Evaluation of Embolization Effect of Hepatocellular Carcinoma by Hepatic Arterial Flow Study with $^{99m}Tc$-MAA SPECT

이병희,유형식,이종두,정진일,박창윤,이종태,Lee, Byung-Hee,Yoo, Hyung-Sik,Lee, Jong-Doo,Chung, Jin-Ill,Park, Chang-Yun,Lee, Jong-Tae The Korea Society of Nuclear Medicine 1994 핵의학 분자영상 Vol.28 No.1

This study was aimed to compare the density of the functional microcirculation of hepatocellular carcinoma (HCC) with normal liver and to investigate the effect of hepatic-arterial oily chemoembolization (HAE) by radionuclide examination. Methods : Eight patients with HCC proven by biopsy in five, and clinically and radiologically in three were included. The mixture of 2 cc normal saline with three to four mCi of $^{99m}Tc$-MAA was infused through a hepatic-arterial catheter for a minute. Dynamic images were obtained at a rate of 4 sec per frame for a minute, and static images and SPECT were followed. Results : In three patients who underwent hepatic arterial angiography (HAA) alone, radioactivity was markedly increased in tumors compared to the adjacent liver immediately after infusion of $^{99m}Tc$-MAA. The ratios of tumoral and extratumoral up-take (T/E ratio) were above 6.5 (range; $6.5{\sim}l9$, mean; 12.5). In four of the five patients who under-went superselective HAE, T/E ratio were remark-ably decreased ($0.5{\sim}1.3$). The areas of embolization were better delineated in radionuclide study than in postembolization HAA. In the other one who was considered to be embolized completely on HAA, strong radiouptake in the tumor was disclosed (T/E ratio; 7.0). Conclusions : Therefore hepatic-arterial flow study with radionuclide imaging using $^{99m}Tc$-MAA can be a valuable method to assess the accurate embolization effect in HCC. 본 저자들은 $^{99m}Tc$-MAA를 이용하여 정상 간조직에 대한 간암의 상대적인 미세 혈류량을 조사하고 간암 환자에서 간동맥 색전술을 시행 후 상대적인 혈류량의 변화를 검사함으로써 간동맥 색전술의 효과를 알아보고자 하였다. 여덟명의 간암 환자들을 대상으로 하였는데, 이 중 다섯 명은 조직 생검으로, 그리고 나머지 세 명은 임상적, 그리고 방사선학적으로 진단되었다. 3내지 4mCi의 $^{99m}Tc$-MAA를 2cc의 생리식염수에 혼합하여 간동맥내에 위치된 카테터(catheter)를 통하여 1분간에 걸쳐 서서히 주입한 후 바로 동적영상을 4초 간격으로 1분 동안 얻었으며, 이어서 정적 영상과 SPECT를 시행하였다. 간동맥 혈관 조영술만을 시행한 세명의 환자에서 $^{99m}Tc$-MAA를 주입하자마자 주변 간 조직에서 비해 간암내에 강한 방사능 섭취를 보였으며, 주변 간조직에 대한 간암의 방사능 섭취율은 6.5 이상이었고, 그 범위는 6.5에서 19였으며 평균은 12.5였다. 간동맥 색전술을 시행한 5명 중 4명에서 주변 간조직에 대한 간암의 방사능 섭취율이 심하게 감소하였다($0.5{\sim}1.3$). 또한 색전된 부위는 색전술 후 시행한 추적 간동맥 혈관 촬영상에서 보다 동위원소 검사에서 잘 관찰되었다. 간동맥혈관 촬영상에서 완전히 색전된 것으로 생각된 한 환자에서 동위원소 검사상 간암에 강한 방사능 섭취를 보였다(주변 간조직에 대한 간암의 방사능 섭취율 7.0). 따라서 본 저자들은 $^{99m}Tc$-MAA를 이용한 간 동맥 혈류 검사는 간암에서 색전술의 효과를 정확히 평가할 수 있는 유용한 검사법으로 이용될 수 있으리라 생각한다.

