 사고 대처방식을 많이 사용하였다. 둘째, 빗속의 사람 검사에서 실험집단의 스트레스 대처능력이 통제집단보다 높아졌다. 셋째, 시기에 따른 척도질문 점수가 긍정적으로 변화하였다. 넷째, 실험집단은 통제집단에 비해 자존감이 높아졌다. 이와 같은 결과를 통해 해결중심 집단미술치료가 여고생의 스트레스 대처방식과 자존감에 긍정적인 효과를 미친다는 결론을 내릴 수 있다.

      • KCI등재

        Indigo carmine enhances phenylephrine-induced contractions in an isolated rat aorta

        최윤숙,옥성호,이승민,박상승,하유미,장기철,김혜정,신일우,손주태 대한마취통증의학회 2011 Korean Journal of Anesthesiology Vol.61 No.1

        Background: The intravenous administration of indigo carmine has been reported to produce transiently increased blood pressure in patients. The goal of this in vitro study was to examine the effect of indigo carmine on phenylephrine-induced contractions in an isolated rat aorta and to determine the associated cellular mechanism with particular focus on the endothelium-derived vasodilators. Methods: The concentration-response curves for phenylephrine were generated in the presence or absence of indigo carmine. Phenylephrine concentration-response curves were generated for the endothelium-intact rings pretreated independently with a nitric oxide synthase inhibitor, Nω-nitro-L-arginine methyl ester (L-NAME), a cyclooxygenase inhibitor, indomethacin, and a low-molecular-weight superoxide anion scavenger, tiron, in the presence or absence of indigo carmine. The fluorescence of oxidized dichlorofluorescein was measured in rat aortic vascular smooth muscle cells cultured in the control, indigo carmine alone and tiron plus indigo carmine. Results: Indigo carmine (10^-5 M) increased the phenylephrine-induced maximum contraction in the endotheliumintact rings with or without indomethacin, whereas indigo carmine produced a slight leftward shift in the phenylephrine concentration-response curves in the endothelium-denuded rings and L-NAME-pretreated endothelium-intact rings. In the endothelium-intact rings pretreated with tiron (10^-2 M), indigo carmine did not alter phenylephrine concentration-response curves significantly. Indigo carmine (10^-5 M) increased the fluorescence of oxidized dichlorofluorescein in the vascular smooth muscle cells, whereas tiron abolished the indigo carmineinduced increase in oxidized dichlorofluorescein fluorescence. Conclusions: Indigo carmine increases the phenylephrine-induced contraction mainly through an endotheliumdependent mechanism involving the inactivation of nitric oxide caused by the increased production of reactive oxygen species.

      • KCI등재

        마음챙김기반 인지치료(MBCT) 프로그램이 간호대학생의 스트레스, 자아존중감 및 우울에 미치는 영향

        최윤숙,김명아 한국콘텐츠학회 2019 한국콘텐츠학회논문지 Vol.19 No.2

        The purpose of this study was to identify the effectiveness of Mindfulness-Based Cognitive Therapy(MBCT) program on stress, self-esteem and depression of nursing college students. Thirty-eight students were enrolled by convenience sampling in this study and allocated to control (n=20) and experimental group (n=18). In the intervention group, Mindfulness-Based Cognitive Therapy program was applied over 8 sessions, while the control group received material of MBCT program. The data were analyzed using the Independent t- test, Chi-square test and Fisher‘s exact test. There was significant difference in stress and depression between the groups, but the self-esteem did not show any significant effect. The results showed that MBCT program is effective to regulate stress and depression of nursing college students and a further study is needed to explore the effect of MBCT program on stress and depression of nursing college students. 본 연구는 마음챙김기반 인지치료(Mindfulness-Based Cognitive Therapy, MBCT) 프로그램이 간호대학생의 스트레스, 자아존중감 및 우울에 미치는 효과를 규명하고자 시도된 비동등성대조군전후 유사실험 연구이다. 연구대상자는 경기도 S시에 소재한 간호대학 3학년 38명으로 실험군 18명과 대조군 20명으로 구성하였다. 실험군은 총 8회기에 걸쳐 MBCT 프로그램을 적용하였고 스트레스, 자아존중감 및 우울에 대해 두 집단의 차이를 규명하였는데 연구 결과 MBCT 프로그램의 스트레스와 우울에 대한 유의미한 효과가 규명되었으나 자아존중감은 유의미한 효과가 나타나지 않았다. 따라서 MBCT 프로그램이 간호대학생이 대학생활에서 경험하는 스트레스와 우울에 영향을 미칠 수 있는 중재임을 알 수 있었다. 이를 근거로 간호대학생의 스트레스와 우울을 감소시키기 위한 중재방안으로 제언하였다.

