유상피 육종의 흡인 세포학 - 1예 보고 -

조경자,김정연,이승숙,강신광,Cho, Kyung-Ja,Kim, Jung-Youn,Lee, Seung-Sook,Khang, Shin-Kwang 대한세포병리학회 1996 대한세포병리학회지 Vol.7 No.1

Cytologic features of the fine needle aspiration of metastatic epithelioid sarcoma are presented. The patient was a 48 year-old male who had been sufferring from recurrent and metastatic tumors of the right upper extremity for 6 years. The aspirate from the axillary mass cytologically consisted of isolated large polygonal cells with abundant, cyanophilic, slightly granular cytoplasm. Eccentrically located large round nuclei showed finely dispersed chromatin, small nucleoli, occasional convolution and folding of nuclear membrane, and frequent binucleation. Although both histologic and cytologic similarity of epithelioid sarcoma to squamous cell carcinoma is well known, findings of cyanophilic granular cytoplasm, convoluted nuclei, and binucleation appeared to be the differential points.

자극의 주체와 움직임의 유형이 지향성 탐지에 미치는 영향

조경자,김혜리,시은경 한국심리학회 산하 한국발달심리학회 2006 한국심리학회지 발달 Vol.19 No.2

Intentional detection is defined as when people detect an object which moves toward special direction as an agent having a goal and desire to go there. This study examined whether people detect the motions of self-propelled objects like human silhouettes and the motions of nonself-propelled objects like geometrical shapes or flowers as intentional agents when they interpret their movements. This study also, examined whether people detect and interpret motions differently when they see different motions, non-meaningful motions, goal-directed motions and interacting motions between two objects. The results demonstrate that people have tendency to detect the motions of human silhouettes more intentionally than the motions of geometrical shapes and flowers, and detect the interacting motions more intentionally than non-meaningful motions and goal-directed motions. Especially when the motions of human silhouettes were presented, people detect and interpret them as fully intended motions even when non-meaningful motions and goal-directed motions were presented. However when presented with nonself-propelled objects, geometrical shapes and flowers combined with interactive movements, people demonstrated a strong tendency to interpret their movements more intentionally than the other motions. This study suggests that people detect and interpret different agent's motions and motions of objects differently. 지향성 탐지란 사람들이 특정 방향으로 움직이고 있는 자극을 그 방향으로 가려고 하는 목적과 바람을 가진 행위자(agent)로 해석하는 것이다. 본 연구에서는 사람들이 자극의 움직임을 탐지할 때, 스스로 움직임을 유발하는 사람자극만을 지향적으로 해석하는지, 아니면 특정방향으로 움직이는 모든 자극의 움직임(기하학적 도형, 꽃, 사람 자극)을 지향적인 것으로 이해하는지를 알아보았다. 또한 특별한 의미를 부여하기 힘든 움직임, 목표지향적인 움직임, 두 자극들 간에 상호작용하는 움직임에 따라 지향적으로 해석하는 정도가 달라지는지 알아보았다. 실험 결과 사람들은 삼각형과 꽃 자극보다는 사람 자극의 움직임에서 지향적으로 판단하는 경향이 강했으며, 무의미한 움직임과 목표지향적인 움직임 보다는 상호작용하는 움직임을 더 지향적인 것으로 판단했다. 또한 행위자가 스스로 움직임을 유발하는 사람일 경우에는 모든 움직임을 지향적으로 해석하였다. 그러나 스스로 움직일 수 없는 자극인 기하학적인 도형과 꽃 자극에서는 다른 움직임에 비해 상호작용 움직임을 보일 때 지향적으로 해석하는 경향이 강했다. 본 연구 결과는 자극의 주체와 움직임 유형에 따라 지향성 탐지 정도가 달라진다는 것을 시사한다.

사람 Low Density Lipoprotein (LDL)에 대한 Rooibos tea의 항산화 활성

조경자,김희숙,박종옥,류병호 경성대학교 2001 論文集 Vol.22 No.1

This study was investigated to antioxidative activity of crude catechin extracted from Rooibos tea against low density lipoprotein(LDL) oxidation. The crude catechin inhibited the copper-mediated oxidation of human LDL at the concentrations of 50 and 100 ㎍/㎖ in the presence of 5 μM CuSO4. The crude catechin also inhibited LDL oxidation induced by macrophage J774 cell. LDL oxidized by copper mediated and cell induced oxidation was degraded by macrophage at a much greater rate than native LDL. The electrophoretic mobility of oxidized LDL by addition of crude catechin was faster than that of native LDL. The results provided a possibility that crude catechin of Rooibos tea might protect LDL against oxidation in atheroscleotic lessions.

건강생활 영역의 교수-학습지도 및 평가의 실제

조경자 국립특수교육원 2004 자격연수 Vol.- No.6

폐암의 새로운 종양표식자 CYFRA 21-1

조경자,이경혜,이중원,송경은,이원길,김재식,박재용 대한임상병리학회 1997 대한임상병리학회지 Vol.17 No.1

보행과 에너지소비

조경자 大韓再活醫學會 1979 Annals of Rehabilitation Medicine Vol.3 No.1

Basaloid Squamous Cell Carcinoma of the Head and Neck: Subclassification into Basal, Ductal, and Mixed Subtypes Based on Comparison of Clinico-pathologic Features and Expression of p53, Cyclin D1, Epidermal Growth Factor Receptor, p16, and Human Papillom

