새 敎育風土 造成과 古典 읽기

李尙烈 국어교육학회 1973 국어교육연구 Vol.5 No.1

Hospital-Based Korean Diabetes Prevention Study: A Prospective, Multi-Center, Randomized, Open-Label Controlled Study

이상열,전숙,안규정,우정택,the Korean Diabetes Prevention Study Investigators 대한당뇨병학회 2019 Diabetes and Metabolism Journal Vol.43 No.1

Background: The prevalence of diabetes mellitus (DM) continues to increase, and the disease burden is the highest of any medical condition in Korea. However, large-scale clinical studies have not yet conducted to establish the basis for diabetes prevention in Korea. Methods: The hospital-based Korean Diabetes Prevention Study (H-KDPS) is a prospective, multi-center, randomized, open-label controlled study conducted at university hospitals for the purpose of gathering data to help in efforts to prevent type 2 DM. Ten university hospitals are participating, and 744 subjects will be recruited. The subjects are randomly assigned to the standard care group, lifestyle modification group, or metformin group, and their clinical course will be observed for 36 months. Results: All intervention methodologies were developed, validated, and approved by Korean Diabetes Association (KDA) multidisciplinary team members. The standard control group will engage in individual education based on the current KDA guidelines, and the lifestyle modification group will participate in a professionally guided healthcare intervention aiming for ≥5% weight loss. The metformin group will begin dosing at 250 mg/day, increasing to a maximum of 1,000 mg/day. The primary endpoint of this study is the cumulative incidence of DM during the 3 years after randomization. Conclusion: The H-KDPS study is the first large-scale clinical study to establish evidence-based interventions for the prevention of type 2 DM in Koreans. The evidence gathered by this study will be useful for enhancing the health of Koreans and improving the stability of the Korean healthcare system (Trial registration: CRIS KCT0002260, NCT02981121).

차량 충돌 및 방호울타리 구조의 불확실성을 고려한 탑승자 보호성능 상호영향 해석

이상열 한국복합신소재구조학회 2019 복합신소재구조학회논문집 Vol.10 No.1

A car crash analysis was performed to predict passenger protection performances of a guard rail structure considering uncertainties of car crash and guard rail structures. Probabilistic parameters based on the Lain Hypercube Sampling method were generated to consider real car crash situations. Parametric examples represented a significance of the interactions between passenger protection performances and the probabilistic parameters. The results of this study may serve as a benchmark for future guidelines in designing guard rail structures for the passenger safety against the car crash. 본 연구는 차량 충돌 및 방호울타리 구조의 불확실성을 고려하여 탑승자의 보호성능과의 상호관계 분석을 수행하였다. 라틴 하이퍼큐브 샘플링 기법을 기반으로 실제 충돌 상황을 고려할 수 있는 확률적 변수를 결정하였다. 매개변수 예제는 탑승자 보호 성능과 확률적 매개변수와의 상관관계의 중요성을 나타내었다. 본 연구 결과는 차량충돌로 인한 탑승자 보호를 고려한 방호울타리의 설계에 대한 가이드라인을 제공할 수 있을 것으로 기대된다.

다양한 기하학적 형상을 갖는 흥간 분리된 복합신소재 적홍구조의 동적 불안정성

이상열,장석윤 한국복합신소재구조학회 2010 복합신소재구조학회논문집 Vol.1 No.1

본 연구 에서 는 면내 주기 하중을 받는 층간분리된 복합신소재 구조물의 동적 불안정 해석을 Sanders의 고차항 이론 에 근간하여 수행하였 다. 절점당 7개의 자유도를 사용한 2차원 유한요소 정식화에서 층간분리영역 경계에서의 변위 를 일치시키기 위한 변환기법을 적용하였다. 불안정 영역의 경계는 Bolotin의 이론을 적용하여 산정하였다. 경사판 및 웰에 대한 해석 결과는 기존 문헌 결과와 잘 일치하였 다. 경사판 및 웰 에 대한 새로운 해석 결과들은 곡률을 비롯한 다양한 기하학적 영향(경사각도,층간분리 크기,섬유보강 각도, 그리고 두께 방향으로의 층간분리 위치변화 등)과의 상호거동 관계를 보여 준다. 불안정 영역의 주기 하중의 크기에 대한 영향도 분석하였다. The dynamic instability analysis of delaminated composite structures su이ected to in-plane p비sating forces is carried out based on the higher order shell theory of Sanders. In the finite element (FE) formulation, the seven degrees of freedom per each node are used with transformations in order to fit the displacement continuity conditions at the delamination region. The boundaries of the instability regions are determined using the method proposed by Bolotin. The numerical results obtained for skew plates and shells are in good agreement with those reported by other investigators. The new results for delaminated skew plate and shell structures in this study mainly show the effect of the interactions between the radius-Iength ratio and other various parameters, for example, skew angles, delamination size, the fiber angle of layer and location of delamination in the layer direction. The effect of the magnitude of the periodic in-plane load on the instability regions is also investigated.

