항공산업의 육성방향

장기중,Jang, Gi-Jung 재료연구소 1990 機械와 材料 Vol.2 No.4

신경제계획에 따른 기계산업의 발전방향

장기중,Jang, Gi-Jung 재료연구소 1993 機械와 材料 Vol.5 No.2

노년기 주관적 기억력 감퇴와 인지기능의 연관성

장기중(Ki Jung Chang),이강수(Kang Soo Lee),김현정(Hyun Jung Kim),정해관(Hae Kwan Cheong),오병훈(Byoung Hoon Oh),홍창형(Chang Hyung Hong) 대한노인정신의학회 2009 노인정신의학 Vol.13 No.2

Objectives : We aimed to investigate the relationship between subjective memory complaints and cognition in the elderly. Methods : Data obtained from 1,496 subjects (510 men and 986 women) aged above 60 years was analyzed from the Gwangju Dementia and Mild Cognitive Impairment Study (GDEMCIS). All subjects completed the study questionnaire including demographic characteristics, history of current and past illnesses, drug history, Korean version-Mini Mental State Examination (K-MMSE), and Short Form Korean version of Geriatric depression scale (SGDS-K). Subjective memory complaints were defined in two different ways;worse than others (SMC-O) and worse than one's past (SMC-P). Results : On analysis of covariance, there was significant difference of estimated marginal means of K-MMSE score among five SMC-P groups (much improve : 18.0, little improve : 21.3, not changed : 21.2, little worse : 21.1, much worse : 20.2) after adjusting age, sex, educational level and depression (F=9.63, df=4, p<0.0001, adjusted R2=0.375). There was significant difference of estimated marginal means of K-MMSE score among three SMC-O groups (below peer's average : 20.4, peer's average : 20.9, above peer's average : 21.8) after adjusting age, sex, educational level and depression (F=4.89, df=2, p=0.043, adjusted R2=0.0.361). Conclusion : These results suggest that subjective memory complaints may be an indicator of objective cognitive impairment in the elderly.

小麴酒와 市販藥酒의 成分에 關한 硏究

張基重(Ki-Jung Chang),劉太鐘(Tai-Jong Yu) 한국식품과학회 1981 한국식품과학회지 Vol.13 No.4

노인에서 성별에 따른 알코올사용장애와 인지기능의 관계

김동수,장기중,홍창형,노현웅,노재성,정영기,임기영,장미,손상준 대한노인정신의학회 2016 노인정신의학 Vol.20 No.1

Objective:This study aims to investigate the association between alcohol use disorder and cognition in Korean communitydwelling elderly, especially the gender-specific difference. Methods:Data obtained from 1,141 subjects (976 men and 165 women) aged above 60 years was analyzed from the Gwangju Dementia and Mild Cognitive Impairment Study. All subjects completed the study questionnaire including demographic characteristics, history of current and past illnesses, drug history, Korean Mini-Mental State Examination (K-MMSE), and cut down, annoyed, guilty feelings, eye-opener (CAGE), Short Form of Geriatric Depression Scale-Korean version (SGDS-K). Results:Of the 1,141 subjects (mean age 72.17±6.20, mean educational level 6.50±4.48), 267 demonstrated alcohol use disorder (23.40%) and 874 were non-alcohol use disorder (76.60%). The mean of K-MMSE for alcohol use disorder group was 23.23±4.99, and for non-alcohol use disorder group was 23.70±3.94. When alcohol use disorder is accompanying, the decrement of K-MMSE score was 3.07 for female, and 0.35 for male. And we confirmed the interactive effect on K-MMSE score between sex and alcohol use disorder after adjusting for age, education level, depression (F=5.798, p=0.016). Conclusion:In conclusion, our study demonstrates an association between alcohol use disorder and cognitive impairment by gender in the elderly.

