http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
신봉경,이영석,정회선,이상호,김현철,김애리,김인선,김한겸,Shin, Bong-Kyung,Lee, Young-Suk,Jeong, Hoi-Seon,Lee, Sang-Ho,Kim, Hyun-Chul,Kim, A-Ree,Kim, In-Sun,Kim, Han-Kyeom The Korean Society for Cytopathology 2008 대한세포병리학회지 Vol.19 No.2
Urothelial carcinoma accounts for 90% of all the cases of bladder cancer. Although many cases can be easily managed by local excision, urothelial carcinoma rather frequently recurs, tends to progress to muscle invasion, and requires regular follow-ups. Urine cytology is a main approach for the follow-up of bladder tumors. It is noninvasive, but it has low sensitivity of around 50% with using the conventional cytospin preparation. Liquid-based cytology (LBC) has been developed as a replacement for the conventional technique. We compared the cytomorphometric parameters of $ThinPrep^{(R)}$ and cytospin preparation urine cytology to see whether there are definite differences between the two methods and which technique allows malignant cells to be more effectively discriminated from benign cells. The nuclear-to-cytoplasmic ratio value, as measured by digital image analysis, was efficient for differentiating malignant and benign urothelial cells, and this was irrespective of the preparation method and the tumor grade. Neither the $ThinPrep^{(R)}$ nor the conventional preparation cytology was definitely superior for distinguishing malignant cells from benign cells by cytomorphometric analysis of the adequately preserved cells. However, the $ThinPrep^{(R)}$ preparation showed significant advantages when considering the better preservation and cellularity with a clear background.
강시묵 ( Si Mook Kang ),정회인 ( Hoi In Jung ),정승화 ( Seung Hwa Jeong ),권호근 ( Ho Keun Kwon ),김백일 ( Baek Il Kim ) 대한예방치과·구강보건학회 2010 大韓口腔保健學會誌 Vol.34 No.1
Objectives. The aim of this study was to develop a new caries activity test based on colorimetric changes that could better reflect the amount of acid produced by oral bacteria as a broad spectrum of color than the previous test. The optimal candidates were combinations of pH indicators, and these were evaluated in pH buffering solutions and using dental plaque. Methods. Six pH indicators, Bromocresol-purple (BCP), Bromocresol-green (BCG), Methyl-red (MR), Methyl-orange (MO), Resazurin (R), and Naphthyl-red (NR), were selected to show different colors at various pH environments (range pH 3.0~7.0). BCP and BCG are pH indicators that are already used in the Cariostat(R), and they can show color changes from blue to yellow. This study tried to broaden the color change spectrum from blue to red to give a more distinct differentiation at various pHs. Four pH indicators (MR, MO, R and NR) were blended with BCP and BCG. Each combination of the three indicators was assessed in different pH buffer systems: pH 7.0, 6.0, 5.0, 4.0, and 3.0. The selected combinations of pH indicators were applied to human dental plaque from 11 subjects (mean age: 27) to confirm the reproducibility of the in vitro results. Results. According to the in vitro buffer system, the mixture of BCP, BCG and MR did not show any differences between pH 4.0 and pH 3.0. On the other hand, the mixtures of BCP-BCG-MO (ratio 2:1:1.5), BCP-BCG-R (1.5:1:0.5) and BCP-BCG-NR (2:1:1.5) showed distinguishable color changes from pH 7.0 to pH 3.0. Among the three candidates, the BCP-BCG-NR mixture showed the best color differences in the buffer solution and the human dental plaque cultivated solutions at various pHs. Conclusions. This study evaluated a new colorimetric caries activity test that used a combination of several pH indicators. The new system can easily detect various pH environments from organic acid fermentation by using a wider range of colors (blue-dark green-green-orange-red).