덤벨체조가 농촌지역 여성 고령자의 신체조성, 생활체력 및 인지기능에 미치는 영향

이기철 ( Ki Chul Lee ),정창주 ( Chang Joo Jeong ),손기수 ( Ki Su Son ),권은진 ( Eun Jin Kwon ),신재후 ( Jae Hoo Shin ),전수경 ( Soo Kyoung Jeon ),우임수 ( Im Soo Woo ),이원경 ( Won Gyeong Yi ) 한국운동영양학회 2004 Physical Activity and Nutrition (Phys Act Nutr) Vol.8 No.2

The present study evaluated the possibility of dumbbell exercise as to improve the health status of elderly women in rural area. Although approximatly 300 volunteers of elderly women living in rural area of Gumi city were subjected, 32 of them were attended the whole training program for 6 months. All examine were operated before training. 3 months and 6 months after starting point of training respectively. The items of measurement and their results were as the following, 1. The blood pressure slightly increased after 3 months, and blood sugar level significantly decreased after 3 months and then slightly increased. 2. The self living ability not significant changes but slightly increased, that means positive effect of dumbbell exercise on self living ability in their old age. 3. The cognitive ability, Mini-Mental State Examination (MMSE) Korean version questionnaire were used, slightly increased. 4. All items of the physical fitness except masticate strength were increased, that means positive effect of dumbbell exercise on physical activity level in elderly people. Therefore all items level was better than before dumbbell exercise, including blood sugar level, cognitive ability, physical fitness. That assumed dumbbell exercise help elderly people` both physical and mental ability.

지유가 흰쥐의 급성위염 및 소화성 궤양에 미치는 영향

이재준(Jae Joon Lee),최현숙(Hyun Suk Choi),이정화(Jeong Hwa Lee),정창주(Chang Joo Jung),이명렬(Myung Yul Lee) 한국식품영양과학회 2005 한국식품영양과학회지 Vol.34 No.10

본 실험에서 흰쥐에 실험적으로 급성위염, 위궤양 및 십이0지장궤양을 유발하고 지유 에틸아세테이트분획을 투여하여 항위염 및 항궤양에 미치는 영향을 검토하였던 바 다음과 같은 결과를 얻었다. 지유 에탄올 추출물을 n-헥산, 클로르포룸, 에틸아세테이트 및 n-부타놀과 물로 계통분획하여 농축하고 in vitro에서 항산화력을 측정한 결과 에틸아세테이트분획이 가장 우수하였다. 지유 에틸아세테이트분획(SOL & SOH)의 HCl-EtOH급성위염에 대한 억제율은 각각 27.7%, 31.7%로 대조약물로 사용된 cimetidine(CMT, 47.2%)의 억제효과에는 미치지 못했으나 CON에 비해 우수하였다. Indomethacin유발 위궤양에서, SOL & SOH의 위궤양억제율은 각각 48.28%, 51.08%로 대조약물로 사용된 CMT(58.26%)의 억제효과에는 미치지 못했으나 CON에 비하여 유의성 있는 억제효과를 나타냈다. Shay 위궤양에서, 지유 에틸아세테이트분획을 십이지장에서 위내로 투여하였을 때 궤양 억제율은 SOL이 42.86%로 CON에 비하여 억제되었으나 유의성있는 효과는 아니었으며, 용량을 증량하여 투여한 SOH는 47.71%로 대조약물인 omeprazol(OMP)의 저해효과(62.00%)에 미치지는 못했으나 CON에 비해 유의적인 효과를 나타내었다. 위액량 및 총위산분비량에서, 지유 에틸아세테이트분획 투여로 CON에 비하여 32.11%와 47,69%, 24.28%와 34.69%의 감소로 유의성있는 효과를 나타냈으며 OMP(55.69%, 41.62%)에 근접하게 감소되었다. Pepsin 활성은 지유 에틸아세테이트분획 투여로 CON에 비해 각각 19.55%, 21.45%가 저하되었으나 유의성있는 변화는 아니었다. 수침ㆍ구속 스트레스에 의해 유발된 궤양의 경우, SOL는 궤양억제율이 9.23%로 CON와 유사하게 출혈을 동반한 깊은 궤양이 관찰되었으나 용량을 증량하여 투여한 SOH는 48.45%로 CON에 비해 궤양의 깊이도 얕아졌고 출혈을 동반한 궤양도 감소되어 유의적인 억제율을 나타내었다. Cysteamine 유발 십이지장궤양에서, CMT는 유발된 십이지장 궤양을 CON에 비해 54%정도 억제하여 우수한 항궤양효과를 나타냈고 시료투여군인 SOL 및 SOH는 CMT보다 우수하지는 않았으나 약 35~42%정도의 궤양억제율을 나타냈다. 이상의 실험결과에서 지유의 항위염 및 항궤양효과는 항산화물질에 의한 결과로 판단되어지며, 앞으로 위염 및 위궤양 개선을 위한 건강 기능성 식품으로 개발이 기대된다. Sanguisorba officinalis L. has been used as a traditional remedy for arthritis, neuralgia, diarrhea, vomiting, gastric ulcer and gastro-intestinal disorders. This study was performed to investigate the protective effects of ethylacetate fraction of Sanguisorba officinalis L. ethanol extract (SOE) on the gastric mucosal damage and gastric ulcer induced by HCl-ethanol, indomethacin, Shay-ligation method, restraint and water-immersion stress, and cysteamine in rats. The experiment animals were divided into four groups: a negative control group (CON), positive control group (cimetidine 100 ㎎/㎏-CMT or omeprazol 100 ㎎/㎏ administrated group-OMT), SOE 200 ㎎/㎏ administrated group (SOL) and SOE 400 ㎎/㎏ administrated group (SOH), respectively. Rats were given an oral or intraduodenal administration of SOE, and all SOE treatment groups compared with the CON significantly inhibited HCl-ethanol-induced acute gastritis and indomethacin-induced gastric ulcers in dose-dependent manner, of which effects were lower in a positive control drug (CMT). The inhibition rates (%) on the acute gastritis induced by HCl-ethanol and the gastric ulcers induced by indomethacin in rats, 17.66% and 48.28% in SOL, 21.71%, and 51.08% in SOH, and 47.26% and 58.26% in CMT compared with CON, respectively. In pylorus ligated rats, the groups of SOE showed decreases in the volume of gastric secretion and acid output. However, no significant differences were observed in the pepsin activity between treated groups. In addition, SOH also depressed gastric ulcers induced by restraint and water-immersion stress and duodenal ulcers induced by cysteamine. These results suggest that Sanguisorba officinalis L. has remarkable antigastric ulcer effects and could be developed as a new antigastric ulcer agents.

