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제2형 당뇨병환자에서 혈중 글루카곤 농도와 심혈관 질환 위험도의 관계
정우석,문재철,유소연,Jeong, Wooseok,Moon, Jaecheol,Yoo, Soyeon 제주대학교 의과학연구소 2020 The Journal of Medicine and Life Science Vol.17 No.2
Glucagon regulates glucose and fat metabolism as well as being involved in the production of ketone bodies. The new antidiabetic drug, a sodium-glucose co-transporter-2 inhibitor, increases glucagon, and reduces the risk of cardiovascular death and hospitalization due to heart failure. The presence of metabolic syndrome is an important risk factor for cardiovascular diseases(CVD) in type 2 diabetes(T2DM) patients. We, thus, investigated the association between glucagon levels and metabolic syndrome in T2DM patients. This cross-sectional study involved 317 T2DM patients. Fasting and postprandial (30 min after ingestion of a standard mixed meal) glucagon levels were measured. Metabolic syndrome was defined according to the criteria of the International Diabetes Federation. A multiple regression logistic analysis was employed for statistical evaluation. A total of 219 (69%) subjects had metabolic syndrome. The fasting and postprandial glucagon levels did not differ between the group with metabolic syndrome and the group without. Postprandial glucagon levels increased significantly with the increase in the number of metabolic syndrome components, but the fasting levels did not. However, a hierarchical logistic regression analysis revealed that the postprandial glucagon levels did not contribute significantly to metabolic syndrome even after adjusting for other covariates. Fasting and postprandial glucagon levels are not associated with metabolic syndrome in T2DM patients. However, further studies are needed to investigate the relationship between glucagon and cardiovascular risk in patients with T2DM.
진드기 백신 개발을 위한 기초연구(I) - 수용성 항원에 대한 면역반응에 관하여 -
정우석,강승원,최은진,윤용덕,Jeong, Woo-seog,Kang, Seung-won,Choi, Eun-jin,Yoon, Yong-dhuk 대한수의학회 1996 大韓獸醫學會誌 Vol.36 No.3
Haemaphysalis longiscornis is the common cattle tick of great economic importance in Korea. Chemical control using dips or sprays has been the traditional method of attempting to kill these ticks during the infestation period. However, the presence of resistant forms to chemical, the rising costs of acaricides and environmental problems have made it almost impossible to use these chemicals on a regular basis according to the pest problem. For this reason, vaccination against ticks and breeding for host resistance against ticks are being studied. In order to determine the common proteins and antigens according to developmental stages, SDS-PAGE and western blotting were performed. In SDS-PAGE 103.3kD and 98.3kD proteins were observed as common proteins, and these proteins were observed as common antigens in western blotting. Unimmunized rabbits were infestated three times with H longicornis. The weight of the second and the third engorged ticks were 0.153g and 0.104g respectively. This weight is 69% and 47% of the first engorged ticks weight respectively. Immunized rabbits by adult ticks antigen and control were infested with H longicornis. The control taked 3-4 days to fully engorge, but the immunized rabbits taked about 7 days. So adult tick antigen may be effective to render the immunity to host.
농지은행 경영회생지원사업 농지환매권에 대한 실물옵션가치 추정-충북지역을 중심으로-
정우석 ( U Seok Jeong ),서상택 ( Sangtaek Seo ) 한국축산경영학회 2014 농업경영정책연구 Vol.41 No.1
Among the dobt policies are business recovery program provided by Farmland Bank. Farmers with the program are given the redemptive right for the farmland during the program period of seven years. Thus farmers need to make a decision when to exercise the redemptive right. A real options with binomial distribution approach is adopted for this purpose. Farmlands includeonly paddy field in Chungbuk province to exclude the possibility of speculative transaction. Results show that an early exercise with convenience yield(CY) can take place, but not with net convenience yield(NCY). In addition, optimal exercise with NCY is made at the maturity of seven years. Americano ption value is greater than European option value when CY is involved. On the other hand, both values are the same under NCY consideration because exercise is only made at the maturity in both cases. Sensitivity analysis shows that option value is increasing with interest rate, volatility of farmland price, and loan rate but decreasing with deposit rate. The results imply that farmers need to exercise the redemptive right optimally by observing the flow of farmland price. And development of supporting system for farmers` decision making and consulting activities are required.
정우석(Useok Jeong),김종우(Jongwoo Kim),송대섭(Dae-Seob Song),조규진(Kyu-Jin Cho) 대한기계학회 2013 대한기계학회 춘추학술대회 Vol.2013 No.12
This study focuses on the design and evaluation of control algorithm that is embedded on cycle ergometer for rehabilitation. The admittance control algorithm is developed for the safe, compliant and effective rehabilitation exercise. The control mode is consist of passive and active mode depending on how the user exerts force. The intensity of the exercise can be adjusted by changing the impedance parameter of the controller. A developed algorithm is tested on the cycle ergometer which is widely used for the rehabilitation of upper limb and lower limb. The results show that admittance control scheme can flexibly guide the limbs compared to speed or position control and can provide various intensity of exercise with several combination of the impedance parameters.
논벼 무경운재배의 온실가스 감축효과를 고려한 경제성 분석
정우석(U Seok Jeong),김성섭(Seong sup Kim),서상택(Sang taek Seo),김숙진(Sook jin Kim) 한국농식품정책학회 2017 농업경영정책연구 Vol.44 No.4
This study performed an economic analysis for no-till practice of paddy rice compared with traditional till practice of paddy rice. The effect of reducing greenhouse gas (GHG) emissions from soil and agricultural machinery was added to economic outcome of no-till practice. Experimental data of GHG and yield by practices were obtained from National Institute of Crop Science and partial budgeting method was adopted for the analysis. Results showed that GHG reduction from no-till practice was very large in soil compared with agricultural machinery. The economic outcome of no-till practice was larger than that of traditional till practice even when it did not contain GHG reduction effect. In addition, no-till practice showed positive economic performance regardless of the ownership for agricultural machinery. The results of this study are expected to be highly useful as legitimacy of policy support for no-till paddy rice practice.