노인의 삶의 질과 시간적 할인율과의 관련성에 대한 고찰

홍석주,장기중,노현웅,노재성,정영기,임기영,홍창형,손상준 대한노인정신의학회 2016 노인정신의학 Vol.20 No.1

Objective:This study aims to examine association of temporal discounting with well-being of Korean community-dwelling elderly. Methods:The subjects of this research were 4,373 community-dwelling older persons without dementia. Each subject was administered the questionnaires regarding the socio-demographic characteristics, temporal discounting which was measured using standard questions in which participants were asked to choose between an immediate, smaller payment and a delayed, larger one. Outcome variable is Korean version of the World Health Organization Five Well-Being Index (WHO-5). Statistical analyses including the Pearson’s correlation test and logistic regression were performed in this study. Results:At baseline, temporal discounting was negatively associated with WHO-5 in the Pearson’s correlation test (r=-0.04, p=0.006). In a adjusted model for confounding variables, temporal discounting was negatively associated with WHO-5 [odd ratio (95% confidence interval)=0.57 (0.35-0.92), p=0.021]. Conclusion:Elderly individual with a higher temporal discounting (which indicates impulsivity) may have a lower quality of life.

FT-IR 스펙트럼 기반 다변량통계분석기법에 의한 두과작물의 대사체 수준 식별체계 확립

송승엽,하태정,장기창,김인중,김석원 한국식물생명공학회 2012 식물생명공학회지 Vol.39 No.3

본 연구에서는 국내에서 재배중인 대표적인 두과작물(대두, 완두, 강낭콩, 팥, 녹두, 동부)종자로부터 전세포추출물의 FT-IR 스펙트럼 데이터로부터 다변량통계분석(PCA, PLS-DA, HCA)을 이용하여 신속하고 간편한 종 구분체계를 확립하였다. 대사체수준에서 팥, 녹두, 동부는유연관계가 높음을 알 수 있었으며 대두, 완두, 강낭콩은비록 두과작물이지만 차이가 매우 큼을 알 수 있었다. 아울러 본 연구에서 얻어진 대사체 정보의 다변량통계분석에 의한 유연관계분석은 흥미롭게도 두과작물의 계통분류학적 유연관계와 밀접한 상관관계를 나타내었다. 따라서 FT-IR 스펙트럼 데이터의 다변량통계분석은 방법의간편성과 신속성을 고려할 때 두과작물의 계통이나 품종의 신속한 식별 수단으로 활용이 가능할 것으로 기대된다. 또한 두과작물의 기능성 성분 함량 정보가 성공적으로 연계된다면 본 연구에서 확립된 대사체 기반 신속식별체계는 기능성 성분의 함량이 높은 계통이나 품종의조기 선발수단으로 활용이 가능할 것으로 기대된다. To determine whether FT-IR spectroscopy combined with multivariate analysis for whole cell extracts can be used to discriminate major leguminous plant at metabolic level, seed extracts of six leguminous plants were subjected to Fourier transform infrared spectroscopy (FT-IR). FT-IR spectral data from seed extracts were analyzed by principal component analysis (PCA), partial least square discriminant analysis (PLS-DA) and hierarchical clustering analysis (HCA). The PCA could not fully discriminate six leguminous plants, however PLS-DA could successfully discriminate six leguminous plants. The hierarchical dendrogram based on PLS-DA separated the six leguminous plants into four branches. The first branch was consisted of all three Vigna species including Vigna radiata var. radiate, Vigna angularis var. angularis and Vigna unguiculata subsp. Unguiculata. Whereas Pisum sativum var. sativum, Glycine max L and Phaseolus vulgaris var. vulgaris were clustered into a separate branch respectively. The overall results showed that metabolic discrimination system were in accordance with known phylogenic taxonomy. Thus we suggested that the hierarchical dendrogram based on PLS-DA of FT-IR spectral data from seed extracts represented the most probable chemotaxonomical relationship between six leguminous plants.

