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정난이,변혜진,박재현,김준식,김해원,하지용 대한소아청소년과학회 2018 Clinical and Experimental Pediatrics (CEP) Vol.61 No.1
Purpose: The aim of this study was to evaluate the diagnostic accuracy of urinary biomarkers, such as neutrophil gelatinase-associated lipocalin (uNGAL) and β-2 microglobulin (uB2MG), in early detection of urinary tract infection (UTI) in infants aged <3 months with fever. Methods: A total of 422 infants aged <3 months (male:female=267:155; mean age, 56.4 days), who were admitted for fever, were retrospectively included in this study. We compared uNGAL and uB2MG between the UTI and non-UTI groups at the time of admission. The sensitivity, specificity, accuracy, and area under the curve (AUC) of uNGAL and uB2MG for use in diagnosing UTI were assessed. Results: Among 422 patients, 102 (24.2%) were diagnosed with UTI. Levels of uNGAL were higher in the UTI group than in the non-UTI group (366.6 ng/mL vs. 26.9 ng/mL, P<0.001). Levels of uB2MG were not different between the 2 groups. Multivariate analysis revealed that uNGAL was an independent predictive factor for UTI (P=0.033). The sensitivity, specificity, and accuracy were 90.2%, 92.5%, and 91.9% for uNGAL, and 48.0%, 43.8%, and 44.8% for uB2MG, respectively. AUC of uNGAL was 0.942 and that of uB2MG was 0.407. Conclusion: Accuracy of uNGAL in the diagnosis of UTI is high in febrile infants aged <3 months. uNGAL can help in the early diagnosis and treatment of UTI in infants.
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유아교사의 자기효능감과 셀프리더십이 교수몰입에 미치는 영향
정난이,차정주 한국교원대학교 유아교육연구소 2022 한국유아교육연구 Vol.24 No.2
The purpose of this study is to examine the effects of self-efficacy and self-leadership on commitment to teaching among early childhood teachers as to provide basic data for determining specific measures to improve teaching commitment. 203 early childhood teachers from 133 kindergartens and 70 daycare centers respectively who have worked in the Daegu and Gyeongbuk regions took a survey for this study, and the collected data was analyzed using SPSS 26.0. The results of the study found that there was significant positive correlation among all three factors of self-efficacy, self-leadership, and teaching commitment. Moreover, self-efficacy and self-leadership displayed statistically significant effect on teaching commitment. The results of this study suggest that opportunities to develop self-efficacy and self-leadership are required in tandem with efforts to improve self-efficacy and self-leadership directly. 본 연구는 유아교사의 교수몰입을 향상할 구체적인 방안을 마련하기 위한 기초자료를 제공하고자유아교사의 자기효능감과 셀프리더십이 교수몰입에 미치는 영향을 탐색하고자 하였다. 대구, 경북 지역에소재한 유치원과 어린이집에 근무 중인 교사 203명(유치원 133명, 어린이집 70명)을 대상으로 설문조사를실시하였으며, 수집된 자료를 SPSS 26.0을 사용하여 분석하였다. 본 연구의 결과는 다음과 같다. 첫째, 유아교사의 자기효능감, 셀프리더십, 교수몰입 간에는 모두 유의미한 정적 상관관계가 있는 것으로 나타났다. 둘째, 유아교사의 자기효능감, 셀프리더십은 모두 교수몰입에 정적인 영향을 미치는 것으로 나타났다. 본연구의 결과는 유아교사의 교수몰입을 향상하기 위해서는 자기효능감, 셀프리더십을 기를 수 있는 다양한교육의 기회가 제공되어야 함과 동시에 유아교사 스스로 자기효능감과 셀프리더십을 향상할 수 있는 노력이필요함을 시사한다.
