백선피지부자복합방(白鮮皮地膚子複合方)의 항아토피피부염 효능에 관한 실험적 연구

심부용 ( Boo Yong Sim ),지중구 ( Joong Gu Ji ),이원융 ( Won Yung Lee ),김수정 ( Su Jung Kim ),김효영 ( Hyo Young Kim ),이지영 ( Ji Young Lee ),김동희 ( Dong Hee Kim ) 대전대학교 한의학연구소 2014 혜화의학회지 Vol.22 No.2

In order to investigate the efficacy of BJBB on atopic dermatitis, various immune related factors were studied. The results and conclusions are as follows. Atopic dermatitis symptoms were improved in BJBB treated group and significant decrease in dermatitis index were observed in 13 weeks. ALT, AST and BUN, Cr levels were all with in the normal ranges in BJBB treated group, indicating no induced toxicity. BJBB treated group showed significant decrease in CD4+, CD11b+/Gr-1+ immune cell ratio in dorsal skin by 33% and 62% respectively. BJBB treated group showed significant decrease in the expression of IL-4, IL-5, IL-13 and histamine by 83%, 62%, 53% and 61% respectively. Also the group showed decrease in the transcription of IL-4, IL-5 and IL-13 mRNA in spleen by 41%, 52% and 50% respectively. BJBB treated group showed decrease in the expression of IgE by 57% respectively. The results above indicated that treatment of BJBB improved atopic dermatitis symptoms by immune modulation activity a clinical evidence. thus, BJBB has a potential use as a composition of medicinal plants for treatment against inflammation related disease.

마이크로파 저온진공건조 기술을 이용한 홍삼제조공정 개발 및 제품특성에 관한 연구

이상호(Sang Ho Lee),지중구(Joong Gu Ji) 한국유화학회 2017 한국응용과학기술학회지 Vol.34 No.2

본 연구는 마이크로파 저온진공건조 기술을 이용하여 고효율 인삼개발을 하고자 하였다. 홍삼제조 공정에서 증삼 후 60-70℃에서 24시간 동안 건조하고 다시 40℃에서 72시간동안 건조한 열풍 건조 홍삼과 증삼 후 마이크로파 저온진공건조기에서 900 watt, 2.45 MHz, 50 mmHg 조건으로 5시간동안 건조하고 다시 750 mmHg로 2시간동안 건조한 홍삼으로 조직 관찰, 관능평가, 진세노사이드 및 조사포닌 함량 변화 등을 비교하였다. 그 결과, 마이크로파 저온진공 홍삼은 색도가 밝은 색으로, 표면적은 다공성 조직으로 변화하였으며, 향미를 높이고 쓴 맛을 크게 감소시킴과 동시에 단 맛을 증가시켜 종합적인 선호도를 높였다. 또한, 단시간에 진세노사이드 Rg₁과 Rb₁ 함량을 열풍 건조 홍삼에 비해 1시간대에서 약 6배, 8배가 증가되었으나, Rg₃ 함량에서는 큰 차이가 나타나지 않았다. 마지막으로 조사포닌 함량은 10-20분대부터 크게 증가하여 이후 지속적으로 높은 함량이 나타났다. 이와 같은 결과를 종합해보면, 마이크로파 저온진공홍삼은 열풍 건조 홍삼에 비해 다공성 조직 변화를 통해 단시간에 진세노사이드 및 조사포닌에 대한 추출 수율을 높이고 향미와 식감을 개선시켜 홍삼에 대한 선호도를 높일 수 있음을 확인되었다. The purpose of this study was to develop the high efficiency of ginseng by using microwave low temperature vacuum drying technology. In red ginseng manufacturing processes, the study results compared the hot-air drying red ginseng dried during 24hours in 60-70℃ and redried during 72hours in 40℃ after the steaming ginseng with the red ginseng dried in microwave low temperature vacuum dryer on condition that 900 watt, 2.45 MHz, 50 mmHg during 5 hours and redried during 2 hours on 750 mmHg after the steaming ginseng about observation of tissue, sensory evaluation and a change of ginsenoside and crude saponin content. As a result, the red ginseng in microwave low temperature vacuum was had high brightness, the surface turned into porosity tissue and added more flavor, decreased bitterness highly on the contrary increased sweetness at the same time that elevated the comprehensive preference. Moreover, In a short time, the content of ginsenosides Rg₁ and Rb₁ increased about sixfold, eightfold in one time zone but there were no wide difference in content of Rg₃ as compared to the hot-air drying red ginseng. Finally, content of crude saponin was increased widely at 10-20 minutes and stayed high crude saponin content consistently. Therefore, this result indicated that the red ginseng in microwave low temperature vacuum increased extraction yields of the ginsenosides and crude saponin through a change of porosity tissue and improved flavor and texture compare with the general hot air dried red ginseng in a short time. According to these results, that provided that could increase the preference about red ginseng.

