콜라겐 젤과 성장인자 전처치 및 피복재료가 다공성안와삽입물의 섬유혈관증식에 미치는 효과

이준영,김석영,유창국,이무석,이상렬,오중협,김성주.Joon-Young Lee. M.D.. Suk-Young Kim. Ph.D.. Chang-Kook You. Moo-Seok Lee. Sang-Yeul Lee. M.D.. Ph.D.. Jung-Hyub Oh M.D.. Ph.D.. Sung-Joo Kim M.D.. Ph.D. 대한안과학회 2005 대한안과학회지 Vol.46 No.6

Purpose: To determine the effect of bFGF complexed collagen gel, which allows constant release of bFGF along with biodegradation of the collagen gel. The specific study purpose was to determine whether it can accelerate the fibrovascular ingrowth into wrapped HA-coated porous alumina and to verify the safety of new wrapping materials. Synthetic polyester-urethane (Neuropatch?) and lyophilized bovine pericardium (Lyoplant?) were compared to donor sclera for the fibrovascular ingrowth into HA-coated porous alumina. Methods: The experimental and control groups, each consisting of 9 rabbits were wrapped with each wrapping materials (3 rabbits per wrapping material). The experimental group underwent pretreatment of bFGF-collagen gel while the control group did not. The fibrovascular ingrowth was compared at 2 and 4 weeks after implantation. Western blot analysis was conducted at 4 weeks using antibodies against CD141 and laminin. The rate of fibrovascular ingrowth was fastest in orbital implant wrapped with Lyoplant?. Results: Histopathologic examinations at 2 weeks showed no differences in distance and percentage area of fibrovascular ingrowth. Histopathologic examinations at 4 weeks showed that pretreatment of bFGF-collagen gel increased the fibrovascular ingrowth in the experimental group. Western blot analysis on experimental group also showed that the expressions of CD141 and laminin were increased by bFGF-collagen gel, thereby indicating that the fibrovascular proliferations were accelerated by bFGF released from the complex. Conclusions: bFGF-collagen gel increased the rate and degree of fibrovascular growth into hydroxyapatite- coated porous alumina by releasing bFGF as the collagen gel biodegraded. Both Lyoplant? and Neuropatch? were evaluated as safe for substitution of the donor sclera.

성인의 원위 경비골 관절에 발생한 골연골종 - 1예 보고 -

이준영,이광철,Lee, Jun-Young,Lee, Kwang-Chul 대한족부족관절학회 2003 대한족부족관절학회지 Vol.7 No.2

Although osteochondromas are common lesions, osteochondroma accompanying diastasis of the ankle joint in a child or adult is an uncommon condition. No previous cases of distal tibiofibular diastasis caused by an osteochondroma in adult have been reported except in child. The authurs experienced a case of mild distal tibiofibular diastasis secondary to an osteochondroma in a 37-year-old female presented with right ankle pain. Osteochondroma of the distal tibiofibular joint were detected on magnetic resonance imaging (MRI). She was pain-free 4 weeks after excision of the osteochondroma. The patient has remained asymptomatic for 1 years postoperatively. Early excision obviates the need for complex reconstructive surgery to correct ankle deformity later.

경골 천정(pilon) 골절의 최신 치료

이준영,Lee, Jun-Young 대한족부족관절학회 2011 대한족부족관절학회지 Vol.15 No.2

Pilon fractures involving distal tibia remain one of the most difficult therapeutic challenges that confront the orthopedic surgeons because of associated soft tissue injury is common. To introduce and describe the diagnosis, current treatment, results and complications of the pilon fractures. In initial assessment, the correct evaluation of the fracture type through radiographic checkup and examination of the soft tissue envelope is needed to decide appropriate treatment planning of pilon fractures. Even though Ruedi and Allgower reported 74% good and excellent results with primary open reduction and internal fixation, recently the second staged treatment of pilon fractures is preferred to orthopedic traumatologist because of the soft tissue problem is common after primary open reduction and internal fixation. The components of the first stage are focused primarily on stabilization of the soft tissue envelope. If fibula is fractured, fibular open reduction and internal fixation is integral part of initial management for reducing the majority of tibial deformities. Ankle-spanning temporary external fixator is used to restore limb alignment and displaced intraarticular fragments through ligamentotaxis and distraction. And the second stage, definitive open reduction and internal fixation of the tibial component, is undertaken when the soft tissue injury has resolved and no infection sign is seen on pin site of external fixator. The goals of definitive internal fixation should include absolute stability and interfragmentary compression of reduced articular segments, stable fixation of the articular segment to the tibial diaphysis, and restoration of coronal, transverse, and sagittal plane alignments. The location, rigidity, and kinds of the implants are based on each individual fractures. The conventional plate fixation has more advantages in anatomical reduction of intraarticular fractures than locking compression plate. But it has more complications as infection, delayed union and nonunion. The locking compression plate fixation provides greater stability and lesser wound problem than conventional implants. But the locking compression plate remains poorly defined for intraarticular fractures of the distal tibia. Active, active assisted, passive range of motion of the ankle is recommended when postoperative rehabilitation is started. Splinting with the foot in neutral is continued until suture is removed at the 2~3 weeks and weight bearing is delayed for approximately 12 weeks. The recognition of the soft tissue injury has evolved as a critical component of the management of pilon fractures. At this point, the second staged treatment of pilon fractures is good treatment option because of it is designed to promote recovery of the soft tissue envelope in first stage operation and get a good result in definitive reduction and stabilization of the articular surface and axial alignment in second stage operation.

