Usefulness of Cytologic Study of Intraoperative Suction Fluid in Brain Tumors

이혜경,이형진,이은희,김희정,이일우,Lee, Hye-Kyung,Lee, Hyung-Jin,Lee, Eun-Hee,Kim, Hee-Jung,Lee, Il-Woo The Korean Society for Cytopathology 2002 대한세포병리학회지 Vol.13 No.2

In diagnosing a brain tumor, it is essential to obtain samples from many areas of the tumor. Although there are reports about the suitability of material obtained by cavitron ultrasonic surgical aspirator(CUSA), there is a paucity of reports regarding conventional intraoperative suction. This study was performed to evaluate the usefulness of the suction fluid and the effect of different hemolytic fixatives. Intraoperative suction fluid was obtained from 2 pituitary adenomas and 2 choroid plexus carcinomas. In two cases of mixed astro-oligodendroglioma, one of glioblastoma multiforme and 3 of meningioma, the fluid was collected by CUSA. Each sample was divided into four bottles for the different fixatives such as 0.1N HCI, 10% acetic acid, 95% alcohol, and no additive. All cases were evaluated by the both cytologic smear and cell block preparations, and were reviewed with concomitant histologic diagnosis. The result showed a good correlation between the cytologic study and the histologic diagnosis and 95% alcohol was found to be superior to other fixatives in ceil preservation.

스폰지 목욕에 대한 미숙아의 생리적상태 및 행동반응

이혜경,홍경자,남은숙,이영희,정은자,Lee Hae Kyung,Hong Kyung Ja,Nam Eun Sook,Lee Young Hee,Jung Eun Ja 한국아동간호학회 2000 Child Health Nursing Research Vol.6 No.1

A descriptive exploratory design was used in this study to evaluate the effects of sponge bathing on physiological(heart rate, heart period, vagal tone, oxygen saturation, respiration) and behavioral responses in newly born 40 preterm infants from intensive care unit of S University Hospital in Seoul. Data has been collected from October, 1997 to March, 1999. The infants were between 27-33 weeks gestational age at birth, and were free of congenital defects. The subjects entered the protocol when they were medically stable (determined by initiation of feeding and discontinuation of all respiratory support) but still receiving neonatal intensive care. The infants' physiologic parameters were recorded a 10 - minute before, during, and after bathing. Continuous heart rate data were recorded on a notebook computer from the infant's EKG monitor. The data were digitized off-line on software(developed by Lee and Chang in Wavelet program) which detected the peak of the R wave for each heart beat and quantified sequential R-R intervals in msec(i.e. heart periods). Heart period data were edited to remove movement artifact. Heart period data were quantified as : 1) mean heart period; 2) vagal tone. Vagal tone was quantitfied with a noninvasive measure developed by Porges(1985) in Mxedit software. To determine behavioral status, tools were developed by Scafidi et al(1990) were used. Collected data were analyzed with the SPSS program using paried t-test, ANOVA, and Pearson correlation. The result were as follow. 1. The results of the ANOVAs indicated that vagal tone were signifcantly lower during bathing than baseline and post-bathing. There were significant differences in heart period and heart rate levels across the bathing. But the mean oxygen saturations and respirations were no differences. Also, there were no significant differences on behavioral sign, motor activity, behavioral distress, weight changes, morbidity, and hospitalization period. 2. To evaluate the relation between vagal tone and subsequent parameters, the two groups (the high group had 19 subjects and low group had 21subjects) were divided by the mean baseline vagal tone. Vagal tone measured prior to bathing were significantly associated with respiration before bathing, vagal tone during bathing, and the magnitude of change in both vagal tone. But, other subsequent reactivities were no differences in two groups. 3. Correlations were also calculated between vagal tone and the subsequent physiological reactivities from baseline through after- bathing. Correlations were significant between baseline vagal tone and baseline heart rate, between baseline vagal tone and baseline heart period, between baseline vagal tone and oxygen saturation after bathing. In summary, the bathing in this study showed a stressful stimulus on premature infants through there was significance in the physiological parameters. In addition, our study represents the documentation that vagal tone reactivity in response to clearly defined external stimulation provides an index of infant's status.

