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      • KCI등재

        소아의 결장에서 발생한 원발성 선암종 1예

        정재열,서유경,김애숙,이선주,조성민,이동석,김두권,최성민,김동훈,Jung, Jae-Youl,Seo, Yu-Koyng,Kim, Ae-Suk,Lee, Sun-Ju,Cho, Sung-Min,Lee, Dong-Seok,Kim, Doo-Kwun,Choi, Sung-Min,Kim, Dong-Hoon 대한소아소화기영양학회 2007 Pediatric gastroenterology, hepatology & nutrition Vol.10 No.1

        소아와 청소년기에 발생하는 대장의 악성 종양은 매우 드물고 예후가 불량하다. 저자들은 내원 3개월 전부터의 식욕 부진, 체중 증가 지연과 내원 6일 전부터의 설사, 복통, 복부 종괴 촉지를 주소로 내원한 12세 남아에서 복부 초음파 촬영, 복부 전산화 단층 촬영, 바륨대장 조영술, 대장 내시경 검사 및 조직 검사 소견으로 진단된 S상 결장에 발생한 점액 선암종 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Colorectal carcinomas occur primarily in elderly people and are rare in children. Unlike adult colorectal carcinomas, the overall prognosis is very poor because of the usual delay in diagnosis and advanced stages at presentation or initial diagnosis, and a high incidence of aggressive tumor pathology such as mucinous adenocarcinoma. Colon cancer should not be excluded in children only based on age or barium enema results. Therefore, colonoscopy should be performed in pediatric patients with unexplained rectal bleeding and abdominal pain. We report a rare case of a child with a mucinous adenocarcinoma of the sigmoid colon in a 12-year-old boy, who presented with an abdominal mass and abdominal pain and review the medical literature.

      • KCI등재

        흡입독성 연구를 위한 2730ppm 납 네뷸라이징 용액에서 발생된 에어로졸의 입경분석

        정재열,강성호,김삼태,이은경,송용선,이기남 대한동의생리학회,대한동의병리학회 2003 동의생리병리학회지 Vol.17 No.2

        Ultrasonic nebulizer with the application of new engineering methodology and the design of electronic circuit was made for lead inhalation toxicology study and 2730ppm lead nebulizing solution was used to generate lead aerosol. After modification of source and inlet temperatures, the results of particle size analysis for lead aerosol were as following. The highest particle counting for source temperature 20˚c was 39933.66 in inlet temperature 100˚C and particle diameter 0.75㎛. The highest particle counting for source temperature 50˚C was 39992.71 in inlet temperature 250˚C and particle diameter 0.75㎛. The highest particle counting for source temperature 70˚C was 37569.55 in inlet temperature 50˚C and particle diameter 0.75㎛. The ranges of geometric mean diameter(GMD) were 0.754-0.784㎛ for source temperature 20˚C, 0.758-0.852㎛ for source temperature 50˚C, and 0.869-1.060㎛ for source temperature 70˚C. The smallest GMD was 0.754㎛ in source temperature 20˚C and inlet temperature 20˚C, and the largest GMD was 1.060㎛ in source temperature 70˚C and inlet temperature 250˚C. The ranges of geometric standard deviation(GSD) were 1.730-1.782 for source temperature 20˚c, 1.734-1.894 for source temperature 50˚C, and 1.921-2.148 for source temperature 70˚C. The lowest GSD was 1.730 in source temperature 20˚c and inlet temperature 20˚C, and the highest GSD was 2.148 in source temperature 70˚C and inlet temperature 250˚C. Lead aerosol generated in this study was polydisperse. The ranges of mass median diameter(MMD) were 1.856-2.133㎛ for source temperature 20˚C, 1.877-2.894㎛ for source temperature 50˚C, and 3.120-6.1091m for source temperature 70˚C. The smallest MMD was 1.856㎛ in source temperature 20˚C and inlet temperature 20˚C, and the largest MMD was 6.109㎛ in source temperature 70˚C and inlet temperature 250˚C. Slight increases for GMD, GSD, and MMD values were observed with same source temperature and increase of inlet temperature. MMD for inhalation toxicology testing in EPA guidance is less than 4㎛. In this study, source temperature 20˚C and 50˚C with inlet temperature from 20˚C to 250˚C were conformed to the EPA guidance, but inlet temperature 20˚C and 50˚C for source temperature 70˚C were conformed EPA guidance. MMD for inhalation toxicology testing in OECD and EU is less than 3,um. In this study, source temperature 20˚C and 50˚C with inlet temperature from 20˚C to 250˚C were conformed to the EPA guidance, but none for source temperature 70˚C.

