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      • 명상의 의학적 적용

        이강욱 동국대학교 종학연구소 2019 宗學硏究 Vol.2 No.-

        명상과 마인드풀니스는 이미 대표적인 의학 용어 사전인 MeSH 용어로 등재되어 있고, 현대 의료 체계 내에서 건강과 웰빙에 초점을 맞춘 접근법을 강조하면서 정신적, 정서적, 기능적, 영적, 사회적, 공동체적 요소를 통합적으로 고려하는 의료서비스의 한 분야로 공식적인인정을 받고 있다. 최근 미국 통계에 따르면 대표적인 보완대체의학서비스 중에서도 명상이 요가나 카이로프렉틱에 비해 이용률의 매우가파른 증가세를 보이고 있다. 또 코크란 라이브러리, 임상시험등록사이트, Pubmed 등 주요 의학 관련 데이터베이스 통계를 살펴보면 명상을 주제로 한 의학 연구 숫자도 최근 10년 간 폭발적인 증가세를 보이고 있다. 명상에 의한 신경생물학적 변화는 유전자, 뇌 구조 및 기능, 신경심리학 등의 영역별로 명확하게 밝혀지고 있다. 명상은 후생유전자의 변화를 통해 만성 스트레스로 인한 염증성 반응이나 질환의 위험성을 현저히 낮출 것으로 보이고, 텔로미어 길이 변화로 건강한 노화를 기대할 수 있게 한다. 뇌영상 기법을 이용한 명상 연구에서 전두극 피질, 감각 피질, 섬엽, 전방 및 중앙 대상회피질, 해마, 안와전두피질, 상세로다발, 뇌량 등이 주요 변화 부위로 밝혀지고 있다. 대규모 종단 연구인 ReSource Project와 수천 건의 기능적 자기공명영상 결과의메타분석 엔진인 Neurosynth에 의한 연구 결과도 주목할 만하다. 또한마인드풀니스 명상은 주의력, 감정 조절, 자기 자각 능력의 향상을 가져온다고 보고되고 있다. Meditation and mindfulness are already listed in the MeSH list, and are officially recognized as a field of medical services that collectively consider mental, emotional, functional, spiritual, social and community factors, emphasizing an approach focused on health and well-being of people within the modern medical system. According to recent U.S. statistics, meditation among the leading complementary alternative medicine services shows a very steep increase in utilization rates compared to yoga and chiropractic. Also, in the major medicine-related database such as the Cochrane Library, ClinicalTrials.gov Archive, and Pubmed, the number of studies under the theme of meditation has been on an explosive increase over the past decade. Neurobiological changes by meditation have been clearly identified in the fields of genes, brain structure and function, and neuropsychology. Meditation is expected to significantly reduce the risk of inflammatory reactions or inflammatory diseases due to chronic stress through changes in the epigenome, to enable healthy aging with changes in telomere length. Studies using brain imaging techniques have shown that the frontopolar cortex, sensory cortices, insula, anterior and middle cingulate cortex, hippocampus, orbitofrontal cortex, superior longitudinal fasciculus, corpus callosum. ReSource Project by Max Planck Institute and Neuroynth, a meta-analysis engine of thousands of functional magnetic resonance imaging results, are also noteworthy. It is also reported that mindfulness meditation results in improved attention, emotional control, and self-awareness.

      • KCI우수등재

        방사성 옥도 ( 131Ⅰ ) 가 Guinea Pig 의 난소 , 자궁 및 성주기에 미치는 영향

        이강욱,윤화중,이규승 ( K . W . Lee,H . J . Yoon,K . S . Lee ) 한국축산학회 1973 한국축산학회지 Vol.15 No.2

        The effects of radioiodine (^(131)I) administration on the histology of ovary and uterus and sexual cycle of the mature guinea pigs were observed. A single dose of 4.5 mC radioiodine per ㎏ body weight was injected subcutaneously. On the 1, 7, 14, 28, 42 and 56th day after radioiodine treatment, five treated and 5 control guinea pigs were sacrificed and their ovary and uterus were examined histologically. The variations in sexual cycle were examined by vaginal smear method through the experimental period. The results obtained were as follows: 1. No histological changes in the ovary were observed on the first day after treatment. On the 7th day after treatment, however, some atretic follicles were appeared and granulosa cells were changed with pyknosis and karyorrhexis. From the 14th day onwards, primordial follicles began to be damaged with a tendency to be severe gradually. After 42 days atretic follicles .and atrophy or hypoplasia of interstitial cells wore observed. On the 56th day after treatment, these ovaries began to be restored to the normal state. 2. The atrophy of myofibrils and multiplications of interstitial connective tissue of tunica muscularis were observed in the uterus from after treatment. 3. The change in sexual cycle of the treated guinea pig was apparent. The diestrus period extended in some guinea pigs on the 10th day after treatment. From the 21st day onwards, the distinct extension of diestrus period was observed.

