숙지황을 첨가한 쌀 쿠키의 품질특성 및 항산화성

신숙경,민아영,김현정,이수진,심은경,이근종,이보담,김미리,Shin, Suk Kyung,Min, A Young,Kim, Hyun Jeong,Lee, Su Jin,Sim, Eun Kyoung,Lee, Kun Jong,Lee, Bo Dam,Kim, Mee Ree 한국식품조리과학회 2015 한국식품조리과학회지 Vol.31 No.2

The aim of this study was to evaluate the quality characteristics and anti-oxidative activities in the rice cookies with R. glutinosa Preparata (0%, 4%, 8%, 12%) and bean flour (10%). The moisture of cookies was increased depending on amount of R. glutinosa Preparata (RRP). The pH of cookies with RRP was lower than that of the control cookies. Sugar content and reducing sugar of cookies were increased according to the amount of RRP. L-value and b-value of cookies with 12% RRP were lower than the control, whereas a-value was higher than the control. Spread factor of cookies with RRP was lower than the control, and hardness of cookies was increased depending on amount of RRP added. The antioxidant activity such as DPPH radical and hydroxyl radical scavenging activity was significantly increased in the cookies with RRP, compared with that of the control. Also, total phenol content of cookies was increased according to the amount of RRP. In sensory test, cookies with 8% RRP received the highest score for overall preference. As a result, the optimum amount of RRP concentrate to be added in the cookies was found to be 8%.

Euonymus alatus 추출물의 실험적 간 손상 억제

신숙정,이병용,신동근,이정호,Shin, Sook-Jeong,Lee, Byung-Yong,Shin, Dong-Keun,Lee, Jeong-Ho 대한면역학회 2001 Immune Network Vol.1 No.3

Background: A previous study has shown that Euonymus alatus (EA) has an antidotic activities against inflammation, suggesting possibility that EA can exert this beneficial effects to liver injury by an initial protection against drug-induced hepatocyte demage. The present study was undertaken to evaluate the protective effect of EA-extract on experimentally induced hepatitis in ICR mice and to investigate some mechanisms responsible for its action. Methods: Water EA extract was used in this experiments. The mice received i.p. a dose of 700 mg/kg galactosamine (GalN) together with $5{\mu}g/kg$ of endotoxin (LPS), or received i.v. 12 mg/kg of concanavalin A (Con A). EA (4 mg/mouse) was administrated on day -2, -1 and 0 before induction of liver injury. Liver injury was assessed by measurement of serum alanin amino-transferase (SGPT) levels on 9 hr after GaIN.LPS, or 8 hr after con A administration. Results: Treatment with either GaIN or LPS alone did not cause hepatitis. However, simultaneous administration of GalN and LPS to mice resulted in LPS-dose dependent fulminant hepatitis. GaLN/LPS-induced liver injury was reduced when mice were given EA for 3 days before induction. This preventive effect of Ea was more prominent when EA was given by intraperitoneal route rather then by oral route. Pretreatment of EA or dexamethasone inhibited significantly $TNF{\alpha}$ production in GalL/LPS-injured mice. However, EA-treatment did not influence $TNF{\alpha}$-induced hepatitis in GalN-sensitized mice, suggesting that $TNF{\alpha}$ is likely to act as one of final mediators of endotoxin action and the protective effect of EA might be manifested chiefly by inhibition of endotoxin-induced $TNF{\alpha}$ production, not by blocking the $TNF{\alpha}$-action. Injection of Con A into mice evoked remarkable liver injury in a dose dependent fashion. This liver damage was reduced by EA-pretreatment. Dexamethasone significantly reduced both GalL/LPS-induced and Con A-induced liver damages, showing synergism with EA. However, indomethacin reduced only GalN/ LPS-induced hepatitis, not for Con A-induced hepatitis. Conclusion: These results led to the conclusion that EA may be able to contribute at least in part to prevent the drug-induced hepatotoxicity, and that its anti-hepatitis effects might be manifested directly by modulation of endogenous mediators, such as leukotriese D4, $TNF{\alpha}$ and free radical, and indirectly by regulation of immune mediated responses. Also these results suggested that EA could be developed as a potential antidotic agent.

