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D-1,3-Dioxolane 및 D-1,3-Oxathiolane 피리미딘 뉴크레오사이드의 합성
홍준희(Joon Hee Hong),차마리(Ma Rie Cha),신성은(Seong Eun Shin),최보길(Bo Gil Choi),정병호(Byung Ho Chung),김중협(Joong Huyup Kim),이종교(Chong Kyo Lee),정원근(Won Keun Chung),천문우(Moon Woo Chun) 대한약학회 1994 약학회지 Vol.38 No.6
We synthesized D-1,3-dioxolanyl acetate from D-mannose using Frazer-Reide reaction and D-1,3-oxathiolanyl acetate from either D-mannose or D-galactose in good yields. These acetates were conjugated with various disilylated pyrimidine base using trimethylsilyl trifluoromethane sulfonate as a Lewis acid catalyst to obtain 32 different D-nucleosides.
D-1,3-Dioxolane 및 D-1,3-Oxathiolane 피리미딘 뉴크레오사이드의 합성
정병호,이종교,김중협,최보길,홍준희,차마리,신성은,정원근,천문우 전남대학교 약품개발연구소 1995 약품개발연구지 Vol.3 No.1
We synthesized D-1,3-dioxolanyl acetate from D-mannose using Frazer-Reide reaction and D-1,3-oxathiolanyl acetate from either D-mannose or D-galactose in good yields. These acetates were conjugated with various disilylated pyrimidine base using trimethylsilyl trifluoromethane sulfonate as a Lewis acid catalyst to obtain 32 different D-nucleosides.