RISS 학술연구정보서비스

검색
다국어 입력

http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.

변환된 중국어를 복사하여 사용하시면 됩니다.

예시)
  • 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
  • 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
닫기
    인기검색어 순위 펼치기

    RISS 인기검색어

      검색결과 좁혀 보기

      선택해제

      오늘 본 자료

      • 오늘 본 자료가 없습니다.
      더보기
      • 무료
      • 기관 내 무료
      • 유료
      • SCIESCOPUSKCI등재

        배아줄기세포에 의한 영양세포의 지방 분화

        이순례 ( Sun Ray Lee ),박현숙 ( Hyun Sook Park ) 한국조직공학·재생의학회 2010 조직공학과 재생의학 Vol.7 No.1

        Human embryonic stem(hES) cells have generally been cultured on mouse embryonic fibroblast feeder cells. Paracrine factors from feeder cells have drawn much attention in their relation to the maintenance of selfrenewal and pluripotency of hES cells. There has however been no attention on factors from hES cells and their effects on feeder cells. In the present study, we examined the effect of hES cells on feeder cells, mouse embryonic fibroblasts, human mesenchymal stem cells and human skin fibroblasts, in indirect co-culture system using porous membrane. We observed lipid droplet formation in feeder cells as early as 2 days after co-culture and lipid vacuole matured with time in the influence of hESCs. Only with hES-conditioned medium adipogeneisis of feeder cells occurred but co-culture with hES cells dramatically increased adipogenesis of feeder cells. This implied adipogenesis of feeder cells occurred via paracrine communication between hES cells and feeder cells. Further investigation on how adipogenesis of feeder cells affects the niche of human embryonic stem cells is required.

      연관 검색어 추천

      이 검색어로 많이 본 자료

      활용도 높은 자료

      해외이동버튼