파이란

유정현 한국예술종합학교 영상원 영상이론과 2002 영상이론 Vol.- No.1

다비증증후균의 산전초음파 소견

유정현,서정수,이영호 대한초음파의학회 2004 ULTRASONOGRAPHY Vol.23 No.3

목적 : 산전초음파검사를 통해 경험한 6예의 다비증증후군의 소견을 보고하고자 한다. 재태기간은 18주4일부터 38주까지였고 평균 27주5일 이었다. II군 산전초음파검사를 시행하여 복합심장기형 및 다비증의 소견을 보여 다비증증후군으로 의심된 6예에서,산전초음파소견을 후향적으로 관찰하여 부검 및 산후 추적결과와 비교하였다. 결과 : 산전초음파검사에서 다비증이 발견된 예는 5예이었다. 6예 전 예에서 심혈관계기형이 관찰실흔적 또는 심한 승모판폐쇄증 소견과 동반된 양대혈관우심실기시 2예, 심실 및 심방결손증이 각각 1예에서 관찰되었다. 대정맥단락 및 기정맥연결은 3예에서 관찰되었다. 서맥 2예, 방실해리 1예의 리듬이상 소견이 동반되었다. 복강내 장기위치 이상소견은 전 예에서 관찰되었고, 고에코 소장, 신우확장, 마제신, 후경부의 낭성히그로마의 이상 소견이 동반되었예는 부검을 시행하지 않았다. 1예는 분만하여 심장수술 후 생존하였고, 1예는 추적관찰 되지 않았다. 결론 : 산전초음파검사에서 심장기형을 비롯한 복잡한 태아기형과 함께 다비증을 관찰하면 다비증증후군으로 진단할 수 있다. 또한 다비증증후군에서 흔히 동반되는 대정맥단락 및 기정맥연결을 진단하는데 흉곽후방의 특징적인“double vessel sign”을 관찰함으로써 도움이 될 수있다. PURPOSE : We report 6 cases of polysplenic syndrome diagnosed on prenatal sonography. MATERIALS and METHODS : The mean menstrual age at the time of presentation was 275 weeks (range 184 to 38 weeks). All cases were examined using level-II prenatal sonography. The sonographic findings of polysplenic syndrome were retrograde analyzed and compared to the autopsy or postnatal findings. RESULTS : Polysplenia was detected in 5 cases on the prenatal sonography. Associated cardiovascular anomalies were detected in all 6 cases, all of which had more than one anomaly, namely complete atrioventricular septal defect in two cases, double outlet right ventricle combined with rudimentary LV or mitral atresia in two cases and VSD and ASD in one case each. There were three cases of interrupted IVC with azygous continuation of the posterior thorax. Bradycardia was observed in 2 cases, one of which showed AV dissociation of rhythm. Visceral abnormalities were present in all cases and there were combined anomalies such as echogenic bowel, pelviectasia, horseshoe kidney, and posterior neck cystic hygroma and fetal hydrops. Four cases terminated pregnancy. The autopsy results of 2 cases were comparable to those of the prenatal sonography, however autopsies were not performed in 2 cases. One fetus near term was delivered and the baby subsequently underwent heart surgery and was still alive at the last follow-up. The remaining one case was lost to follow-up. CONCLUSION : If multiple fetal anomalies, including complex heart disease and polysplenia, are detected in the prenatal sonography, a diagnosis of polysplenic syndrome can be made. IVC interruption with azygous continuation can also be helpful in the ddiagnosis of polysplenic syndrome, and this can be observed by detecting the double vessel of the posterior thorax.

유방질환의 유방촬영술에 관한 연구

유정현,이정식 梨花女子大學校 醫科大學 醫科學硏究所 1995 EMJ (Ewha medical journal) Vol.18 No.1

There are variable radiological method for breast disease including mammography, breast ultrasound, thermography, CT-mammography and MRI. Among these, mammography is the oldest and the gold standard for diagnosis of breast disease. In mammography, the primary consideration is the demonstration of the absence or presence of the breast lesion and if present, the benignity of malignancy of the lesion. The authors analyzed the mammographic findings in 145 cases pathologically proven cases of various breast disease. The results were as follows: 1) The most prevalent age group of benign lesion was 3rd-4th decade with frequency of 65.3% and that of malignant lesion was 4th-5th decade with frequency of 66.6%. 2) The most frequent site of breast lesion was upper outer quadrant in benignity and malignancy. 3) Pathologic type of breast malignancy was all of ductal carinoma with various type, and the most common benignity is breast tumor(57.8%) and followed fibrocystic disease(27.3%). 4) The detection of abnormal findings of malignant lesion was 87.5% including mass lesion(75%) and benign lesion was 80.1% including mass lesion(54.5%). Conclusively, the authours suggest that mammography is very useful method for the detection & diagnosis of breast disease.

