한의학 기반 반려동물용 치료기술 개발 관련 특허 분석

이지혜,김성호,이수은,남현화,박준홍,천진미,서윤수,김보혜,이정민,문창종,김중선,문병철,Lee, Ji Hye,Kim, Sung Ho,Lee, Sueun,Nam, Hyeon-Hwa,Park, Jun Hong,Chun, Jin Mi,Seo, Yun-Soo,Kim, Bohye,Lee, Jeongmin,Moon, Changjong,Kim, Joong Sun,Moon 대한본초학회 2022 大韓本草學會誌 Vol.37 No.6

Objective : In this study, we conducted to analysis the patents about Korean medicine based treatment technology for pet. Methods : We collected the Korean, Japan, USA, China, EU and PCT patent for the Korean medicine-based treatment technology for pet using WIPSON data base registered by October 4, 2020 were selected. Results : Patents for the development of pet Korean medicine-based treatment technology have been constantly applied since the mid-2000s, starting in 1990, with a total of 84 applications. The number of patent applications filed in Korea was the largest, after Japan and China. The detailed composition of the applications reported until now is pharmaceutical compositions for the treatment of pet were the most applied with 39%(33 cases), followed by feed used as stocks for pet at 36%(30 cases). According to the patent application rate by disease, most of applications rate composed to be associated with immunity in 2009 to 2013 with 40% of applications. In 2014 to 2018 43% of patent applications are associated with gastrointestinal/digestive system. In this regard, multiple applications were filed in the order of immunity, digestive system, obesity and urinary system. Conclusion : This study analyzed the trend of 84 patents about Korean medicine-based treatment technology for pet to date to establish the basis for future research and development. There were many applications related to immunity from 2009 to 2013, and since then, related to digestive disease from 2014 to 2018.

액션러닝 기반 온라인 실습이 간호대학생의 자기주도적 학습능력, 학업적 자기효능감과 협업능력에 미치는효과

이지혜,한미라,Lee, Jihye,Han, Mira 국제문화기술진흥원 2022 The Journal of the Convergence on Culture Technolo Vol.8 No.6

The purpose of this study was to identify the effects of online practicum based on action learning on self-directed learning ability, academic self-efficacy, and cooperation ability of nursing students. Similar experimental study of single group pre-post test design was used to investigate the effects of this online class. A total of 47 nursing students who were junior grade from one college participated in this study and self-administered questionnaire was used for data collection. Data were analyzed by frequencies, paired t test using the SPSS/Window 21.0 program. The result of this study showed that the improvement after online practicum based on action learning was significant in self-directed learning ability(t=3.832, p<.001), academic self-efficacy(t=4.258, p<.001), and cooperation ability(t=3.853, p<.001). These findings imply the value of online practicum based on action learning to enhance competency of nursing students. In the future, more studies should be conducted in the same group including control group and blended learning method using action learning to validate the effectiveness.

나의 당뇨 체험기

이지혜,Lee, Ji-Hye 사단법인 한국당뇨협회 2007 당뇨 Vol.208 No.-

말기암환자 가족 간병인의 간병 부담과 관련된 요인

이지혜,박현경,황인철,김효민,고수진,김영성,이용주,최윤선,황선욱,안홍엽,Lee, Jee Hye,Park, Hyun Kyung,Hwang, In Cheol,Kim, Hyo Min,Koh, Su-Jin,Kim, Young Sung,Lee, Yong Joo,Choi, Youn Seon,Hwang, Sun Wook,Ahn, Hong Yup 한국호스피스완화의료학회 2016 한국호스피스.완화의료학회지 Vol.19 No.1

