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      • KCI우수등재

        가축의 유전적 개량을 위한 지시형질의 이용에 관한 연구 - 젖소를 중심으로 -

        이광전(K . J . Lee),정길생(K . S . Jung),한상기(S . K . Han),박홍양(H . Y . Park),양영목(Y . M . Yang),박경도(K . D . Park),박동준(D . J . Park) 한국축산학회 1991 한국축산학회지 Vol.33 No.11

        This study was carried out with bull calves of high and low breeding value for milk yield, using a pedigree index. At the same time, plasma concentrations of several traits were investigated in order to find out the potential use of indicator traits for the genetic improvement. Results obtained from this study are as follows. 1. Total protein contents of plasma showed significant differences between genetic groups during feeding(P$lt; 0.05), while albumin contents were significantly different during refeeding (P$lt;0.01). Phenotypic correlation between pedigree index and total protein was -0.2111 and this result indicates that further research ias needed for the potential use of indicator traits. 2. Cholesterol concentraions of plasma showed significant differences between genetic groups only during the feeding period, and the content of bull calves with high breeding value was higher than that of lower bull calves. 3. Mean concentrations of glucose were not significantly different between genetic groups of three treatments, while fasting caused a reduction in glucose concentration which increased upon refeeding. 4. Correlation between pedigree index and blood urea nitrogen was -0.0478 and no potential use of indicator traits was found. 5. Concentrations of triglyceride with the high breeding group were lower than those of the low yielding group, and the reversal trend was observed upon refeeding. 6. Phenotypic correlation between total protein and globulin was 0.69. while genetic correlation between cholesterol and triglyceride showed the highest value of 0.97. 7. Heritability and intraclass correlation of cholesterol were estimated as 0.224 and 0.229, respectively. Coheritability of blood urea nitrogen was calculated as -0.03. There was no indication of the potential use of indicator traits.

      • SCOPUSKCI등재

        원형정자세포의 주입에 의한 임신과 분만 1례

        이상민,정지영,한용태,박해택,박흠대,정길생,이기영,Lee, S.M.,Jung, J.Y.,Han, Y.T.,Park, H.T.,Park, H.D.,Chung, K.S.,Lee, K.Y. 대한생식의학회 1998 Clinical and Experimental Reproductive Medicine Vol.25 No.2

        We demonstrated that the normal pregnancy and delivery by round spermatid injection (ROSI) into oocytes was achieved from nonobstructive azoospermia patient. In this case, the normal fertilization rate was 50%. All of the two pronuclear stage embryos cleaved and were transferred to the patient's uterus. A singleton pregnancy was achieved and resulted in the birth of normal female infant. This resuJt show that intracytoplasraic injection of round spermatid seems to be new treatment of nonobstmctive azoospermia male infertility. Further research is needed to evaluate the required culture conditions to induce progression of the round spermatid into a more elongated stage.

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