수영이 흰쥐 해마 치상회에서 산화질소합성효소의 발현에 미치는 영향

임백빈 ( Baek Vin Lim ),박진국 ( Jin Kook Park ) 한국운동영양학회 2004 Physical Activity and Nutrition (Phys Act Nutr) Vol.8 No.3

The purpose of the present study was to investigate the effect of swimming on nitric oxide synthase expression in the hippocampal dentate gyrus of the Sprague-Dawley (SD) rats. The male SD rats weighing 250±10 g (6 weeks old) were used in the experiment. In the first part of the experiment (involving session duration-dependence swimming), the rats were divided into five groups to investigate an optimum duration of swimming exercise for the prevention of the NO-dependent neuronal damage: control group, 1-min-swimming group, 5-min-swimming group, 10-min-swimming group, and 20-min-swimming group (n = 10 in each group). In the second part of the experiment (involving training duration-dependence swimming), the rats were divided into five groups: control group to investigate an optimum program of swimming training for the prevention of the NO-dependent neuronal damage, I-day-swimming group, 3-day-swimming group, 7-day-swimming group, and 14-day-swimming group (n = 10 in each group). The rats in the session duration-dependence swimming groups were made to swim for 1 min, 5 min, 10 min, and 20 min once a day for 3 consecutive days, respectively. The rats in the program duration-dependence swimming groups were made to for 10 min once a day for 1 day, 3 days, 7 days, and 14 days, respectively. The swimming apparatus consisted of a swimming pool with 60 cm in height and 120 cm in diameter, which was filled with water at a temperature of 30-32℃ up to 45 cm from the bottom. With respect to the session-duration-dependence swimming groups. the two swimming groups of 10 min or longer duration significantly decreased the number of NADPH-d-positive cells in the dentate gyrus compared to either the control group (p = 0.001) or the I -min swimming group (p = 0.001) or the 5-min swimming group (p = ??). With respect to the program-duration swimming groups, all the swimming groups regardless of its training frequencies had significantly decreased NADPH-d-positive cells in the dentate gyrus compared to the control group (p = 0.03). In conclusion, these results of the current study suggest that a single bout of swimming lasting longer than 10 min, regardless of its frequency, may be an effective means for the prevention of NO-dependent neuronal damage.

운동종목에 따른 안지오텐신 전환효소와 베타3-아드레날린 수용체 유전자형의 상대적 빈도

임백빈 ( Baek Vin Lim ),최강덕 ( Kang Duk Choi ),전광주 ( Gwang Joo Chun ),박현 ( Hyon Park ) 한국운동영양학회 2006 Physical Activity and Nutrition (Phys Act Nutr) Vol.10 No.3

건강도시프로젝트에서의 도시건강프로파일 개발사례

임백빈(Baek-Vin Lim),고광욱(Kwang-Wook Koh),김희숙(Hee-Suk Kim),신용현(Yong-Hyun Shin) 한국보건교육건강증진학회 2014 보건교육건강증진학회지 Vol.31 No.3

Objectives: Although many cities have adopted Healthy Cities approach in Republic of Korea, few studies have been reported about city health profile. So we report a case of city health profile made of subjective indexes and objective indicators using available recent evidence. Methods: To assess subjective city health indexes, questionnaire survey was implemented to public officers and citizen adapting the ‘Signs of progress, signs of caution of 12 stage tool from Ontario Healthy Community Coalition. Based on recent literature objective city health indicators were collected for time-series comparison and for the comparison with those of larger province mainly using Korean Statistical Information Service. Results: Subjective city health indexes were successfully constructed in four areas including human health, environment, social and economic area. The score was especially low in environmental area. Specific items in each area for improvement were identified. Objective city health indicators were collected for three year time-series comparison and for the compared with those of larger province. Conclusions: City health profile comprised of subjective city health indexes and objective city health indicators could successfully be made from primary survey and secondary data in a medium-sized Korean city. That City health profile was useful in subsequent city health planning through participatory process.

서비스블루프린트를 적용한 할랄식 한식당 구축 제안연구

임백빈(Lim, Baekvin),이성필(Lee, Sungpil),김경도(Kim, Kyungdo) 인제대학교 디자인연구소 2012 Journal of Integrated Design Research (JIDR) Vol.11 No.4

