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한국인의 기능성 소화불량증 환자에서의 증상관찰, 아형분류 및 이에 대한 시사프리드의 효과
최명규 ( Myung Gyu Choi ),최규완 ( Kyu Wan Choi ),김나영 ( Na Young Kim ),임선희 ( Seon Hee Lim ),이계희 ( Kye Heui Lee ),김성국 ( Sung Kook Kim ),최용환 ( Yong Hwan Choi ),송치욱 ( Chi Wook song ),김혜랑 ( Heu Rang Kim ),임창영 ( 대한소화기기능성질환·운동학회 1998 Journal of Neurogastroenterology and Motility (JNM Vol.4 No.1
Background/Aims : The aims of this study were to determine subgoups of functional dyspesia and to evaluate the short-term effect of cisapride in patients with functional dyspepsia in Korea. Methods . 1025 patients, with a mean age of 42.6 years, with symptoms of functional dyspepsia, were recruited consecutively and upper gastrointestinal symptoms were investigated by interview in 41 hospitals in Korea. In an open, multicenter trial, 1025 patients received Smg of cisapride three times a day (TID) for at least .2 weeks for the treatment of symptoms of functional dyspepsia. When necessary, the dose of cisapride was increased to 10mg TID and the duration of therapy was extended to 4 weeks. Results . The most frequently reported symptoms of functional dyspepsia were epigastric discomfort or fullness (85%), bloating (70%), belching (53%), early satiety (52%) and epigastric pain (46%) retrospectively. Subgroups of functional dyspepsia were as follows; dysmotility-like 73.5%, ulcer-like 39.7%, reflux-like 13.0%, and unspecified dyspepsia 14.0%. However, 33.2% of subjects with functional dyspepsia could be classified into more than one subgroup. Upper gastrointestinal symptoms were decreased to average 50.3% (range; 42.2 to 59.2%) after 2 weeks of cisapride treatment and to 25% (19.2 to 29.9%) after 4 weeks. cisapride therapy resulted in good or excellent improvement in 59.0% of the patients after two weeks, in 75% of patients after 4 weeks. Adverse events were occurred in 52 patients (5.8% of all patients), most commonly, loose stools or diarrhea (3.5%), abdominal pain (1.1%), and dizziness (0.3%). The majority of adverse events was mild and transient in nature and led to premature discontinuation of treatment in 4 patients. Conclusions . Although the majorities of patients with functional dyspepsia have dysmotility like symptoms in Korea, there is such overlap among the dyspepsia subgroups. Most patients responded well to a short therapeutic trial with cisapride without significant side effects.
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박정진(Jeong Jin Park),임선희(Seon Hee Lim),김봉룡(Bong Ryong Kim),김형완(Hyoung Wan Kim),김준완(Joon Wan Kim),김태형(Tae Hyong Kim),장유현(Yoo hyun Jang),이계희(Kyu Heui Lee),양대현(Dae Hyun Yang) 대한소화기학회 2001 대한소화기학회지 Vol.38 No.1
Idiopathic portal hypertension (IPH) is a rare disease characterized by overt splenomegaly and portal hypertension in the absence of cirrhosis or vascular obstruction. The most common cause of death in IPH patients is known to be variceal bleeding, which is usually treated with surgical method. Recently, interventional radiologic methods such as transjugular intrahepatic portocaval shunt, ballon-occluded retrograde transvenous obliteration, or partial splenic embolization (PSE), have been tried to control portal hypertension. A 24-year-old man presented with repeated gastrointestinal bleeding due to rupture of esophageal varices, but his liver function tests were completely normal and any possible etiologies of his portal hypertension couldn’t be demonstrated. He was diagnosed as IPH by laparoscopic liver biopsy after PSE, which could control portal hypertension as well. For twelve months after PSE, he hasn’t experienced bleeding again. We report the case of PSE to control portal hypertension in a patient with IPH who presented with variceal bleeding. (Korean J Gastroenterol 2001;38:48-52)
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김태형,임선희,장유현,김형완,김준완,김봉룡,박정진,이계희,최신은 대한소화기내시경학회 2001 Clinical Endoscopy Vol.23 No.1
The prevalence of intestinal tuberculosis has been markedly decreased with the development of antituberculoug chemotherapy, improved economic conditions, preventive medicine and early detection and treatment of pulmonary tuberculosis. An even more impressive resurgence of pulmonary and extrapulmonary tuber culosis has been seen in recent years among persons infected with the human immunodeficiency virus. The most common signs of infeshna1 tuberculosis is the ileocecal region, and duodenum is a rare site. Symptoms and signs of duodenal tuberculosis are nonspecific. The gross pathologic appearance of the duodeznal tuberculous lesions has to its traditional categoriration into three farms. 1) ulcerative, 2) hypertrophic, and 3) ulcerohypertrophic (mixed). Hypertrophic lesions of the duodenal tuberculosis should be differentiated from duodenal adenocarcinoma and lymphoma. We herein report a case of duodenal tuberculosis presenting as intraluminal protruding mass in gastroduodenoscopy and multiple intraabdomina1 lymphadenopathy on abdominal CT. We have confirmed the duodena1 tuberculosis by endoscopic biopsy, and review the current literatures.
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임병철,김태형,임선희,장유현,김형완,김준완,김봉룡,박정진,이계희 대한소화기내시경학회 2001 Clinical Endoscopy Vol.23 No.1
Impaction of an ingesfed foreigm body in the colon is uncommon but surgical or endoscopic intervention is occasionally needed when serious complicafions such as perforation, obstruction or hemorrhage occur. Several factors may predispose a patient to ingestion and subsequent impaction of lower intestinal foreign body. It is more common in the elderly who wear dentures, in the mentally infirm, in chronic alcoholics or rapid eating. The majority of impaction occurs at narrowing and angulation such as ileocecal valve or rectosigmoid junction. The diagnosis of lower intestinal foreign body should be considered, among more common conditions, in the differential diagnosis of elderly patients who present with altered bowel habits. We report the case with a literature review that successfully endoscopically removed the fish bones impacted in the rectosigmoid colon complicated by rectal bleeding.
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