      • KCI등재

        메타버스 환경에서 홍채인식와 안구 주위 생체인식을 결합한 지속적 인증 기법 분석

        정재열,노건태 사단법인 한국융합기술연구학회 2023 아시아태평양융합연구교류논문지 Vol.9 No.10

        코로나19 이후에 비대면 서비스가 증가함에 따라 메타버스에 대한 관심이 증가하고 있으며, VR 기기를 이용하여 메타버스에 접속하는 기술들이 개발되고 있다. 이에 메타버스의 보안에 대한 중요성이 대두되고 있으며 메타버스에서는 인증 한 번으로 서비스를 계속 이용하기 때문에 사용자 인증이 중요한 보안 이슈 중 하나이다. 홍채 인증은 인증에 가장 적합한 방법으로 사용자의 홍채의 특징을 바탕으로 데이터를 판단하고 홍채의 조그만 변화도 큰 차이를 만들며 VR 기기에 홍채 카메라를 탑재하면 홍채 이미지를 얻기 쉽다. 따라서 인증을 한 번만 할 경우에 홍채를 이용한 인증이 적합하다. 하지만 보안을 위해서 지속적으로 인증을 하기 위해서는 홍채 인증만으로는 부족하다. 왜냐하면 지속적 인증을 위해 홍채 이미지를 주기적으로 생성하는 데 눈을 항상 올바르게 뜨고 있기 어렵기 때문이다. 홍채 이미지 생성할 때 노이즈가 포함될 확률이 높으며 그러면 인증의 정확도가 떨어지게 된다. 이때 안구 주위 인증이 필요하다. 안구 주위 인증은 원거리에서 획득이 가능하기 때문에 인식 대상자의 협력에 대한 제약이 적고, 헬멧, 마스크 등으로 얼굴의 일부 영역이 가려진 상태에서도 획득이 가능한 장점이 있다. 따라서 본 논문에서는 홍채와 안구 주위 정보를 이용한 지속적인 다중 생체인증 기법을 제안하였다. 그리고 관련 연구들의 실험 결과를 통해서 제안하는 기법의 활용 가능성을 보여주었다. With the increase in untactable services due to COVID-19, interest in the metaverse is growing, leading to the development of technologies to access it through VR devices. Accordingly, the importance of the security of metaverse is rising, and user authentication is one of the most important security concerns because metaverse continues to use the service with only one authentication. Iris authentication is the most suitable method for authentication because data is measured based on the unique characteristics of the user's iris. Small changes in the iris result in significant differentiation, and if an iris camera is attached to a VR device, obtaining an iris image becomes effortless. Therefore, when authentication needs to be performed only once, iris authentication is appropriate. However, iris authentication alone is insufficient for continuous security authentication. This is because it is difficult to keep your eyes open at all times to periodically generate iris images for continuous authentication. There is a high probability that noise is present when generating an iris image, which can affect the accuracy of authentication. At this time, periocular certification is required. Certification around the eye can be obtained from a long distance, with few restrictions on the cooperation of recognition subjects, even when some areas of the face are covered by helmets and masks. Therefore, this paper proposes a technique for continuous authentication using multiple biometrics, including iris and periocular biometric information. And the potential for utilization is shown through the experimental results from related studies.

