활동혈압측정에 의한 강압제의 휴약결정

유원상,정태기,김형곤,정성광,최석구 인제대학교 1994 仁濟醫學 Vol.15 No.2

활동 혈압 측정(Ambulatory blood pressure monitoring)의 여러 지표들이 휴약기간에 미치는 영향을 검토하고 그 지표들의 예측성을 평가해보았다. Eighteen patients with essential hypertension were selected to withdraw antihypertensive drug after checking the ambulatory blood pressure monitoring and analysed for variables to pull out some useful clinical indices. The following result were obtained. 1.The shorter the time for the normalization of blood pressure after drug treatment, the longer the duration of drug withdrawal. 2.Pre-withdrawal ambulatory blood pressure monitoring revealed the lower the diastolic blood prssure, mean blood pressure, nightsystolic blood pressure, % of elevated blood pressure, the longer the duration of withdrawal. 3.Cardiomegaly and left ventricular hypertropy and abnormal fundi finding correlated with longer duration of withdrawal. In conclusion, if ambulatory blood pressure mornitoring done earlier than 6 months of normalization, more than 8 months' withdrawal were possible if the criteria of less than 5% of systolic blood pressure elevation and 10% of diastolic blood pressure elevation were strictly observed.

비전형적인 증상을 주소로 내원한 그레이브스병 환자 2예

유원상,정현경 대한갑상선학회 2016 International Journal of Thyroidology Vol.9 No.2

We describe here two Graves’ patients who have presented with atypical symptoms. Interestingly, both of them had symptoms related to imbalance of body fluid homeostasis. Chief complaint of a 35-year-old woman (case 1) was the ipsilateral edema of upper body. A 33-year-old man (case 2) who had severe polyuria has referred from urology department with impression of diabetes insipidus. Both of them denied any typical symptoms of Graves’ disease at presentation. These rare extrathyroid manifestations of Graves’ disease were completely subsided after antithyroid drug treatment. We introduce their clinical courses and possible pathophysiological mechanisms of the atypical symptoms of Graves’ disease.

When and Why Does a Firm Choose a Certain Type of Internet Channel?

유원상 한국상품학회 2006 商品學硏究 Vol.24 No.2

When and Why Does a Firm Choose a Certain Type of Internet Channel?YOO, Weon-Sang*This study explores the choice of Internet channels in the trucking industry. Two of the main Internet channels are considered: electronic transportation exchanges and company Websites. Six case studies are conducted in order to identify the key factors that influence a firm’s choice concerning the adoption of Internet channels. Based on these case studies, we generate a set of testable propositions that can be used as a foundation for future theoretical and empirical research. The case analyses highlight five main factors that influence the adoption of the Internet channels: size of the firm, percentage of business on the ongoing relationships, degree of fragmentation of the industry, transaction size, and size of the network.

急性期 腦경색의 治療

유원상 한국의학사 1993 診斷과治療 Vol.13 No.4

Subclinical Hypothyroidism: Prevalence, Health Impact, and Treatment Landscape

유원상,정현경 대한내분비학회 2021 Endocrinology and metabolism Vol.36 No.3

Subclinical hypothyroidism (sHypo) is defined as normal serum free thyroid hormone levels coexisting with elevated serum thyroidstimulating hormone (TSH) levels. sHypo is a common condition observed in clinical practice with several unique features. Its diagnosis should be based on an understanding of geographic and demographic differences in biochemical criteria versus a global reference range for TSH that is based on the 95% confidence interval of a healthy population. During the differential diagnosis, it is important to remember that a considerable proportion of sHypo cases are transient and reversible in nature; the focus is better placed on persistent or progressive forms, which mainly result from chronic autoimmune thyroiditis. Despite significant evidence documenting the health impacts of sHypo, the effects of levothyroxine treatment (LT4-Tx) in patients with sHypo remains controversial, especially in patients with grade 1 sHypo and older adults. Existing evidence suggests that it is reasonable to refrain from immediate LT4-Tx in most patients if they are closely monitored, except in women who are pregnant or in progressive cases. Future research is needed to further characterize the risks and benefits of LT4-Tx in different patient cohorts.

