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유산소운동과 diacylglycerol 섭취가 비만인의 혈중 지질성분 및 안정 시 대사량의 변화에 미치는 영향
이문열(Moon-Youl Lee),백일영(Yl-Young Paik),곽이섭(Yi-Sub Kwak) 한국생명과학회 2010 생명과학회지 Vol.20 No.8
본 연구는 체지방을 감소시키는데 효과적이라는 diacylglycerol (DG) 섭취와 유산소운동이 체구성비의 변화 및 혈중 지질 개선에 미치는 영향을 규명하고 안정 시 대사량 변화를 관찰함으로써 임상적 및 대사적 측면에서 비만 개선 효과를 규명하는데 그 목적이 있었다. 본 연구의 대상은 의학적으로 다른 질병을 동반하지 않은 비만 남자 대학생으로서 연구의 의의를 충분히 이해하고 자발적으로 참여 의사를 밝힌 사람으로 선정하였으며, 체지방 측정 후 25%미만인 자와 흡연자는 대상에서 제외하였다. 모든 피험자들은 기본검사와 사전검사가 끝난 후 세가지(D, E, DE) 집단에 6명씩 무선 배정하였다. 첫 번째 실험군(D)은 diacylglycerol 섭취 조건으로 12주 동안 diacylglycerol을 섭취하였고, 두 번째 실험군(E)은 12주 동안 러닝 트레이닝을 실시하였다. 마지막 세번째 실험군(DE)은 12주 동안 diacylglycerol 섭취와 유산소 트레이닝을 실시하였으며, 본 연구결과 모든 그룹에서 12주 동안의 그룹별 처치가 진행됨에 따라 체지방이 감소하는 경향을 보였다. 안정 시 대사량은 D그룹을 제외하고 모든 그룹에서 증가하는 경향을 보였으며 운동과 다이아실글리세롤 섭취에 따라 콜레스테롤의 감소가 일어났다. 추후 카테콜라민, CAMP, HSL, Insulin 등과 같은 지방대사와 관련된 항목들에 대한 추가적인 분석이 이루어짐으로써, DG섭취와 트레이닝의 비만개선효과를 보다 신뢰성 높게 예측할 수 있으리라 본다. The aim of this study was to investigate the combined effects of aerobic training and diacylglycerol ingestion on lipid profiles and resting metabolic rate changes in obese men. The subjects were divided into 3 groups: the Diacylglycerol group (D, n=6), aerobic training group (E, n=6), and diacylglycerol ingestion and aerobic training group (DE, n=6). Diacylglycerol was ingested and aerobic exercise training performed for 12 weeks. The information received from the research was calculated through a Windows SPSS/PC+ Ver. 12.0K statistics package to standardize the means and deviations for each group. Then, two-way repeated measures ANOVA was used to evaluate the research hypothesis. Percent body fat, blood lipid profiles and resting metabolic rate changes were tested to evaluate the combined effect of aerobic exercise training and diacylglycerol ingestion. The results of this study were as follows; DG ingestion was shown to have a positive effect on body weight and body fat, while having a negative effect on resting metabolic rate changes. However, aerobic training was shown to have a positive effect on all factors including body weight, body fat, and resting metabolic rate. In conclusion, DG ingestion and exercise training were not shown to have synergistic effects on resting metabolic rate changes, percent body fat and lipid profiles, while aerobic exercise training was shown to have a positive effect on resting metabolic rate changes, percent body fat, and lipid profiles. To investigate the therapeutic effect of DG ingestion and aerobic exercise for obese men, analysis of catecholamine, cAMP, HSL, or insulin sensitivity should be considered.
