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경막외강내 스테로이드 투여후 관찰된 혈중 Prolactin 증가와 유즙 분비
원석규(Seok Kyu Won),전용석(Yong Suk Chun),석민호( 대한통증학회 1998 The Korean Journal of Pain Vol.11 No.1
Epidural steroid injection have become one of the most frequently applied conservative option for the management of acute and chronic back pain. As the indications for epidural steroid injections increase so do the adverse responses associated with this procedure. This study reports the succession of 3 patients who developed galactorrhea and hyperprolactinemia after recieving an epidural steroid injection for lumbar radiculopathy and low back pain. Serum prolactin level was elevated in accordance with epidural injection of corticosteroid. We measured the serum prolactin level by immunoradiometric assay method and peak serum prolactin level at above 500, 144.2, 150.3 ng/ml respectively. Also we found the serum prolactin level decreased to nonnal values 3 wks after corticosteroid injection. Galactorrhra ceased in advance of decrease of serum prolactin level. That Hyperprolactinemia and galactorrhea can occur following epidural steroid injection, requires a much larger prospective investigation.
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전용석(Yong Suk Chun),원석규(Seok Kyu Won),이명의( 대한통증학회 1998 The Korean Journal of Pain Vol.11 No.1
The presence of an enlarged transverse process on one or both sides of the last lumbar vertebra is a common congenital anomaly of the lumbar vertebra. It is thought to be a genetic or developmental anatomical variant. The first reported assimilation of the fifth lumbar vertebra into the sacrum associated with low back pain was in 1917 by Bertolotti. However, clinical significance of lumbosacral transitional vertebra has not been fully considered due to lack of scientific investigations dealing with it. We experienced a case of symptomatic lumbosacral transitional vertebra during management of low back pain. Low back pain was relieved after infiltration of local anesthetics and steroid into the false joint of lumbosacral transitional vertebra. This result may possibly indicate a significant correlation between low back pain and lumbosacral transitional vertebra.
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