ABO 혈액형 기록 불일치로 적발된 신분 도용 사례

최수인,신희봉,조덕,최수인 대한수혈학회 2019 大韓輸血學會誌 Vol.30 No.1

アルバイトをした後

최수인 덕성여자대학교 일어일문학회 1986 語り合い Vol.3 No.-

단일 상급종합병원에서 여러 수혈전검사 프로토콜 운영 경험

최수인,조덕,신성환,서지영,유홍비,천세종 대한수혈학회 2018 大韓輸血學會誌 Vol.29 No.2

Background: Pretransfusion tests are essential for safe transfusions, but occasionally, part or all can be omitted when a transfusion is needed urgently in an emergency. The purpose of this study was to share the authors’ experience of various pretransfusion test protocols in a tertiary referral hospital in Korea. Methods: From July 2016 to June 2017, all transfusion cases at Samsung Medical Center were analyzed retrospectively. For each pretransfusion test protocol, the parameters regarding issue, return and disposal rate of blood products, occurrence of hemolytic transfusion adverse effect, and prescription frequency of each respective department and ordering site were analyzed. Results: A total of 90,539 units of red blood cells, 24,814 units of fresh frozen plasmas, 24,758 units of single donor platelets, and 23,303 units of platelet concentrates were issued during the study period. Among them, 3.6%, 1.8%, 0.3%, and 0.4% of red blood cells, fresh frozen plasmas, single donor platelets, and platelet concentrates were issued according to the emergency transfusion protocols. When various pretransfusion test protocols were applied to issue blood products, there was no case in which an adverse hemolytic transfusion reaction was suspected. When compared with usual pretransfusion test protocol, all emergency transfusion protocols showed significantly higher return and wastage rates in red blood cells and fresh frozen plasmas. Platelets also had a higher return and wastage rate, but the difference was not significant. Conclusion: These results suggests that there is no different risk of adverse hemolytic transfusion reaction regardless the pre-transfusion protocols, but management about of the increased rate of return and wastage of blood products in emergency transfusions should be considered.

First Report of Neutrophil Involvement of Exflagellated Plasmodium vivax Microgametes

최수인,전병열,이용화,신희봉,이유경 대한진단검사의학회 2014 Annals of Laboratory Medicine Vol.34 No.6

Dear editor Malarial infections pass through multiple stages, beginning in the hepatic parenchymal cells where invading sporozoites ma- ture into schizonts. On maturation, these schizonts rupture and release merozoites into the bloodstream, which, in turn, target erythrocytes, leading to the clinical manifestations of the disease [1]. Exflagellation is characterized by thin, flagella-shaped mi- crogametes emerging from male malaria gametocytes; occurs in the midgut of the Anopheles mosquito; and has rarely been observed in peripheral blood specimens.

Two Cases of Fungemia after Endoscopic Variceal Obturation for Gastric Variceal Bleeding

최수인,윤아일린 연세대학교의과대학 2021 Yonsei medical journal Vol.62 No.2

Fever is a common complication of endoscopic variceal obturation (EVO) therapy for gastric variceal bleeding. However, fungemiarelated to EVO therapy has not yet been reported. Herein, we report two cases of post-EVO fungemia in cirrhotic patientswho underwent therapeutic EVO for gastric variceal bleeding. Both patients developed sustained high fever after repeated EVOprocedures while on prophylactic antibiotic use. In both patients, blood cultures revealed yeast, and they were finally diagnosedwith Candida infection. Candida is a common member of the intestinal flora; however, it can cause invasive infection with consequentpoor prognosis in cirrhotic patients. The route of Candida invasion is unclear; however, repeated EVO may predisposepatients to Candida infection, particularly those who are in the end stage of liver disease and receiving prophylactic antibiotics. Our cases highlight that repeated invasive procedures can increase the risk of fungal infections, and fungemia should be consideredin the differential diagnosis of post-EVO fever.

Relationship between Regional Body Fat Distribution and Diabetes Mellitus: 2008 to 2010 Korean National Health and Nutrition Examination Surveys

최수인,정다은,임정수,이미영,신장열,정춘희,허지혜 대한당뇨병학회 2017 Diabetes and Metabolism Journal Vol.41 No.1

Background The aim of this study was to investigate the association between regional body fat distribution, especially leg fat mass, and the prevalence of diabetes mellitus (DM) in adult populations. Methods A total of 3,181 men and 3,827 postmenopausal women aged 50 years or older were analyzed based on Korea National Health and Nutrition Examination Surveys (2008 to 2010). Body compositions including muscle mass and regional fat mass were measured using dual-energy X-ray absorptiometry. Results The odds ratios (ORs) for DM was higher with increasing truncal fat mass and arm fat mass, while it was lower with increasing leg fat mass. In a partial correlation analysis adjusted for age, leg fat mass was negatively associated with glycosylated hemoglobin in both sexes and fasting glucose in women. Leg fat mass was positively correlated with appendicular skeletal muscle mass and homeostasis model assessment of β cell. In addition, after adjusting for confounding factors, the OR for DM decreased gradually with increasing leg fat mass quartiles in both genders. When we subdivided the participants into four groups based on the median values of leg fat mass and leg muscle mass, higher leg fat mass significantly lowered the risk of DM even though they have smaller leg muscle mass in both genders (P<0.001). Conclusion The relationship between fat mass and the prevalence of DM is different according to regional body fat distribution. Higher leg fat mass was associated with a lower risk of DM in Korean populations. Maintaining leg fat mass may be important in preventing impaired glucose tolerance.

