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권두한(Dur Han Kwon),김만배(Man Bae Kim),윤도영(Do Young Yoon),이영희(Young Hee Lee),김재화(Jae Wha Kim),이희구(Hee Gu Lee),최인성(In Seong Choi),임종석(Jong Seok Lim),최용경(Yong Kyeung Choe) 한국약용작물학회 2003 한국약용작물학회지 Vol.11 No.1
Aqueous extracts form eleven species of Korean medicinal plants were screened for antiviral activity against transmissble gastroenteritis virus (TGEV) and porcine epidemic diarrhae virus (PEDV). Seven of eleven plant extracts were found to have cytotoxicity for ST cells at the concentration of 1㎎/ml, and ten extracts except Ephedra sinica were found to have non-cytotoxicity for Vero cells at the same concentration. Extracts of Znthoxylum piperium, Cudrina tricuspidata, Clerodendron trichomum, Sophora flavescens, effectively inhibited TGEV, respectively. There were the antiviral activity aganist TGEV in the extracts of Glesdistsia sinensis, Euonymus alatus, Ficus carica, Solanum nigrum, Ephodra sinica, Xanthium strumarium, and Acanthopanax seeliflorus in spite of their cytotoxicities. Nine extracts except Xanthium strumarium and Acanthopanax seeliflorus were found to have the antiviral activitity against PEDV. Extracts of Zanthoxylum piperium, Sophora flavescens was shown to have antiviral activities against both TGEV and PEDV.