간암에서 색전술의 효과를 평가하는데 있어서 99mTc-MAA SPECT 를 이용한 간동맥 혈류 검사의 의의

이병희,유형식,이종두,정진일,박창윤,이종태 ( Byung Hee Lee,Hyung Sik Yoo,Jong Doo Lee,Jin Ill Chung,Chang Yun Park,Jong Tae Lee ) 대한핵의학회 1994 핵의학 분자영상 Vol.28 No.1

전세포 β- galactosidase 의 캡슐 고정화

이병희,정긍식,하태욱,박중곤 ( Byung Hee Lee,Geung Sik Jeong,Tae Wook Ha,Joong Kon Park ) 한국화학공학회 1995 화학공학의이론과응용 Vol.1 No.1

한약으로 관해가 유도된 극심한 설사의 궤양성대장염 환자 증례보고

이병희,원지윤,이향숙,Lee, Byung-Hee,Won, Jiyoon,Lee, Hyangsook 대한한의학방제학회 2021 大韓韓醫學方劑學會誌 Vol.29 No.3

Ulcerative colitis (UC) is one of inflammatory bowel diseases (IBD) with unknown etiopathogenesis. This case report details remission of UC induced by Korean herbal medicine treatment. A 31-year-old male patient diagnosed as UC after a series of examinations including endoscopy and fecal calprotectin (FC) test. He had severe bloody diarrhea over 10-20 times a day despite taking 5-aminosalicylic acid and steroid. He was given individualized Korean herbal medicine Dowha-tang according to pattern identification. After taking Dowha-tang for 7 months, clinical remission was achieved. The symptoms disappeared and FC level went down to normal level. No adverse events were reported. This case report shows that Korean herbal medicine treatment may have the potential for clinical remission of UC. Further investigation is warranted.

高麗時期 寺院에서의 敎學活動

李炳熙(Lee, Byung-hee) 한국사연구회 2011 한국사연구 Vol.155 No.-

This study focused on Buddhist monks’ learning and training, specialization in education and study, and the guidance for Zen Buddhist meditation they received to understand academic activities developed in Buddhist temples during Goryeo. The study did not cover Buddhist monks’ study of Buddhism and writing of their academic activities. Right after entering the Buddhist priesthood, Buddhist monks would gain elementary knowledge of the scriptures and then wander around many places like clouds or rivers. In the process, they would gain further learning from high priests and made further commitment to study with their peers. It was an often case that they formed a society and did training in groups, Buddhist monks usually developed a thorough understanding of their sects’ teachings and explanations and, at the same time, had some considerable understanding of other sects’ doctrines and even profound knowledge of Confucianism. Many Buddhist monks gathered in Buddhist temples where high priests resided, The study of master Buddhist priests was transmitted to younger students through a process of teaching and instructing. There would be as many as 1,000 pupils in a Buddhist temple. Thanks to their learning, the study of master Buddhist priests was able to spread around the nation. Some would even leave a deep impression through the last teaching at Hasanso. The Buddhist teachings and explanations went spreading through all sorts of events held in Buddhist temples. It was common that high Buddhist priests gave a lecture on Buddhist doctrines to a gathering of many Buddhist monks and secular people to attend a Nakseong event. The monks of Zen Buddhism made considerable achievements by training in a group at a Chongrim or Damseon rally for months. Splendid large-scale events held in Buddhist temples in and out of Gaeseong made an important contribution to the spread of Buddhist teachings and explanations. In addition. Buddhist priest qualification exams involving group discussions and questions & answers also contributed to the spread of Buddhist teachings and explanations. Entering the late period of Goryeo, there was a shift among Buddhist monks from studying or training in groups to individual isolated training. which made them pay less attention to study through books. Another new trend was the rarity of Buddhist monks that studied many different disciplines of study. Disturbances among high-rank Buddhist priests and in the Buddhist priest qualification exam system caused poor academic activities in Buddhist temples. Those activities performed in Buddhist temples helped Buddhist teachings and explanations be transmitted far and wide and have big influences on the secular world. It was through such a process that social discourse based on Buddhist teachings and explanations was able to form and spread.