우리나라의 강압제 사용 경향 : 최근 10년간 클리닉, 종합병원, 전국소비량의 비교

유원상,양대원,류호준,최석구 대한고혈압학회 1997 대한고혈압학회지 Vol.3 No.1

Recent Advances in Autoimmune Thyroid Diseases

유원상,정현경 대한내분비학회 2016 Endocrinology and metabolism Vol.31 No.3

Autoimmune thyroid disease (AITD) includes hyperthyroid Graves disease, hypothyroid autoimmune thyroiditis, and subtle subclinicalthyroid dysfunctions. AITD is caused by interactions between genetic and environmental predisposing factors and results inautoimmune deterioration. Data on polymorphisms in the AITD susceptibility genes, related environmental factors, and dysregulationof autoimmune processes have accumulated over time. Over the last decade, there has been progress in the clinical field ofAITD with respect to the available diagnostic and therapeutic methods as well as clinical consensus. The updated clinical guidelinesallow practitioners to identify the most reasonable and current approaches for proper management. In this review, we focus on recentadvances in understanding the genetic and environmental pathogenic mechanisms underlying AITD and introduce the updated set ofclinical guidelines for AITD management. We also discuss other aspects of the disease such as management of subclinical thyroiddysfunction, use of levothyroxine plus levotriiodothyronine in the treatment of autoimmune hypothyroidism, risk assessment oflong-standing antithyroid drug therapy in recurrent Graves’ hyperthyroidism, and future research needs.

여덟 가지 시약으로 측정한 혈청 갑상선자극호르몬 결과값 차이: 무증상갑상선기능저하증 진료지침의 임상 적용을 위한 참고구간 비교 연구

유원상,김솔잎,박영주,송상훈,이경훈,이은경,이제훈,이호영,정윤재,정현경,팽진철,한민제,강호철 대한갑상선학회 2023 International Journal of Thyroidology Vol.16 No.2

Background and Objectives: Recent guidelines from the Korean Thyroid Association have proposed a threshold of 6.8 mIU/L for diagnosing subclinical hypothyroidism based on local research findings. However, due to the lack of standardization/harmonization, thyroid-stimulating hormone (TSH) testing yields varying results across different reagent manufacturers. Hence, the use of uniform reference intervals is challenging. We aimed to establish assay-specific Korean reference interval for TSH. Materials and Methods: We performed duplicate measurements on 100 serum samples with varying TSH concentrations (0-23 mIU/L) using eight different TSH reagents including Alinity I TSH (Abbott), Access TSH (Beckman Coulter), Elecsys TSH (Roche), TSH3UL (Siemens), TSH IRMA (Beckman Coulter), TSH1 RIA (Brahms), TSH IRMA TUBE II (Riakey), Turbo TSH IRMA (Izotop). Correlation and simple linear regression analyses were conducted among 8 reagents with Roche as the reference. Results: The correlation coefficient for each reagent was notably high at 0.99. Through regression analysis, TSH values equivalent to the 6.8 mIU/L (Roche) were determined for each reagent as follows: Abbott 5.2 mIU/L, Beckman 6.5 mIU/L, Siemens 6.9 mIU/L, Beckman-Radioimmunoassay 7.4 mIU/L, Brahms 5.7 mIU/L, Riakey 5.3 mIU/L, Izotop 6.0 mIU/L. Conclusion: Given the observed differences in TSH values associated with different reagents, it is imperative to consider these differences when interpreting results within various clinical contexts and adapting them to clinical practice.

단일주파수분석을 이용한 심폐소생술 흉부압박깊이 추정

유원상,강성민,최성욱,U, One Sang,Kang, Seong Min,Choi, Seong Wook 대한의용생체공학회 2017 의공학회지 Vol.38 No.4

During the emergency situation such as cardiac arrest, cardiopulmonary resuscitation(CPR) is the most important treatment to maintain patient's blood circulation. Since the quality of CPR can not be easily measured or evaluated by the eye, an assistive device with an accelerometer can help to assess the pressure depth of CPR. In this study, we propose a single frequency analysis method to reduce the error of the accelerometer by extracting only one frequency component from the Fourier transform process. To verify the effectiveness of the single frequency analysis, acceleration data at CPR conditions were measured at a sampling rate of 50 / sec using a wristband equipped with an acceleration sensor. Then, We compared the existing distance estimation method and the single frequency analysis method using the measured data. The amplitude value proportional to the compression depth was obtained by applying the single frequency analysis method.

Estimation of Elastic and Osmotic Drug Infuser

유원상,강성민,김동선,이도연,최성욱 대한기계학회 2016 대한기계학회 춘추학술대회 Vol.2016 No.4