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망막분지정맥폐쇄에서 황반중심부의 후유리체박리가 황반부종에 미치는 영향
김성우,오인경,오재령,허걸,Seong Woo Kim,In Kyung Oh,Jae Ryung Oh,Kuhl Huh 대한안과학회 2006 대한안과학회지 Vol.47 No.3
Purpose: To quantitatively compare the role of posterior vitreous detachment in macular edema associated with branch retinal vein occlusion (BRVO) using OCT. Methods: A retrospective study of 36 eyes with BRVO-associated macular edema was carried out from November 2003 to February 2005. There was posterior vitreous detachment (PVD) in 23 eyes [PVD (+) group], and vitreoretinal attachment on the fovea in 31 eyes [PVD (-) group]. PVD was detected with an indirect ophthalmoscope or 90D lens. The foveal thicknesses of the two groups were measured and compared. Results: The mean foveal thicknesses of the PVD (-) and PVD (+) groups were 398.0±217.2 ?m and 233.6±80.6 ?m, respectively (p=0.000, Mann-Whitney test). The mean BCVA (log MAR) was 0.77±0.52 in the PVD (-) group and 0.40±0.37 in the PVD (+) group (p=0.002, Mann-Whitney test). Conclusions: The extent of macular edema associated with BRVO was significantly less in the PVD(+) group and BCVA was significantly better in the PVD (+) group as well.
양선모,오인경,오재령,허걸,Sun Mo Yang,In Kyung Oh,Jae Ryung Oh,Kuhl Huh 대한안과학회 2006 대한안과학회지 Vol.47 No.7
Purpose: To report a case of cancer-associated retinopathy developed in a patient with small cell lung cancer, which is a kind of paraneoplastic syndrome. Methods: A 78-year-old woman presented complaining of decreased visual acuity and visual field that had developed about 15 days previously. She was diagnosed with small cell lung cancer 1.5 years ago and underwent 3 cycles of chemotherapy. At presentation, the best-corrected visual acuity was hand motion in both eyes and there was no afferent pupillary defect. Slit-lamp biomicroscopic examination revealed no specific abnormality in the anterior segment of either eye, and intraocular pressure was normal. Posterior segment examination demonstrated remarkable arteriolar narrowing in both eyes, but there was little doubt about the presence of an optic nerve lesion such as optic disc edema or pallor. Results: Fluorescein angiography and brain magnetic resonance imaging (MRI) revealed no significant abnormalities. However, electroretinograms (ERG) demonstrated marked reduction in the a and b waves. Visual evoked response was delayed for the latency period. She was treated with systemic steroid, after which her visual acuity gradually improved.
유리체절제술과 백내장 동시수술 후 홍채후유착과 연관된 요인들
김성우,김현승,오재령,허걸,Seong-Woo Kim,Hyeon-Seung Kim,Jae-Ryung Oh,Kuhl Huh 대한안과학회 2005 대한안과학회지 Vol.46 No.7
Purpose: Performing simultaneous vitrectomy and cataract procedure has become a widely accepted treatment for cataract patients with vitreoretinal diseases. We evaluated the risk factors of posterior synechia of the iris after such a combined surgery. Methods: We selected the 149 eyes of 149 patients and reviewed the relationship between posterior synechia of the iris and preoperative condition of patients, intraoperative procedures, and postoperative findings. Results: Twenty-six eyes (17.4%) developed posterior synechia; the risk ratio for female patients was 3.382 (95% CI: 1.014-11.277); in patients with uveitis history it was 9.987 (95% CI: 2.329-42.821); in patients with postoperative anterior chamber hyphema it was 17.477 (95% CI: 1.828-167.144); in patients with postoperative anterior chamber fibrin deposition it was 23.52 (95% CI: 2.938-188.299). In cases with silicone-oil tamponade the risk ratio was 8.531 (95% CI: 2.287-31.831) times higher; and in cases with C3F6 gas tamponade it was 15.786 (95% CI: 3.456-72.101) times higher than those with balanced salt solution tamponade. Conclusions: Risk factors of posterior synechia of the iris after a combined vitrectomy and cataract procedure were being female, uveitis history, silicone-oil tamponade, C3F6 gas tamponade, postoperative anterior chamber hyphema, and postoperative anterior chamber fibrin deposition.