목적: 말기암환자 가족 간병인의 간병 부담을 줄이는 것은 가족뿐 아니라 환자를 위해서도 중요하다. 본 연구에서는 말기암환자 가족 간병인의 간병 부담과 관련된 요인에 대해 살펴보았다. 방법: 국내 7개 기관의 완화의료병동에서 입원치료를 받는 말기암환자의 가족 간병인 289명의 자료를 분석하였다. 간병인이 느끼는 주관적 간병 부담은 암환자 가족 돌봄 경험 평가도구를 사용하였고, 5가지 차원에서 단계적 변수 선정을 사용한 로지스틱 회귀 모형을 통해 유의한 인자를 확인하였다. 결과: 간병부담의 각 차원에서 다양한 인자들과의 관련성이 확인되었다. 감정적 요인은 가장 폭넓은 영향을 미쳤는데, 감정적 스트레스를 가진 군은 그렇지 않은 군에 비해, 생활패턴이 변할 가능성이 2.54배(95% confidence interval, 1.29~5.02), 가족의 협조가 부족할 가능성이 2.27배(1.04~4.97), 그리고 신체적 부담이 커질 가능성이 5.44배(2.50~11.88)였다. 가족기능은 가족의 협조부족을 매우 잘 반영하였으며, 심한 가족기능 장애를 보일 경우 경제적 부담과도 관련이 있었다. 종교를 가진 군과 동반질환이 없는 군에서 오히려 간병 부담이 더 높은 것으로 나타났으며, 간병기간과 하루 중 간병시간은 생활패턴의 변화와 신체적 부담을 유의하게 예측하였다. 직업을 가지고 있거나, 사회적 지지가 부족하거나, 자주 방문하지 못하는 가족 간병인은 낮은 자아 존중감을 보였다. 결론: 본 연구 결과에 의하면, 가족 간병인의 간병 부담을 파악하기 위해서는 그들의 정서상태와 가족기능을 파악하는 것이 도움이 되며, 사회적 지지체계를 포함하여 경제적 부담을 완화시키는 노력이 필요하겠다. Purpose: It is important to alleviate care burden for terminal cancer patients and their families. This study investigated the factors associated with care burden among family caregivers (FCs) of terminally ill cancer patients. Methods: We analyzed data from 289 FCs of terminal cancer patients who were admitted to palliative care units of seven medical centers in Korea. Care burden was assessed using the Korean version of Caregiver Reaction Assessment (CRA) scale which comprises five domains. A multivariate logistic regression model with stepwise variable selection was used to identify factors associated with care burden. Results: Diverse associating factors were identified in each CRA domain. Emotional factors had broad influence on care burden. FCs with emotional distress were more likely to experience changes to their daily routine (adjusted odds ratio (aOR), 2.54; 95% confidence interval (CI), 1.29~5.02), lack of family support (aOR, 2.27; 95% CI, 1.04~4.97) and health issues (aOR, 5.44; 2.50~11.88). Family functionality clearly reflected a lack of support, and severe family dysfunction was linked to financial issues as well. FCs without religion or comorbid conditions felt more burdened. The caregiving duration and daily caregiving hours significantly predicted FCs' lifestyle changes and physical burden. FCs who were employed, had weak social support or could not visit frequently, had a low self-esteem. Conclusion: This study indicates that it is helpful to understand FCs' emotional status and family functions to assess their care burden. Thus, efforts are needed to lessen their financial burden through social support systems.

식코가 남긴 과제

이지혜,Lee, Ji-Hye 대한병원협회 2008 대한병원협회지 Vol.37 No.3

무전해 Ni-P 두께와 Assembly Process가 Solder Ball Joint의 신뢰성에 미치는 영향

이지혜,허석환,정기호,함석진,Lee, Ji-Hye,Huh, Seok-Hwan,Jung, Gi-Ho,Ham, Suk-Jin 대한용접접합학회 2014 대한용접·접합학회지 Vol.32 No.3

The ability of electronic packages and assemblies to resist solder joint failure is becoming a growing concern. This paper reports on a study of high speed shear energy of Sn-4.0wt%Ag-0.5wt%Cu (SAC405) solder with different electroless Ni-P thickness, with $HNO_3$ vapor's status, and with various pre-conditions. A high speed shear testing of solder joints was conducted to find a relationship between the thickness of Ni-P deposit and the brittle fracture in electroless Ni-P deposit/SAC405 solder interconnection. A focused ion beam (FIB) was used to polish the cross sections to reveal details of the microstructure of the fractured pad surface with and without $HNO_3$ vapor treatment. A scanning electron microscopy (SEM) and an energy dispersive x-ray analysis (EDS) confirmed that there were three intermetallic compound (IMC) layers at the SAC405 solder joint interface: $(Ni,Cu)_3Sn_4$ layer, $(Ni,Cu)_2SnP$ layer, and $(Ni,Sn)_3P$ layer. The high speed shear energy of SAC405 solder joint with $3{\mu}m$ Ni-P deposit was found to be lower in pre-condition level#2, compared to that of $6{\mu}m$ Ni-P deposit. Results of focused ion beam and energy dispersive x-ray analysis of the fractured pad surfaces support the suggestion that the brittle fracture of $3{\mu}m$ Ni-P deposit is the result of Ni corrosion in the pre-condition level#2 and the $HNO_3$ vapor treatment.

