방사선 조사가 백서 악하선 줄무늬관세포에 미치는 영향에 관한 투과전자현미경적 연구

이규찬,이상래,Lee Gyu-Chan,Lee Sang-Rae 대한영상치의학회 1990 Imaging Science in Dentistry Vol.20 No.2

The purpose of this study was to investigate the effects of irradiation on the striated duct cells of the rat submandibular gland ductal tissues which control the characteristics of saliva. For this study, the experimental group was composed of 36 irradiated Sprague Dawley strain rats divided into 8 subgroups 1 hour, 2 hours, 3 hours, 6 hours, 12 hours, 24 hours, 48 hours, 72 hours after irradiation. 4 non-irradiated rats were used as the control group. The experimental animals were singly irradiated with a dose of 18Gy gamma ray to their head and neck region by the Co-6- teletherapy unit and sacrificed after each experimental duration. The specimens were examined with a light microscope with an H-E stain and with a trans- mission electron microscope. The results of this study were as follows. In the light micrograph, a severe atrophic change occurred in the striated duct cells at 2hours after irradiation and gradual recovery occurred from 6 hours after irradiation. 2. The nuclear chromosomes of the striated duct cells were changed granular at 2 hours after irradiation. Recovery was observed at 6 hours after irradiation. Nuclear bodies were also observed from 3 hours after irradiation. 3. The mitochondria of the striated duct cells had indistinct cristae at 2 hours after irradiation, and were degenerated or swollen at 3 hours after irradiation. They recovered, however, from 6 hours, with an increasing number at 48 hours and a regular arrangement was observed at 72 hours after irradiation. 4. The microvilli showed atrophic changes at 2 hours after irradiation and were almost lost at 3 hours after irradiation. They were observed again from 48 hours after irradiation. 5. The rough endoplasmic reticulum and golgi body were not apparent at 1 hour after irradiation and were dilated with degeneration 2 hours after, but intact rough endoplasmic reticulum were observed from 3 hours after irradiation and developed well at 24 hours after irradiation. By the result of this study, showing a mild change in the functional morphology of the salivary striated duct cells immediately following irradiation, it is considered that the many complications which occur after radiation therapy, will disappear in time with the histological and the functional recovery of the glandular tissues.

누낭에 발생한 편평상피세포암 1예

이규찬 ( Lee Gyu Chan ) , 권상원 ( Kwon Sang Won ) , 백세현 ( Baeg Se Hyeon ) 대한안과학회 2003 대한안과학회지 Vol.44 No.8

한-일 교차언어검색에서의 질의 문맥 정보를 이용한 대역어 변환 확률 모델

이규찬(Gyu-Chan Lee),강인수(In-Su Kang),나승훈(Seung-Hoon Na),이종혁(Jong-Hyeok Lee) 한국정보과학회 언어공학연구회 2005 한국정보과학회 언어공학연구회 학술발표 논문집 Vol.2005 No.10

교차언어 검색 과정에서는 질의나 문서의 언어를 일치시키기 위한 변환 과정이 필수적이며, 이런 변환 과정에서 어휘의 중의성으로 인해 하나의 어휘에 대응하는 다수의 대역어가 생성됨으로써 사용자의 정보 욕구를 왜곡시켜 검색의 성능을 저하시킬 수 있다. 본 논문에서는 어휘 중의성 문제를 해결하기 위해서 질의의 문맥 정보를 이용하여 변환 질의의 확률을 구함으로써 중의성을 해소하는 방식을 제시하고, 질의의 길이, 중의도, 중의성을 가진 어휘의 비율 등에 따라서 성능이 어떻게 변하는지 비교함으로써 이 방법의 장점과 단점을 분석한다. 또한 현재의 단점을 보완하기 위한 차후 연구 방향을 제시한다.

바이그램 색인에 기반한 한 - 일 교차언어검색

이규찬(Gyu-Chan Lee),강인수(In-Su Kang),나승훈(Seung-Hoon Na),이종혁(Jong-Hyeok Lee) 한국정보과학회 2005 한국정보과학회 학술발표논문집 Vol.32 No.1

교차언어검색 시스템은 다양한 언어자원을 필요로 한다. 여기서는 한-일 대역어 사전과 일본어 문서의 바이그램 색인만을 이용해서 교차언어검색을 수행하는 방법을 제시한다. 한국어로 된 자연어 질의에서 형태소 분석기 등의 도움 없이 간단하게 일본어 대역어 리스트를 생성할 수 있는 방법과, 검색의 성능을 올릴 수 있도록 대역어에 가중치를 부여하는 방법을 제안한다. 그리고 실험을 통해 제시한 방법을 평가하고 분석한다.

