Epinephrine 첨가 Lidocaine 에 의한 액와신경차단시 발생한 Potassium 감소에 대한 Propranolol 의 영향

윤재승,이강창,김태요,임홍섭 대한마취과학회 1989 Korean Journal of Anesthesiology Vol.22 No.3

Recently, interest has been increased on the role of catecholamines in extrarenal potassium homeostasis. This study has undertaken to investigate the effects of epinephrine added to lidocaine for axillary block in HR, MAP, ABG, blood sugar and electrolytes (Na+, K+), and the effects of propranolol, β-adrenergic blocker, on the data. The patients admitted to our hospital for operation of upper extremities were divided into three groups. Group I was 10 patients blocked with lidocaine 30 ml. Group II was 14 patients blocked with lidocaine 30 ml with epinephrine 0.3 mg(1:100,000). Group III was 10 patients pretreated with propranolol (10μ/kg) and blocked with lidocaine 30 ml with epinephrine. After block, the results were as follows. 1) MAP decreased in all group and group III decreased more than group I. 2) HR increased all group and group III decreased more than group I. 3) ABG showed hypoventilatory pattern due to sedative effect by diazepam (0.15mg/kg). 4) Blood sugar value was increased in group I and IIshowed increasing tendency in group III, but this tendency was not significant. 5) Blood K+ concentration decreased significantly and the maximal decrease was 0.5 mEq/L in 30 min after block, but there was not significant decrease in group III. This results indicate that clinical dose of epinephrine(1;100,000) decrease blood K+ concentration significantly and propranolol (10μ/kg) pretreatment prevent K+ decreasing effect of epinephrine. In clinical practice, it is suggested that much care must be paid to use of local anesthetics with epinephrine to hypokalemic patients.

마취중 발생한 악성고열

윤재승,송희선 대한마취과학회 1976 Korean Journal of Anesthesiology Vol.9 No.2

Malignant hyperthermia is a well-recognized syndrome of uncertain etiology. The confusing facts are: the variety and different nature of the triggering agents, the variation in time of onset of rigidity and fever coupled with a variation in response to succinylcholine, the lack of family history in some patients, and its occurence in some who have had previously normal general anesthetics. A case is a 23 year old relatively healthy male patient in whom subtotal gastrectomy was performed under N2O-O2-ether and gallamine anesthesia with induction after pentothal sodium and succinylcholine. This was complicated by an abrupt, high rise in body temperature, muscle rigidity, flushing with peripheral cyanosis, disseminated intravascular coagulation and hyperpnea 40 minutes after induction. He died 3 hours after cessation of anesthesia without effective responce to any active antipyretic therapy. The etiologic factors, incidence, clinical feature, prevention, treatment and prognosis of malignant hyperthermia are discussed.

Off-Line Parameter Identification of Permanent Magnet Synchronous Motor Using a Goertzel Algorithm

윤재승,이경구,이준석,이교범 대한전기학회 2015 Journal of Electrical Engineering & Technology Vol.10 No.6

Generally, internal parameters of the motors and generators can be divided to the resistance and inductance components. They can become a cause of the changing internal parameters because they have sensitive characteristics due to external conditions. The changed parameters can generate the outputs which include error values from the speed and current controllers. Also, it can bring the temperature increase and mechanical damage to the system. Therefore, internal parameters of the motors and generators need to obtain their values according to the external conditions because it can prevent the mechanical damage caused by the changed parameters. In this paper, the off-line parameter identification method is verified using the Goertzel algorithm. The motor used in the simulation and experiments is an interior permanent magnet synchronous motor (IPMSM), and the proposed algorithm is verified by the simulation and experimental results.

한반도 겨울철 혹한 발생 기작으로서 동아시아 겨울 몬순 변화

윤재승,정일웅,신상희,변영화,부경온 한국기상학회 2017 한국기상학회 학술대회 논문집 Vol.2017 No.10

마취가 신혈류 및 위기능에 미치는 영향

윤재승 대한마취과학회 1987 Korean Journal of Anesthesiology Vol.20 No.5

Clinical Course and Risk Factors of Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus in Korea

윤재승,임태석,차선아,안유배,송기호,최진아,권진우,지동현,조양경,박용문,고승현 대한당뇨병학회 2016 Diabetes and Metabolism Journal Vol.40 No.6

