2000년도 부산지역에서 분리된 살모넬라속균의 혈청학적 분포 및 항균제 감수성

차인호,민상기,박은희,김미희,진성현,박지현,이영숙,이상훈 한국생명과학회 2001 생명과학회지 Vol.11 No.3

A total of 79 Salmonella spp. were isolated from Pusan area in 2000. The serotypes of 79 Salmonella isolates were classified as 42 strains of S. typhi(53.1%), 24 strains of S. enteritidis(30.4%), 9 strains of S. montevideo(11.4%), 2 strains of S. typhimurium(2.5%), 1 strain of S. infantis(1.3%) and 1 strain of S. indiana(1.3%) strains(16.5%) of Salmonella sp. were isolated at May July, respectively. The isolates of S. typhi were sensitive to most sntibiotics except streptomycin. All isolates of S. typhi were especially sensitive to tobramycin, gentamicin, colistin, kanamycin, samikacin, sulfamethozazole/ trimethoprim, cefriaxone, ceftazdime, cifrofloxacin, cefoxitin and cefotaxime. Isolates of S. enteritidis wer presented higher resistance than isolates of S. typhi. Twenty-four strains of S. enteritidis were sensitive to kanamycin, amikacin cifrofloxacin, cefoxitin and cefotaxime, however 13 strains(54.2%) of S. enteritidis were resistant to carbenicillin, ampicillin and ticarcillin. Nine strains of S. montevideo were sensitive to most antibiotics except carbenicillin and streptomycin. Each 1 stain of S. indiana and S. infantis was sensitive to most antibiotics used in this study except streptomycin. Three kinds of resistant pattern (CB, SM, TE, AM, TC). In the case of S. enteritidis isolates, 9 kinds resistant pattern were detected. Most frequent resistant pattern of S. enteritidis isolates was CB, AM, TC type(16.7%)

북유럽과 모던 클래식 스타일의 조화, 판교 주택

차인호 전우문화사 2017 전원주택 라이프 Vol.2017 No.10

Polymorphisms of CYP1A1 and GSTM1 Genes and Susceptibility to Oral Cancer

차인호,박종윤,정원윤,최민아,김형준,박광균 연세대학교의과대학 2007 Yonsei medical journal Vol.48 No.2

Purpose: Oral cancer is the fifth most common form of cancer in the world and comprises 6.5% of all cancer deaths. Since one of the major risk factors for oral cancer is tobacco use, we hypothesized that polymorphic genes coding for tobacco carcinogen-metabolizing enzymes may play a role in oral cancer susceptibility. Materials and Methods: To investigate the association between polymorphisms of the CYP1A1 and GSTM1 genes and risks for oral squamous cell carcinoma (OSCC) in the Korean population, the prevalence of the CYP1A1 Mspl and GSTM1 null polymorphisms were examined in 72 patients with histologically confirmed primary OSCC, as well as in 221 healthy control subjects. Results: A significant risk increase for oral cancer was observed among subjects with the homozygous CYP1A1 (m2/m2) genotype (OR=3.8, 95% CI=1.9-7.7), but not the GSTM1 null genotype (OR=0.7, 95% CI=0.4-1.3). Risk for oral cancer was significantly increased in subjects with the homozygous CYP1A1 (m2/m2) genotype, regardless of smoking history (smokers; OR=4.4; 95% CI=1.2-16.3; non- smokers OR=4.9; 95% CI=1.9-12.5). Using the potentially most protective genotype GSTM1 (+)/CYP1A1 [(m1/m1)+ (m1/m2)] as the reference group, an increased risk for oral cancer was observed among subjects with the GSTM1 (+)/ CYP1A1 (m2/m2) (OR= 2.0, 95% CI=0.8-5.2), and GSTM1 (-)/ CYP1A1 (m2/m2) (OR=4.9, 95% CI=1.5-15.5) genotypes (p<0.009, (χ2 trend test). Conclusion: Our results suggest that individuals with a genotype of CYP1A1 (m2/m2) and GSTM1 (-) are highly susceptible for OSCC and that the CYP1A1 (m2/m2) genotype is closely associated with increased risk of OSCC in Koreans.

