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각종피부질환 (各種皮膚疾患 ) 의 혈액상 (血液象 ) 에 관한 연구
임수덕 대한피부과학회 1960 大韓皮膚科學會誌 Vol.1 No.1
So far today the blood Picture of specific dermatoses such as leprosy, syphilis, skin tubercuIosis, pemphigus and eczema was studied a good many ways. Author has studied the blood picture especially red blood cells, hemoglobin, hematocrit, white blood cells and its differential counts in 217 cases of various skin diseases such as contact. dermatitis, urticaria, chronic eczema, atoPic dermatitis, seborrheic dermatitis, erythema multiforme, erythemanodosum, drug eruption, prurigo, lichen urticatus, exfoliative dermatitis and purpura. At the same time liver function tests were performed in 46 cases including 25 cases of contact dermatitis, 6 cases of chronic eczema, 5 cases of atopic dermatitis, 5 cases of urticaria and 5 cases of exfolistive dermatitis. Afterwards the correlations of those two groups were investigated. Among all mentioned above dermatose except purpura no changes of red blood cells, hemogiobin and hematocrit were observed according to the authors own control of normal values which were obtained in 62 normal healthy adults. Other findings are as follows; 1. In contact dermatitis leucocytes and eosinophils are increased while neutrophils slightIy decreased. 2. Moderate increase of lymphocytes in urticaria. 3. In chronic eczema leucocytes and lymphocytes slightly increased but neutrophils somewhat decreased. 4. In atopic dermatitis leucocytes and eosinophils increased and there was also moderate increase of lyrnphocytes. 5. In seborreheic dermatitis monocytes and basophils were increased but eosinophils were slightly increased. 6. In erythema multiforme monocytes were decreased and leacocytes increased slightly. 7. In erythema nodosum neitrophils increased and lymphocytes and monocytes were decreased. 8. In drug eruption monocytes were decreased. 9. ln Prurigo eosinophils were increased. 10.ln lichen uiticatus neutrophils were decreased. 11. In exfoliative dermatitis there are marked increase of leucocytes and eosinophils and decrease of neutrophiIs, lymphocytes and basophils. 12. In purpura red b!ood cells, hemoglobin, hematocrit were decreased. The increase of white blood cells in contact dermatitis and exfoliative dermatitis almost paralleled with the extension of their lesions. Marked liver function disturbarces were found in a good many cases cf exfoliativedermatitis while slight degree of liver function disturbances were found in some cases of contact dermatitis and it was found that some cases of chronic eczema, urticaria and atopic dermatitis gave some influence to liver function. The fact of leucocytes increase in exfoliative dermatitis and contact dermatitis seems more or less go parallels with liver function disturbances.
유극세포암 (有棘細胞癌) 을 병발한 색소성건피증의 Bleomycin 에 의한 치험예 (治驗例)
임수덕,김풍명,홍재익 대한피부과학회 1971 대한피부과학회지 Vol.9 No.2
Xeroderma pigmentosum, a rare, genetically determined dermatosis, is often cornplicated by malignant chagnes of various types-most commonly, basal-cell epithelioma, squamous cell epithelioma, less frequently malignant meIanoma, keratoacanthoma, fibrosarcoma, and endothelioma have been reported. In Korea, no case has ever been reported in literature except four cases at a symposium for dermatology, two of them complicated by basal-cell epithelioma, and the others by squamous cell epithelioma. This case reported was complicated by squamous cell epithelioma. As one of the anticancer treatments, especially for skin cancer, Bleomycin is, now, drawing the attention for its high therapeutic index with only few side effects. For this case, we injected Rleomycin 15mg at once, twice a week, for 8 weeks, So total injection was 16 times and 240mg of Bleomycin was given in total. While this amount given for this case was not enough for the complete treatment of squamous cell epithelioma, we got the following results: 1. Clinically, the ulcerated lesion of the cancer on the right ala nasi had shrunken in size with reepithelialization at the margin showing clear surface, and 2. microscopically, the atypical cancer cell masses and individual cell keratinizations had been decreased in size and in number, and less remarkable comparing to those in untreated stage at his first visit to the hospital.
임수덕,조중재,황진수,조용환,Im, Su Deok,Jo, Jung Jae,Hwang, Jin Su,Jo, Yong Hwan 한국통신학회 1999 韓國通信學會論文誌 Vol.24 No.12
본 연구에서는 IMT-2000 서비스의 상용화 실시 시기를 전문가 의견을 바탕으로 하여 예측한 결과 2001년 2월경에 첫 서비스를 실시할 것으로 나타나 전문가들은 대체로 빠른 진척을 예상하고 있음을 알 수 있었다. 또한 본 연구의 가장 중요한 부분인 IMT-2000 서비스 가입 수요예측에서는 가격 경쟁력에 대한 두 가지 경우에 따라 다른 모형을 제시하였다. 본 연구에서는 신제품에 대한 수요예측에 정성적 방법인 전문가 의견법과 정량적 방법인 성장곡선 모형을 결합하여 과거자료가 없는 신제품의 수요예측의 오차를 줄이고자 하였다. 각 성장곡선 모형에 필요한 계수를 전문가들의 주관적인 의견을 근거로 하여 추정하였다. In this paper, we forecast launching time of the commercial IMT-2000 service as feb. 2001, according to expert’s opinion, and most of they forecast rapid evolution. And, we propose two different models according to two cases for competition power of price for IMT-2000 service subscriber demand forecasting. In this paper, we combine the expert’s opinion method with the growth curve model for demand forecasting for new products in order to reduce error of the demand forecasting that haven’t past references. The estimation of needed coefficients for each growth curve model is based on experts’ subjective opinions.