간암환자의 토모치료시 Body-fix 사용유무에 따른 유용성 평가

오병천,최태규,김기철,Oh, Byeong-Cheon,Choi, Tae-Gu,Kim, Gi-Chul 대한방사선치료학회 2010 대한방사선치료학회지 Vol.22 No.1

Purpose: In every time radiation therapy set up errors occur because internal anatomical organs move due to breathing and change of patient's position. These errors may affect the change of dose distribution between target area and normal structure. This study investigates the usefulness of body-fix in clinical treatment. Materials and Methods: Among 55~60 aged male patients who has hepatocellular carcinoma in area of liver's couinaud classification, we chose 10 patients and divided two groups by using body-fix or not. When applying body-fix, we maintained a vacuum of 80 mbar pressure by using vacuum pump (Medical intelligence, Germany). Patients had free breathing with supine position. After working to fuse and consist MV-CT (megavoltage computed tomography) with KV-CT (kilovoltage computed tomography) obtained by 5 times treatments, we compared and analyzed set up errors occurred to (Right to Left, RL) of X axis, (Anterioposterio, AP) of Z axis, (Cranicoudal, CC) of Y axis. Results: Average Set up errors through image fusion showed that group A moved $0.3{\pm}1.1\;mm$ (Cranicoudal, CC), $-1.1{\pm}0.7\;mm$ (Right to Left, RL), $-0.2{\pm}0.7\;mm$ (Anterioposterio, AP) and group B moved $0.62{\pm}1.94\;mm$ (Cranicoudal, CC), $-3.62{\pm}1.5\;mm$ (Right to Left, RL), $-0.22{\pm}1.2\;mm$ (Anterioposterio, AP). Deviations of X, Y and Z axis directions by applying body-fix indicated that maximum X axis was 5.5 mm, Y axis was 19.8 mm and Z axis was 3.2 mm. In relation to analysis of error directions, consistency doesn't exist for every patient but by using body-fix showed that the result of stable aspect in spite of changes of everyday's patient position and breathing. Conclusion: Using body-fix for liver cancer patient is considered effectively for tomotherapy. Because deviations between group A and B exist but they were stable and regular.

시신경척수염(Neuromyelitis Optica)이 동반된 전신홍반루푸스 1예

오병천,김금하,최효진,백한주 대한류마티스학회 2007 대한류마티스학회지 Vol.14 No.3

Neuromyelitis optica (NMO) is an idiopathic inflammatory demyelinating disease, characterized by optic neuritis and myelitis. NMO is a very uncommon and serious neurologic manifestation of systemic lupus erythematous (SLE). We report a 28-year-old man with NMO as neuropsychiatric manifestation of SLE. He was diagnosed as lupus nephritis at 16-year-old. He had optic neuritis at three years and seven months ago. Oral prednisolone was tapered off according to the improved eye symptoms. Two months later, he visited rheumatology clinics for urinary disturbance and paresthesia on both feet. A spinal magnetic resonance imaging revealed increased signal intensity in T2-weighted images from second to sixth cervical level and from eleventh to twelfth thoracic level. We diagnosed neuromyelitis optica and treated with intravenous cyclophosphamide therapy monthly for three times. He was discharged without any neurological deficits and has been followed up.

