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      • SCIEKCI등재

        민속주 부재료로 이용되는 식물성 방향재료 및 약용재료중의 Asarone , Coumarin , Thujone. 의 분석

        조정옥(Jung Ok Jo),김선민(Sun Min Kim),김경수(Kyong Su Kim) 한국응용생명화학회 1999 Applied Biological Chemistry (Appl Biol Chem) Vol.42 No.3

        To detect the toxic relevant components, asarone, coumarin and thujone, in the 87 medicinal plants used in brewing a Korean traditional folk wine, their 20% ethanol extracts were prepared and purified by a SPE(solid phase extraction) method. The toxic components in the purified extracts were identified by GC-FID and GC/MS analysis. On analyses, asarone was detected in 6 species, Acorus gramineus Solander, Acorus asiaticus Nakai, Angelia gigus Nakai, Santalum album, etc.; coumarin in 22 species, Anethum graveolens, Foeniculum vulgare Gaertner, Lithosperum erythrorhizon Siebold et Zuccarinii, etc.; thujone in 24 species, Achyranthes japonica Nakai, Amomum xanthiodes Wallich, Artemisia asiatia Nakai, seed of Cannabis sativa L., Caragana sinica R., Chrysanthemum morifolium Ramat, Codonopsis lanceolata Bentham et flooker, Foeniculum vulgare Gaertner, etc.

      • KCI등재

        광나무 잎의 페놀성 화합물

        조정옥(Jeong-Ok Jo),정인창(In-Chang Jung) 한국식품영양과학회 2006 한국식품영양과학회지 Vol.35 No.6

        식물자원으로부터 생리활성 물질의 이용측면에서 국내에서 자생하고 있는 광나무 잎을 대상으로 하여 다양한 생리활성을 가지는 것으로 보고된 페놀성 화합물의 분포를 확인하였다. 총 페놀성 함량은 0.89~1.53%, 축합형 탄닌은 0.10~0.13%였으며, flavonoid는 aglycone인 apigenin, luteolin과 칼럼크로마토그라피를 행하여 분획으로 분리한 후 가수분해하여 이들의 배당체를 확인하였다. 페놀산의 분획 중 유리형 페놀산 화합물에는 tyrosol, t-cinnamic acid, p-hydroxybenzoic acid, vanillic acid, shikimic acid, protocatecuic acid 등이 존재하였다. 에스테르형 페놀산 화합물에는 tyrosol, t-cinnamic acid, ferulic acid, esculetin, caffeic acid, pcoumaric acid, hydroxytyrosol 등이 함유되었다. 결합형 페놀성 화합물에는 tyrosol, t-cinnamic, p-coumaric acid와 미확인 페놀성 물질들이 존재하였다. 따라서 광나무 잎은 xanthine oxidase 활성저해, LDL 산화, 혈소판 응집저해, 항균활성 등 다양한 생리활성을 나타내는 것으로 보고되고 있는 tyrosol, hydroxytyrosol, protocatecuic acid 등 풍부한 페놀성 화합물을 함유하고 있으므로 유용한 식물자원이 될 수 있음을 확인하였다. This study was designed to investigate the possible utilization of Ligustrum japonicum leaves as a source of functional ingredients. Contents of total phenolic compounds and condensed tannin were 0.89∼1.53% and 0.10∼0.13%, respectively. The major flavonoid compounds in the leaves of L. japonicum were luteolin, apigenin and their glycosides. Tyrosol, t-cinnamic acid, p-hydroxybenzoic acid, vanillic acid, shikimic acid and protocatecuic acid were detected in free phenolic acid, while tyrosol, t-cinnamic acid, ferulic acid, esculetin, caffeic acid, p-coumaric acid and hydroxytyrosol were detected in esterified phenolic acid. The insoluble phenolic acid contained tyrosol, t-cinnamic and p-caoumaric acid.

      • SCOPUSKCI등재

        부추(Allium tuberosum Rottler)의 휘발성 향기성분

        박은령(Eun-Ryong Park),조정옥(Jung-Ok Jo),김선민(Sun-Min Kim),이명렬(Myung-Yul Lee),김경수(Kyong Su Kim) 한국식품영양과학회 1998 한국식품영양과학회지 Vol.27 No.4

        본 연구에서는 국내에서 널리 재배되며 주로 김치의 주재료 혹은 부재료와 향신료로 이용되고 있는 부추의 향기성분을 n-pentane과 diethylether 혼합용매를 추출용매로 사용하여 휘발성 향기성분을 추출하고 이를 GC와 GC/MS를 사용하여 분석ㆍ확인하였다. 부추에서 확인된 성분은 총 65종으로, 28종의 함황화합물과 aldehyde류 12종, alcohol류 9종, lactone류와 ester류가 각각 4종, acid류와 hydrocarbon류가 각각 3종 그리고 기타 2종이 동정되었다. 동정된 성분들 중에서 함황화합물이 전체 상대농도의 73.78%로 휘발성 향기성분의 대부분을 차지하였으며, dimethyl disulfide(19.47%), dimethyl trisulfide(17.38%), trans-1-propenyl methyl disulfide, trans-2-hexenal 그리고 methylallyl disulfide가 다량 동정되어 부추의 휘발성 향기성분의 주성분으로 여겨졌다. Volatile flavor components of edible portion of leek (Allium tubercsum H.) were extracted by SDE (simultaneous steam distillation and extraction) method using the mixture of n-pentane and diethylether (1 : 1, v/v) as an extract solvent and analyzed by GC-FID and GC/MS. Identification of the volatile flavor components was mostly based on the RI of GC and mass spectrum of GC/MS. A total of sixty-five components from leek extract were classified as 28 sulfur-containing compounds, 12 aldehydes, 9 alcohols, 4 lactones and esters, 3 acids and hydrocarbons, and 2 miscellaneous compounds. The sulfur-containing compounds were predominant in leek extract. Dimethyl disulfide(19.47%) and dimethyl trisulfide(17.38%) were the main compounds and trans-1-propenyl methyl disulfide, trans-2-hexenal and methyl allyl disulfide were also detected large amounts in leek.

