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      • KCI등재

        잘토프로펜 유발 Kounis 증후군 1례

        이성유,성원영,이장영,서상원,이원석 대한임상독성학회 2019 대한임상독성학회지 Vol.17 No.1

        Kounis syndrome is defined as the occurrence of acute coronary syndrome associated with vasoactive mediators, such as histamines in the setting of hypersensitivity and allergic reactions or anaphylactic insults. The condition can be caused by various drugs, foods, or environmental factors that cause allergic reactions. A 35-year-old male visited the emergency room with anaphylaxis accompanied by chest pain approximately 20 minutes after taking zaltoprofen, a nonsteroidal anti-inflammatory drug. After acute treatment for the anaphylaxis, the patient was stabilized and all symptoms disappeared, but the ischemic changes in the electrocardiogram and elevation of the cardiac enzymes were observed. The emergency cardiac angiography and echocardiography were all normal. The allergic reaction of this patient to zaltoprofen was believed to cause a temporary coronary arterial vasospasm, inducing Type 1 Kounis syndrome. Thus far, there have been case reports of Kounis syndrome caused by a range of nonsteroidal antiinflammatory drugs, but there are no reports of the condition being caused by zaltoprofen. According to the pathophysiology, both cardiac and allergic symptoms must be solved simultaneously, so rapid treatment and diagnosis are needed. Doctors treating acute allergic reactions and anaphylaxis patients must check the cardiovascular symptoms thoroughly and consider the possibility of Kounis syndrome.

      • KCI등재

        로듐 재자원화의 경제적 및 환경적 효과 분석

        이성유,신가영,김두환,황용우,강홍윤,홍성민,김다연 한국자원리싸이클링학회 2023 資源 리싸이클링 Vol.32 No.3

        본 연구에서는 비촉매분야에서 사용된 로듐의 재자원화 시, 경제적 및 환경적 효과를 분석하였다. 분석방법으로, 경제적 효과 분석은비용편익분석과 자원절감효과분석을 적용하였으며, 환경적 효과 분석은 전과정평가를 적용하였다. 연구결과, 경제적 측면에서 B/C 값은1.28로 사업성이 있는 것으로 나타났으며, 비용절감은 재자원화 로듐 1 g 기준으로 237,000원로 나타나 2025년 로듐 재자원화량 71.7억원으로 나타났다. 환경적 효과는 로듐 1 kg 기준의 재자원화 시와 해외매각 시에 대해 온실가스 배출량을 비교하였다. 산정 결과, 로듐 1 kg 기준으로 재자원화 시 온실가스 배출량은 65 kg CO2eq./kg-Rh, 해외매각 시 28,800 kg CO2eq.으로 나타나, 99.8%가 저감되었다. 본연구결과는 비촉매분야에서 사용되는 로듐의 재자원화 시 경제적 및 환경적 효과 분석을 통해 자원이 부족한 우리나라에서 로듐 재자원화가 필요하다는 것을 제시할 수 있었다.

      • KCI등재

        응급의료센터에 내원하는 일차 두통 환자의 진료 프로토콜 변화가 미치는 영향

        이성유,서상원,이장영,이원석,성원영 대한응급의학회 2019 大韓應急醫學會誌 Vol.30 No.6

        Objective: University hospitals nationwide are experiencing a shortage of neurology residents and excessive workloads; new measures are required because a lack of neurologists in the emergency department (ED) leads to ED overcrowding. This study examined the effects of emergency medicine doctors taking over the role of neurologists in the treatment of primary headache patients visiting the ED. Methods: A study group of primary headache patients, who visited a single university hospital ED between 1 June and 31 October 2017 and were treated by an emergency medical doctor, was selected. The control group consisted of patients who met the same conditions as the study group and visited the ED during the same period in 2016 but were treated by a neurologist. The following variables between the two groups were compared: length of stay in the ED, medical expenses in the ED, and the time taken to decide on neuroimaging tests. Results: This study was conducted on 300 patients in the control group and 94 patients in the study group. The study group showed a shorter time to decide on neuroimaging tests (64.4%, 95% confidence interval [CI], P<0.001), shorter length of stay in the ED (15.2%, 95% CI, P<0.001), and lower medical expenses (12.8%, 95% CI, P=0.011). Conclusion: When emergency medicine doctors take over the neurologic medical care of primary headache patients in ED, it can be expected to reduce ED overcrowding and medical expenses.

      • KCI등재후보

        명주매물고둥에 의한 테트라민 중독

        이성유,이장영,이원석,성원영,서상원 대한임상독성학회 2017 대한임상독성학회지 Vol.15 No.1

        Even though Neptunea contricta appears similar to Batilus cornutus and Rapana venosa, they are different in tetramine content which inhibits the neuronal calcium channel. Therefore, mistaking Neptunea contricta for Batilus cornutus or Rapana venosa, can result in the occurrence of toxic symptoms. Three patients developed nausea, epigastric pain, chest pain, dizziness, blurred vision, dyspnea, hypertension and tachycardia after eating Neptunea contricta. Moreover, consumption of one only piece was sufficient to cause symptoms because each Neptunea contricta has 17.3 mg of tetramine. Accordingly, care should be taken when patients are consuming more than 5 pieces because toxic symptoms such as dyspnea can occur. Moreover, correct species identification is important because the quantity of tetramine varies among sea snail species. Finally, it is important to educate people to remove the salivary glands completely before consuming Neptunea contricta.

