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치과용 수복재의 수분흡수도와 압축강도의 변화에 관한 연구
장우혁,최영철,Chang, Woo-Hyuck,Choi, Yeong-Chul 대한소아치과학회 2003 大韓小兒齒科學會誌 Vol.30 No.1
레진계열의 심미성 수복재는 구성성분에 따라 각기 다른 특성과 물리적 성질을 나타낼 뿐만 아니라, 수복물 주변의 환경도 물성에 많은 영향을 미친다. 특히 수분의 흡수는 수복재 물성 변화에 큰 역할을 하며, 재료의 조성과 친수성 정도, 경화기전, 침지기간과 배지 등의 다양한 요소와 관련되어 수복재마다 각기 다른 양상을 나타낸다. 본 연구의 목적은 임상에서 많이 이용되고 있는 레진계열의 수복물 중에서 복합레진, 레진변형 글라스아이오노머 및 콤포머의 침지기간에 따른 수분흡수도와 압축강도의 변화를 계측하여 비교하고, 수분흡수도와 압축강도 간에 나타나는 상관관계를 밝히고자함이다. 복합레진으로는 Z-100(3M, U.S.A.), 콤포머는 F-2000(3M, U.S.A.), 레진변형 글라스아이오노머는 Vitremer Restorative(3M, U.S.A.)를 이용하여 수분흡수도와 압축강도 측정을 위한 시편을 각각 제작하였다. 각 시편을 1일, 2주, 4주, 8주간 $37^{\circ}C$ 증류수에 넣어 보관한 후 수분흡수도는 침지 전과 후의 질량차를 부피로 나눈 값으로 산출하고, 압축강도는 Instron(Instron Corporation Headquarters, U.S.A.)을 이용하여 측정한 후 다음과 같은 결과를 얻었다. 1. 세 가지 수복재 모두 침지기간이 길어짐에 따라 수분흡수도가 증가하였으며 수분흡수의 대부분은 초기 2주 동안에 나타났다(P<0.001). 2. 레진변형 글라스아이오노머의 수분흡수도가 복합레진과 콤포머에 비해 상대적으로 크게 나타났다. 3. 세 가지 수복재 모두 침지시간에 따라 압축강도가 감소하였으며(복합레진과 콤포머: P<0.001, 레진변형 글라스아이오노머: P<0.05), 특히 복합레진이 다른 재료에 비해 가장 큰 감소 경향을 나타냈다. 4. 세 가지 수복재 모두 수분흡수도가 증가함에 따라 압축강도가 감소하였다(P<0.05). The aesthetic restorative materials are widely used in recent dentistry, showed not only the different quality between each component but also showed that the environment of the material has important effect on the physical properties of the material. Especially, when the restoratives are restored in the mouth, and since saliva is existing, the restoratives are always exposed to water and affected by the saliva. The purpose of this study was to research and compare the change of the degree of water sorption after water immersion of three types of the resin-based materials and the compressive strength, and observe the relation between the change of the water absorbing degree and the compressive strength. Z-100(3M, U.S.A) as a composite resin, F-2000(3M, U.S.A) as a compomer and Vitremer Restoratives(3M, U.S.A) as a resin-modified GIC were used, and each specimen was made to measure the water sorption and to evaluate the compressive strength. The specimens for measurement of the water sorption and the compressive strength were divided into 4 groups(1 day, 2 weeks, 4 weeks, and 8weeks). Each specimen was filled in the 30cc vial with 20cc of distilled water during the fixed amount of period in $37^{\circ}C$. The water sorption is decided by dividing the difference of weight before and after the immersion by the volume, and the compressive strength was measured by using the instron after the immersion. The following results were obtained ; 1. The more the water sorption increased, the more the immersion period of three restorative materials was long. And the most of water sorption was obtained during the first 2 weeks(P<0.001). 2. The water sorption of resin-modified GIC was higher than composite resin and compomer. 3. The more the compressive strength decreased, the more the immersion period of three restorative materials increased(composite resin and compomer: P<0.001, resin-modified GIC: P<0.05). Especially, the amount of the reduction in compressive strength of the composite resin was the highest. 4. The more the water sorption of all materials increased, the more the compressive strength decreased(P<0.05).