도플러 초음파를 이용한 미숙아 초자체유리양막질환의 뇌혈역학변화

유정현,김경희 梨花女子大學校 醫科大學 醫科學硏究所 1999 EMJ (Ewha medical journal) Vol.22 No.2

Objectives : To access the changes of cerebral blood flow velocity according to the time after surfactant administration, we prospectively studied in the Hyaline Membrane Disease using Doppler ultrasonography. Materiala and Method : The patients were 26 infants. The mean gestational age was 3l^4wks (range, 18^4 to 38wk). The ratio of male : female was 16 : 10, mean weight was 1.76±0.88Kg, Apgar score at 5min was 6.9, and type of delivery was C-section : vaginal delivery 19 : 4. Before and after, 10, 30min, 1, 6, l2hr, 1, 3, 5, 7days after surfactant administration, peak systolic and end-diastolic flow velocity(PSFV, EDFV) were estimated by Doppler method measuring MCA flow velocity. The Resistive index was calculated according to the mathematics. For the evaluation of the clinical status, systolic and diastolic systemic BP, PaO_2, PaCO_2, FiO_2, pH, and respiratory rate(RR) were checked. Results : The cerebral blood flow velocity showed initial increase of PSFV just after synthetic surfactant administration, and the increased PSFV continued until the 30 minites and then decreased. PSFV returns to initial level at 6hr, and then increased again. The changes of EDFV was not significant. The changes of RI & PI were no significant changes. The effects of surfactant to the systemic BP had no significance. The changes of PaCO_2 and Pa0_2 were not significant. FiO_2 showed steady improvement. Initial tachypnea and acidosis progressively improved without clinical significance. Conclusion : The administration of Surfactant in the HMD patients results in transient increase of cerebral blood flow velocity.

Gadolinium-Enhanced 3D Fast Imaging Steady-State Procession(FISP) MR Venography in the Deep Vein Thrombosis of Low Extremities

유정현,서정수 이화여자대학교 의과대학 2004 EMJ (Ewha medical journal) Vol.27 No.1

연구목적: 하지정맥의 심부혈전 진단에 조영증강 자기공명정맥촬영술을 사용하고, 도플러초음파검사와 비교하여 진단적 가치의 우수성을 나타내고자 한다. 대상 및 방법: 도플러초음파검사상 심부정맥혈전이 의심된 30명의 환자에서 가돌리늄 조영증강 MR 하지정맥술을 시행하였다. MR기법은 삼차원 fast image steady-state procession (FISP) 을 사용하였다. 심부정맥혈전의 진단은 조영증강된 혈관내의 신호강도결핍을 보이는 경우로 하였다. 해부학적 혈관의 분포에 따라 혈관들은 각각 절편(segment)에 따라 외장골정맥, 총대퇴정맥, 표재대퇴정맥, 심부대퇴정맥, 슬와정맥, 전경골정맥, 후경골정맥, 비골정맥, 발목정맥으로 분류하였다. 도플러초음파결과와 비교하여 각각에 대한 통계적 유의성검증을 하였다. 결과: 조영증강 자기공영 정맥조영술은 정상적으로 조영증강되는 혈관과 대조되는 신호강도결핍의 심부정맥혈전을 잘 나타내었다. 30명환자의 40예의 하지에서 각각의 절편에 따라 400절편으로 분류하였을때, 심부정맥혈전은 111절편(27.75%)에서 관찰되었고 도플러초음파상에서는 77(19.25%)에서 관찰되었다. 이중 75절편(17.75%)에서 자기공명영상과 도플러초음파 검사에서 모두 혈전을 나타내었다. Mc-Nemar's chi-squere검사상 자기공명정맥조영술이 도플러초음파 검사에 비해 통계적으로 유의성이 있게 우수함을 나타내었다(Table 1. x²=25.13, p=0.001). 심부혈전의 위치는 표재성대퇴정맥이 가장 많았고, 총대퇴정맥, 슬와정맥, 후경정맥의 순이었다. 자기공명정맥조영술은 외장골정맥, 발목정맥을 관찰하는데 도플러초음파보다 우수하였고, McNemar's Chi-squere 검사상 외장골정맥(x²=8.00, p<0.005), 발목정맥(x²=5.00, p<0.05), 후경정맥(x²=4.00, p<0.05)에서 통계적 유의성을 나타내었다(p<0.05) (Table 2). 결론: 조영증강 자기공명정맥술은 하지정맥 심부정맥혈전의 진단에서 도플러초음파검사보다 통계적으로 유의하게 우수하였다. 특히, 혈전의 공반강 침범과 발목정맥 및 심부calf 정맥의 혈전진단은 통계적으로 유의하게 우수하였다.