본 연구의 목적은 부산을 찾는 이슬람 관광객들이 안전하게 믿고 찾을 수 있는 할랄식품을 사용한 한식당의 모델을 제안하고자 하는 데 있다. 연구대상과 방법으로는 부산에 있는 한식 외식업체 밥상과 할랄 음식점 Sangam을 선택하여, Lovelock의 서비스블루프린트를 활용하여 비교 분석하고 맛, 공간, 서비스에 대한 설문조사를 실시한 후 결과를 기반으로 심층면접을 통해 최종적으로 이미지맵 조사를 실시하였다. 본 연구를 통하여 알게 된 할랄 식품을 사용한 한식당의 제안된 내용은 다음과 같다. 첫째, 무엇보다도 음식에 대한 신뢰를 줄 수 있는 요소가 우선 되어야 하며 둘째, 맛에 대한 요소로 한식과 동남아 음식을 포함한 메뉴 구성과 한국전통다과를 맛 볼 수 있는 기회가 있음을 선호하였다. 셋째, 공간적인 요소로 음식점의 위치는 바닷가 혹은 시내가 보이는 곳을 선정, 식사와 기도를 함께 할 수 있는 개별 룸과 샤워기형 세면대가 갖춘 기도하기 전 씻을 수 있는 공간 그리고 한국을 알 수 있는 체험공간과 기념품 코너가 있는 것을 선호하였다. 넷째, 서비스 요소로는 영어가 가능한 직원과 요리사 중 무슬림이 포함되어 있는 것과 식사 전, 후 물티슈 등의 위생용품 그리고 기도를 위한 양탄자 대여서비스를 필요로 함을 알 수 있었다. 본 연구에서는 부산을 찾는 무슬림을 위한 할랄식품을 사용한 한식당 모델을 서비스디자인 방법론을 통하여 제안하였다. 차후 연구에서는 할랄음식점 활성화를 위한 할랄식품 운송과 보관을 위한 방법, 무슬림 관광 서비스 분야, 할랄 식품을 사용한 호텔 등 보다 다양한 분야로 연구를 확대해 나갈 예정이다. The aim of this study is to propose a model of Korean model of Halal Korean restaurant which can be found by Islam tourists to Busan. As materials and methods, Korean restaurant "Bapsang" in Busan and Halal restaurant "Sangam" were selected. Then those were compared and analyzed by using service blueprint of Lovelock and interview was conducted based on the survey results of taste, space and service. Finally, imagemap research was conducted. Proposals for Halal Korean restaurant through this study are as follows: Above all, trust in food components should be the first. Second, as elements for taste, menus including Korean and Southeast Asian food and opportunity for tasting Korean traditional refreshments were preferred. Third, as the spatial position element, restaurant overlooking the beach or the city was selected and individual room to have a meal and pray together was preferred. Additionally, small space with separate shower and washstand to wash up before praying and experience space to learn Korean culture and souvenir corner were preferred. Fourth, some other prime elements were found out : An English-speaking person and Muslim cook should be staffed. Sanitary wipes before/after the meal and prayer rug should be offered. In this study, a model of Halal Korean restaurant was proposed for Muslims to visit Busan through service design methodology. For further steps, future research will be expanded to various fields like methods for transportation and storage of Halal food, Muslims tourism service area and hotels serving Halal food, etc.

고온과 저온 환경에서의 트레드밀 운동이 흰쥐 해마에서 c-Fos 발현과 비복근에서의 HSP 70 발현에 미치는 영향

임백빈(Baek-Vin Lim) 한국생활환경학회 2009 한국생활환경학회지 Vol.16 No.6

In the present study was to examine the effect of treadmill exercise under heat and cold stress conditions on c-Fos expression in the hippocampus and HSP 70 expression in the gastrocnemius muscle. c-Fos expression represents neuronal activity and plays a crucial role in the brain development. Physical exercise is known to enhance neuronal plasticity and activity. Heat shock protein 70 (HSP 70) is the best characterized stress-responsive gene with enhanced expression and thought to be a protective factor against environmental stress in a cell. For this study, male Sprague-Dawley rats weighing 250±10 g (7 weeks in age) were used. The rats were randomly divided into six groups (n=10 in each group): the control in 4℃ group, the exercise in 4oC group, the control in 22℃ group, the exercise in 22℃ group, the control in 35℃ group, and the exercise in 35℃ group. The environmental temperature at 22℃ set as the normal conditions, 4℃ was as the cold stress conditions and 35℃ was as the heat stress conditions. In the cold conditions, the temperature was 4oC with relative humidity 40%. In the normal conditions, the temperature was 22℃ with relative humidity 40%. In the heat stress conditions, temperature was 35℃ with relative humidity 20%. Animals were sacrificed immediately after finishing the last session of treadmill exercise on the 5 weeks of the experiment. The present results showed that exposure under normal, cold and heat stress conditions exerted no signifiant effect on the c-Fos expression. However, the c-Fos expression in the hippocampus was increased by treadmill exercise, showing that cold stress and heat stress acted as the decreasing factor of c-Fos. The HSP 70 expression in the gastrocnemius was increased by treadmill exercise for 5 weeks under normal, cold and heat conditions, however, the increasing of HSP 70 was not appeared that exposure under the cold and heat stress conditions. The present study revealed that treadmill exercise exerted improvement effect on impairment of environmental stress through enhancing of c-Fos and increasing of HSP 70.