체액 검체에서 톨루이딘 블루 염색의 유용성

이혜경,주명진,이광민,이은희,심상인,Lee, Hye-Kyung,Joo, Myung-Jin,Lee, Kwang-Min,Lee, Eun-Hee,Sim, Sang-In 대한세포병리학회 1999 대한세포병리학회지 Vol.10 No.1

We evaluated the availability of toluidine blue stain in body fluids, such as peritoneal and pleural fluid and urine. Nine hundreds specimens, i.e., 400 pleural and 400 peritoneal fluids and 100 urine samples, respectively, from Jan. 1995 to May 1996 were included. We obtained the result of high sensitivity and high specificity. In toluidine blue stained body fluid in comparison with Papanicolaou stained result. Additionally, we found the diagnostically important crystals in chylothorax and some urine samples, which can not be seen in routine Papanicolaou stain. We thought the toluidine blue stain in body fluid is one of very useful diagnostic methods.

폐암진단을 위한 객담세포검사 결과 - 16개월간의 전주 예수병원 객담세포검사 결과를 바탕으로 -

이혜경,이광민,정동규,강대송,김귀완,Lee, Hye-Kyung,Lee, Kwang-Min,Chung, Dong-Kyu,Kang, Dae-Song,Kim, Kwi-Wan 대한세포병리학회 1994 대한세포병리학회지 Vol.5 No.2

A prospective survey of sputum cytologic specimen was performed for 16 months from Jan. 1993 to Apr. 1994 in Presbyterian Medical Center. The purpose of this study is to find the positive rate of sputum cytology in the diagnosis of lung cancer and to correlate these results with tumor location and stage. Sputum cytologic specimen were received from 104 patients among 158 patients diagnosed as lung malignancy by histologic examination. Cytologic diagnosis of "suggestive of malignancy" was made in 61 patients (59%) and dysplasia in 9 patients(9%), atypia in 14 patients(13%), benign in 15 patients(14%) and inadequate specimen in 5 patients (5%), respectively. Among 84 patients beyond the cytologic diagnosis of atypia, 51 patients (61%) disclosed a central location, while 33 patients (39%) showed peripheral lesions. All 54 patients diagnosed as suggestive of non-small cell carcinoma were stage III or over, and all 7 patients diagnosed as suggestive of small cell carcinoma were in advanced stage. These results suggest that the cytologic examination of sputum seems to be an important tool in diagnosis of lung cancer.

갑상선 림프종의 세침흡인 세포학적 소견 -2 예 보고-

이혜경,이종민,강창석,Lee, Hye-Kyung,Lee, Jong-Min,Kang, Chang-Suk 대한세포병리학회 2002 대한세포병리학회지 Vol.13 No.1

We report two different types of thyroid lymphoma associated with Hashimoto's thyroiditis. Both showed autoantibodies and were compatible with Hashimoto's thyroiditis according to their clinical backgrounds. A 76-year-old female noted a painless, rapidly growing mass in her neck which was diagnosed as diffuse non-Hodgkin's lymphoma, large cell type, after the fine needle aspiration cytology of the thyroid. She underwent chemo-radiotherapy and is free of the disease 10 months after diagnosis. The other patient, a 73-year-old female with a diffuse golfer, was diagnosed on fine needle aspiration cytology as having Hashimoto's thyroiditis. Three years later she developed a hard nodular growth in the both lobes of the thyroid. This was subjected to fine needle aspiration cytology and needle biopsy and was diagnosed as a MALT lymphoma. She refused any treatment and died 12 months after the diagnosis.