女高生들의 建康에 關한 調査 硏究 : 高 3學年을 中心으로

鄭昌柱 慶北大學校 師範大學 體育學硏究會 1986 體育學會誌 Vol.14 No.-

This study conducted to evaluate the health status of 1,200 students of three girls' high schools in Daegu city and Cornel Medical Index was applied to the data gathered form May 1 to 31, 1985. The results were as follows; 1. Complaint level of each grade. In comparison with the general complaint state, the mumber of physical complaints from 3 grade was higher than that of 1 grade, and was revealed as a significant difference (p<0.001). The number of mental complaints from 3 grade was higher than that of 1 grade, and was revealed as a significant difference (p<0.05). In the item analysis, items: V_1, V_2, V_3, V_5, V_6, V_10, V_11, V_14 Scored higher among 3 grade. 2. Complaint level among each one's school credits record. In terms of the general complaint status, physical complaints among superior group were higher than those among inferior group (p<0.001). In terms of V_1, V_2, V_3, V_5, V_6 items, physical or mental complaints among superior group are higher than those among inferior group. and in terms of V_13, inferior group were higher.

C.M.I에 의한 中學校 運動選手의 心身健康評價

鄭昌柱 慶北大學校 師範大學 體育學硏究會 1985 體育學會誌 Vol.13 No.-

This study was conducted to get the precise information about the physical and mental complaints among middle school athletes in order to build up and develop the health status and physical strength. Eight hurdred athletes composing of each 200 male and female athletes and each 200 boy and girl student were randomly sampled, and the Cornell Medical Index was applied to the data gathered from July through August, 1984. The results are as follows: 1. Complaint level of middle school students in accordance with sex. In comparison with the general complaint state, the number of physical or mental complaints from female was higher than that of male, and was revealed as a significant difference(p<0.001). In the item analysis, items V_4, V_5, V_6, V_8, V_9, V_10, V_11, V_12, V_14 scored higher among female-athletes. 2. Complaint, rate of male athletes about team game and person-to-person game; Physical complaints among person-to-person athletes were higher than those among team game athletes(p<0.05). In terms of V_4, V_5, V_11, V_13 items, physical complaints among person-to-person athletes were higher than those among team athletes, and in terms of V_10, V_12, team game athletes were higher. 3. Complaint rate among athlete group and student group Physical complaints among student group were higher than those among male athletes(p<0.01), mental Complaints among student group were also higher than those among male athletes(p<0.001), Female athletes case was also the same(p<0.01). In the item analysis, items V_2, V_3, V_6, V_9, V_10, V_11, V_12, V_13, V_14 scored higher among male student group and the items V_2, V_9, V_10, V_11, V_12 scored higher among female student group and the items V_4, V_6 scored higher among female athlete group.