자궁 동정맥기형에서 Transarterial Embolization 실패후 전자궁적출술을 시행한 1 례

신숙진(SJ Shin),이병석(BS Lee),정창진(CJ Jeong),조은정(EJ Cho),차동현(DH Cha),이국(K Lee) 대한산부인과학회 1993 Obstetrics & Gynecology Science Vol.36 No.5

A 29 year old woman who had long history of recurrent uterine bleeding was diagnosed of arteriovenous malformation of uterus by ultrasonogram and angiogram. In our case report, we tried transarterial embolization 2 times for preservation of reproductive capability. But failure of embolization due to recanalization and new collateral arteriovenous malformation formation, the patient was taken total abdominal hysterectomy.

자궁동정맥기형의 임상경험

이병석(BS Lee),신숙진(SJ Shin),이장호(JH Lee),민혜원(HW Min),이윤호(YH Lee),이국(K Lee),김동익(DI Kim) 대한산부인과학회 1994 Obstetrics & Gynecology Science Vol.37 No.9

We experienced 4 clinical cases which had been diagnosed of uterine arteriovenous malformation by Doppler ultrasonogram and pelvic angiogram. In all patients, trasarterial emolization was performed as first choice of treatment modality. Among them, two cases have failed. However, another two patients conceived after the successful transarterial embolization. Therefore, we concluded Doppler ultrasonogram si a useful diagnostic method in patients with arteriovenous malformation. And trasarterial embolization is effective as a first choice of treatment in patients who desire to preserve fertility.

의료의 질 평가 우선순위 설정

신숙연 ( Suk Youn Shin ),박춘선 ( Choon Seon Park ),김선민 ( Sun Min Kim ),김남순 ( Nam Soon Kim ),이상일 ( Sang Il Lee ) 한국보건행정학회 2009 보건행정학회지 Vol.19 No.3

Objectives: To identify target areas and set priorities among those areas identified for national quality evaluation. Methods: Target areas were identified from: i) analysis of the national health insurance claims data, mortality and prevalence data ii) various group surveys, including representatives from 22 medical specialty associations, 19 physician associations, QI staffs in hospital, civil organizations, and commissioners of Health Insurance Review and Assessment Service(HIRA) ⅲ) literature reviews and RAM(RAND/UCLA appropriateness method). The priority areas for national quality evaluation represented the full spectrum of health care and the entire life span. The criteria for selecting the priority areas were impact, improvability, and measurability. The priority areas were divided into three categories: short-term, mid-term, long-term. Results: Based on the group surveys and the data analysis, 46 candidates were selected as quality evaluation priority areas. 13 areas were selected as having a short-term priority areas: tuberculosis, community acquired pneumonia, stroke, ischaemic heart disease, diabetes, hypertension, chronic lower respiratory disease(asthma, chronic obstructive pulmonary disease), intensive care unit, emergency room, nosocomial infection, use of antibiotics, multiple medication and renal failure. This results suggested that we need to enlarge the target priority areas to the chronic diseases in short-term. Conclusions: The priority areas identified from the study will assist healthcare quality associated institutions as well as HIRA in selecting quality evaluation areas. It is required to develope and implement strategies for improving the quality of care within the next 5 years.

객체지향 설계에서 정형명세를 이용한 컴포넌트 설계로의 변환 기법

신숙경(Suk Kyung Shin),이종국(Jong Kook Lee),김수동(Soo Dong Kim) 한국정보과학회 2004 정보과학회논문지 : 소프트웨어 및 응용 Vol.31 No.7