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NRBC검사에 었어서 XE-2100과 Manual N-RBC Count의 비교
장우혁 ( Woo Hyuck Chang ),김천희 ( Chun Hee Kim ),조병철 ( Byeng Chul Cho ),지현숙 ( Hyun Sook Chi ) 대한임상검사과학회 2000 대한임상검사과학회지(KJCLS) Vol.32 No.3
Background : π1e presence of NRBC is normal for frrst several days in newbom. π1e presence of NRBC in the peripheral blood in adu1t is not associated with a specific single c1inical diagnosis, but in other situations the appearance of NRBC indicates disordered erythropoiesis. In many cases, NRBC in peripheral blood is an important marker of significant hematological and non-hematological diseases. NRBC should therefore be identified precisely Most automated hematology analyzers have a flagging system to indicate the presence of NRBC in a sample qua1itatively. πus makes it necessary to correct the WBC count by substrating the number of NRBC according to manual microscopy. But, manual microscopic examination has low sensitivity, specificity, and reproducibi1ity. Method Peripheral blood specimens anticoagulatεd with EDTA wεrε studiεd. 100 samples were analysed on XE-2100 and manual NRBC count. Result Manual microscopic reference NRBC counts of 10 patient specimens showed good correlation with XE-2100 (y= 1.2692x - 0.4722 ; r = 0.9354). But, the manual microscopic NRBC result counted 100 cells indicates low correlation (y=0.7787x + 7.6241 ; r = 0.8640). Performance for with-in day precison showed a mean coefficient of variation (CV) for the XE-2100 of = 5.4% (2.0-8.4%), with a mean CV for manual NRBC counts of 22.1 %. The between day precision using QC material (SF-CHECK), was 2.94% for low control 1.29% for normal control, and 1.63% for hlgh control. Conclusion : We conc1ude that thls automated method using XE-2100 was suitable for accurate NRBC counting in peripheral blood specimens with improved performance in terms of accuracy, reproducibi1ity, and sensitivity when compared to manual microscopic methods.
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장우혁,이긍호,최영철 大韓小兒齒科學會 2002 大韓小兒齒科學會誌 Vol.29 No.2
Lowe 증후군 또는 안뇌신증후군(oculocerebrorenal syndrome)은 X-염색체와 관련된 유전성 질환으로, 반성열성유전양상을 나타낸다. 선천성 백내장과 녹내장 등의 증상, 근긴장 저하, 건반사감소 등의 근신경계 증상, 신장 기능이상이 가장 특징적인 임상증상이며, 이외에도 정신 지체, 성장지연, 전두부 융기, 가늘고 성긴 모발, 돌출된 귀, 골질환 등이 발생할 수 있다. Lowe증후군 환자는 정신지체로 인해 치과치료시 전신마취하에서의 처치가 요구되나, 대사성 산증, 악성고열의 발생위험과 사용약제의 의한 부작용 등이 위험요소로 작용할 수 있으므로, 필요한 경우 내과 또는 소아과 의료진이 참여된 협진체제 하에서 가능한 짧은 시간 진행되어야 한다. 이러한 치과적 처치의 어려움으로 Lowe증후군 환자에서 치과질환의 예방이 좀더 강조되어야 하며, 이를 위해 보호자의 주위의 적극적 관리가 요구된다. Lowe syndrome, also known as oculocerebrorenal syndrome, is a rare genetic disorder involving eyes, kidney and nervous system, and occurs predominantly in mostly males. The patients with Lowe syndrome are charac-terized with prominent forehead, thin and sparse hair, protruding ears, congenital cataracts, glaucoma, mental retardation, stunted growth, hypotonia, decrease in muscle mass and tendon reflexes, renal tubular dysfunction, and metabolic bone disease. A 6-year-old boy with Lowe syndrome was admitted to our clinic, with multiple caries and a chief complaint of intermittent pain on the left mandibular molar area. Because of difficulty in management of behavior and his medical problem, general anesthesia was performed for dental care. No specific complication was noticed during dental treatment procedure under general anesthesia and also during periodic recall-checks. General anesthesia itself, however, could be a potentially life-threatening procedure due to patient's biomed-ical problems. When a dental procedure under general anesthesia is to required in patient with Lowe syn-drome, it may be advisable being teamed with physicians, and general anesthesia duration should be as short as possible.
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