      • KCI등재

        A case of back pain caused by Salmonella spondylitis -A case report-

        최윤숙,조우진,윤소희,이성윤,박상현,박종국,장은희,신혜영 대한마취통증의학회 2010 Korean Journal of Anesthesiology Vol.59 No.-

        Salmonella spondylitis is a rare illness, and it generally occurs in patients who have already had sickle cell anemia,and it is even rarer in patients who are without sickle cell anemia. A 61-year-old male patient was hospitalized for the evaluation of his renal function and then treatment was started for his back pain. His back pain had developed about 2 months previously without any specific trauma. Only a bulging disc was detected on the initial lumbar MRI. Regarding his fever, it was diagnosed as possible atypical pneumonia, scrub typhus, etc., and multiple antibiotic therapy was administered. At the time of transfer, the leucocytes and hs-CRP were normal and the ESR was elevated. A diagnostic epidural block was performed for his back pain, but his symptoms were not improved. Lumbar MRI was performed again and it showed findings of infective spondylitis. Salmonella D was identified on the abscess culture and so he was diagnosed as suffering from Salmonella spondylitis. After antibiotic treatment, his back pain was improved and the patient was able to walk.

      • Aminoglycoside系 抗生物質과 Na-Alginate 製劑 倂用에 의한 相互作用

        최윤숙,이상헌,김재백 圓光大學校 藥品硏究所 1986 藥品硏究所報 Vol.1 No.1

        In clinic, a drug administers to patients by the ad-mixed injection or the coincidental administration of intravenous and intramuscular injection. Thin drug toxicity or effect may be changed by the interaction. We thought that the coincidental administration of aminoglysoside antibiotics and Na-alginate preparation effected for renal function and renal tissue. So nave experimented on the renal damage in rabbits. which the coincidental adminstration of antibiotics and Na-alginate was been done. by microscopic finding blood urea nitrogen levels and creatinine levels. The results were as follows, 1) In intramuscular injection, nephrotoxicity of Amikacin was less than kanamycin. 2) As the coincidental administration of antibiotics (kanamycin or Amikacin) and Na-alginate preparation was been done, acute renal failure was significantly produced. 3) Characteristic morphological finding of this acute renal failure were identified by necrosis of proximal convoluted tubular cells and in early stage the appearance of PAS positive. 4) In this results, the produced material by interaction of Amikacin and Na-alginate preparation increased the nephrotoxicity as same as kanamycin.

      • KCI등재

        Insulin effect on bupivacaine-induced cardiotoxicity in rabbits

        최윤숙,이국현 대한마취통증의학회 2011 Korean Journal of Anesthesiology Vol.61 No.6

        Background: Resuscitation following bupivacaine-induced cardiovascular collapse is difficult and often refractory to conventional treatment. This study was performed to assess the effect of insulin on bupivacaine-induced cardiovascular collapse in pentobarbital-anesthetized rabbits. Methods: Bupivacaine was administered at 0.75 mg/kg/min until the heart rate decreased to 65 beats/min. A bolus of regular insulin (2 U/kg) was administered intravenously at the bupivacaine infusion endpoint (BIE) in the insulin group (n = 8), and 2 mL of 0.9% NaCl was administered to the control group (n = 8). Results: All animals in the insulin group survived and four animals died in the control group. Arrythymia was rare 10minutes after the BIE in the insulin group. Conclusions: Bupivacaine-induced cardiovascular collapse can be effectively reversed with an insulin injection,probably through facilitation of cardiac conduction and contraction.

      • KCI등재

        db/db 마우스에서 IH-901의 항 당뇨 활성

        최윤숙,한기철,한은정,박금주,박종석,성종환,정성현,Choi, Yun-Suk,Han, Gi-Cheol,Han, Eun-Jung,Park, Keum-Joo,Park, Jong-Suk,Sung, Jong-Hwan,Chung, Sung-Hyun 대한약학회 2006 약학회지 Vol.50 No.6

        The pharmacological properties of ginseng are mainly attributed to ginsenosides, the active constituents that are found in the extracts of different species of ginseng. Lately; the studies on ginsenosides are mainly focused on IH-901, a major intestinal bacterial metabolite of ginsenosides. In this study; we examined the anti-diabetic activity of IH-901 in C57BU61 db/db mice model. IH-901 was administrated orally at a dose of 20 mg/kg for 5 weeks. During the experimental period, body weight and blood glucose levels were measured every week. After 5 weeks, db/db mice were sacrificed and diabetic parameters were analyzed. IH-901 treated group showed a significant decrease in fasting blood glucose levels (from 10.5 mM to 9.4 mM), insulin resistance index (from 163.6 to 100.2) and triglyceride levels (from 115.3 to 70.1) compared to the diabetic control. In Pancreatic islets morphology; IH-901 treated group revealed much less infltrated mononuclear cells, indicating that IH-901 recovered ${\beta}$-cell damage due to hyperglycemia. In addition, IH-901 upregulated expressions of glucose transporter 4 (GLUT4) and PPAR-${\gamma}$ in skeletal muscle and adipose tissue, respectively. Taken together IH-901might be a potential anti-hyperglycemic agent with insulin sensitizing effect.

