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오충환 한국산업경영시스템학회 1978 공업경영논총 Vol.1 No.1
The purpose of this study is to search for an efficient application method in solving delay-phenomenon problems which influence upon total production cost through case study. The method of this study is an experimental study based on cutting time data in lead cutting operations from "Lead Cutting Machine (Stripper)" and its service rate data from a large electronic products company which utilizes conveyor line system for the products "Car Stereo" The procedure of this experimental study is as follows; 1) Using loading(Man-Hour) analysis technique j,1 order to analyse and evaluate Production capacity, efficiency, operation and idle rate assembly charge, waiting and service cost -when its are controlled by stripper operator(server) 2) Establishing adequate waiting time model of finite population caused by the interference of 4 stripper machine which is drawn from mathematical statistics testing, that is, goodness of fit test in the waiting and service rate and to search for optimal solution by utilizing the above mentioned model The experimental result was that amount to 8,546,618won Per year was brought down, that is, by optimum point, it shows a decrease as compared with Present point. The major limitation of this experimental study is that the Queue in the Finite Population, so to speak. it comes from the interference of 4 stripper machine dealt with this case were limited only on the Car Stereo conveyor line. Further study of application of this application method to the areas such as material handling, personnel management marketing and transportation management is strong1y recommended.trong1y recommended.
Ouabain이 음경해면체평활근에 미치는 영향에 관한 실험적 연구
오충환,김세철 중앙대학교 의과대학 의과학연구소 1992 中央醫大誌 Vol.17 No.3
The effect of ouabain on smooth muscle of the corpus cavernosum itself and its effect on the action of adrenergic, cholinergic or non-adrenergic non-cholinergic neurotransmitters were observed in vivo using dogs as experimental animals and in vitro using isoloated corpus cavernosal strips from rabbit penis. A 21 gauge needle was placed into the cavernous space of the anethetized dog, and intracorporeal pressure(ICP) was measured; 1) before stimulation of the cavernous nerve(NS), 2) during NS and 3) during NS following intracorporeat injection of ouabain. The corpus cavernosal strip was suspended in an organ both containing 20ml of Krebs-bicarbonate solution main-tained at 37 The Krebs-bicarbonate solution was aerated with 95% oxygen and 5% carbon dioxide. One end of the cavernosal strip was fixed at the bottom of the bath and the other end connected to the force displacement transducer. When the stable tension level of the strip reached, drugs were added to the organ bath and the change of contractility of the strip was recorded on a polygraph. The resist were obtained as follows; 1. ICP before and during NS were 9.806.14mmHg(Mean±S.D.) and 107.80±15.76mmHg. ICP during NS following intracorporeal injection of ouabain was 37.00±12.39mmHg at 10 minutes after injection of ouabain 34.00±1.58mmHg at 50 minutes, 28.80±12.15 mmHg at 90 minutes and 28.40±10.55 mmHg at 130 minutes. There was a significal drop of ICP following intracorporeal injection of ouabain(p<0.01) but a significant change of ICP with the time elapsed after obtain injection was not found. 2. Ouabain (1×10^7M) increased the contractility of the isolated cavernosal strip from rabbit. In the pretreated state with tetrodotoxin(5×10^7M), contraction of the strip was induced by ouabain, but neither relaxation nor contraction occurred by additional nerve stimulation. So, ouabain might contribute to the contraction of cavernosal strip not by neuronal effect but by direct action on the smooth muscle. 3. 2-chloro-adenosine and Vasoactive Intestinal Polypepeide(VIP) showed a relaxing effect on the cavernosal strip but acetylcholine had both contraction and relaxing effect. Ouabain partly inhibited the relaxing effect of these neurotransmitter. Therefore, it is concluded that ouabain directly acts on the smooth muscle of the corpus cavernosum and contracts it. However, it seems that the contraction effect of ouabain is less stronger than the relaxing effect of the adenosine, VIP and acetylcholine.