女貞子와 ?寄生이 난소적출로 유발된 흰쥐의 골다공증 치료효과에 미치는 영향

이상윤(Sangyun Lee),서부일(Buil Seo),박지하(Jiha Park),노성수(Seongsoo Roh),김대준(Daejun Kim) 한국한의학연구원 2011 한국한의학연구원논문집 Vol.17 No.1

Objectives : The present study had been undertaken to investigate the effects of Ligustri Lucidi Fructus Extract and Vici Herba Extract on treatment of osteoporosis in ovariectomized rats. Method : In this experiment, the rats were ovariectomized. Rats were individually administered by water extract from Ligustri Lucidi Fructus or Vici Herba(dose:1㎖/100g, 2times/day). The levels of bone mineral density, serum components, urinary components, bony components, body weight and uterus weight were measured. Results : The levels of spinal and femoral bone mineral density(BMD) were significantly increased in comparison with OVX group at 8 weeks after administration in Vici Herba group. The levels of serum osteocalcin showed significant decrease in comparison with OVX group at 4 weeks after administration in Ligustri Lucidi Fructus and Vici Herba group. The levels of serum ALP and phosphorus showed significant decrease in comparison with OVX group at 4, 8 weeks in after administration in Ligustri Lucidi Fructus and Vici Herba group. The levels of urinary deoxypyridinoline showed significant decrease in comparison with OVX group in Ligustri Lucidi Fructus group. The levels of fibula-tibial ash weight showed significant increase in comparison with OVX group after administration in Ligustri Lucidi Fructus group. The levels of body weight were significantly decreased in comparison with OVX group at 4 weeks after administration in Ligustri Lucidi Fructus group and at 4, 8 weeks after administration in Vici Herba group. The levels of uterus weight were not significantly increased in comparison with OVX group in Ligustri Lucidi Fructus and Vici Herba group. Conclusion : Reviewing these experimetal results, it appeared that Ligustri Lucidi Fructus and Vici Herba had efficacy on treatment of osteoporosis.

감기환자의 구강에서 분리된 Streptoccous pneumoniae 59에 대한 관계부자이중탕(官桂附子理中湯)의 효과

이상윤 ( Sang Yun Lee ),서부일 ( Bu Il Seo ),박지하 ( Ji Ha Park ),노성수 ( Seong Soo Roh ),이은숙 ( Eun Sook Lee ),김용현 ( Yong Hyun Kim ) 대한본초학회 2009 大韓本草學會誌 Vol.24 No.1

Objectives: I want to examine the antimicrobial activity of Gwankeibujalijung-tang against Streptococcus pneumoniae 59 isolated from the mouth of a common cold patient. Methods: Antimicrobial activity was assayed through the hot water extract from Gwankeibujalijung-tang against Streptococcus pneumoniae 59 isolated from the mouth of a common cold patient. Results: The size of inhibition zone of Gwankeibujalijung-tang extract was 9.83±0.11 ㎜. The optimal pH and temperature for the growth of isolated Streptococcus pneumoniae 59 were 7.0 and 37℃, respectively. The minimum inhibitory concentration of Gwankeibujalijung-tang extract was 12 ㎕and the antimicrobial activity of Gwankeibujalijung-tang extract was not destroyed by the heat (121℃ for 15 min) and not affected by pH. Conclusions: Reviewing this experimental result, it appeared that Gwankeibujalijung-tang had efficacy against Streptococcus pneumoniae 59 isolated from the mouth of a common cold patient.

유동상 침탄시 저탄소 합금강의 침탄능에 미치는 Ni 함량 및 분위기 가스압력의 영향

노용식,김영희,이상윤 ( Y . S . Roh,Y . H . Kim,S . Y . Lee ) 한국열처리공학회 1990 熱處理工學會誌 Vol.3 No.3

This study has been conducted to establish the carburizing characteristics of low carbon alloy steels with varying amount of Ni element gas-carburized for 2hours at 930℃ in an atmosphere of 94% N₂-6% C₃H_8 gas mixture with some changes in gas pressure passing throgh the diffusion plate in the fluidized-bed furnace. The results obtained from the experiment are as followes : (l) Optical micrograph has shown that the carburized layer consists of retained austenite and plate martensite and that retained austenite increases as the pressure of gas mixture passing through the diffusion plate as well as Ni content increase. (2) Chemical analysis has shown that carbon potential increases and carburizability is also improved due to a less degree of fluidization as the pressures of gas mixtures passing through the diffusion plate increase, resulting in, however, a severe formation of soot, and the gas pressure is necessarily regulated. (3) It has been revealed that carbon concentration hardness values at a given distance measured from the surface within the carburized case. Increase with increasing the pressure of gas mixtures passing through the diffusion plate and decrease with increasing Ni content. (4) The effective case depth has been shown to almost linearly increase as the pressure of gas mixtures passing through the diffusion plate is increased and to decrease with increasing Ni content.