      • 인슐린 비의존성 당뇨병에 의한 말기 신부전증 환자에서 iPTH치 및 골밀도에 관한 연구

        이강욱,김종학,황평주,송민호,김영건,노흥규,신영태 충남대학교 의과대학 지역사회의학연구소 1999 충남의대잡지 Vol.26 No.1

        The patients with diabetic ESRD have been reported to be suffered from more serious morbidity and mortality than other ESRD patients. In order to define if there are certain differences in the clinical parematers including bone metabolism, such as bone mineral density (BMD), serum iPTH level and Tc-99m MDP whole body bone scan between diabetic and nondiabetic ESRD, we evaluated 52 patients with ESRD (20 diabetic ESRD and 32 non-diabetic ESRD) beginning first hemodialysis or peritoneal dialysis at the Department of Internal Medicine in Chungnam National University Hospital, from January to December, 1998. The results were as follows : 1. Twenty patients with diabetic ESRD have been suffered from non-insulin dependent diabetes mellius and diabetic nephropathy. The causes of ESRD of 32 non-diabetic ESRD patients were hypertension (56%), chronic glomerular nephritis (26%), chronic interstitial nephritis (3%), and others (15%), respectively. 2. Serum creatinine, albumin, and phosphorus levels of diabetic ESRD patients were significantly lower than those of non-diabetic ESRD patients(all p<0.05), and creatinine clearance was also significantly higher in diabetic ERSD patients than non-diabetic ESRD patients (p<0.05) at the beginning of renal replacement therapy. 3. There was no significant difference in BMD, serum calcium, iPTH, alkaline phosphatase, 24 hours urine protein excretion, hemoglobin, and Tc-99m MDP whole body bone scan score between diabetic and non-diabetic ESRD patients (all p>0.05). 4. On the multivariable linear regression analysis, there was no statistically significant influence of patient's age, presence or absence of diabetes, iPTH, calcium, phosphorus, ALP, albumin, creatinine and ferritin levels on t-score of bone densitometry. In conclusion, we speculate that diabetic ESRD patients begin renal replacement therapy earlier than other ESRD patients although there was no significant difference in bone metabolism parameters, such as iPTH and bone mineral density.

      • 急激 氣壓 및 酸素分壓 變化가 數種動物의 生體에 미치는 影響 : -特히 弊死時까지 耐力에 關하여-

        李康郁,李元暢 건국대학교 1973 學術誌 Vol.15 No.1

        Experimental studies were performed to the bioeffects of rapid decompression and recompression, using several kinds of animals. The results as follows : 1. After recompression these animals were revealed a severe convulsion outcome within 15 sec. Aftar recompression, the average duration of convulsion were 36.7±7.2 min in mice, 34.8±7.1 min in mature rats and 61.5±36.5 min immature rats. 2. After rapid decompression, the average duration of suration of survival time were 4.71±0.64 min in rats, 3.25±1.04 min in mice, 1.47±0.016 min in uroloncha and 1.77±0.19 min in rabbits. After recompression, the average duration of LD-50 were 86.0 min in mice, 87.5 min in mature rats and 112.5 min in immature rats. 3. All of the animals showed prominent lung lesions that were characterized by hemorrage, atelectasis and edema. The blood samples showed hemoconcentration in all animals.

      • SCOPUSKCI등재
      • 姙娠乳牛 血液像에 關한 硏究

        李康郁 건국대학교 1974 學術誌 Vol.18 No.1

        Hemogram of pregnant dairy cow were studied and the results obtained as follow: 1.Number of erythrocyte, hemoglobin concentration and hematocrit value in pregnant dairy cow was unchanged until the two month of pregnancy but highly significant dicrease was found at the four, sixth, eight, and tenth month of gestation. 1 month after delivers showed the normal value. 2.Mean corpuscular hemoglobin, mean corpuscular volume and mean corpuscular hemoglobin concentration of pregnant dairy cow revealed the tendancy of decrease as gestation progress and 1 month after delivery the value was returned to normal, and highly significant decrease was observed at the sixth and eight month, but no difference were observed at the other period of gestation, 1 month postpartum and sterlity dairy cow. 3.Total leucocyte of pregnant dairy cow increased continuously as gestation and 1 month postpartum the values were returned to normal. Highly significant changes were observed in the sixth and eighth month of pregnancy.

      • 韓牛 卵巢의 生物 統計學値 및 卵巢 疾患에 관한 硏究

        李康郁,李元暢,尹快炳 건국대학교 1972 學術誌 Vol.13 No.1

        Korean native cow 2567 slaughtared in abattoir were investigated fur studying the incidence of ovarian disease and biostatistical value of ovaries. The result obtained in the experiment are summarized as follows : 1) The average length of the ovary; 3.63±0.57cm ... right. 3.41±0.71 cm... left, The average width of the ovary; 2.36±0.49cm ... right. 2.02±0.54cm... left, According to the result the right ovary is bigger then the left. 2) The average waight of the ovary: 6.80±2.05g ... right. 5.40±2.69g ... left. According to the result is that the right ovary is heavier than the left by 1.40g Observation on the correlation between the ovary length and the weight was carried out as follows; r=0.568 ... right ovary. r=0.721 ... left ovary. The result shows that the correlation between two is close. 3) The average diameter of the corpus luteum; 1.15±0.43 cm ... right. 1.17±0.39 cm ... left, The average deep of the corpus luteum 1.34±0.06 ... right. 1.87±0.07 ... left. The result shows that the left is more diameter and deep then the right. 4) The average surface area of the ovary; 11.79±0.24 cm ... right. 11.68±0.25cm ... left. The result shows that the right is more wide then the left. 5) The incedence attributed to the ovarian disease was about 5.36% which includes; 3.11% of follicular cyst, 0.39% of lutein cyst, 1.22% of atrophic ovary and 0.36% agenesis of ovary. 6) Among the incidence, ovarian disease on both side occupied 32.35% whereas 41.9% right side, 25.17% left side, 67.64% was observed on any one side. 7) The average size of cystic ovary was 1.5-2.0 cm in diameter and then followed the size of 3.1-4.0 cm. 8) In 136 case 9, or 2.86%, occurred in cattle from 1 to 3 years outage; 21 or,5.46% in four; 54 or, 10.76% in five; 23 or,7.08% in six; 21 Or, 314 of in 7 to 9; and 2 or, 1.9% occurred over 10 years of age.

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