10세 남자 운동선수에서 발생한 아킬레스건 파열을 동반한 종골 골단의 견열 골절: 증례 보고

이준영,박이규,임재환,Lee, Jun Young,Bak, Yi Gyu,Lim, Jae Hwan 대한족부족관절학회 2018 대한족부족관절학회지 Vol.22 No.2

Calcaneal apophysitis is a relatively common disease in young athletes. On the other hand, if not treated properly, it can lead to apophyseal avulsion fracture in rare cases. In the case of apophyseal avulsion fractures, it is often necessary to remove or preserve the bone fragment, which often requires a suture of the Achilles tendon. A 10-year-old badminton athlete visited the outpatients' clinic with pain in both heels from 10 months ago without any trauma history. After conservative therapy, the pain in the left heel was relived but the right heel pain persisted. After 10 months of conservative therapy, the patient visited the outpatients' clinic showing a calcaneal apophyseal avulsion fracture with a total rupture of the Achilles tendon. In the operation room, a bone fragment needed to be removed because of its poor viability and the fragment was too thin for fixation. After removing the bone fragment, the ruptured Achilles tendon was fixed with an anchor system.

가골 신연술을 이용한 제4 단중족증 치료 중 발생한 제4 중족골 골두의 무혈성 괴사(1예 보고)

이준영,조성원,박치형,Lee, Jun-Young,Cho, Sung-Won,Pak, Chi-Hyoung 대한족부족관절학회 2012 대한족부족관절학회지 Vol.16 No.3

Callotasis has been widely used to treat brachymetatarsia. But various complications have been reported. Avascular necrosis of the $4^{th}$ brachymetatarsia treated by callotasis has not been frequently addressed in the literature. We report 1 cases of avascular necrosis of the $4^{th}$ brachymetatarsia treated by callotasis with a review of the literature.

족관절 유합술

이준영,박상하,Lee, Jun Young,Park, Sang-Ha 대한족부족관절학회 2014 대한족부족관절학회지 Vol.18 No.4

Ankle arthrodesis has been used as standard treatment of ankle arthritis unresponsive to conservative treatment. Transfibular approach was used for ankles with severe deformities and minimally invasive arthroscopic ankle arthrodesis was used for patients with mild deformities. Anterior approach may be used when lateral approach couldn't be performed. Tibiotalocalcaneal arthrodesis is standard treatment for coexisting ankle and subtalar arthritis, and modified Blair arthrodesis can be used if the talus body resection is necessary in severe talar necrosis. In serious infection of ankle arthritis, arthrodesis can be performed as staged operation. In cases with low bone density and severe deformities, Charcot arthropathy should be considered.

Maisonneuve 골절에서 수술적 치료의 결과

이준영,하상호,손홍문,이광철,Lee, Jun-Young,Ha, Sang-Ho,Sohn, Hong-Moon,Lee, Kwang-Chul 대한족부족관절학회 2007 대한족부족관절학회지 Vol.11 No.1

Purpose: This study is to analysis the outcome of patient with surgically treated Maisonneuve fracture and find out the factors that might influence the outcome. Material and methods: 20 patients who had surgical treatment due to Maisonneuve fracture between February, 2001 to March, 2005 were studied. The patients were followed for at least 1 year and average follow up period was 25 months. The average age was 41 years, 16 were male and 4 were female. Mechanism of injury according to Rouge-Hansen classification was supination-external rotation. In all cases, percutaneous screw fixation was applied proximal to tibiofibular syndesmosis. The screws were removed after 8 weeks under local anesthesis. Clinical, functional and radiographic results were evaluated. Results: 17 cases (85%) showed satisfying clinical and radiographic results. The mean functional score according to Ankle Scoring System was 91 (83 to 95). Complication occurred in 1 case with underlying systemic disease and 2 cases with initial ankle joint dislocation. Conclusion: Surgical treatment of Maisonneuve fracture showed relatively satisfying result. However, initial injury state and accompanying disease seem to have great effect on the result.