골목길 공공조명환경 디자인의 문제와 대안 - 서울 종로구 명륜길 사례를 중심으로 -

차인호 한국실내디자인학회 2019 한국실내디자인학회논문집 Vol.28 No.1

In most of lighting research is focused on methods for securing efficiency of lighting system and brightness of light. Therefore, this study analyzed from time, human, and space to solve the problem of public lighting system which directly helps the daily life of local residents. And pointed out the quantitative shortage of light, the securing of sight for flowing line at night, the unpleasant glare and the problem of light pollution. Most importantly, we can identify the local lighting problem that be said simply uncomfortable due to darkness and security reasons. Because local resident can not able to identify the problem correctly. In terms of space, street lighting was installed, but the quantitative imbalance was heavy in each section. In addition, the accessibility of the space is reduced because the vertical elements of light are not secured. There are also the public and private areas of the lighting and particularly the commercial space, it is a problem that unnecessary public lighting are invaded. This research has important meaning as a basic research to open a methodology to solve the qualitative problems of light required in everyday public lighting.

마우스의 DMBA-TPA유도 피부 전암병소에서 Bleomycin의 효과

차인호,박소연,육종인,박광균,이은하,홍준철,김진 대한구강악안면병리학회 1996 대한구강악안면병리학회지 Vol.20 No.2

노변식품에서 분리한 Campylobacter jejuni의 특성에 관한 연구

차인호,김용환,빈재훈,하상태,김경숙,권혁동,이채남 한국식품위생안전성학회 1994 한국식품위생안전성학회지 Vol.9 No.3

화장품매장의 연색성개선을 위한 조명환경 디자인 연구

차인호 사단법인 한국브랜드디자인학회 2019 브랜드디자인학연구 Vol.17 No.1

These days, systematic lighting design has been required for comfort of the space, unlike past the lighting has been focused on the purpose of illuminating darkness or electric efficiency because at that time we think lighting system was only for darkness. 72% of the customers complain that the color of the cosmetics differs after purchasing. This problem is due to the lack of color rendering for reproduction of colors in store showcase. However, high color rendering lighting equipment has been avoided because of price. This study aims to present a environment that can replace high-priced color rendering lighting system, based on the relationship between level of illumination and color temperature. We measure the level of illumination and color temperature of the 20 cosmetics stores and organize the calculated data. And make customer interviews to find out suitable environment in visual perception. High color rendering property close to nature was secured in 4800Lx and 5500 K. With the lighting environment of the optimum level of illumination and color temperature conditions, concrete design methodology can be realized and applied, especially in general commercial space where is hard to be applied high quality color rendering system because of high price. And also in costume room, design office, museum can be operated in low cost. 조명을 단순히 어두움을 밝히는 목적으로만 인식하여 전기에너지적 효율이나 밝기감 확보에만 집중했던 과거와 달리 공간의 질적 쾌적함을 위한 빛의 체계적 설계가 요구되고 있다. 72%의 고객이 화장품 매장에서 구매한 색조화장품의 색상이 구매이후 달라보여서 불편함을 겪었다고 호소한다. 이 같은 문제는 화장품매장의 색조화장품 쇼케이스의 피부착색테스트용 조명환경에 원색재현을 위한 연색성이 절대적으로 부족하기 때문이다. 하지만 고연색성 조명장비는 높은 가격으로 매장의 관리자나 점주입장에서 적용을 기피하고 있다. 이 연구는 조도와 색온도의 관계성에 의거하여 고가의 고연색성 조명을 대신할 수 있는 빛의 환경을 제시하고자 한다. 이를 위해 서울도심과 부도심의 화장품매장 20곳에 대한 조명환경의 문제를 유형화하였으며 조도와 색온도를 측광하여 산출된 자료를 정리하고, 그 수치에 대한 검증절차로 방문고객을 대상으로 FGI를 실시하여 시지각 인지의 관점에서 적합한 조명조건을 규명하였다. 그 결과, 조도 4800Lx, 색온도 5500 K 의 조건에서 자연광조건에 가까운 높은 연색성을 확보할 수 있었고 매장방문 고객을 대상으로 한 평가조사에서도 이 조건의 연색적정성이 가장 높게 평가되었다. 이 연구를 통해 밝혀진 적정 조도와 색온도조건의 조명환경으로 고연색성 조명장비가 필요하지만 높은 가격 때문에 적용하기 힘들었던 일반 상업공간을 비롯하여 의상실, 디자인사무실, 저예산으로 운영되는 미술관, 박물관, 전시관에서도 합리적 비용으로 쾌적한 시각적 인지환경을 연출할 수 있는 구체적 설계방법론을 구현하고 응용할 수 있게 될 것으로 기대한다.