21세기 지식사회형 교육복지

이혜경,Lee, Hye-Gyeong 한국사회복지사협회 2005 Social workers Vol.1 No.-

국내대학의 학술논문 공동연구 기여도 산정 기준 비교 분석

이혜경,양기덕,Lee, Hyekyung,Yang, Kiduk 한국도서관정보학회 2015 한국도서관정보학회지 Vol.46 No.4

As the first step in developing the optimal co-authorship allocation method, this study investigated the co-authorship allocation standards of Korean Universities on journal publications. The study compared the standards of 27 Korean universities with Library and Information Science (LIS) departments, and analyzed author rankings generated by applying inflated, fractional, harmonic, and university standard method of co-authorship allocation to 189 Korean LIS faculty publications from 2001 to 2014. The university standards most similar to the standard co-authorship allocation method in bibliometrics(i.e. Vinkler) were those whose co-author credits summed up to 1. However, the university standards differed from Vinkler's in allocating author credits based on primary and secondary author classification instead of allocation based on author ranks. The statistical analysis of author rankings showed that the harmonic method was most similar to the university standards. However, the correlation between the university standards whose co-author credits summed up to greater than 1 and harmonic method was lower. The study results also suggested that middle-level authors are most sensitive to co-authorship allocation methods. However, even the most generous university standards of co-authorship allocation still penalizes collaborative research by reducing each co-authors credit below those of single authors. Follow-up studies will be needed to investigate the optimal method of co-authorship credit allocation. 본 연구는 보편적이고 타당한 학술논문 공동연구 기여도 산정 기준의 개발을 도모하기 위하여, 국내대학의 교수연구업적평가 중 학술논문 공동연구 기여도 산정 기준을 분석하였다. 국내 문헌정보학과가 포함된 종합대학 27개교의 규정과 189명의 국내 교수들의 2001년~2014년간의 학술논문 데이터를 수집하여 첫 번째 학교기준들을 비교하였으며, 두번째 공동연구의 기여도 세 가지 산정식(Inflated, Harmonic, Fractional)과 학교기준을 적용하여 도출한 순위를 통계적으로 분석하였다. 계량서지학의 대표적인 공동연구 기여도 기준(i.e Vinkler)과 가장 유사한 기준은 기여도 총합이 1인 학교기준이었으며, 국내의 저자역할은 제1저자, 교신저자, 공동저자로만 구분하하고 있었다. 한편 순위의 통계분석 결과, 학교기준과 가장 유사한 기준은 Harmonic 방식이었으나, 학교기준 중 1보다 큰 기준과 Harmonic방식이 순위 상관이 상대적으로 차이가 나타났으며, 이러한 결과는 논문의 수가 중간수준인 저자일 경우, 산정식 형태에 따라 기여도 순위가 변동될 수 있음을 추측 할 수 있었다. 그러나 공동연구에서 가장 많은 기여도를 받는 학교기준을 적용할지라도 단독연구만큼의 기여도는 받지 못하였으며, 이는 연구자들이 공동연구를 기피하고 지양하는 한 요소가 될 수도 있다. 이에 타당한 공동연구 기여도 측정 개발을 위하여 정성적 연구방법을 포함한 후속연구가 지속 되어야 한다.

귀밑샘의 상피-근육상피암종의 세침흡인 세포소견 -2예 보고-

이혜경,장은주,김주헌,강동욱,손현진,박미자,Lee, Hye-Kyung,Jang, Eun-Joo,Kim, Joo-Heon,Kang, Dong-Wook,Son, Hyun-Jin,Park, Mee-Ja 대한세포병리학회 2008 대한세포병리학회지 Vol.19 No.2

Epithelial-myoepithelial carcinoma (EMC) is a rare low grade malignant tumor of the salivary glands and it shows a characteristic biphasic population of epithelium and myoepithelium. It shows various cytologic and histologic features, so making an exact diagnosis is difficult. We report here on two cases of epithelial-myoepithelial carcinoma arising from the parotid gland and we compare the cytologic findings of the aspirated samples with the histologic findings of the tumors. We think the finding of mixed pattern of large, clear myoepithelia and small epithelia is the most valuable finding in the diagnosis of EMC.

도시홍수 방재를 위한 그린 인프라스트럭처 공간분석

이혜경,Lee, Hye Kyung 한국BIM학회 2020 KIBIM Magazine Vol.10 No.4

Green Infrastructure has been considered as one of strategies for flood mitigation in cities. Although, the diverse benefits of green infrastructure implementation are studies, there is a lack of research on the relationship between spatial composition and configuration of green infrastructure and urban flood mitigation. To address this gap, this study 1) utilized high-resolution satellite imagery to analyze spatial composition and configuration of green infrastructure in highly developed seven cities in South Korea, and 2) conducted an empirical analysis to find the relationship between economic losses from flooding and spatial patterns of green infrastructure and development patterns. The results of this research will be helpful for urban planners to prepare green infrastructure implementation guidelines for effective urban flood mitigation.

파리 기후협정의 채택과 국내적 시사점

이혜경,Lee, Hye-Gyeong 한국방재학회 2016 한국방재학회지 Vol.16 No.1