Electrophysiologic Investigation During Facial Motor Neuron Suppression in Patients With Hemifacial Spasm: Possible Pathophysiology of Hemifacial Spasm: A Pilot Study

최수인,김민욱,박동윤,허륭,장대현 대한재활의학회 2013 Annals of Rehabilitation Medicine Vol.37 No.6

Objective To evaluate the pathophysiological mechanism of hemifacial spasm (HFS), we performed electrophysiological examinations, such as supraorbital nerve stimulation with orbicularis oris muscle recording and lateral spread tests, after suppressing the patient’s central nervous system by administering intravenous diazepam.Methods Six patients with HFS were recruited. Supraorbital nerve stimulation with orbicularis oris muscle recording and the lateral spread test were performed, followed by intravenous application of 10 mg diazepam to achieve facial motor neuron suppression. Subsequently, we repeated the two electrophysiological experiments mentioned above at 10 and 20 minutes after the patients had received the diazepam intravenously.Results Orbicularis oris muscle responses were observed in all patients after supraorbital nerve stimulation and lateral spread tests. After the diazepam injection, no orbicularis oris muscle response to supraorbital nerve stimulation was observed in one patient, and the latencies of this response were evident as a slowing tendency with time in the remaining five patients. However, the latencies of the orbicularis oris muscle responses were observed consistently in all patients in the lateral spread test.Conclusion Our results suggest that ectopic excitation/ephaptic transmission contributes to the pathophysiological mechanisms of HFS. This is because the latencies of the orbicularis oris muscle responses in the lateral spread test were observed consistently in the suppressed motor neuron in our patients.

컴퓨터 시스템 설치를 위한 위치-할본-규모결정 모형

최수인,Choe, Su-In 한국전자통신연구원 1983 전자통신 Vol.5 No.3

복수 설비입지 문제의 한 유형인 컴퓨터 시스템 설치문제는 설치위치의 결정, 서비스 지역의 할본, 각 시스템의 규모 결정 등 복합적인 의사결정 과제를 안고 있다. 이 세가지 의사결정 문제는 상호 밀접하게 연결되어 있으므로 세 문제를 동시에 고려하여 전체적으로 최적화할 수 있는 해를 구하도록 해야하는 데 이는 매우 어려운 일이다. 그러므로 지금까지는 각각의 최적해를 독립적으로 구한 후 이를 적당히 결합한다거나 또는 아예 최적해를 구하기 보다는 만족할 만한 적정해를 구함으로써 만족할 수 밖에 없었다. 본 연구에서는 이러한 한계를 극복하기 위해 컴퓨터 시스템 설치에 있어서의 location-Size결정모형을 구축함으로써 이러한 의사결정 문제의 수리적 최적해를 구하고자 했다. 이 모형은 선형 및 비선형의 제약조건을 갖는 non-linear programming 문제로 수식화 되었으며, penalty function method, feasible conjugate, direction methods, branch & bound technique등의 algorithm들을 단계적으로 사용함으로써 최적해의 도출이 가능하게 되었다. 실제 문제에 적용한 결과 유용성은 충분한 것으로 보여졌으나 해법상의 개선을 통해 계산노력을 줄이도록 함이 요구 되었다. In the area of computer network planning, a location-allocation-size problem is involved. Since multi-facility location-allocation-size problems are very complex in formulating a mathematical model, it is a usual practise to adopt alternative approaches, which give no optimal results, instead of the optimal solution by mathematical approach. In this article, however, an attempt is made to formulate a mathematical model for the decision making problem of computer network design.

전암성 병변인 위선종 자연 경과와 치료 전략

최수인,박준철 대한상부위장관ㆍ헬리코박터학회 2018 Korean Journal of Helicobacter Upper Gastrointesti Vol.18 No.2

The concept and pathological diagnostic criteria of gastric adenoma (dysplasia) differ between Western countries and Japan, and discrepancies between histopathological examinations before and after endoscopic resection may occur. Therefore, the natural history of adenoma should be interpreted and the treatment strategy of adenoma established. It is recommended that endoscopic resection be performed for high-grade dysplasia due to the potential higher risk of progression to carcinoma. For low-grade dysplasia, the risk of malignant transformation is relatively low. However, resection is considered the first approach for the purpose of diagnosis and treatment. If resection is not feasible, the alternative may be to use argon plasma coagulation for selected lesions that are less likely to be malignant. When Helicobacter pylori infection is detected, eradication therapy is recommended to reduce the risk of metachronous lesions. Post-resection follow-up should be performed within 1 year to detect synchronous lesions and then follow-up endoscopy at 1 or 2-year intervals may be considered for metachronous lesions. (Korean J Helicobacter Up Gastrointest Res 2018;18:103-109)

Planned Transfusion of D-Positive Blood Components in an Asia Type DEL Patient: Proposed Modification of the Korean National Guidelines for Blood Transfusion

최수인,천세종,서지영,양지혁,조덕 대한진단검사의학회 2019 Annals of Laboratory Medicine Vol.39 No.1

DEL type red blood cells (RBCs) are characterized by the expression of extremely low levels of D-antigen, and thus, they cannot be detected by routine serologic D typing or a weak D test but are revealed by RHD genotyping or adsorption-elution studies [1]. The most common DEL phenotype is RHD (NM_016124.4: c.1227G>A), which is also referred to as Asia type DEL [2] and accounts for 94.7% of all Korean DEL cases [1]. Although DEL is a rare phenotype in individuals of European ethnicity [3], it is found in approximately 10–33% of serologically D-negative East Asian individuals of serologically D-negative East Asian individuals [1].