      • KCI등재

        동(銅) 취투(取投) 작업장(作業場) 공기중(空氣中) 동(銅) 농도(濃度)와 생물학적폭로지수(生物學的暴露指數)

        정재열,김정만,김두희,Jeung, Jae Yeal,Kim, Jung Man,Kim, Doo Hie 한국산업보건학회 1993 한국산업보건학회지 Vol.3 No.1

        구리 분진에 과다 폭로되는 작업자를 조기 발견하고 생물학적 폭로지수를 제시하고자, 폭로군으로 야금 작업장에서 62명의 담성 작업자를 선정하였다. 구리에 폭로되는 작업자의 개인폭로농도를 평가하기 위해 개인, 공기 시표표집방법을 이용했다. 폭로군에서 생물학적 폭로는 원자흡광광도계를 이용하여 혈액과 요중의 구리농도로 평가하였다. 대조군으로는 직업적으로 구리에 폭로된 기왕력이 없는 성인 남성 70명을 선정하였다. 폭로군의 혈액에서 구리의 평균 농도는 $49.44{\pm}8.90{\mu}g/dl$이었고, 요에서 구리의 평균농도는 $39.99{\pm}11.04{\mu}g/l$이었다. 공기중 구리의 평균농도는 $0.48{\pm}0.31mg/m^3$이었다. 대조군의 혈액에서 구리의 평균농도는$42.93{\pm}5.84{\mu}g/dl$이었고, 요에서 구리의 평균농도는$33.02{\pm}13.38{\mu}g/dl$이었다. 폭로군과 대조군의 혈중 및 요중 구리의 평균농도사이에는 모두 유의한 차이가 있었다. 양군에서 연령과 혈중 구리 농도 및 요중 구리의 농도 사이에는 모두 상관관계가 없었다. 폭로군의 혈중 구리와 요중 구리의 농도사이에는 상관관계가 있었고(r=0.62), 대조군의 혈중 구리농도와 요중 구리의 농도사이에는 상관관계가 있었다(r=0.39). 근속연수에 따른 혈중 및 요중 구리의 평균농도사이에는 모두 유의한 차이가 없었으며, 근속연수와 혈중 및 요중 구리농도사이에는 모두 상관관계가 없었다. 작업공정에 다른 공기중 구리평균농도사이에는 유의한 차이가 있었으나, 혈중 및 요중 구려평균농도사이에는 유의한 차이가 있었으며, 공기중 구리의 개인폭로농도와 혈중 구리농도 및 요중 구리농도 사이에는 모두 상관관계가 있었다(혈중 구리, r=0.54 요중 구리, r=0.37). This study was designed obtain and early detection the workers exposed to excessive copper dust and also to present biological exposure index. The exposed group consisted of 62 male workers at the metallurgy workplaces. To evaluate the degree of individual exposure the copper dust, each personal air sampling was collected. Biological exposures in the exposed group was quantified for the blood and urine copper levels using flameless atomic absorption spectrophotometer. The control group consisted of 70 male adults with the history of nonexposure to copper by the inhalation occupationally. The average concentration of copper in blood and urine of the exposed group was $49.44{\pm}8.90(29.05-80.63){\mu}g/dl$, $39.99{\pm}11.04(29.62-80.63){\mu}g/l$ respectively. The average concentration of air borne copper was $0.48{\pm}0.31(0.03-1.18)mg/m^3$. The average concentration of blood and urine copper in the control group was $42.93{\pm}5.84(25.05-57.85){\mu}g/dl$, $33.02{\pm}13.38(12.00-82.05){\mu}g/l$ respectively. The difference observed in the average concentration of blood and urine copper of the exposed and control groups was statistically significant seperately (blood copper, p<0.05 ; urine copper, p<0.05). The relationship between the individual exposure concentration of air borne copper and the concentration of the blood and urine copper was statistically significant, respectively (blood copper, r=0.54, p<0.05 ; urine copper, r=0.37, p<0.05). The relationship between the working duration and the concentration of blood and urine was not statistically significant respectively (blood copper, r=0.14 ; urine copper, r=0.12). The relationship between the age and the concentration of blood and urine copper was statistically not significant respectively (blood copper, r=013 ; urine copper, r=-0.06). The relationship between blood and urine copper concentration in the exposed group was statistically significant (r=0.62, p<0.05), and the relationship between blood and urine copper concentration in the control group was also statistically significant (r=0.39, p<0.05).