당뇨황반부종에서 안구내 트리암시놀론 단독주입과 베바시주맙 병합주입의 단기 효과 비교
장민욱,김성우,오인경,오재령,허걸.Min Wook Chang. M.D.. Seoung Woo Kim. M.D.. In Kyung Oh. M.D.. Jae Ryung Oh. M.D.. Kuhl Huh. M.D.. Ph.D. 대한안과학회 2008 대한안과학회지 Vol.49 No.8
Purpose: To compare the effect of intravitreal triamcinolone injection with and without bevacizumab for diabetic macular edema. Methods: Of 69 patients (69 eyes) diagnosed with diabetic macular edema without any history of other intraocular disease or intraocular operation, 45 eyes (45 patients) were injected with intravitreal triamcinolone (4 mg) and the remaining eyes (24 patients) were injected with triamcinolone (2 mg) and bevacizumab (1.25 mg). The visual acuity and central macular thickness of treated eyes from both groups was measured using OCT, and these measurements were compared between the two groups. Results: There were no statistical differences between the two groups with respect to baseline data. Central macular thickness (CMT) was reduced in both groups, and BCVA improved in both groups. No significant differences were detected in changes in CMT or BCVA between the two groups. Conclusions: Intravitreal injection of triamcinolone had a beneficial effect on DME in terms of CMT reduction and BCVA improvement. Addition of three consecutive intravitreal bevacizumab injections, however, did not show any significant addictive effect during the follow-up period. J Korean Ophthalmol Soc 49(8):1269-1274, 2008
서영우,김균형,강수연,김성우,오재령,김효명,송종석,Young-Woo Suh,Kyun-Hyung Kim,Su-Yeon Kang,Seoung Woo Kim,Jae Ryung Oh,Hyo-Myung Kim,Jong-Suk Song 대한안과학회 2010 대한안과학회지 Vol.51 No.10
Purpose: To develop methods for the objective measurement of ocular fatigue. Methods: Fifteen patients were enrolled in the present study. Subjects performed visual tasks on a computer for one hour. A survey of ocular fatigue was conducted with a questionnaire. Tear break-up time, blinking rate, ocular protection index, conjunctival injection, maximal blinking interval, temperature of the ocular surface, and visual evoked potential were evaluated before and immediately after the task. Surface electromyography of the orbicularis oculi muscle was performed before and during the task. Results: The survey showed increases in subjective ocular fatigue in all subjects. Tear break-up time, ocular protection index and maximal blinking interval decreased, while temperature of the ocular surface increased after the task. Conjunctival injection showed a tendency to increase. Electromyography, and visual evoked potential did not change significantly. Conclusions: In the present study, tear break-up time, ocular protection index, maximal blinking interval, and temperature of the ocular surface changed as ocular fatigue increased. Therefore, these measures can be objectively used for the evaluation of ocular fatigue. J Korean Ophthalmol Soc 2010;51(10):1327-1332
초광각 주사레이저검안경 영상에 나타나는 망막 외 병변의 특성
이보람(Bo Ram Lee),안재문(Jae Moon Ahn),오재령(Jae Ryung Oh) 대한안과학회 2015 대한안과학회지 Vol.56 No.11
목적: 초광각 주사레이저검안경을 이용한 안저 영상에서 생기는 망막 외 병변에 의한 음영의 종류 및 특징을 알아보고자 하였다. 대상과 방법: Optomap 200Tx (Optos PLC, Dunfermline, Scotland, UK)를 이용한 컬러 안저 영상 중 망막 외 병변에 의한 음영을 보이는 139안을 대상으로 후향적으로 분석하였다. 망막 외의 전안부 또는 유리체의 병변에 의하여 발생하는 고반사 또는 저반사의 음영을 망막 외 병변이라 정의하였다. 녹색 및 적색 레이저광 영상과 자가형광안저 영상에서 나타나는 망막 외 병변의 유형을 조사하 고 특징을 분석하였다. 결과: 모든 영상의 망막 외 병변은 망막 외 병변의 원인이 되는 병변 위치에 따라 두 군으로 나누었다. 전안부 망막 외 병변으로는 각막혼탁, 백내장 등이 있었고 후안부 망막 외 병변으로는 성상유리체증, 후유리체박리, 유리체혼탁, 유리체출혈이 있었다. 앞쪽 망막 외 병변은 녹색과 적색 레이저광 모두에서 저반사도로 보이는 경우가 많았다( p -value<0.001). 뒤쪽 망막 외 병변은 녹색에서는 과반 사도로, 적색에서는 저반사도로 보이는 경우가 많았다( p -value<0.001). 결론: 초광각 주사레이저검안경을 이용한 안저 영상에는 망막 외의 다양한 종류의 전안부 및 후안부 병변에 의한 음영이 포함되어 있었다. 이들 음영은 그 기원에 따라 반사도의 차이를 보였다. 이들 특징을 이해하는 것은 안저 영상을 해석하는 데 도움이 될 것이다. Purpose: To evaluate various types and; characteristics of non-retinal lesions associated with ultra-wide field scanning laser ophthalmoscope images. Methods: This retrospective study included 139 eyes of 139 patients with non-retinal lesions observed on color images obtained using Optomap 200Tx (Optos PLC, Dunfermline, Scotland, UK). The non-retinal lesion is a hyperreflective or hyporeflective shadow due to anterior segment of the eye or vitreous except the retina. Types and characteristics of red laser separation, green laser separation and autofluorescence images of non-retinal lesions were evaluated. Results: All non-retinal lesions in images were categorized into 2 groups according to the location of non-retinal lesions. The ante-rior non-retinal lesions group included corneal opacity, cataract and posterior capsular opacity. The posterior non-retinal lesions group included asteroid hyalosis, posterior vitreous detachment, vitreous opacity and vitreous hemorrhage. Anterior non-retinal le-sions were more often hyporeflective in red and green laser separation images (p < 0.001). Posterior non-retinal lesions were more often hyperreflective in green laser separation images and hyporeflective in red laser separation images (p < 0.001). Conclusions: Ultra-wide field scanning laser ophthalmoscope images can frequently have various shadows from anterior or pos-terior lesions of the eye. These shadows show a difference in reflectivity depending on their origins. To understand the difference helps in the interpretation of the fundus images.