이중 PI- Lead 제어기를 이용한 EOTS 제어에 대한 연구

이규찬(Gyu Chan Lee),강찬휘(Chan Hwi Kang),곽동기(Dong Gi Kwag) 항공우주시스템공학회 2023 항공우주시스템공학회 학술대회 발표집 Vol.2023 No.10

병원종사자의 VDT증후군 자각증상과 건강영향에 관한 연구

이승환,정병곤,이규찬,이광철,배성복,Lee, SeungHwan,Jeong, Byeong Gon,Lee, Gyu Chan,Lee, Gwang Cheol,Bae, Seong Bock 대한핵의학기술학회 2012 핵의학 기술 Vol.16 No.2

Purpose : This study aims to examine hospital employees' subjective symptoms of VDT syndrome (Video display terminal syndrome) and figure out their effects on health conditions and correlations. Materials and Methods : This study used a structured self-administering questionnaire and gained data from 125 subjects. The questionnaire consists of total 62 questions, and they went through real number, percentage, ${\chi}^2$-terst, t-test, one-way ANOVA, and logistic regression analysis. Results : Regarding the difference in the types of subjective symptoms of VDT syndrome by jobs, there was statistically significant difference in ophthalmic symptoms, systemic symptoms, and musculoskeletal symptoms. About the correlation between the subjective symptom points of VDT syndrome by the types of symptoms, there was statistically significant correlation all in skin trouble, backache, upper limb muscle pain, lower limb muscle pain, fatigue in the head and eyes, and depression or anxiety disorders. There was significant correlation between the subjective symptom points of VDT syndrome and subjective health conditions. Conclusion : Hospital employees' subjective health conditions had significant correlation with subjective symptom points of VDT syndrome. This result shows that as radiologists' and also other hospital employees' working conditions change into VDT environment, VDT syndrome gradually appears more and more. This implies that it is needed to designate not only radiologists but also all the other hospital employees as jobs exposed to the working environment of VDT syndrome and provide preventive measures, education, and publicity for it afterwards.

PET/CT 검사에서 Stomach의 추가 촬영을 줄이기 위한 수분 섭취의 유용성

이승환,배성복,정병곤,이규찬,이광철,배원규,Lee, Seung-Hwan,Bae, Seong-Bok,Jeong, Byeong-Gon,Lee, Gyu-Chan,Lee, Gwang-Cheol,Bae, Won-Gyu 대한핵의학기술학회 2011 핵의학 기술 Vol.15 No.1

암 환자의 영상에서 stomach의 병변과 분비물을 구분하기란 쉽지 않다. 이 연구의 목적은 검사 전 충분한 수분 섭취로 stomach의 병변과 분비물의 분별력을 높임으로서 추가 촬영을 줄이기 위하여 시행하였고 본 연구는 총 228명의 암 환자로 2010년 8월 18일부터 2010년 9월10일까지 진행하였으며, 2010년 8월 18일부터 2010년 8월 31일까지는 수분섭취 제한환자가 115명이었고, 2010년 9월 1일부터 2010년 9월 10일까지는 촬영 직전 수분을 500 cc 정도 섭취한 후 검사를 진행한 환자로 113명이었다. 이 검사를 시행한 결과 전체 암 환자 228명을 대상으로 촬영 수분 섭취 제한 환자는 총 115명이고, 이중 추가 촬영이 없는 환자가 89명이었고, stomach 추가 촬영을 진행한 환자가 13이었으며, 기타 추가 촬영을 진행한 환자는 13명이었다. 그리고 촬영 직전 수분을 500 cc 정도 섭취한 후 검사를 진행한 환자 113명 중 추가 촬영이 없는 환자가 109이었고, stomach 추가 촬영을 진행한 환자가 1명이었으며, 기타 추가 촬영을 진행한 환자는 3명에 해당하였다. 이와 같은 결과로도 수분을 500 cc 정도 섭취하고 검사를 진행한 환자에게서 추가 촬영이 줄었음을 알 수 있었으나, 정확한 유의성을 알기 위하여 pearson의 chi-square test를 시행한 결과 유의확률이 0.05보다 작은 0.001이었으므로 두 집단은 유의한 관련성이 있음을 알 수 있고 최소 기대빈도가 6.94로서 5보다 작은 기대빈도가 없었으므로 pearson의 정확한 검정을 할 필요는 없었고, 위의 연구로 인하여 물을 검사 직전 약 500 cc 정도 섭취하고 촬영을 진행하면 stomach 추가 촬영을 현저히 줄일 수 있으며 기타 추가 촬영 또한 줄일 수 있음을 알 수 있었고 검사 지연 시간 또한 줄일 수 있을 것으로 사료된다. Purpose: With the introduction of PET since 1994, test methods have made rapid progress. Accordingly, the studies on the diagnosis and treatment of cancer as well as treatment response evaluation PET test are useful. However, it is difficult to divide stomach lesions and secretion. The purpose of this study is to reduce additional shooting by dividing lesions and secretion of stomach. Materials and Method: This study aiming at total 228 cancer patients was conducted from Aug 18 to Sep. 10, 2010. Among them, 115 patients had a test without water intake before shooting from Aug. 8 to 31 and 113 had a test after drinking 500 cc water right before shooting from Sep. 1 to 10 The Discovery ST PET/CT (GE Healthcare, USA) was used, and pearson's chi-square test was conducted to analyze significance through SPSS (Ver.18). Results: Among the total 228 cancer patients, there were 115 who had a test without water intake before shooting, 89 who had no double additional shooting, 13 who had stomach additional shooting and 13 who had other additional shooting. In addition, 109 had no additional shooting among 113 who had a test after taking 500 cc water, 1 had stomach additional shooting and 3 had other additional shooting. According to the findings above, the patients who had a test without water intake show reduced additional shooting, but for more exact significance, pearson's Chi-square test was carried out and the significance percentage was 0.001 that is smaller than 0.05, which means two groups have a significant relationship. As the minimum expectation frequency was 6.94 and there was no expectation frequency smaller than 5, so that it doesn't need to carry out pearson's exact verification. Conclusion: The above analysis has found that if one drinks 500cc water before the test, not only stomach additional shooting but also other additional shooting can be dramatically reduced, and test delay can be also reduced.