      • KCI등재

        Epidemiology of Complex Regional Pain Syndrome: A Retrospective Chart Review of 150 Korean Patients

        최윤숙,이미금,이효민,이철중,조지연,전수영,이상철,김용철 대한의학회 2008 Journal of Korean medical science Vol.23 No.5

        Complex regional pain syndrome (CRPS) is a chronically painful and disabling disorder. However, no data are available even on the epidemiology of CRPS in Korea. This study was undertaken to retrospectively assess the epidemiologic characteristics of CRPS in 150 consecutive patients at a tertiary chronic pain center from March 2002 to February 2006. Information was obtained regarding patients’ demographics, nature of injury, and treatment modalities. Seventy-one percent of patients had CRPS type I. The mean 11-point verbal numerical rating scale score at initial examinations and at the time of study were 8.0 and 5.7, respectively. Thirty-two percent of patients showed no change or increase in pain intensity during follow-up at our pain center. The mean duration of CRPS symptoms prior to our pain center evaluation and prior to the time of study were 27 months and 50 months, respectively. These patients had seen on average 5 different physicians before being referred to our center. This study shows that the majority of CRPS patients were referred to our center after more than 2 yr of symptoms. The clinical implication of such delayed transfer and strategies to avoid this problem are discussed.

      • KCI등재후보

        무릎전치환술 환자에서 일회성 복재신경차단술이 수술 후 출혈량 감소에 미치는 영향

        최윤숙,윤소희,조승연,송승은,김상림,Choi, Yun Suk,Yun, So Hui,Cho, Seung Yeon,Song, Seung Eun,Kim, Sang Rim 제주대학교 의과학연구소 2021 The Journal of Medicine and Life Science Vol.18 No.1

        In elderly patients, the vital parameters tend to fluctuate based on the blood volume status, which may cause sudden hypovolemic shock if the postoperative bleeding continues. Particularly, those who undergo surgery for arthritis needs to pay extra attention because the bleeding may persist over the joints after the surgery. Therefore, appropriate pain control is required to reduce the postoperative blood loss. This retrospective chart review study was conducted to assess the postoperative pain control and reduction of blood loss with a single injection of saphenous nerve block (SNB) in elderly patients with osteoarthritis. We reviewed the electronic medical records of patients who underwent knee total arthroplasty with spinal anesthesia between January and May 2016. A total of 51 patients participated in this study. All patients were treated with intravenous patient-controlled analgesia for the postoperative pain control, and additional analgesic agents were administered at a visual analogue scale above a score of 6. In 25 patients, SNB was performed using ultrasound with the administration of 0.75% ropivacaine (15 mL) after the surgery. Patients who received additional analgesics were significantly low in the nerve block group (P=0.009). Additionally, the volume of blood loss from catheter drainage was significantly low at 2 and 3 days postoperatively (P=0.013 and P=0.041, respectively) in the nerve block group. In patients who underwent total knee arthroplasty with osteoarthritis, only a single injection of saphenous nerve block was sufficient for the postoperative pain control and reduced bleeding.

      • KCI등재

        코로나19 팬데믹이 간호대학생의 대학생활적응에 미치는 영향 : 공감능력, 지각된 스트레스, 회복탄력성을 중심으로

        최윤숙,김미영 대한통합의학회 2024 대한통합의학회지 Vol.12 No.1

        Purpose : In this study, we aimed to determine the impact of the COVID-19 pandemic on nursing students' adjustment to college life by focusing on their empathic ability, perceived stress, and resilience. Methods : We applied a descriptive survey research design, which included a self-report questionnaire. The participants comprised 307 nursing students in B city. The data were analyzed by calculating the percentages, means, standard deviations, t-tests, ANOVA, Scheffé test, Pearson's correlation coefficients, and hierarchical regression using SPSS 23.0. Results : The participants' empathic ability score was 3.30±.42, perceived stress score 1.85±.49, resilience score 3.44±.64, and adjustment to college life score 3.25±.52. Adjustment to college life was positively correlated with resilience (r=.43, p<.001) but negatively correlated with perceived stress (r=.27, p<.001). Factors affecting adjustment to college life include, among general characteristics in Model 1, in descending order, major satisfaction-satisfied (β=.54, p<.001), interpersonal conflict: never (β=.26, p=.018), health status: healthy (β=.25, p=.002), character: positive (β=.21, p=.006), character: optimistic (β=.19, p=.015), parents' economic power: high (β=.15, p=.047), and gender: male (β=.11, p=.016). Model 1 was statistically significant (F=11.67, p<.001), and the explanatory power was 41 %. In Model 2, empathic ability, perceived stress, and resilience were added as independent variables. When including the dependent variables, the factors that most influenced adjustment to college life were perceived stress (β=-.37, p<.001), major satisfaction-satisfied (β=.36, p<.001), health status-healthy (β=.25, p<.001), gender-male (β=.10, p=.015), and resilience (β=.10, p=.029). Model 2 was statistically significant (F=17.65, p<.001), and the explanatory power was 56 %. Conclusion : We found that gender, major satisfaction, health status, perceived stress, and resilience affected adjustment to college life among nursing students who had experienced the COVID-19 pandemic. To increase their ability to adjust to college life, a gender-specific intervention program should be developed that can improve the students' health status, major satisfaction and resilience, and reduce their perceived stress.

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