      • KCI등재
      • KCI등재SCOPUS
      • SCOPUSKCI등재

        고비중 Bupivacaine을 사용한 척추마취시 용적과 농도의 효과

        조정옥,안미정,손수창 대한마취과학회 1999 Korean Journal of Anesthesiology Vol.37 No.4

        Background : The purpose of this study is to investigate the effects of volume and concentration in a constant dose of subarachnoid bupivacaine on the extent and duration of sensory and motor blocks. Methods : Forty parturients scheduled for cesarean section were randomly assigned to two groups for spinal anesthesia. In group 1, 3.5 ml of hyperbaric 0.25% bupivacaine (8.75 mg) with 0.25 mg morphine and 10 μg fentanyl were injected into the subarachnoid space; in group 2, 1.75 ml of hyperbaric 0.5% bupivacaine (8.75 mg) with 0.25 mg morphine and 10 μg fentanyl were injected. Dural punctures were performed at the L3-L4 or L2-L3 interspaces with a 25 gauge needle in the sitting position after which the patients were turned to the supine horizontal position. The level and extent of the sensory and motor block were measured at 3, 5, 10, and 15 minutes. The onset, duration and regression of sensory and motor blocks were studied. Results : There were no significant differences between two groups in the level d extent of sensory and motor blocks. From onset time to maximal sensory block took 12.1 ± 3.0 min in group 1, and 13.3 ± 3.7 min in group 2, and from onset time to complete motor block took 10.2 ± 2.7 min in group 1 and 11.4 ±2.6 min in group 2. There was no significant difference in the time taken to complete the regression of seosory block, and the complete resolution of the motor block. Conclusions: A constant 8.75 mg dose of subarachnoid hyperbaric bupivacaine produced, in all groups, a similar, statistically insisnificant, level and extent of sensory and motor block, in spite of different volumes and concentrations. (Korean J Anesthesiol 1999; 37: 603∼607)

      • KCI등재

        녹황색 채소류 중의 카로티노이드 함량과 Blanching 에 의한 변화

        정인창,조정옥 한국조리과학회 2000 한국식품조리과학회지 Vol.16 No.1

        시판 녹황색 채소를 대상으로 하여 생것과 3% 끓는 소금물에 데치기한 후의 카로티노이드 색소 함량을 HPLC를 이용하여 분석한 결과는 다음과 같다. 카로티노이드 색소인 α-carotene, β-carotene 그리고 lutein을 각각 분석한 결과 5가지 채소 모두에서 lutein과 β-carotene이 검출되었고 α-carotene은 당근에서만 검출되었다. 또한 lutein은 미나리에서, β-carotene은 부추에서 가장 많은 함량 증가가 있었다. 실험에 사용한 시료 모두에서, 카로티노이드 색소의 구성 성분에는 변화가 없었으나 생것과 비교하였을 때 데친것에서 함량 증가가 나타났다. 이러한 결과로 미루어 보아 채소류는 끓는 3% 소금물에 살짝 데친 후에 섭취하는 것이 카로티노이드 색소의 이용 측면에서 유용하다고 생각된다. Carotenoids in commercial green-yellow vegetables(carrot, mugwort, perilla leaf, leek and water dropwort) were analyzed by HPLC. Carotenoids detected were lutein, α-carotene, and β-carotene. β-Carotene and lutein were detected in every sample analyzed, but α-carotene could only be detected in carrot. Blanching vegetables in 3% saline increased the content of carotenoids, however, the components of carotenoids were not changed. This result suggests that blanching increases the amount of available carotenoids.

      • SCOPUSKCI등재

        심한 대동맥 협착증 산모에서 응급 제왕절개술을 위한 전신마취 경험

        조정옥,안미정,이윤이,손수창,양예영 대한마취과학회 1999 Korean Journal of Anesthesiology Vol.37 No.5

        A 34-year-old female underwent emergency cesarean section with general anesthesia. The patient was a para 1-0-0-1, referred at 39 weeks in labor with known severe aortic stenosis due to a bicuspid aortic valve. She has been treated with digoxin and furosemide for 5 years. At first, she tried a normal spontaneous vaginal delivery, but dyspnea was aggravated during delivery, so an emergency operation was decided. Anesthesia was induced using ketamine 80 mg, fentanyl 50 μg and vecuronium 6 mg and maintained with 50% nitrous oxide in oxygen. After fetal delivery and infusion of oxytocin, the systolic blood pressure decreased to 60 mmHg or less, so we injected phenylephrine 100 μg bolus. However, the blood pressure did not increase, so we injected phenylephrine continuously ( 0.5 μg/kg/ min). One month postpartum, echocardiography was done. The left ventricle-aortic pressure gradient was 140 mmHg, so the cardiologist recommended an aortic valve replacement operation. She refused the operation and has been medied with digoxin and furosemide up to date. (Korean J Anesthesiol 1999; 37: 951∼954)

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