그린리모델링 사업 활성화를 위한 민간 이자지원사업 개선연구

유정현,이종건,김봉주,방선규 대한건축학회 2019 大韓建築學會論文集 : 構造系 Vol.35 No.6

The purpose of this study is to derive priority improvement items through business expansion and efficient implementation for greenremodeling business operator in order to enhance the activating of green remodeling business in a long-term perspective. For this purpose,survey of 128 business operator respondent is conducted based on 13 items. Also, priority improvements items were derived based on theresults of the survey by using IPA(Importance Performance Analysis) techniques. As a result, In order to revitalize the green remodeling, itis necessary to induce market participation motivation through monetary profit. Additionally, The management of green remodeling businessoperator and the opinions of owners should be reviewed. In the future, the items that reflect the views of business operator and owners willbe investigated and further research on improvements for expanding green remodeling ‘interest subsidies on existing private buildings will beconducted. 본 연구는 그린리모델링 사업 활성화 및 시장확대를 위한 정부정책 개선사항을 도출하는 것을 목적으로 하고 있다. 이를 위하여 투입, 과정, 결과 및 환류로 구분된 13개 설문을 작성하고 128개 그린리모델링 사업자에 대한 설문을 실시하였다. 설문결과를 바탕으로하는  IPA 결과, 우선적으로 개선이 필요한 항목으로는 이자지원비율 상향 등의 기존 금융혜택 확대 및 세분화, 데이터 정비와 백서 발간 등의 객관적 자료 정비, 관련 기초데이터 및 근거자료의 제공 등이 장기적 측면에서 그린리모델링 사업활성화에 일조할 수 있을 것으로 분석되었다.

매미나방(Lymantria dispar)의 혈림프 exo-β-N-acetylglucosaminidase 2의 정제와 특성

유정현,윤치영,여성문 檀國大學校 基礎科學硏究所 1995 論文集 Vol.6 No.-

매미나방(Lymantria dispar)의 혈림프 exo-$\beta$-N-acetylglucosaminidase 2의 정제와 특성

유정현,윤치영,여성문 한국곤충학회 1994 Entomological Research Vol.24 No.1

매미나방 (Lymantria dispar)에서 4종의 $eta$-N-acetylglucosaminidase를 확인하였으며 이 중 exo-$\beta$-N-acetylglucosaminidase 2(E2)를 column chromatography에 의해 분리, 정제하였다. 분자량은 27Kda, pI는 5.75, $ho$-nitrophenyl-N-acetyl-$\beta$-D-glucosamine에 대한 Km 값은 2.5$\times$$10^{-3}$M이었다. 또한 최적반응 pH는 5.5. 최적반응 온도는 7$0^{\circ}C$이었으며, 7$0^{\circ}C$까지 열안정성을 나타내었으나 그 이후 급격히 활성이 소실되었다. 정제된 효소는 $Mg^{2+}$, $Mn^{2+}$, $Ca^{2+}$, $K^{+}$ 등에 의해 활성이 증가되었으며 반면에 H $g^{2+}$, C $u^{2+}$, F $e^{2+}$, F $e^{3+}$ 등에 의해 활성이 억제되었다.다. Four isozymes of $\beta$-N-acetylglucosaminidase were found in gypsy moth Lympantria dispar. Of these isozymes exo-$\beta$-N-acetylglucosaminidase 2 (E2) was isolated and purified by different types chromatography E2 had a molecular weight of 27 Kda, an isoelectric point of 5.75 and a Km value of 2.5$\times$10$^{-3}$ M. The optimum pH and temperature of the enzyme were pH 5.5 and 7$0^{\circ}C$, respectively, and maintained its normal activity until 7$0^{\circ}C$. E2 was activated by $Mg^{2+}$, M $n^{2+}$, $Ca^{2+}$ and $K^{+}$, and inhibited by H $g^{2+}$, C $u^{2+}$, F $e^{2+}$, F $e^{3+}$./.+}$</TEX>./.