      • KCI등재

        Environment-vulnerability evaluation of a high-speed railway line in Korea using a groundwater-anomaly method

        정재열,함세영,장성,황학수,문상호 한국지질과학협의회 2019 Geosciences Journal Vol.23 No.3

        The Republic of Korea completed the first phase of the Honam high-speed railway from Seoul to Gwangju in 2014, and the second phase from Gwangju to Mokpo will be completed in 2025. This study evaluates the vulnerability of the groundwater environment in the Cheonan-Iksan zone, which passes through three preliminary lines (the Cheonan-Daejeon-Iksan line, Cheonan-Gongju-Iksan line, and Cheonan-Osong-Iksan line) of the Honam high-speed railway, to determine the most suitable line. The groundwater-level anomaly is evaluated along the three lines of the high-speed railway. The depth to water ranged from 0.03 to 21.1 m and from 0.17 to 227.95 m (AMSL). To determine a suitable line for the high-speed railway, a groundwater-level anomaly (GLA) grade is used, which considers the spatial distributions of the depth to water and groundwater elevation. Based on the GLA evaluation index, the Cheonan-Daejeon-Iksan (CDI) line exhibited the highest vulnerability (85.39), while the Cheonan-Osong-Iksan (COI) line had the lowest vulnerability (47.41). Vulnerable geological engineering, which is indicated by a discharge-estimation (DE) grade higher than 4, occurred in a section of the CDI line with a DE grade of 9, suggesting that attention should be directed to the discharge of groundwater during tunnel excavation.

      • KCI등재

        桑葉 Ethyl Acetate 추출물이 카드뮴의 흡입독성에 미치는 영향

        정재열,송용선,이기남 대한동의병리학회 2003 동의생리병리학회지 Vol.17 No.3

        For the experiment of the effects between cadmium aerosol inhalation toxicity and ethyl acetate extracts of Folium Mori, 4 inhalation exposure groups of rat were exposed to cadmium aerosol in air by whole-body inhalation exposure for 6 hours/day, 5 days/week, and 4 weeks. Cadmium concentration in the air was 0.96㎎/㎥ and mass median diameter (MMD) was 2.48㎛ with 1.85 of geometric standard deviation(GSD). Intraperitoneal injections of ethyl acetate extracts of Folium Mori to inhalation exposure groups were performed for 4 weeks and the results were as follows: The highest body weight gain for 4 weeks and food intake per day were 159.29/4 weeks in treated group Ⅲ and 18.45g/day in treated group Ⅰ, respectively. The highest lung and liver weight were 1.31g in treated group Ⅰ and 9.42g in treated group Ⅲ, respectively. The highest kidney weight was 2.21g from treated group Ⅰ. The lowest cadmium content in lung was 86.39㎍/g from treated group Ⅲ and the lowest cadmium concentration in blood was 2.72㎍/㎗ from treated group Ⅱ. Cadmium concentrations of 22.09㎍/g in liver and 24.82㎍/g in kidney were the lowest from inhalation exposure group Ⅰ and Ⅲ, respectively. For weekly cadmium concentration in urine, the value of the fourth week from treated group Ⅲ was the highest, 1.35㎍/㎖. For weekly cadmium concentration in feces, the values of the second and fourth week from treated group Ⅰ were the highest, 1.11㎍/g. The highest metallothionein concentration in lung was 31.85㎍/g from treated group Ⅲ and the highest metallothionein concentration in liver was 205.77㎍/g from treated group Ⅲ. The highest metallothionein concentration in kidney was 206.55㎍/g from treated group Ⅲ. The highest Hct and Hb values were 38.26% and 11.63g/㎗ from treated group Ⅲ, respectively. The highest RBC and WBC values were 7.68×106/㎣ and 9.85×10^3/㎣ from treated group Ⅰ, respectively.

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