아토피피부염 동물 병태 모델에서 石紫解肌湯의 면역조절작용에 관한 연구

이병웅(Byung Woong Lee),김선빈(Seon Bin Gim),송향희(Hyang Hee Song),지중구(Joong-Gu Ji),박지원(Ji won Bak),김동희(Dong Hee Kim) 한의병리학회 2012 동의생리병리학회지 Vol.26 No.4

In order to evaluate the efficacy of SHT against atopic dermatitis (AD), various immune related cytokines as well as histological comparison were performed in animal models, and the results are described. Clinical skin index of the SHT treated group decreased significantly in weeks 11 and 13, compared to the control group. Also, CD4+ immune cell ratio in the dorsal skin was significantly decreased to 69%, and both epidermal and dermal skin thickness was decreased. Serum IL-4, IL-5, IL-6, IL-13, and TNF-α, which are all important markers of inflammation, were decreased to 64%, 44%, 87%, 48%, and 45%, respectively. The expression of histamine, a chemical transmitter increasingly released during the progression of inflammation, was significantly decreased to 47%. The production of IgE immunoglobulin was significantly decreased to 16% compared to the control group. In conclusion, SHT pacifies the activation of T cells, leading to suppression of both Th2 cytokine overexpression and infiltration of immune cells into skin. As a result, relative thinning of both epidermis and dermis were observed. With the results obtained from in vitro studies, the immune modulatory effect of SHT in AD animal models was experimentally demonstrated. This study should provide solid information to construct EBM and for clinical practice.

한방화장품의 눈가 주름 개선 효과

강신정(Kang, Shin-Jyung),김애정(Kim, Ae-Jung),이명숙(Lee, Myoung-Sook),이연희(Lee, Yeon-Hee),지중구(Ji, Joong-Ku) 한국산학기술학회 2011 한국산학기술학회논문지 Vol.12 No.1

맥문동, 차가버섯, 감초, 흑삼, 백출, 백복령, 당귀, 숙지황, 천궁, 작약의 추출물을 이용한 한방소재로 에센스 와 크림을 제조하여 눈가의 주름개선 효과를 평가하였다. 평균연령 44.8세의 한국인 중년여성 6명을 대상으로 에센스 사용 후 크림 사용으로 매일 2회씩(아침, 저녁), 1cm2당 2mg씩, 4주간 연속 사용하도록 한 다음, 4주 경과 후 눈가 주름의 모사판을 제작하여 영상 분석하였다. 눈꼬리 주름 모사판 영상분석 결과, 에센스와 크림 사용 4주 후 주름 R1 은 3.22±0.85에서 2.38±0.32, R2는 3.08±0.83에서 2.22±0.32, R3는 2.29±0.64에서 2.29±0.64, R4는 0.44±0.14에서 0.44±0.14, R5는 0.98±0.21에서 0.98±0.21로 유의하게 감소하여(P<0.05), 본 시료는 눈가주름개선에 효과 있는 것으로 평가되었다. This study evaluated anti-wrinkle effect for eye using essence and cream containing extract of Liriope platy phyllla, Inonotus obliquus, Glycyrrhiza glabra, black ginseng, Atractylodes japonica, Poria cocos Wolf, Angelica gigas, Rehmanniae Radix Preparata and Cnidii Rhizoma, Paeonia lactiflora. 6 female adults on average at the age of 44.8, applied cream after essence under the normal conditions of use on the crow's feet area, twice a day (in the morning and evening), 2mg/1cm 2 for 4weeks. After 4 weeks, the replica of eye wrinkle was made and analyzed the image. The result was that eye wrinkle was decreased in R1(3.22±0.85 to 2.38±0.32), R2(3.08±0.83 to 2.22±0.32), R3(2.29±0.64 to 2.29±0.64), R4(0.44±0.14 to 0.44±0.14), and R5(0.98±0.21 to 0.98±0.21)(P<0.05). Therefore, oriental medicine cosmetics containing traditional herb medicine may play a role anti-wrinkle for eye.