조경자,정세운,김성배,이상욱,최승호,남순열,김상윤 대한병리학회 2017 Journal of Pathology and Translational Medicine Vol.51 No.4

Background: Basaloid squamous cell carcinoma (BSCC) is a rare variant of squamous cell carcinoma with distinct pathologic characteristics. The histogenesis of BSCC is not fully understood, and the cancer has been suggested to originate from a totipotent primitive cell in the basal cell layer of the surface epithelium or in the proximal duct of secretory glands. Methods: Twenty-six cases of head and neck BSCC from Asan Medical Center, Seoul, Korea, reported during a 14-year-period were subclassified into basal, ductal, and mixed subtypes according to the expression of basal (cytokeratin [CK] 5/6, p63) or ductal markers (CK7, CK8/18). The cases were also subject to immunohistochemical study for CK19, p53, cyclin D1, epidermal growth factor receptor (EGFR), and p16 and to in situ hybridization for human papillomavirus (HPV), and the results were clinico-pathologically compared. Results: Mixed subtype (12 cases) was the most common, and these cases showed hypopharyngeal predilection, older age, and higher expression of CK19, p53, and EGFR than other subtypes. The basal subtype (nine cases) showed frequent comedo-necrosis and high expression of cyclin D1. The ductal subtype (five cases) showed the lowest expression of p53, cyclin D1, and EGFR. A small number of p16- and/or HPV-positive cases were not restricted to one subtype. BSCC was the cause of death in 19 patients, and the average follow-up period for all patients was 79.5 months. Overall survival among the three subtypes was not significantly different. Conclusions: The results of this study suggest a heterogeneous pathogenesis of head and neck BSCC. Each subtype showed variable histology and immunoprofiles, although the clinical implication of heterogeneity was not determined in this study.

유방의 세침 흡인 세포학

조경자,고재수,하창원,장자준,Cho, Kyung-Ja,Koh, Jae-Soo,Ha, Chang-Won,Jang, Ja-June 대한세포병리학회 1992 대한세포병리학회지 Vol.3 No.2

A number of studies have shown the value of fine needle aspiration cytology for the diagnosis of breast lesions, but reports on the comparison of cytologic and histologic variations of breast cancers are few. We reviewed histologically proven 106 breast aspirates with an emphasis on the cytology of ductal carcinomas and of an area of uncertain atypia. Positive and negative predictive values of breast aspiration cytology were 100% On review of the cases originally diagnosed as atypia of uncertain nature (19 %), features more suggestive of malignancy or benignancy were recognizable in most underdiagnosed cases and a half of overdiagnosed cases, respectively. However, indistinguishable atypism also remained. Thirty seven cases out of 53 infiltrating duct carcinomas revealed malignant cytology, with variations in background, cellularity, morphology of cell groups, and extent of isolated tumor cells. When classifying the infiltrating duct carcinomas into scirrhous, solid-tubular, and papillotubular types, scirrhous type frequently appeared as irregularly shaped tight or loose cell clusters, and solid-tubular type as round-margined cell balls.

유방 관내암종의 병리

조경자 대한외과학회 1999 대한외과학회 학술대회 초록집 Vol.1999 No.5

예비유아교사의 놀이 은유에 나타난 놀이에 대한 인식

조경자,이현숙 한국교원대학교 교육연구원 2012 敎員敎育 Vol.28 No.4

본 연구의 목적은 유아교사교육의 초기 과정에 있는 예비유아교사들이 지닌 유아의 놀이에 대한 인식을 알아보기 위한 것이다. 이를 위해 유아교육 전공 대학생 1학년 108명에게 유아에게 놀이가 의미하는 바를 은유로 표현하도록 하고 그 이유를 서술하도록 하였다. 분석 결과, 예비유아교사들이 기술한 유아의 놀이에 대한 은유적 표현은 총 81가지였으며 이들 표현은 ‘식물’, ‘동물’, ‘자연’, ‘사람’, ‘활동’, ‘추상’, ‘음식’, ‘물건’, ‘장소’ 등 9개 범주로 분류되었다. 가장 많이 나타난 범주는 ‘물건’이었으며, 다음은 ‘자연’, ‘사람’이었다. 은유적 표현에 나타난 놀이에 대한 인식은 ‘성장과 발달’, ‘즐거움’, ‘학습’, ‘자발성’, ‘탐색’, ‘생활 자체’, 그리고 ‘정서적 치유’의 7개의 범주였다. 가장 빈번하게 나타난 범주는 ‘성장과 발달’, ‘즐거움’, ‘학습’이었다. 이러한 결과는 예비유아교사들이 교사교육과정의 초기부터 놀이를 가치 있고 교육적인 것으로 여기고 있음을 나타내는 것이다. The purpose of this study was to examine preservice early childhood teachers' perceptions of play through metaphors they described. The participants of this study were 108 freshmen from the department of early childhood education at a three-year college. The journals about the metaphors of children's play and the reason for their metaphors were analyzed. Preservice teachers used 81 metaphors to describe on children's play. Metaphors were classified into 9 categories: plants, animals, nature, persons, activities, abstracts, foods, materials, places. The most frequently used metaphors were the categories of the materials, natures, and persons. The perceptions of play reflected in the metaphors were categorized into 7 themes: growth and development, learning, joy, spontaniety, exploration, child's life itself, and mental recovery. Among these, growth and development, joy, and learning were the most frequently mentioned to describe the metaphors of play. These results indicate that even before they took the course on children's play, preservice early childhood teachers regard children's play as invaluable and educational.