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Diacylglycerol 섭취와 Weight Training이 비만 남자대학생의 체중, 체지방, RMR 및 혈중 지질성분에 미치는 영향
이문열 ( M. Y. Lee ),김도연 ( D. Y. Kim ),곽이섭 ( Y. S. Kwak ),이하영 ( H. Y. Lee ) 한국운동생리학회(구 한국운동과학회) 2011 운동과학 Vol.20 No.2
본 연구는 체지방을 감소시키는데 효과적인 DG (Diacylglycerol) 섭취와 웨이트 트레이닝이 남자대학생을 대상으로 체중, 체지방, RMR 및 혈중 지질성분에 미치는 영향을 구명하고자 3그룹 (diacylglycerol 투여: D그룹, 웨이트 트레이닝: W그룹, diacylglycerol 투여와 웨이트 트레이닝: DW그룹)으로 나누어 12주간 운동을 실시한 후 운동전과 후의 체중, 체지방, RMR 및 혈중 지질성분을 측정하여 비교 분석하였다. 본 연구의 결과 DG 투여그룹은 체중, 체지방률, RMR 및 혈중지질성분 모두 감소하는 경향을 보였다. 따라서, DG의 시너지 효과는 웨이트 트레이닝과 병행했을 때만 체중과 체지방, 혈중 지질 성분에 긍정적인 영향을 나타내었고 보다 안전하고 효과적인 비만개선의 효과를 알아보기 위해서 DG의 에너지 대사 기전에 대한 연구가 선행되어야 한다. 카테콜라민, cAMP, HSL, Insulin등과 같은 지방대사와 관련된 항목들에 대한 추가적인 분석이 이루어짐으로써, DG섭취와 트레이닝의 비만개선효과를 보다 신뢰성 높게 예측할 수 있으리라고 본다. The purpose of this study was to investigate the effects of diacylglycerol supplementation and weight training exercise on body fat, RMR, and blood lipid changes in college male students. The subjects were divided into 3 groups: diacylglycerol supplementation group (D, n=6), weight training group (W, n=6), and diacylglycerol supplementation and weight training group (DW, n=6). Exercise training and diacylglycerol supplementation were performed for 12 weeks, and blood sample were taken 4 times, which were at rest and the end of exercise of before and after training. Lipid profiles in blood was measured to find out the effect of antioxidant system. Body weight, %body fat, and RMR were also measured to find out antiobesity effects through the combined effect of dietary diacylglycerol and weight training. The result of this study were as follows; DG supplementation showed a positive effect on body weight and body fat, whereas negative effect on RMR and blood lipid. Weight training showed a positive effect on all of factors including body weight, body fat, RMR and blood lipid. In conclusion, DG supplementation did not reveal synergistic effect on the antioxidant system. While DG supplementation and weight training revealed synergistic effect on weight, %body fat, and lipid profile in blood. To investigate the therapeutic effect for obese college student, role of DG for energy metabolism and analysis about factors for lipid metabolism such as catecholamine, cAMP, HSL, or insulin should be preceded.
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유도선수들의 반복운동이 혈중 코티졸과 지질과산화 및 creatine kinase 활성에 미치는 영향
백일영,곽이섭,이문열 한국생명과학회 2004 생명과학회지 Vol.14 No.4
The purpose of the present study is to investigate the lipid peroxidation, creatine kinase activity and cortisol hormone levels following the training intensity in elite judo players. Six elite Judo players participated in the experiments (3h repetition judo program), which include stretching, judo skill practice and cool down without recess. Blood sampling were taken at the judo gymnasium at the time of resting, 1h training, 2h training, 3h training, 2h recovery, and 24h recovery time and this were analyzed for CK, MDA and Cortisol levels. The results obtained were analyzed via repeated measures of ANOVA using SPSS package program (ver.10.0) and a value of p<.05 was considered statistically significant. The results from this study were as follows. In the CK levels, which reflect the contribution of creatine phosphate and muscle damage degree, there was a significant difference (p<.05) after judo training in every period. Recovery 24h showed the highest level. In the MDA levels, which reflect lipid peroxidation, there was a significant difference (p<.05) after judo training. Recovery 2h showed the lowest level. In the cortisol hormone levels, which reflect stress status, there was a significant difference (p<.05). In this study, we can conclude that For the trained athletes, MDA level was lower at the time of exercise compare to the other period, this is caused by the increased antioxidant defence mechanism.
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