재사용성과 확장성을 높이는 객체지향 개발이 보편화 되면서 새로운 소프트웨어를 개발할 경우 기 개발되어 검증된 객체지향 산출물을 재사용함으로써 개발기간을 단축하고 품질을 향상할 수 있다. 이렇게 성능이 검증된 기 개발된 객체지향 산출물을 이용하여 컴포넌트 기반 모델로 변환하면 짧은 기간에 고품질의 컴포넌트 기반 시스템을 구축할 수 있다. 본 논문에서는 이미 개발되어 있는 객체지향 설계 모델을 이용하여 컴포넌트 기반 설계로 변환하되 변환의 정확성을 위해 정형명세 기법을 사용한다. 컴포넌트 기반 설계를 정형명세하기 위해 컴포넌트 정형명세 언어를 정의한다. 그리고 객체지향 설계의 정적, 동적, 기능적 측면을 정형명세 언어 Object-Z를 사용하여 정형명세하는 기법을 제시한 후, 객체지향 정형명세를 컴포넌트 정형명세로 변환하는 기법을 제시한다. 사례연구는 제시된 변환 기법을 적용하여 객체지향 정형명세가 컴포넌트 기반 정형명세로의 변환과정을 설명한다. As object-oriented development technology that increases extensibility and reusability has been widely spread, it can shorten development period and enhance quality by reusing verified object-oriented artifacts. Thus we can construct high quality component-based system at short time transforming component-based model using verified object-oriented artifacts. In this paper, we propose techniques to transform available object-oriented design model into component-based model using formal specification techniques in order to increase accuracy of transformation. First, formal specification language for component is defined for formal specification of component-based design. And, techniques for formal specification of object-oriented design using Object-Z, a formal specification language, is proposed in structural, functional, and dynamic aspects. Next, we present techniques for transforming formal specification of object-oriented design into formal specification of component-based design. Through a case study we apply the proposed transformation techniques and show the transformation process of object-oriented formal specification into component-based formal specification.

Component - Z : Object - Z를 확장한 컴포넌트 정형 명세 언어

이종국(Jong Kook Lee),신숙경(Suk Kyung Shin),김수동(Soo Dong Kim) 한국정보과학회 2004 정보과학회논문지 : 소프트웨어 및 응용 Vol.31 No.5

컴포넌트 기반 소프트웨어 공학(CBSE)은 재사용 가능한 컴포넌트를 조립하여 시스템을 개발하는 방법이다. CBSE는 소프트웨어 개발 비용과 기간을 단축할 수 있는 새로운 패러다임으로 평가되고 있다. 정형 명세를 사용하면 컴포넌트 구성 요소들 사이의 일관성과 정확성을 판단할 수 있기 때문에 컴포넌트 설계의 품질을 높일 수 있다. 현재까지 제안된 컴포넌트 정형 명세 언어들은 인터페이스 간의 계약, 컴포넌트의 구조적인 측면과 동적인 측면, 컴포넌트 기반 시스템, 컴포넌트 간의 결합, 가변성 중 일부만을 명세에 반영한다. 따라서 지금까지 발표된 정형 명세 언어를 컴포넌트 설계 과정의 모든 단계에서 사용하는 것은 적절치 않다. 본 논문에서는 컴포넌트 정형 명세 언어인 Component-Z를 제안한다. Component-Z는 Object-Z를 확장하여 컴포넌트 명세를 위한 새로운 표기법을 추가하고 의미론을 확장한다. Component-Z를 사용하여 인터페이스, 컴포넌트 내부 구조, 컴포넌트 내부 워크플로우와 인터페이스간의 워크플로우를 명세할 수 있다. 또한 가변점(variation point), 가변치(variant), customization 인터페이스를 사용하여 가변성을 명세할 수 있다. 인터페이스와 컴포넌트 사이의 관계는 매핑 스키마(mapping schema)를 사용하여 정의한다. 또한 병렬 연산자(parallel operator)를 사용하여 컴포넌트 간의 결합을 명세할 수 있고 컴포넌트 기반 시스템을 명세하여 컴포넌트가 배포된 상황을 표현할 수 있다. 따라서 본 논문에서 제안된 정형 명세 언어를 사용하여 컴포넌트 설계에 필요한 모든 요소를 표현 할 수 있다. 사례연구에서는 은행 계좌 관리 시스템을 명세하여 Component-Z가 컴포넌트 설계의 전 단계에서 사용될 수 있음을 보인다. Component-based software engineering (CBSE) composes reusable components and develops applications with the components. CBSE is admitted to be a new paradigm that reduces the costs and times to develop software systems. The high quality of component designs can be assured if the consistency and correctness among the elements of a component are verified with formal specifications. Current formal languages for components include only some parts of contracts between interfaces, structural aspects and behavioral aspects of component, component-based system, component composition and variability. Therefore, it is not adequate to use current formal languages in all steps of a component design process. In this paper, we suggest a formal language to specify component designs Component-Z. Component-Z extends Object-Z, adds new notations to specify components. It can be possible to specify interfaces, the inner structure of a component, inner workflows, and workflows among interfaces with Component-Z. In addition, Component-Z provides the notations and semantics to specify variability with variation points, variants and required interfaces. The relation between interfaces and components is defined with mapping schemas. Parallel operator is used to specify component composition. It can be possible to describe deployed components with the specifications of component-based systems. Therefore, the formal specification language proposed in this paper can represent all elements to design components. In the case study, we specify an account management system in a bank so that we show that Component-Z can be used in all steps of component design.

