http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
주형로,양선모,박찬흠,김현웅 대한이비인후과학회 2002 대한이비인후과학회지 두경부외과학 Vol.45 No.6
Lingual thyroid is the most comon benign ectopic thyroid tisue but is a rare clinical entity. This developmental anomaly is dysphagia due to obstruction or even hemorhage. These symptoms can occur at any time from infancy through adulthood. The clinical findings, laboratory tests, and radiographic imaging studies employed in confirming the diagnosis and in pla-nning appropriate treatment have been evaluated. The primary therapeutic goal is to restore thyroid function but surgical excision of the gland is reserved for more advanced cases of gland enlargement resulting in airway compromise, severe transcervical approach and summarized the principles of current management for this condition. (Korean J Otolaryngol 2002;45:628-31)
주형로,Chu, Hyung-Ro 대한후두음성언어의학회 2007 대한후두음성언어의학회지 Vol.18 No.2
Otolaryngological manifestations of acid reflux include a wide range of pharyngeal and laryngeal symptoms ; and the constellation of symptoms has been called laryngopharyngeal reflux (LPR). In the absence of definite diagnostic criteria, LPR disease remains a subjective entity. A diagnosis of LPR is usually based on response of symptoms to empirical treatment. Investigative modalities such as pH monitoring and, more recently, impedance studies are generally reserved for treatment failures. LPR usually requires more aggressive and prolonged treatment to achieve regression of both symptoms and laryngeal findings. The suppression of gastric acid and secretion with anti-secretary agents has been the mainstay of medical treatment for patients with acid-related disorders. The suppression of gastric acid secretion achieved with Hz-receptor antagonist $(H_2RA)$ has proved suboptimal for relief of reflux symptoms. The rapid development of tolerance and rebound acid hypersecretion after the with-drawal of $H_2RA$ limit their clinical use. Proton pump inhibitors (PPI) have been proved to be very effective for suppressing intragastric acidity, but the optimal dose and duration is unknown. Current evidence indicates that pharmacologic intervention should include, at a minimum, a 3 month trial of twice daily PPI. Symptoms of LPR improve over 2 months of therapy. The physical findings of LPR resolve more slowly than the symptoms and this continues through out at least 6 months of treatment. For most patients with LPR, twice daily dosing with a PPI is usually recommended for an initial treatment for a period of no less than 6 months treatment, and lifetime treatment may be required.
Hamster에서 5-Fluorouracil로 유발한 구강점막염에 대한 Allopurinol 국소도포의 효과
주형로,노영수,최종욱,김수진 대한이비인후과학회 2002 대한이비인후과학회지 두경부외과학 Vol.45 No.12
Background and Objectives:5-Fluorouracil (5-FU) is a comonly used drug in carcinomas of the head and neck. Mucositis and bone marrow toxicity are the two major side effects. Some initial studies showed that the local use of allopurinol as a mouthwash may reduce the oral mucositis caused by the administration of 5-FU. The purposes of this study were to establish the stomatotoxicity of the chemotherapeutic agent in an animal model and to evaluate the effect of alopurinol mouthwashes in treating mucositis objectively. Materials and Method:Young male Golden Syrian hamsters were used. The combination of three intraperitoneal injection of 5-FU at five-day intervals and superficial mechanical mucosal irritation were applied and exa-three times everyday, starting with the treatment of 5-FU, only at the right buccal mucosa for one minute. Results:Light micro-scopic changes were characterized by ulcer and inflamatory cells infiltration. The scanning electron microscopic examination showed iregular microridges and pits. Gross and histopathologic alterations were reliably reduced in the allopurinol mucosal painting group. Conclusion:This study suggests an effective animal model for stomatotoxicity of chemotherapeutic agents, (Korean J Otolaryngol 2002 ;45 :1172-8)
주형로,고원혁,최동준,김일우,박일석,김범규,김용복,Chu, Hyung-Ro,Ko, Weon-Hyoug,Choi, Dong-Joon,Kim, Il-Woo,Kim, Beom-Gyu,Park, Il-Seok,Kim, Yong-Bok 대한기관식도과학회 2007 大韓氣管食道科學會誌 Vol.13 No.2
The case report of migrating ingested fish bone presenting as an unresolving inflamed neck mass is rare. The diagnosis must be suspected in a patient with an unresolving inflamed cutaneous lesion, especially one with a punctum, the tenderness of the lesion elicited on swallowing and the presence of a palpable subcutaneous neck mass. In such a patient, a history of recent foreign body ingestion must be actively sought. An accurate early diagnosis of this easily treatable condition is desirable because it could avert unnecessary delays, inconveniences, anxiety, costs, and surgery. The authors experienced a case of lateral neck mass resulting from the migration of a fish bone which was successfully removed by surgical exploration and made a report with a review of literature.