복합열처리된 열간 가공용 금형공구강의 기계적 성질 및 열처리특성에 관한 연구

백성돈,노용식,최문성,최진원,이상윤 ( S . D . Beak,Y . S . Roh,M . S . Choi,J . W . Choi,S . Y .Lee ) 한국열처리공학회 1989 熱處理工學會誌 Vol.2 No.4

The effect of gas mixing ratios during gas nitrocarburizing treatment on the formation of compound layer and the mechanical properties has been studied for hot work tool steel by using a combined heat treating technique. The thickness of compound and diffusion layers has been shown to grow as a parabolic relation with increasing the amount of ammonia at a given flow quantity of CO₂gas. The compound layer consists mainly of ε-Fe₃(C, N) with small amounts of γ`-Fe₄N and α-Fe. The combined heat treated hot work tool steel has shown that the thickness of compound layer increases with increasing nitrocarburizing time, but the rate of growth slows down as gas nitrocarburizing time goes more than two hours. Tensile properties have given a remarkable improvement. In particular, the wear resistance of combined heat treated hot work tool steel has exhibited an improvement of about 165% greater than that obtained from conventional quenching and multi-tempering treatments.

질소-프로판-공기분위기에서 저탄소 합금강의 침탄시 내부산화 특성에 미치는 가스조성의 영향

노용식,김성만,김영희,김한군,이상윤 ( Y . S . Roh,S . M . Kim,Y . H . Kim,H . K . Kim,S . Y . Lee ) 한국열처리공학회 1991 熱處理工學會誌 Vol.4 No.4

This study has been performed to investigate into the internal oxidation characteristics of low carbon steel with respect to the added amount of air in nitrogen-propane atmosphere after gas carburizing for various times at 930℃. The results obtained from the experiment are as follows ; (1) Optical micrographs have shown that the internal oxidation is unlikely to occur in the gas atmosphere without air and that oxidized zone in the outer surface layer is formed in the gas atmosphere with air revealing that the depth of oxidized zone increases with increasing the added amount of air. (2) The formation of internally oxidized zone in the outer surface layer has been found to be inhibited as Ni content increases, i, e, the amount of alloying element increases. (3) The depth of oxidation has been measured to increase with almost parabolically gas carburizing time of up to 6 hours.

플라즈마 질화처리된 중탄소합금강의 내마모특성에 관한 연구

조효석,노용식,신호강,이상윤 ( H . S . Cho,Y . S . Roh,H . K . Shin,S . Y . Lee ) 한국열처리공학회 1992 熱處理工學會誌 Vol.5 No.4

This study has been performed to investigate into some effects of temperature, gas mixing ratio and time on the optical microstructure, hardness and wear characteristics of medium carbon alloy steel treated by plasma nitriding. The results obtained from the experiment are summarized as follows : (1) Optical micrographs of AISI 4140 steel plasma-nitrided by the double stage technique have revealed that the nitrided layer is composed of the compound layer and the diffusion layer. The variation in temperature at the first stage gives effects, on the formation of compound layer and the growth rate is shown to be relatively fast at 460℃. (2) The thickness of compound layer has been found to increase with increasing nitrogen percentage in the gas mixture and the holding time. It is therefore recommended that a shorter holding time and a lower nitrogen percentage are more effective to produce a tougher compound layer and a diffusion layer only. (3) X-ray diffraction analysis for AISI 4140 steel has shown that the compound layer consist of γ`-Fe₄N and α-Fe and that tough compound layer diffustion layer only can be obtained by the double stage plasmanitriding process. (4) There is also a tendency that the total hardened layer depth increases with increasing temperature, time and nitrogen percentage in the first stage during the double stage plasma nitriding. (5) The wear resistance of plasma nitrided specimens has been found thobe considerably increased compared to the untreated specimens and the amount of increment has appeared to increase further with increasing nitriding temperature, holding time and notrogen percentage of gas mixture in the first stage treatment.