창의적·도전적 융합연구 생태계 구축을 위한 기초융합연구 지원체계 수립에 관한 연구

박귀순(Kwisun Park),신숙경(Suk Kyung Shin),송영동(Young Dong Song),이성종(Sung Jong Lee),이은규(Eunkyu Lee),차은종(Eun Jong Cha) 한국콘텐츠학회 2013 한국콘텐츠학회논문지 Vol.13 No.12

한국연구재단은 이공분야와 인문사회분야 간 통합 연구를 포함한 융합연구 생태계 구축으로 창의적이고 도전적인 연구를 중점적으로 지원하고자 한다. 이에 기초연구사업의 융합연구를 활성화하고 실질적인 융합연구를 발굴하기 위한 전략을 도출하고 창의적·도전적 융합연구 지원체계 구축을 골자로 하는 ‘융합연구사업추진체계’를 수립하였다. 사업추진체계는 연구분야 중심의 지원분야 재설정, 문제중심융합 신설, 신청자격 확대, ‘융합연구 우수성 평가’ 신설, 최소 융합성 지표 및 가이드라인 도출로 구성되었다. 동 사업추진체계 적용 전 약 38%였던 복수 연구분야분류 지정 경향이 적용 후 98% 이상으로 급증하여 거시적 분야분류 간 융합연구 지원이라는 근본적인 목적을 달성할 수 있는 가능성을 높였다. 선정여부와 융합연구 평가프로세스 간 회귀분석 및 피어슨 상관 분석 결과에 근거하여 평가 단계별 배점제에서 다음 단계 추천 방식으로 평가프로세스를 개선하였다. 또한 연구계획서 양식, 분야 지정 방식 개선안을 도출하여 2013년에 확대적용하였다. National Research Foundation of Korea (NRF) provides underpinning to boost international competitiveness in convergence research including research amalgamating Science and Engineering with Humanities and Social Sciences. Division of Electrical Engineering, Information Sciences and Convergence Research recategorized a scientific and engineering array of convergence research in basic sciences and reformed a Convergence Research Support Framework in 2012. The test case was thoroughly analyzed and reviewed for successful application in the 2013 mid-career researcher program. The core of convergence research-specific review process is ‘Suitability Review’ that is performed by the ‘Suitability Review Committee for Convergence Research’ and ‘Merit Review’ that is conducted as a conventional peer review. As a good result of the pilot program, prior allocation of budget for convergence research was decided to the 2013 Core Research Program and the modified convergence Research Support Framework was extensively applied in the ‘2013 Implementation Plan for Basic Research Program in Science and Engineering.’

쇼핑카트 도난 방지 및 사용자 편의성 향상을 위한 전자식 잠금장치 시스템

박성진(Sung-Jin Park),신숙인(Sook-In Shin),유기상(Ki-Sang Lyu),이주학(Ju-Hack Lee),김시경(Si-Kyung Kim) 한국정보기술학회 2024 Proceedings of KIIT Conference Vol.2024 No.5

한국고대학회 2003년 춘계 학술회의 토론요지 : 토론 ; 한국 선사시대의 생업과 문화

하문식 ( Moon Sig Ha ),신숙정 ( In Soo Ha ),하인수 ( Sook Chung Shin ),이준정 ( June Jeong Lee ) 한국고대학회 2003 先史와 古代 Vol.18 No.-