Vitamin D receptor 유전자 다형성에 대한 일반인과 운동종목별 상대적 빈도 연구

임백빈(Baek-Vin Lim) 한국코칭능력개발원 2007 코칭능력개발지 Vol.9 No.4

수영운동이 쥐의 해마 치상회 세포생성에 미치는 영향

임백빈(Baek Vin Lim),박진국(Jin Kook Park),장명제(Myoung Jei Chang),신말순(Mal Soon Shin),김창주(Chang Ju Kim) 한국사회체육학회 2004 한국사회체육학회지 Vol.0 No.21

수영 운동이 쥐의 해마 치상회에 세포 생성에 미치는 영향을 5-bromo-2`-deoxyuridine(BrdU) 면역 조직화학법을 이용하여 연구하였다. 첫 번째 실험에서 수영 운동집단은 1분 수영군, 5분 수영군, 10분 수영군, 20분 수영군으로 나누어 3일간 수영운동을 실시하였다. 두 번째 실험은 1일 수영군, 3일 수영군, 7일 수영군, 14일 수영군으로 분류하여 1일 10분씩 수영운동을 실시하였다. 본 실험의 결과, 10분간의 수영 운동이 치상회의 세포생성을 가장 효과적으로 증가시켰으며, 또한 7일간의 수영 운동이 세포생성을 가장 많이 시키는 것으로 나타났다. 이러한 결과로 미루어보아 수영운동이 치상회의 세포생성을 증가시키는 운동요법으로 사용될 수 있을 것으로 생각된다.

저온 노출이 인지기능과 뇌신경세포생성에 미치는 영향

임백빈 ( Beak Vin Lim ),이성필 ( Sung Pil Lee ) 한국감성과학회 2011 감성과학 Vol.14 No.3

In the present study was to examine the influence of cold stress conditions on memory function in relation with 5-hydroxytryptamine(serotonin, 5-HT), trptophanhydroxylase(TPH) expression and cell proliferation in the hippocampus. For this study, male Sprague-Dawley rats weighing 250 ± 10 g(7 weeks in age) were used. The rats were randomly divided into three groups(n = 10 in each group): the 22℃-control group, the 4℃-3 days group, the 4℃-5 weeks group. The environmental temperature at 22℃ set as the normal conditions, 4℃ was as the cold stress conditions. The present results showed that cold stress conditions shorten latency, representing cold stress disturbed memory function. 5-HT and TPH expressions in the dorsal raphe were increased cold stress. Neurogenesis in the dentate gyrus was increased under cold conditions. The present study revealed that cold stress exerted deteriorative memory function. However, through increasing of 5-HT, TPH and BrdU expression under cold stress conditions did not show memory enhancing effect.

최적화된 노인여가시설 구축을 위한 서비스디자인 기초연구

임백빈 ( Beak Vin Lim ),김형찬 ( Hyeong Chan Gim ),이성필 ( Sung Pil Lee ) 한국감성과학회 2010 감성과학 Vol.13 No.4

The purpose of this study to prepare for an aging society and older people happy is important to build recreational facilities gwajera recognize and physically old man of leisure facilities as a basis for the destroyers of the current seniors in public institutions that provide recreational facilities for About under utilized factors was investigated. The specific research methods and information, first, at home the most successful public senior leisure facilities as a model for selected Daegu Senior seutawo visit the simple survey and observation through the pros and cons about the elements that organize and KJ Technique and graft technique (Graph Theory) by applying the elements of physical space limitations on the mutual relationship between the priorities and establish guidelines for the priority was extracted. In addition, field-aged feel the satisfaction of their leisure facilities to evaluate the visits to the Busan, Sasang elderly and local leisure facilities for the elderly surveyed had taken Priority Method is based on comparison of results and final was to organize things to improve. Through this study, first, goods and equipment to the leisure space of the elderly efforts to effectively deploy the expertise to deal with and it actually showed that it is also important. Second, using physical devices and programs for the elderly aged recreational facilities are important, but physical and mental characteristics to consider voluntary participation for the type of space could see that it is important.

이침(耳鍼)이 절식(絶食)시킨 흰쥐의 뇌신경세포(腦神經細胞) 활성변화(活性變化)에 미치는 영향(影響)

김이화,김연정,임백빈,장미현,정주호,김창주,Kim, Ee-Hwa,Kim, Youn-Jung,Lim, Baek-Vin,Jang, Mi-Hyun,Chung, Joo-Ho,Kim, Chang-Ju 대한침구의학회 2001 대한침구의학회지 Vol.18 No.1

Objective : The aim of this study was to investigate the effectiveness of stimulation of specific auricular acupuncture points on appetite suppression. Methods : The fasted rats were deprived of food and water for 48 hours. Stimulation of tho inner auricular region of the rat correspond to the human stomach acupuncture point was made for leptin, tryptophan hydroxylase (TPH) and c-fos expression in the brain of the fasted rats by immunohistochemistry. Results : The immunoteactivities of leptin in the periventricular nucleus of the auricular acupunctured group with fasted were significantly higher compared to those of the fasted group. The immunoreactivities of TPH in the median raphe neucleus and reticulotegmental neucleus pons of the auricular acupunctured group with fasted were significantty higher compared to those of the fasted group. And the immunoreactivities of c-fos in the dentate gyrus of the auricular acupunctured group with fasted were significantly lower compared to those from the fasted group. Conclusions : We conclude that the auricular acupuncture altered leptin and TPH-expression in the brain of the fasted rats. The results suggest that auricular acupuncture may inhibit food intake.