구강악안면외과 영역에서의 MIDFACIAL DEGLOVING APPROACH의 유용성

차인호,윤현중,이의웅,Cha, In-Ho,Yoon, Hyun-Joong,Lee, Eui-Wung 대한악안면성형재건외과학회 1998 Maxillofacial Plastic Reconstructive Surgery Vol.20 No.3

Midfacial degloving approach의 장점으로는 비강, 비중격, 상악동, 사골동, 접형골동, 비인두 부위 병소의 접근에 좋은 시야를 제공하며, 수술방법이 기존의 방법에 비해 수월하고, 두피관상 절개법, 측두부 절개법, 구개부 절개법과 함께 사용하여 수술시야를 넓힐 수 있으며, 안면부에 나타나는 흉터가 없어 심미적으로 만족스러우며 특히, Keloid 체질에서 유용하다는 것을 들 수 있다. 이에 저자 들은 구강악안면외과 영역에서도 중안면부 외상, 두개안면부 기형 처치, 상악골 절제술을 요하는 경우, 상악골과 비골의 동시 수술을 요하는 경우 등에 midfacial degloving approach가 유용한 수술 접근 방법으로 사료되었다. In the treatment of maxillary lesion including a maxillary sinuses, most of oral and maxillofacial surgeons have used the vestibular incision or the Weber-Fergusson incision. However, the vestibular incision has disadvantage which it provides a rather limited exposure and the Weber-Fergusson incision leaves visible scar in the midface. Furthermore, because the scar is confined on unilateral side only, the technique is hesitated to apply especially in children, younger patients and women. Since Casson first introduced midfacial degloving technique, this approach has been used frequently to treat the lesion on nasal cavity, nasopharynx, skull base and paranasal sinuses by ENT surgeons. But, we think this technique can be used usefully in oral and maxillofacial regions. So, we experienced favorable results which it provided a proper exposure, no visible facial scar and it could be used on bilateral midfacial lesions.

한국인 성인에서 두정골의 부위별 두께에 대한 연구

차인호,김희진,정영수,이충국,정인혁,Cha, In-Ho,Kim, Hee-Jin,Jeong, Young-Soo,Yi, Choong-Kook,Chung, In-Hyuk 대한악안면성형재건외과학회 1998 Maxillofacial Plastic Reconstructive Surgery Vol.20 No.3

To clarify the clinical utility of the calvarial bone graft in the maxillofacial reconstruction, we performed on anatomical study by measuring the regional thickness of the parietal bone on 17 Korean adult dry skulls. Before the sectioning the calvarium, the anatomical landmarks were marked on each specimens. And then we measured the total thickness of the parietal bone, the thickness of the outer and inner cortical plates on various points in each sections of parietal bones using a digital caliper under the stereomicroscope. The total thickness of the parietal bone was ranged from 5.17mm to 7.50mm, and there were no statistical difference in the total thickness of the parietal bone on the same points bilaterally. But there was a tendency that the thickness of the parietal bone was thicker toward to the lambda point than the coronal suture area. At the other hand, the thickness of the outer and inner plate of the parietal bone was the thickest at the first point of the right aspect on the line 1, the first point of the left aspect on the line 5, respectively. In conclusion, this study showed that the donor site of the parietal bone for the maxillofacial reconstruction should be located at more posterior and medial area of the parietal bone than the prevalent known donor site.