포스터 : 연제 9 ; 기능성 소화불량증의 질병의거

이상열,최석채,조유경,최명규,나용호 대한소화관운동학회 2003 대한소화관운동학회 춘계학술대회 Vol.15 No.-

Prevalence of Chronic Complications in Korean Patients with Type 2 Diabetes Mellitus Based on the Korean National Diabetes Program

이상열,전숙,권미광,박이병,안규정,김인주,김성훈,이형우,고경수,김두만,백세현,이관우,남문석,박용수,우정택,김영설 대한당뇨병학회 2011 Diabetes and Metabolism Journal Vol.35 No.5

Background: The Korean National Diabetes Program (KNDP) cohort study is performing an ongoing large-scale prospective multicenter investigation to discover the pathogenesis of type 2 diabetes in Korean patients. This study was performed to examine the prevalence of chronic complications in patients with type 2 diabetes among those registered in the KNDP cohort within the past 4 years. Methods: This study was performed between June 2006 and September 2009 at 13 university hospitals and included 4,265 KNDP cohort participants. Among the participants, the crude prevalence of microvascular and macrovascular diseases of those checked for diabetes-related complications was determined, and the adjusted standard prevalence and standardization of the general population prevalence ratio (SPR) was estimated based on the 2005 Korean National Health and Nutrition Examination Survey (KNHANES) population demographics. Results: Among the KNDP registrants, 43.2% had hypertension, 34.8% had dyslipidemia, 10.8% had macrovascular disease, and 16.7% had microvascular disease. The SPR of the KNDP registrants was significantly higher than that of the KNHANES subjects after adjusting for demographics in the KNHANES 2005 population. However, with the exception of cardiovascular disease in females, the standardized prevalence for the most complicated items in the survey was significantly higher than that in the KNHANES subjects. Conclusion: The prevalence of macrovascular disease and peripheral vascular disease were significantly higher in Korean patients with type 2 diabetes than in the normal population. However, no significant difference was noted in the prevalence of cardiovascular disease in females.

세션1-3 최신 기술에 의한 만성질환관리의 새로운 패러다임 : 당뇨병 자가관리를 위한 한국형 스마트폰 어플리케이션의 모색

이상열 한국보건행정학회 2014 한국보건행정학회 학술대회 논문집 Vol.2014 No.2

Use of bivariate gamma function to reconstruct dynamic behavior of laminated composite plates containing embedded delamination under impact loads

이상열,전종수 국제구조공학회 2019 Structural Engineering and Mechanics, An Int'l Jou Vol.70 No.1

This study deals with a method based on the modified bivariate gamma function for reconstructions of dynamic behavior of delaminated composite plates subjected to impact loads. The proposed bivariate gamma function is associated with micro-genetic algorithms, which is capable of solving inverse problems to determine the stiffness reduction associated with delamination. From computing the unknown parameters, it is possible for the entire dynamic response data to develop a prediction model of the dynamic response through a regression analysis based on the measurement data. The validity of the proposed method was verified by comparing with results employing a higher-order finite element model. Parametric results revealed that the proposed method can reconstruct dynamic responses and the stiffness reduction of delaminated composite plates can be investigated for different measurements and loading locations.

A numerical study on the soot and combustion performance of a diesel engine with pip shape

이상열,김민재,김하진 대한기계학회 2018 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.32 No.12

The shape of the combustion chamber plays an important role in the formation of the air-fuel mixture in the chamber, which has a great influence on the combustion efficiency and emission formation. The pip is a protruding shape at the center of the combustion chamber, and its importance has been evaluated to be relatively low. There has also been little research on off-highway diesel engines in comparison with on-highway diesel engines. When a high-pressure injection system is used in an off-highway diesel engine, which injects more fuel than on-highway engines, the shape of the pip greatly affects the mixture spray momentum and air flow in the combustion chamber. In this study, the pip geometry of a 2.4-liter off-highway engine was modified using three shapes: a step cone, W shape, and egg shape. We used 3-D combustion simulations to analyze the effects of the pip geometry on the mixture formation and combustion efficiency. We also analyzed the influence of the height and corner angle of the pip on the combustion and emission based on the egg shape, which was the most efficient. The results of this study could be used as a guide in designing combustion chambers for diesel engines.

다양한 기하학적 형상을 갖는 층간 분리된 복합신소재 적층구조의 동적 불안정성

이상열,장석윤,Lee, Sang-Youl,Chang, Suk-Yoon 한국복합신소재구조학회 2010 복합신소재구조학회논문집 Vol.1 No.1

The dynamic instability analysis of delaminated composite structures subjected to in-plane pulsating forces is carried out based on the higher order shell theory of Sanders. In the finite element (FE) formulation, the seven degrees of freedom per each node are used with transformations in order to fit the displacement continuity conditions at the delamination region. The boundaries of the instability regions are determined using the method proposed by Bolotin. The numerical results obtained for skew plates and shells are in good agreement with those reported by other investigators. The new results for delaminated skew plate and shell structures in this study mainly show the effect of the interactions between the radius-length ratio and other various parameters, for example, skew angles, delamination size, the fiber angle of layer and location of delamination in the layer direction. The effect of the magnitude of the periodic in-plane load on the instability regions is also investigated.