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윤지하 ( Ji Ha Yoon ),정준우 ( Joon Woo Jung ),박은주 ( Eun Joo Park ),김광중 ( Kwang Joong Kim ),김광호 ( Kwang Ho Kim ) 대한피부과학회 2021 大韓皮膚科學會誌 Vol.59 No.1
A 31-year-old Korean man presented with a 6-month history of a painful nodule on his neck. Excisional biopsy was performed for diagnosis and treatment. Histopathological evaluation of the resected specimen revealed well-demarcated vascular proliferation with adipose tissue in the dermis, and the patient was diagnosed with cutaneous angioleiomyoma with fat modulation. To our knowledge, angioleiomyomas most commonly occur on the extremities, and the head and neck are rarely involved. Few cases of cutaneous angioleiomyomas of the neck have been reported in the literature. We report a rare case of cutaneous angioleiomyoma of the neck. (Korean J Dermatol 2021;59(1):61∼63)
신경섬유종증 1형 가족력이 있는 환자에서 발생한 양성 두부 조직구증 1예
정준우 ( Joon Woo Jung ),윤지하 ( Ji Ha Yoon ),박은주 ( Eun Joo Park ),김광중 ( Kwang Joong Kim ),김광호 ( Kwang Ho Kim ) 대한피부과학회 2021 大韓皮膚科學會誌 Vol.59 No.1
Benign cephalic histiocytosis is a rare subtype of non-Langerhans cell histiocytosis of unknown etiology. It usually occurs in infants and children and resolves spontaneously. A 14-month-old infant presented with multiple papules on his face, trunk, as well as upper and lower extremities. Histopathological examination of a biopsy specimen showed diffuse proliferation of histiocytes in the dermis with scattered lymphocytes and eosinophils. Immunohistochemical evaluation showed cells that were immunonegative for S-100 and CD1a but strongly immunopositive for CD68. Benign cephalic histiocytosis usually affects the head and neck areas and rarely spreads to other sites. Some reports in the available literature have described an association between juvenile xanthogranuloma and neurofibromatosis type 1; however, the association, if any, between benign cephalic histiocytosis and neurofibromatosis type 1 is unclear. We report a rare case of benign cephalic histiocytosis in a patient with a family history of neurofibromatosis type 1. (Korean J Dermatol 2021;59(1):58∼60)