설사환자로부터 분리한 대장균의 혈청형 분포 및 항생제 내성유형

차인호,진성현,박은희,박성아,조현철,이영숙,정석훈,이영길,이상훈 한국생명과학회 2000 생명과학회지 Vol.10 No.3

설사환자에 대한 기초 역학자료의 일환으로 부산지역의 설사환자로부터 분리한 대장균의 혈청형 분 포와 항생제 내성유형을 확인한 결과 다음과 같은 성적을 얻었다. 1. 부산시 관내의 설사환자 1,239명의 분변으로부터 대장균을 분리한 결과 1,239명중 621명의 환자분변으로부터 721주의 대장균을 분리 동정 하였다. 2. 설사 환자의 월별 발생 분포는 8월에 131명으로 가장 높은 발생율을 나타낸 반면, 1월에 59 명으로 가장 낮은 발생율을 보였다. 그러나 1월에 발생한 설사환자를 제외하고는 계절에 크게 관계없이 연중 지속적으로 고른 발생 분포를 나타내었다. 연령별 발생분포는 1세 이하의 유아와 10세 이하의 어 린이가 633명으로 전체 설사환자의 50% 이상을 나타내었고, 50대의 경우 123명, 40대의 경우 114명, 60 대의 경우 99명, 30대의 경우 79명, 10대의 경우 74명, 20대의 경우 63명의 순으로 높은 발생율을 나타 내었으며 70세 이상의 노인들은 54명으로 가장 갖은 발생율을 보였다. 3. 혈청형별 분포는 혈청형 O44 가 121주(16.8%)로서 가장 높은 분포도를 나타내었으며, O153 (8.6%), O1(7.5%), 등에는 분리균 모두 내 성을 나타내었다. 공시약제에 대한 분리주의 내성유형은 14제 내성형(26.1%), 13제 내성형(22.3%), 12제 내성형(17.3%), 11제 내성형(14.8%), 10제 내성형(8.5%), 9제 내성형(6.0%) 등의 순으로 높은 분포를 보 였으며, 본 실험에 공시된 16종의 항생제에 대한 설사환자유래 대장균의 내성유형은 총 125종류로 분류 되었다. 특히 Am Cb Cl Co Cp Em Gm Mx Nb Pg St Tb Tc Tm 의 14제 내성형이 전체 분리균주의 24.3%로 가장 높은 내성유형을 나타내었다. As a part of investigation for basic epidemiology of diarrheogenic disease, we attempted isolation of Escherichia coli from patients with diarrhea. Seven hundred and twenty-one strains of E. coli were isolated from 1,239 patients with diarrhea. Seasonal distribution of patient with diarrhea was shown the most high at August (18.2%). Age group distribution of patient was shown the most high at children (54.6%, 2 to 10 years old). The serotypes of 721 E. coli isolates were in order of serotype O44 (16.8%), O153 (8.6%), O1 (7.5%), O166(5.7%), O8 and O86a (4.7%), and O125 (4.6%). The supernates cultured 36 strains among 721 E. coli isolates were indicated cytotoxicity against monolayered Vero cells. All of the isolates were susceptible to amikacin. The isolates were resistant in order of novobiocin (99.0%), moxalactam (97.1%), carbenicillin (96.1%), tetracycline (90.4%), ampicillin (85.9%), gentamicin (84.0%), streptomycin (78.4%), cephalothin (46.6%) and polymyxin B (4.2%). In the antibiotic resistant patterns, 125 kinds of multiple resistance patterns of E. coli isolates were detected. The highest resistant pattern was ampicillin-carbenicillin-chloramphenicol-cephalothin-erythro-mycin- gentamicin-moxalactam-novobiocin-penicillin G-streptomycin-tobramycin-tetracycline-tri methoprim type (24.3%).