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치매의 임상적 정도와 인지기능 장애 및 행동 장애간의 상관
조성완,박종한 대한신경정신의학회 1994 신경정신의학 Vol.33 No.3
The point prevalence of TD as assessed by Abnormal Involuntary Movement Scale (AIMS) was determined for chronic wards with 361 schizophrenic patients(194 male, 167 female) (mean age 37.3 ± 10.4) at the time of the study. The results were as follows : 1) When T D was defined as those with a rating 3 or higher for any one or more than one of seven body items, the prevalence rate was 17.0% in 194male schizophrenics, 22.8% in female and mean 19.7%. 2) Among the risk factors, age was statistically significant relationship with the occurrence of TD and there was no significant relationship between the occurrence of TD and there was no significant relationship between the occurrence of TD and sex, the use of antiparkinsonian agent, history of electroconvulsive therapy and dosage of antipsychotics at the examination. 3) TD of the orofacial region was positively associated with age and history of ECT, while TD of non-orofacial (trunk and extremities) regions were not related. Our findings suggest that prevalence of TD in the schizophrenics was positively associated with age, and TD of the orofacial and non-orofacial regions may be distinct clinical syndromes, each having a different set of etiological determinants.
조성완,김상곤,홍기민,심승보,조명래,조성운,박윤 한국물리학회 2017 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.71 No.10
Measurement of reflected optical light from the surface of microscopic structures can offer a precise tool to investigate the oscillatory motion of micro- and nano-mechanical resonators. We demonstrate an optical investigation of multiple flexural modes of a nanomechanical resonator in thermal motion based on amplitude-modulated laser light, with higher-order resonant modes up to 17 MHz measured with this technique. Scanning focused laser light reproduces the mode shape of each flexural mode, and theoretical estimation of measurement sensitivity shows a displacement sensitivity of 10−15 m/Hz1/2. For nanomechanical devices incompatible with interferometric systems, this technique can exhibit sufficient sensitivity to explore small motional states.
조성완,윤명오,공하성 한국화재소방학회 2009 한국화재소방학회논문지 Vol.23 No.6
Disaster Management should be re-established and developed based on voluntary participations of individuals and groups, not only as a concern of the government. This paper proposes about improvement methods of managing volunteers for disaster management as follows: First, a necessity for publicity and recruitment focused on selfish motive to emphasize individual’s development, selfrealization, worth and economic interesting relationship in a process of recruitment and selection, Second, a construction of process to commonly develop education program to volunteers for disaster management, Third, an activity area of volunteers for disaster management is enlarged to the intrinsic task of disaster management, Forth, an evaluation of quality for volunteer activity and compensation. 재난관리는 정부만의 관심사가 아닌 개인과 단체의 자발적 참여를 기반으로 재정립되고 발전시켜야 할 것이다. 본 논문은 재난관리 자원봉사자 관리의 개선방안으로 첫째, 모집과 선발과정에서 개인의 발전이나 자아실현, 보람 및 경제적 이해관계 등을 강조하는 이기적 동기에 중점을 둔 홍보와 모집정책 필요 둘째, 재난관리 자원봉사자들에 대한 교육프로그램을 공통으로 개발할 수 있는 프로세스의 구축 셋째, 재난관리 자원봉사자의 활동 영역을 재난관리의 본질적 업무까지 확대 넷째, 자원봉사활동의 품질평가와 보상 등을 제시하였다.
새로운 약물 송달 촉진제에 의한 경구용 인슐린의 흡수 향상 연구
조성완,임성혁,정지훈 중앙대학교 의과대학 의학연구소 2005 中央醫大誌 Vol.30 No.3·4
The aim of this study was to evaluate new oral insulin preparation using newly developed drug absorbtion enhancer(Procarrier). Rats was divided into two groups, one of them was normal control and the other was diabetic disease model. Each group was administered with insulin or insulin/Procarrier solution and then we measured serum insulin level and blood glucose level using radio immunoassay and glucomerter, respectively. Insulin/Procarrier significantly enhanced the oral absorbtion of insulin compraed to insulin. Moreover, Insulin/Procarrier effectively decreased blood glucose level in diabetic disease model. These results suggest that Insulin/Procarrier may be effective in the treatment of diabetic mellitus via the increase in the oral absorbtion of insulin. In contrast, Insulin/Procarrier did not affect blood glucose level in normal control with stable blood glucose level after Insulin/Procarrier administration. This finding indicate that there may be little risk of hypoglycemia with Insulin/Procarrier. The hypoglycemia is the most common adverse effect of oral insulin preparations. In conclusion, Insulin/Procarrier with economic cost and convenience in use might lead to new drug delivery system of oral insulin or other peptide drugs.