Background: We investigated clinical course and risk factors for diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (T2DM). Methods: A total of 759 patients with T2DM without DR were included from January 2001 to December 2004. Retinopathy evaluation was performed at least annually by ophthalmologists. The severity of the DR was classified into five categories according to the International Clinical Diabetic Retinopathy Severity Scales. Results: Of the 759 patients, 523 patients (68.9%) completed the follow-up evaluation. During the follow-up period, 235 patients (44.9%) developed DR, and 32 patients (13.6%) progressed to severe nonproliferative DR (NPDR) or proliferative DR (PDR). The mean duration of diabetes at the first diagnosis of mild NPDR, moderate NPDR, and severe NPDR or PDR were 14.8, 16.7, and 17.3 years, respectively. After adjusting multiple confounding factors, the significant risk factors for the incidence of DR risk in patients with T2DM were old age, longer duration of diabetes, higher mean glycosylated hemoglobin (HbA1c), and albuminuria. Even in the patients who had been diagnosed with diabetes for longer than 10 years at baseline, a decrease in HbA1c led to a significant reduction in the risk of developing DR (hazard ratio, 0.73 per 1% HbA1c decrement; 95% confidence interval, 0.58 to 0.91; P=0.005). Conclusion: This prospective cohort study demonstrates that glycemic control, diabetes duration, age, and albuminuria are important risk factors for the development of DR. More aggressive retinal screening for T2DM patients diagnosed with DR should be required in order to not miss rapid progression of DR.

Risk Factors and Adverse Outcomes of Severe Hypoglycemia in Type 2 Diabetes Mellitus

윤재승,고승현 대한당뇨병학회 2016 Diabetes and Metabolism Journal Vol.40 No.6

Hypoglycemia has been considered as a major barrier to achieving the proper glycemic target in type 2 diabetes mellitus patients. In particular, severe hypoglycemia (SH), which is defined as a hypoglycemic episode requiring the assistance of another person to raise the patient’s glucose level, is a serious complication of diabetes because of its possible fatal outcomes. Recently, the recommendations for diabetes care have emphasized a patient-centered approach, considering the individualized patient factors including hypoglycemia. Many studies have been performed which analyzed the risk factors and clinical outcomes for SH. From the studies, researchers recommend that targeting a less stringent glycosylated hemoglobin level and selecting a safer class of drugs for hypoglycemia are appropriate for patients with a high risk of SH. Also, careful clinical attention to prevent hypoglycemia, including intensive education, is necessary to minimize the risk of SH and SH-related fatal outcomes.

Cardiovascular Disease Predicts Severe Hypoglycemia in Patients with Type 2 Diabetes

윤재승,고승현,고선혜,송기호,유기동,윤건호,박용문,안유배 대한당뇨병학회 2015 Diabetes and Metabolism Journal Vol.39 No.6

Background: To investigate whether a history of prior cardiovascular disease (CVD) is associated with severe hypoglycemia (SH) in patients with type 2 diabetes. Methods: We conducted a prospective cohort study from January 2001 to December 2012 with a median follow-up time of 9.5 years (5,814 person-years). Patients aged 25 to 75 years with type 2 diabetes and without chronic kidney disease were enrolled (n=894), and 624 patients completed follow-up. SH was defined as hypoglycemic episodes requiring hospitalization or medical care in an emergency department. We used the Cox proportional hazards regression analysis to test associations between SH episodes and potential explanatory variables. Results: Among the 624 participants who completed follow-up, 60 patients (9.6%) had previous CVD. Compared to patients without CVD, patients with previous CVD were older, had a longer duration of diabetes and hypertension, received more insulin, and had more diabetic microvascular complications at baseline. During follow-up, 62 patients (9.9%) experienced at least one SH episode (incidence of 1.33 per 100 patient-years). The development of SH was associated with a history of CVD (hazard ratio, 1.99; 95% confidence interval, 1.07 to 3.72; P=0.031) after adjusting for sex, age, diabetic duration, hypertension, hemoglobin A1c levels, diabetic complications, cardiovascular autonomic neuropathy, and insulin use. Conclusion: A history of CVD was an independent risk factor for the development of SH in patients with type 2 diabetes mellitus. For patients with CVD, modulation of glycemic targets and diabetic education for the prevention of hypoglycemia should be implemented.

1월 한반도 지표기온과 시베리아 고기압 간 관계성 변화에 영향을 주는 AO와 ENSO의 비정상성

윤재승,정일웅,신호정,최준태 한국기상학회 2019 한국기상학회 학술대회 논문집 Vol.2019 No.10

우리는 Fun하고 뻔뻔하게 대화한다

윤재승 한국엔터테인먼트산업연구원 2006 ceri 엔터테인먼트연구 Vol.5 No.-