사무소 건물의 지하주차장 출입구를 통한 건물의 공기유동 특성에 관한 연구

이병희(Lee, Byung-Hee),이수환(Yee, Su-Whan),김효진(Kim, Hyo-Jin),강동화(Kang, Dong-Hwa),여명석(Yeo, Myoung-Souk),김광우(Kim, Kwang-Woo) 대한건축학회 2015 대한건축학회논문집 Vol.31 No.8

This paper shows the characteristics of airflow by infiltration through opening of underground parking lot in office building. This infiltration affects indoor air quality and building energy consumption. The effect of the wind velocity, direction and temperature differences between indoor and outdoor on the airflow through the building envelop has been investigated. In this study, the effect of the infiltration through opening of underground parking lot in office building will be analyzed using airflow network modeling by CONTAMW 3.0. Office building were simulated to confirm these characteristics. It is important to estimate the airflow and pressure difference across opening of underground parking lot for understanding the energy impacts of infiltration in office building because infiltration is likely to affect building energy consumption. As a result, there is general upward movement of air inside the building under outside cold conditions with airflow into vertical shafts from the lower floors and out to the upper ones. For preventing problems from the stack effect in office building, the first concern should be the improvement of airtightness in the opening of underground parking lot.

전세포 Escherichia coli β-galactosidase의 캡슐고정화

이병희(Byung Hee Lee),박중곤(Joong Kon Park) 한국생물공학회 1996 KSBB Journal Vol.11 No.4

자연환기에 따른 공동주택 실내 라돈농도 변화

이병희(Lee, Byung-Hee),김선동(Kim, Sun-Dong),전주영(Chun, Chu-Young) 대한건축학회 2019 대한건축학회 학술발표대회 논문집 Vol.39 No.2

산업노동연구 : 노동시장과 인적자원개발 ; 사내하도급의 활용 원인과 고용 성과

이병희 ( Byung Hee Lee ) 한국산업노동학회 2012 산업노동연구 Vol.18 No.1

「사업체패널조사」(한국노동연구원)를 이용하여 사회적으로 논란이 큰 사내하도급을 활용하는 원인과 고용성과를 분석하였다. 우선 사내하도급을 활용하는 주된 이유는 노동비용 절감인 것으로 나타났다. 시장의 불확실성 또는 노조 압력 등으로 인한 비시장적인 제약에 대응하여 고용 유연성을 확보하기 위해서나 전문적인 숙련의 확보 필요성 때문에 사내하도급을 활용하는 것이라고 보기는 어렵다. 둘째, 사내하도급을 활용하는 사업체에서 정규직 비중은 하락하여, 사내하도급과 정규직은 대체관계가 존재하며 일자리의 질이 하락할 수 있음을 시사한다. 셋째, 사내하도급 활용에 따라 일자리 순증가율이 낮아서, 기업 수익성에는 기여할 수 있지만 노동수요 촉진으로 이어지지는 않는다. 이상의 분석결과는 도급계약이라는 시장 관계를 통해 노동법적인 사용자의 책임을 지지 않는 사내하도급 활용관행에 대한 규율의 필요성을 보여준다. Using data from 2007-09 Workplace Panel Survey conducted by Korea Labor Institute, this paper investigates what determines the use of in-house subcontracting and how such arrangement affects the employment performance. Firstly, I hypothesize thar four factors affect the use of in-house subcontracting: labor cost, employment adjustment, skill requirement and unionization. I find evidence that reducing labor cost is the main determinant of the use of in-house subcontracting. Secondly, increasing in-house subcontract led to decreasing the proportion of regular workers among all employees. This implies that in-house subcontracting tends to substitute, rather than complement, standard employment. Thirdly, The rates of job creation and net employment growth in firms which use in-house subcontracts are lower than those which do not. These findings suggest the need for regulation on in-house subcontracting.

朝鮮前期 圓覺寺의 造營과 運營

李炳熙(Lee Byung Hee) 한국문화사학회 2010 文化史學 Vol.0 No.34