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신주희,이동현,정난이,최희정,최희정 대한혈액학회 2018 Blood Research Vol.53 No.3
Background Reactive thrombocytosis (RT) is a common condition among children, although no stud-ies have examined the etiology or clinical characteristics of RT among Korean children. Methods This retrospective study evaluated children with RT at a single Korean tertiary center dur-ing a 10-year period. Results RT accounted for 13.5% of children who were admitted to the pediatric ward (4,113/30,355): mild RT, 82.7%; moderate RT, 14.1%; severe RT, 1.1%; and extreme RT, 2.1%. There was a negative correlation between platelet count and Hb level (P=0.008). There were positive correlations between platelet count and WBC (P=0.001), eryth-rocyte sedimentation rate (ESR) (P=0.007), and admission duration (P=0.006). The most common cause of RT was infection and the second most common was Kawasaki disease (KD). The highest proportion of lower respiratory tract infection was observed in extreme RT (P<0.001). The proportion of KD was highest in extreme RT (P<0.001) and in children aged 1‒7.9 years (P<0.001). The proportion of refractory KD was highest in extreme RT (P=0.005). In cases of KD, there was a positive correlation between platelet count and fever duration (P=0.006). Non-KD autoimmune inflammation was only observed in mild/moderate RT, and its proportion was highest in children aged 8‒18 years (P<0.001). ConclusionIn children, more severe RT was associated with lower Hb, increased WBC, ESR, and pro-longed admission. With respiratory infection or KD, extreme RT was associated with more severe disease course.
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신주희,이동현,정난이,최희정,최희정 대한혈액학회 2018 Blood Research Vol.53 No.3
Background Reactive thrombocytosis (RT) is a common condition among children, although no stud-ies have examined the etiology or clinical characteristics of RT among Korean children. Methods This retrospective study evaluated children with RT at a single Korean tertiary center dur-ing a 10-year period. Results RT accounted for 13.5% of children who were admitted to the pediatric ward (4,113/30,355): mild RT, 82.7%; moderate RT, 14.1%; severe RT, 1.1%; and extreme RT, 2.1%. There was a negative correlation between platelet count and Hb level (P=0.008). There were positive correlations between platelet count and WBC (P=0.001), eryth-rocyte sedimentation rate (ESR) (P=0.007), and admission duration (P=0.006). The most common cause of RT was infection and the second most common was Kawasaki disease (KD). The highest proportion of lower respiratory tract infection was observed in extreme RT (P<0.001). The proportion of KD was highest in extreme RT (P<0.001) and in children aged 1‒7.9 years (P<0.001). The proportion of refractory KD was highest in extreme RT (P=0.005). In cases of KD, there was a positive correlation between platelet count and fever duration (P=0.006). Non-KD autoimmune inflammation was only observed in mild/moderate RT, and its proportion was highest in children aged 8‒18 years (P<0.001). ConclusionIn children, more severe RT was associated with lower Hb, increased WBC, ESR, and pro-longed admission. With respiratory infection or KD, extreme RT was associated with more severe disease course.
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A Case of Jacobsen Syndrome Presenting with a Huge Cephalhematoma and Thrombocytopenia after Birth
신주희,김가은,이로지,정난이,심예지,하정숙 대한소아혈액종양학회 2018 Clinical Pediatric Hematology-Oncology Vol.25 No.1
Jacobsen syndrome (JS) is a contiguous gene syndrome resulting from a deletion of chromosome 11q, with various clinical manifestations. A post-term small for gestational age infant was born by normal vaginal delivery without trauma or vacuum extraction. On day 5, right parietotemporal scalp swelling developed, with petechiae on the right cheek and thrombocytopenia (platelets: 63,000/mL). A prominent forehead, wide-set eyes, short and upturned nose were noted. Karyotyping and microarray analysis demonstrated del(11)(q24q25), consistent with Jacobsen syndrome. Brain magnetic resonance imaging (MRI) revealed a huge cephalhematoma. The patient is scheduled to receive periodic evaluations for thrombocytopenia and heart, kidney, abdominal malformations, ophthalmologic and auditory problems. There are lots of newborns with cephalhematoma or petechiae after birth. Not all newborns with these symptoms need evaluations, but if they have these symptoms with suspect features or appearances, we need to go through further evaluations.
KCI
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