      • KCI등재

        도금폐촉매액내 팔라듐 재자원화에 따른 자원 및 온실가스 감축량 분석

        신가영,이성유,강홍윤,Shin, Ka-Young,Lee, Seong-You,Kang, Hong-Yoon 한국자원리싸이클링학회 2021 資源 리싸이클링 Vol.30 No.3

        Palladium present in colloidal-type plated spent catalyst solution that is used in electroless plating process has not been recovered but discharged as wastewater so far. Recyclig of paladium in colloidal-type plated spent catalyst solution is achieved with this study. This study presents the estimation of resource consumption and GHG emissions during the recycling and disposal of palladium in the plated spent catalyst solution using life cycle assessment. The reduction of resources and GHG are also estimated. Based on the palladium amount of 1 kg during disposal, the GHG emission amount was estimated to be 9.67E+03 kgCO<sub>2</sub>eq., and the amount of resource consumption was 3.94E+01 kgSb-eq. However, GHG emission was 1.96E+03 kgCO<sub>2</sub>eq., and the amount of resource consumption was 1.54E+01 kgSb-eq. during recycling. Considering the major substances affecting GHG emissions and amount of resource consumption, CO<sub>2</sub> was found to significantly affect GHG emissions, accounting for 91.42% in disposal and 98.37% in recycling. The major substance affecting the amount of resource consumption was hard coal, which accounted for 40.63% in disposal and 60.73% in recycling. Upon recycling 1 kg palladium, 8,967.17 kgCO<sub>2</sub>eq. of greenhouse gas emission was reduced, while the resource consumption was reduced to 10.10 kg Sb-eq. In addition, the direct palladium resource reduction rate due to palladium recycling was 50%.

      • KCI등재

        폐도금액내 유가금속(Ag) 회수 공정에 대한 전과정 환경성 분석

        김다연,이성유,황용우,권택관 한국자원리싸이클링학회 2023 資源 리싸이클링 Vol.32 No.2

        우리나라는 2018년 기준 전기전자 분야에서 은 수요는 249백만 톤으로 조사되었으며, 태양광 모듈용으로는 81백만 톤으로 조사되었다. 현재 태양광 모듈 설치의 급증으로 해당 분야의 은 사용량 또한 증가하고 있는 추세이다. 그러나 우리나라의 금속자원 및 부존량은 소비량 대비 부족한 실정이며, 금속자원 중 은광의 국내 자급률은 2021년 기준 약 2.2%로 매우 낮은 상황으로 조사되어 이를 개선하기 위해금속산업에서 발생하는 폐도금액내 함유되어 있는 유가금속 자원회수기술을 통한 재활용이 필요하다고 판단된다. 따라서, 본 연구에서는 전과정평가를 통해 폐도금액 내 유가금속 회수공정 개선에 따른 영향평가 결과를 비교 분석하고자 하였다. 그 결과, 개선을 통해 GWP 및 ADP는 각각 약 49% 및 67% 저감되는 것으로 나타났다. 그 중, 전기 및 상수의 GWP는 각각 98% 및 93% 저감되는 것으로 나타나 에너지 소비 최소화에 크게 기여하는 것으로 나타났다. 따라서, 재자원화 기술의 발전이 화학물질 및 에너지의 사용 절감할 수 있으며, 이를통해 도시광산산업에서 자원생산성을 향상시킬 수 있을 것으로 판단된다.

      • KCI등재

        물질흐름원가회계 및 전과정평가 기법을 활용한 팔라듐 재자원화 공정의 경제성 및 환경성분석

        신가영,이성유,황용우,강홍윤,권택관 한국폐기물자원순환학회 2023 한국폐기물자원순환학회지 Vol.40 No.2

        In this study, economic and environmental effects were analyzed by linking material flow cost accounting (MFCA) and life cycle assessment (LCA) methodologies to the process of recycling palladium in a plated spent catalyst solution. Based on an MFCA analysis of recycling 1 kg of palladium, the results indicated that the positive product cost accounted for 82%, whereas 18% was the negative product cost due to material loss, resulting in a total of approximately KRW 139 million. The cost by mass factor indicated that the material cost, including the expenses for catalysts and chemicals, was the highest (57%), followed by the system cost, such as labor and maintenance costs (32%), and the waste management cost (10%). In addition, greenhouse gas (GHG) emissions of 1.97E+03 kgCO2eq were estimated as output cost by using the emission permit in the Korean emission trading system (K-ETS) market, which is equivalent to KRW 50,922. Although this additional output cost on waste management cost was insignificant when 1 kg of Palladium was recycled, this effect would be significant in the future when the amount of recycling increases. Additionally, if the output cost of GHG emissions is applied to the controlled entities under the K-ETS, the effect on waste management costs will be significant.

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