탄뎀 가스메탈아크 용접의 토치 극간거리에 관한 실험적 연구

이지혜,김일수,정성명,이종표,김영수,박민호,Lee, Ji-Hye,Kim, Ill-Soo,Jung, Seong-Myeong,Lee, Jong-Pyo,Kim, Young-Su,Park, Min-Ho 대한용접접합학회 2012 대한용접·접합학회지 Vol.30 No.6

The tandem welding process is one of the most efficient welding processes widely used in material joining technique such as manufacturing of strong and durable structures. It facilitates high rate of joint filling with little increase in the overall rate of heat input due to the simultaneous deposition from two electrode wires. The two electrodes in tandem welding process helps in high-efficiency and high productive of welding process. In this study a automated tandem welding system is developed to determine the correlation between cathode and anode and compared with current ratio of the two electrode torch. Three different inter-electrode distances were chosen, 25mm, 35mm and 45mm to perform the experiment with three different current ratio. From the experiment results, the current ratio between two torch has a large impact on width, height and depth of penetration. In addition, a stable bead geometry is obtained when inter-electrode distance is 35mm.

Development of science program using astronomical data in the history of Korea

이지혜,신동희,Lee, Ji Hye,Shin, Dong Hee 한국천문학회 2012 天文學會報 Vol.37 No.2

Science we have perceived as genuine science is based on western scientific enterprise, that is, western modern science(WMS). The K-12 science curriculum in Korea absolutely contains WMS content. Elkana(1981) criticized the indifference of comparative science in the field of science, whereas there have been a lot of comparative studies of art, religion, ethics, and politics. Science is the product not only based on 'western' culture but all cultural around the world including Korea. People have consistently observed and tested for such a long period of time all over the world. Traditional science of Korea can be related to multiculturalism, which has become important in many fields. Korea has a lot of great scientific enterprises, such as astronomical instruments of Chosun Dynasty and ancient data of natural phenomenon in Samguk-saki or Samguk-Yusa. It is expected that students will consider them as more 'objective' and 'realistic' things rather than 'artistic' and 'distinguished' things. Astronomy was also very important in the East because they believed sky as king, which results in the development of a lot of astronomical data and instruments in Korean history. In this study, we developed three units of science programs using astronomical enterprises in Korea: 1) Activities with our sundial, Angbuilgu:, 2) data interpretation of natural phenomenon in ancient Korea, 3) experience in Gyeongbokgung Palace. From these programs, we expect that students will develop a profound understanding and take pride in our science.

농작물재해보험 가입 결정요인에 관한 분석 -수도작 농가를 중심으로-

이지혜,송경환,Lee, Ji-Hye,Song, Kyung-Hwan 한국유기농업학회 2015 韓國有機農業學會誌 Vol.23 No.1

This thesis has analyzed the determination factor for the crop insurance of rice focused on paddy rice. The analysis on each farmer has been used with integrated probit model & random effects probit model. It has shown in the analysis result of determination factor for buying the crop insurance of paddy rice farmer through integrated probit model & random effects probit model that the higher age, degree of education, cultivated area, and amount of received insurance money and the lower in a number of family member have revealed the higher possibility to buy the crop insurance in the integrated probit model. While the random effects probit model has shown a higher possibility to buy the crop insurance as the higher age, cultivated area, and amount of received insurance money.

황련해독탕(黃連解毒湯) 열수 추출물의 급성독성 연구

이지혜,음현애,정태호,이윤희,엄영란,임남희,김동선,마진열,Lee, Ji-Hye,Eum, Hyun-Ae,Chung, Tae-Ho,Lee, Yoon-Hee,Um, Young-Ran,Yim, Nam-Hui,Kim, Dong-Seon,Ma, Jin-Yeul 대한한의학방제학회 2010 大韓韓醫學方劑學會誌 Vol.18 No.2

Objective : The objective of this study was to evaluate the single dose oral toxicity of Hwangryundaedok-tang extract in ICR mice. Methods : 0(control group), 1250, 2500 and 5000 mg/kg of Hwangryundaedok-tang extracts were orally administered to 20 male and 20 female ICR mice. After single oral administration of Hwangryundaedok-tang extract to ICR mice, we observed number of the death, clinical signs, changes of body weights for 14 days. After 14 day of Hwangryundaedok-tang extract administration, all mice were sacrificed and major organs were observed. Results : Compared with the control group, we could not find any toxic signs in the mortalities, clinical signs, body weight changes, necropsy findings and hematological values in all treated groups(1250, 2500 and 5000 mg/kg). Conclusions : $LD_{50}$ value of Hwangryundaedok-tang extracts may be over 5000 mg/kg and it may have no side toxic effect to ICR mice.