東醫 스포츠 醫學에 關한 小考

鄭昌柱 慶北大學校 師範大學 體育學硏究會 1991 體育學會誌 Vol.19 No.-

Through reviewing of the principles and therapeutic modalities of oriental medicine, it is possible to improve the physical condition and health of the people through exercise therapy of oriental medicine with little facilities and expenses. Exercise therapy of oriental medicine may be helpful to athletes engeged in sports which need highly concentration of attention, such as Shooting Archery, Gymnastics, Diving, Sprinting, also to athletes engaged in sports which need momentary power such as Weight lifting, Judo, Ssireum, Boxing. Moreover this modality is effective in prevention of disease, concentration of sttention, keeping balance between body and mind. Acupuncture in oriental medicine may be used not only to cure injuries of athletes but to relieve the anxiety. Medical therapy in oriental medicine can contribute to improvement of stamina and performance of athletes by developing sports drinks. Massage in manual manipulation can prevent and treat sports injuries and decrease acute fatigue caused by exessive training and hard matches, so it is effective in improvement of performance. There are few doctors and athletic leaders specialized in oriental sports medicine and progression of studies in this field is little at present. Therefore oriental sports medicine should be studied and developed furthermore with close relation of western medicine. It is mandatory ot develop oriental sports medicine through scientific, objective and systematic method with introduction of statistics, experimental and clinical studies of western style.

햄스터 구강암 발생 과정에서 Heat Shock Protein에 관한 면역조직화학적 연구

최규환,이동근,김은철,정창주 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.2

A IMMUNOHISTOCHEMICAL STUDY ON HEAT SHOCK PROTEIN IN ORAL CARCINOGENESIS IN HAMSTER Heat shock protein (HSP) expression is unto·emulated in tumor cells and, HSP expression is likely marker of the malignant potential of oral epithelial lesion. Furthermore, the 70kDa HSP is implicated in the degree of tumor differentiation, the rate of tumor proliferation and the magnitude of the anti-tumor Immune response. Accordingly, the distribution and intensity of HSP70 and HSP47 expression was assessed in the DMBA induced oral carcinogenesis in hamster. Golden Syrian hamsters which were 3 months-age and 90∼120g were collected. 9,10-dimethyl -1,2-ben-zanthracene (DMBA) in a 0.5% solution in mineral oil was painted on the buccal pouch mucosa 3 times per week in the study group. In each control and experimental groups of 6, 8, 10, 12, 14, 16, 18, 20 weeks, specined for immunohistochemical study with anti-HSP47 and anti-HSP70 antibody. The following results were obtained. 1.HSP47 positive cells were race or negative of normal oral mucosa, increased mildly in basal and suprabasal basal layer, and spinous cell layer after experimental 6 weeks (dysplastic or CIS stage). In CIS stage, HSP47 expression is prominent in dysplastic free or normal adjacent epithelium. 2.HSP47 positive cells in connective tissue were mainly inflammatory cells, which is gradually increased from control to precancerous and cancer stage. But HSP47 positive cells after 14 weeks were decreased, especially normal and cancer adjacent epithelium. 3.The positive staining cells of HSP70 in control, dysplastic, and CIS stage were not seen. But they were mild findings in basal layer and moderate findings in spinous layer after experimental 14 weeks (cancer stage). 4.HSP70 positive cells were increased in precancerous and cancer stage than control group in connective tissue. After experimental 16 weeks, we could not find the HSP expression in cancer cells according to cancer differentiation or cancer stage. It is concluded that HSP70 or HSP47 expression is not a definitive marker of oral malignancy or malignant potential. However, with further development, HSP immunoreactivity may be valuable as an adjunct to conventional histology for assessing the malignant potential of oral mucosal lesions.

고등학교 유도선수들의 주관절(elbow)에 대한 등속성 근력 분석

최동욱,정창주 대한스포츠의학회 1998 대한스포츠의학회지 Vol.16 No.2

Since isokinetic exercise equipment can give an evaluation of muscle strength with great accuracy and objectivity, it is more widely using as the one of the important methods in sports and rehabilitation medicine. The purpose of this study was to evaluate strength values for elbow flexion and extension at 60°, 180°, 240°/sec using the isokinetic rahabilitation and testing system (Model No. Cybex 340) on 20 high school Judo players comprising 10 high level palyers (Group 1 and 10 normal playrers(Group 2). The results ware follows ; 1. The peak torque %body weight of flexion and extension at 240°/sec was higher in Group 1 than Group 2(P<0.05). 2. There was no significant difference between Group 1 and Group 2 in the angle of peak torque output. 3. No significant difference between two groups was found in flexion to extension peak torque ratio. 4. The average power in flexion at 240°/sec was higher in Group 1 than Group 2(P<0.05) and the endurance ratios in flexion and extension were higher in Group 1 than Group 2 (P<0.05), but there was no significant difference in the total work between two groups.