단재 신채호 교육관 고찰

이지중(Lee Ji-Joong) 한국교육사상학회 (구 한국교육사상연구회) 2007 교육사상연구 Vol.21 No.2

The purpose of this article is to study Dan-Jae, Shin Cha-Ho(丹齋 申采浩, 1880~1936)‘s patriotic educational thought. Basically, he understood education as essential methods to regain national rights and to establish a modernized country. Therefore I'd like to analyze the educational aim that he wanted to set up, the educational contents that he wanted to teach and the trend of thought that influenced the constitution of his educational thought. After which I would like to investigate some educational suggestions to improve today's education into a more desirable condition. The results of the study are summarized as follow. First, he established the aims of education as Sang-mu-kyo-yuk(尙武敎育), which means an education for people which is soldier-like and as Jung-yuk-kyo-yuk(情育敎育), which means an education for loving ones country. Secondly, he wanted to establish the traditional beauty of country, kuk-su(國粹) as the contents of education for Jung-yuk-kyo-yuk(情育敎育). Thirdly, he emphasized the importance of the Korean language and encouraged old books that have emphasized the beauty of Korea. Finally, the trend of thought at that time that influenced constructing his thought greatly was his attitude to reinterpret Confucianism, his inclination towards patriotism, and western modernistic knowledge like the theory of social evolution.

유식삼성설과 훈습의 관계성에 대한 고찰

이지중 ( Lee Ji-joong ) 사단법인 한국교수불자연합회 2020 한국교수불자연합학회지 Vol.26 No.3

This paper examines the relationship between the yoo-sik samseongseol(유식 삼성설; Theory of three types of nature of phenomena classified by the Dharma-character School) and vasana(훈습; hume or imprints), focusing on the vasana of ‘uitaseong(의타성; ‘interdependent existence of things)’. As a result, we could have some conclusions as follows. First, uitaseong(의타성) depends upon vasana(훈습) and yeon-gi(연기). Uitaseong(의타성) is the self-nature of alaya-vijñapti. It is not a self-existing entity, but a result of being bound by a relationship outside oneself. Despite the fact that the essence of consciousness is no-mind, the reason why humans can discern and recognize their own world is because of vasana(훈습) and yeon-gi(연기). Second, the quality of uitaseong(의타성) depends on vasana(훈습). Uitaseong(의타성) has no fixed the self-nature. The essence of alaya-vijñapti is structured differently by vasana(훈습). Therefore we can live in pain through vasana(훈습) of karma and klesa [번뇌, beonnoi] or live in wisdom through munhunseup(문훈습). Finally, the difference in action of the uitaseong(의타성) is also structured differently by vasana(훈습). Even alaya-vijñapti is the basis of the all recognition phenomena of humans, it is structured by unseol vasana(언설훈습), yuboon vasana(유분훈습) and akun vasana as 11 style of uitaseong(의타성). In this way, alaya-vijnana become the seed of world understanding and its function as yeon-gi(연기) will also be able to work.

초기유식의 언어관

이지중 ( Ji Joong Lee ) 사단법인 한국교수불자연합회 2013 한국교수불자연합학회지 Vol.19 No.2

In the early Vijnaptimatrata(No-mind), language is foundation that human understand their life-world by use of. Concerning the reason why human can understand their the life-world, even though it is vijnaptimatrata(No-mind), vijnaanavaadin(唯識學) explains that e-ta-sung(依他性, the nature of causal dependence) as 11 vijnapti phenomenalize into consciousness by the help of language. It means that not only human can be influenced by the power of language itself but there is no relationship between language and beings that exist based on language. However, it does not mean that human knowledges are of no use, which tells we should analyze the relationship between language and beings in our life-world. It can be a positive clue that we would transcend from the closed world into the opened one of wisdom. It is the wisdom we see ourself and understand the other humans and beings itself as well. The understanding the name and form(意言分別) of our knowledge is a very important assignment we should carry out.