보험회사(保險會社)의 리스크 증대(增大)와 대응(對應)

리기형,박중영,장기중 보험연구원 1998 조사보고서 Vol.1998 No.6

노인의 주관적 행복감에 영향을 미치는 스트레스 요인

김성주,노재성,노현웅,장기중,정영기,이윤환,임기영,한창수,김진주,박미애,홍창형,손상준 대한노인정신의학회 2015 노인정신의학 Vol.19 No.1

Objective:This study aims to identify self-reported stressors in the Korean community-dwelling elderly and examine their effects on subjective well-being. Methods:The subjects of this research were 1,010 elderly people who lived in Suwon, Korea. Each subject was administered the questionnaires regarding the socio-demographic characteristics, self-reported stressors, Concise Measure of Subjective Well-Being (COMOSWB) consisting of life satisfaction, positive emotion and negative emotion, Mini-Mental State Examination for dementia screening and Short Form Geriatric Depression Scale-Korean version. Statistical analyses including the Pearson’s correlation test and multiple linear regressions were performed in this study. Results:In our adjusted model for confounding variables, stress from physical problems (S-PP) (ß=-0.133, p<0.001), stress from loneliness or solitude (S-LS) (ß=-0.077, p=0.007), stress from family members (S-FM) (ß=-0.083, p=0.001) were negatively associated with the total score of COMOSWB. In subscale analyses of COMOSWB, we also found that S-PP (ß=-0.184, p<0.001), S-LS (ß=-0.077, p=0.014), stress from economic problems (ß=-0.072, p=0.021) were negatively associated with life satisfaction score. While S-PP (ß=-0.140, p<0.001) and S-FM (ß=-0.079, p=0.003) were negatively associated with positive emotion score, S-FM (ß=0.105, p=0.001) and stress from friends and neighbors (ß=0.072, p=0.016) were positively associated with negative emotion score. Conclusion:Stresses from physical problems, loneliness, and family members might be associated with subjective well-being in the elderly. While life satisfaction appears to be affected by one’s perceived physical health status, loneliness, and economic conditions, positive and negative emotions appear to be affected by relationships with family members, friends, or neighbors.

노인성 우울증 환자에서 지역사회 기반 ‘목표달성 프로그램’의 효용성

강규하(Gyu Ha Kang),장기중(Ki Jung Chang),임현국(Hyun Kook Lim),한진주(Jin joo Han),이은희(Eun Hee Lee),노현웅(Hyun Woong Roh),노재성(Jai Sung Noh),정영기(Young Ki Chung),임기영(Ki Young Lim),홍창형(Chang Hyung Hong),손상준(Sang Joon 대한노인정신의학회 2017 노인정신의학 Vol.21 No.1

Objective:This study aimed to investigate the effect of community-based Goal-Achieving program in geriatric depressive symptoms preliminarily. Methods:We obtained data from elderly Korean subjects with major depressive disorder (n=51) aged 60 years or older at baseline, taking case management from community mental health center. Subjects were randomly assigned to intervention group (n=24) and control group (n=27). We investigated depressive symptoms through Short Form Geriatric Depression Scale-Korean version (SGDS-K) at baseline and every month for 3 months to all subjects. We tested interaction between group and time in SGDSK score to evaluate the effect of program. And post hoc test examined between group differences of SGDS-K at each time points. Results:In quadratic linear mixed effects model analysis, interaction between group and time was statistically significant (Total SGDS-K score : coefficient=0.29, p<0.001 ; SGDS-K dysphoria subscale : 0.18, p<0.001 ; SGDS-K hopelessness subscale : 0.05, p=0.089 ; SGDS-K cognitive impairment subscale : 0.06, p=0.003). And significant between group difference was shown in post hoc test at time points of third month (SGDS-K score of control group : SGDS-K score of intervention group=10.74±3.482 : 7.25±4.475, p=0.0184). Conclusion:These results may suggest that ‘Community-based the Goal-Achieving program’ has efficacy in reducing geriatric depressive symptoms.