배변증상이 있는 환자에서 비디오 촬영을 이용한 배변조영술

유정현,김광호 梨花女子大學校 醫科大學 醫科學硏究所 2001 EMJ (Ewha medical journal) Vol.24 No.1

Purpose : While some information about colonic function may be obtained from fluoroscopic assessment, detailed depiction of function of the rectum and anal canal during defecation is not possible with conventional technique. Defecography is a useful technique of examining the rectum and canal in which the patient is studied while sitting down and video recordings could be obtained during the procedure. To evaluate the clinical usefulness of defecography in patients with anorectal dysfunction, defecographic examinations were retrogradely reviewed. Materials and Methods : Thirty symptomatic patients performed defecography. The ratio of men : women was 9 : 21, and the age was 8 to 86 years(mean, 36year). Presenting symptoms included a sensation of rectal blockage during straining, rectal prolapse through the anus, anal pain, etc.. While the patient was in the left decubitus position, 250㎖ of a thick barium past was injected into the rectum. The patient was then seated a toilet chair mounted on the footplate of a remote-control stand. And lateral images and video recording centered over the rectum and true pelvis obtained over a period of several minutes, both at rest and during and sqeezing and straining. The defecographaic results were analyzed for the anorectal angle and perineal descent at rest, sqeezing and during straining. Change of rectal configuration and canal width during staining were reviewed. Results : Defecation was normal in 5 patients(16.6%). Rectocele was seen in 17case(56.6%). Rectal proplase with or without intususception was 11 case(36.3%), 3 cases(10%) of sigmoidcele, and 2 cases(6.6%) of dynsfunction of puborectalis. There was a 1 case(3.3%) of rectal polyp. Seven cases(23%) show combined findings : 2 cases with rectocele, rectal intussusception and sigmoidcele, 4 cases with rectocele, rectal intussusecption and rectal prolapse, rectocele and dynsfunction of puborectalis in 1 case. The measurement of anorectal angel was 65°-125°(mean, 104°) in resting state, 57°-90°(mean, 63°) in sqezzing, and 78°-115°(mean, 103°) in straining state. Conclusion : Defecography with video recording is a useful study in assessment and diagnosis of various discase causing anorectal dysfunciton. However, the measurement of anorectal angle was wide range without statistical significance.

복부 전산화단층 촬영상 조영 증강 전후의 전이성 간암 크기에 관한 비교연구

유정현,서정수,이정식 梨花女子大學校 醫科大學 醫科學硏究所 2001 EMJ (Ewha medical journal) Vol.24 No.3

Objectives : To investigate whether measurements of hepatic metastases before contrast administration are different from measuments after contrast administration. And to gain more effective follow up method by analyzing the difference of contrast between pre- and postcontrast scans. Materials and Methods : Thirty patients with herpatic metastases were underwent conventional CT. Continuous 10㎜ thick slices were obtained from liver dome to pelvic inlet, then the patients received Ⅳ injection of contrast material, and same method as precontrast CT scan was performed. Additional 5㎜ thin slice scan was obtained in case of need. Three radiologists performed independent bidimensional measurements of the randomly selected lesion on both pre- and postcontrast images at the same level and analyzed the difference of the size and contrast. Results : The size of hepatic metastases were measured as smaller on postcontrast images ; average 41.4±43.5㎠ on precontrast scan & 35.2±37.5㎠ on postcontrast scan. There was significant difference by paired t-test(p<0.02). 24 of 30 cases(80%) showed better conspicuity on postcontrast images, 5(16.7%), on precontrast images and 1(3.3%) showed similiar conspicuity on both pre- and postcontrast images. The contrast of hepatic metastases was significantly higher on postcontrast scan by chi-square test(p<0.01). Conclusion : Hepatic metastases are significantly smaller on postcontrast images. The contrast between metastatic lesion & liver parenchyme was better on postcontrast scan. Therefore, serial assessment of hepatic metastases size by CT should not be compared mixed pre- and postcontrast image. And postcontrast scan is more effective method than precontrast for follow up of hepatic metastasis.