선문답의 교육적 생명력 -줄탁동시(쵀啄同時)를 중심으로-

이지중 ( Ji Joong Lee ) 사단법인 한국교수불자연합회 2010 한국교수불자연합학회지 Vol.16 No.1

Jool-Tak means that the student and the teacher go together through the wall of the biased view for having the wisdom of the enlightment. For it, the teacher need to have the student to get the soul-searching what he/ she is as well as to understand what the world is around her/ him. The education do not only exist for achiving the knowledge needed by the industrial society but exist for the knowledge of what I am as well as what the world is. Then, the meanings of Jool-Tak coule give lots of implications for today`s education which concentrates to make people that produce much more knowledge.

창조성에 관한 유식학적 해석

이지중(Lee, Ji-Joong) 창조교육학회 2012 창조교육논총 Vol.14 No.-

창조성이란 이전에 없던 어떤 것을 새로이 만들어 짓는 것이고, 그리고 그 능력을 가능케 하는 태도를 함께 말하는 것이라 볼 수 있다. 이를 유식학의 관점에서 해석하자면, 우선 창조성이란 언어의 힘으로부터 걸림이 없는 자유로움으로부터 발현될 수 있다. 이러한 눈은 우리의 세계이해란 곧 언어가 열어주는 물길에 따라 그것이 우리의 의식의 창에 현상된 것임을 바르게 아는 것에서 출발할 수 있다. 이는 우리의 앎과 언어의 관계성에 관한 적확한 해석의 필요성을 말하는 것이다. 이러한 언어의 본질과 앎의 관계에 관한 적확한 해석을 토대로 우리는 우리의 인식현상의 참 뜻을 알 수 있다. 그리고 그것은 우리 스스로 갖추고 있는 닫힌 세계로부터 열린 세계로의 초월을 뜻하는 것이다. 이렇게 보면 창조성의 발현은 우리의 사유를 제한하는 언어의 힘으로부터의 자유로움과 새로운 언어체계의 구성에서 그 실마리를 찾을 수 있을 것이다. The aim of this study is to interpret the creativity in the view of the doctrine of Vijñaptimãtratã. The creativity is meant to be ability that makes things new which have never existed before and the attitude that makes these abilities possible as well. Interpreting it in the view of the doctrine of Vijñaptimãtratã, the creativity can be revealed in freedom from the shackles of language that has some power to disturb peoples' understanding their world itself. It tells that we should know the relationship between language and things. From the accurate understanding the relationship, we can come to know the essence of our consciousness. It can be a clue that we would transcend from the closed world into the opened one of wisdom. Transcending into the opened world of wisdom stands for our being free in thinking something, which we can call it creativity.

체벌이 남긴 마음의 상처에 관한 몇 가지 사례 분석

이지중 ( Ji Joong Lee ) 한국교육철학학회 2011 교육철학연구 Vol.33 No.2

The aim of this thesis is to analysis some cases of students`s wounded heart by the corporal punishment in school and its effects on their Saramdaum. I have come to some conclusions as belows. First, the corporal punishment has negative effect on the research participants` Saramdaum. We can see it in the cases of death wish, avoiding male, hating teachers or skipping classes. Second, we can confirm that the corporal punishment is not the right way for the ruling principle of the research participants` school life and educational act. Third, the corporal punishments is the very factor to make worse the relations between the research participants and teachers. Fourth, the corporal punishment has a bad effect on making friends among class. Because the corporal punishment often is carried out publicly. Fifth, in case corporal punishment happened in early childhood time as in the elementary or middle school days, it colud affect more seriously on the research participants` Saramdaum. Finally, watching other students` corporal punishment also has a bad influence to cause deep scar to the research participants` mind. It means that a second corporal punishment has the negative effects on students` Saramdaum.