가접부를 고려한 필릿 용접조건의 선정에 관한 연구

이준영,김재웅,김철희,Lee, Jun-Young,Kim, Jae-Woong,Kim, Cheol-Hee 대한용접접합학회 2006 대한용접·접합학회지 Vol.24 No.5

In this study, an experimental method for the selection of optimal welding condition was proposed in the fillet weld which was done over the tack weld. This method used the response surface analysis in which the leg length and the reinforcement height were chosen as the quality variables of the weld bead profile. The overall desirability function, which was combined desirability function fur the two quality variables, was employed as the objective function for getting the optimal welding condition. In the experiments, the target values of the leg length and the reinforcement height are 6m and zero respectively for the horizontal fillet weld of 10mm thickness mild steel. The optimal welding conditions could predict the weld bead profile(leg length and reinforcement height) as 6.00mm and 0.19mm without tack weld and 6.00mm and 0.48mm with tack weld. from a series of welding test, it was revealed that a uniform weld bead can be obtained by adopting the optimal welding condition which was determined according to the method proposed.

Cost Effective Fabrication of a Triboelectric Energy Harvester Using Soft Lithography

이준영,성태훈,여종석,Lee, Jun-Young,Sung, Tae-Hoon,Yeo, Jong-Souk The Korean Vacuum Society 2013 Applied Science and Convergence Technology Vol.22 No.4

에너지 수확은 우리주변에 존재하는 버려지는 에너지를 유용한 전기에너지로 변환하는 기술이다. 마찰전기 소자는 접촉을 통한 정전기를 유도하는 원리로 동력학적 에너지를 전기에너지로 전환하는 소자이다. 본 연구에서는 소프트 식각 기술을 활용하여 제작 단계를 최소화한 마찰전기 에너지 수확소자를 개발하고, 그 전기적 특성을 측정하였다. 마찰전기를 통한 발전은 마이크로패턴을 통해 마이크로 거칠기를 가진 알루미늄 층과 PDMS 층 사이에서 발생한다. 이때 PDMS 층의 마이크로 패턴은 마스크리스 식각을 통해 만들어진 알루미늄 층의 마이크로 패턴을 소프트 식각법으로 바로 본뜨는 방식으로 제작되었다. 본 소자는 2 V와 20 nA의 발전 성능을 나타낸다. Energy harvesting refers to converting ambient energy from our surroundings, which would be otherwise wasted, into useful electrical energy. A triboelectric energy harvester is a self-charged device for harnessing mechanical energy based on a coupled process of contact charging and electrostatic induction. In this research, we demonstrate simple fabrication of prototype triboelectric energy harvester using soft lithography and its electrical characterization. Triboelectric generation occurs between the two micro patterned layers of Au and PDMS. A micro pattern is simply replicated directly from the bottom layer to the top layer using soft-lithography without an extra transfer process. This generator can produce an output voltage of 2 V and output current of 20 nA.

심낭막 절편을 이용한 기관지성형

이준영,강정호,지행옥,Lee, Jun-Yeong,Gang, Jeong-Ho,Ji, Haeng-Ok 대한흉부심장혈관외과학회 1987 Journal of Chest Surgery (J Chest Surg) Vol.20 No.1

For the treatment of bronchial stenosis due to trauma, inflammatory and neoplastic lesion, bronchoplastic procedure in the interest of preservation of lung tissue are relatively new developments in the field of thoracic surgery. We reported on case of bronchoplasty using to pericardial patch for the treatment of bronchial stenosis due to chronic inflammation. The patient was 26 years old female and chief complaint was respiratory difficulty. Bronchogram revealed diffuse stenosis of left main bronchus about 4cm and especially, at just below the carina marked narrowing of lumen and fine serration in the wall. At the time of operation, longitudinal incision was made at left main bronchus about 5cm and reconstructed bronchus using to pericadial patch at membranous compartment of bronchus. The postoperative course was uneventful and post-operative follow up bronchography showed that improvement of bronchoplastic segmented region.