현대독일어의 기본통사구조 기술 수단으로서의 발렌츠이론 및 실제

전병천 한국독어독문학회 1988 獨逸文學 Vol.41 No.1

Seit der Mitte des 20. Jahrhundert wind Begriff und Theminus der Valenz wirklich in der linguiatischen Literatur verwendet worden. Der sprachwissenschaftliche Valenzbegriff hat sich zuna¨chst in zwei Richtungen entwickelt : Valenz im engeren Sinne und Valenz im weiteren Sinne. Jene betrachte die Valenz ala eine Eigenschaft, die in erster Linie dem Verb zukommt. Diese aber ließ Valenz auch bei andern Wortarten beobachten. Unter Yalenz wird die Fa¨higkeit von Subklassen der morphologischen Klassen Verb, Adjektiv und Nomen verstanden, each Zahl und Art bestimmte Erga¨nzungen zu sich zu nehmen. Dabei steht bis fang das Verb im Vordergrund der Urberlegungen, weil es als strukturelles Zentrum des Satzes aufgefaßt werden kann. In der linguistischen Literatur wird Valenz einerseits auf einer logischsemantischen, anderseits aber such einer syntaktischen Ebene lokalsiert. Bei semantischer Valenz handelt es sich um Selektionsbeschra¨nkungen, die auf Kompatibilita¨t der semantischen Merkmale von Lexemen zuru¨ckzufu¨hren sind. Unter syntaktischer Valenz wird die Fa¨higkeit eines Lexems zur Besetzung von Leerstellen in einer bestimmten Zahl und Art verstanden. Wenn man das Verha¨ltnis der beiden Valenzebenen genauer betrachtet, ist es festzuatellen, daß syntaktische Valenzbeziehungen auf einer abstrakten logisch-semantischen Ebene motiviert sind. Zur Beachreibung der Realisierung logisch-semantischen Valenz auf konkreter Ebene ist ein integriertes Valenzmodell empfehlenswert. Bei der Begru¨ndung syntaktischer Valenz spielt die Semantik eine wichtige Rolle. Zwischen dem In halt und der syntaktischen Umgebungsstruktur eines Valenztra¨gers eine Interrelation zu erkennen. Zur praktiacher Sprachanalyse mu¨ssen beide Seiten von Valenzebenen beru¨cksichtigt werden. Aber die Sprachanalyse kann nicht beim Inhalt, sondern bei der Form angesetzt werden, es zur Zeit noch kein eindeutiges Instrumentarium zur exakten Fassung von sprachlichen Inhalten gibt und die morphosyntaktische Struktur die Grundlage fu¨r einzelsprachlich wichtige Satzkonstruktionen abgibt. Erst each einer formbezogenen Analyse ko¨nnen die semantosyntaktischen Betrachtungen in den Beschreibungszusammenhang aufgenommen werden.

N-6-Halo-2-benzothiazolyl-N'-(o, p, m)-chlorophenylurea類의 合成과 그 抗菌力에 關한 硏究

徐丙天 영남대학교 자원문제연구소 1982 資源問題硏究 Vol.1 No.-

Eight kinds of N-6-Halo-2-bensothiagolyl-N'-(o, m, p)-chlorophenyl ureas have been newly synthesized. All of these urea derivatives exhibited weak antibacterial activities on Staphylo-coccus αureus APPC 65389, Sarcina luteα APCC 9341 (Gram positive bacteria) at the concentration of 250-500㎍/㎖ in general. On the other hand, most of these urea derivatives except compound Ⅷ exhibited strong antibacterial activity on Escherichia coli APCC 25922, Shigella flexneri NIH, Salmonella typhi H 901 (Gram negative bacteria) at concentration of 100-250㎍/㎖. Especially, strong antibacterial activity was observed on compounds Ⅱ and Ⅳ.

미국 환경법상 시민소송제도

소병천(Byung Chun So) 중앙법학회 2004 中央法學 Vol.6 No.4

영국의 환경정보공개에 관한 법제 연구

소병천 ( So Byung-chun ) 한국외국어대학교 법학연구소 2011 외법논집 Vol.35 No.2

Access to environmental information is one of basic civil rights; moreover, it plays a role in improving environment protection through the public participation. Most of developed countries in Europe have independent laws and regulation which provide access to environmental information for EC Directives and Aarhus convention. Korean, like the US, does not have an independent law related access to environmental information; however, Korean government has prepared to legislate such laws. This paper explores the UK Environmental Information Regulation 2004 in order to introduces UK experience of those areas. Therefore, this paper review not only UK environmental informational disclosure legal system but also UK experience such as case laws and government guidance law. The Environmental Information Regulations 2004 (EIR) is a UK statutory instrument that provides a statutary right of access to environmental information held by UK public authorities. The regulations came into force on 1 January 2005. According to the regulation, environmental information includes information about air, water, soil, land, flora and fauna, energy, noise, waste and emissions. Environmental Information also includes information about decisions, policies and activities that affect the environment. The coverage of the Environmental Information Regulations is greater than that of the Freedom of Information Act 2000. The Freedom of Information Act sets out a list of the bodies and classes of bodies that are public authorities, the EIR is less prescriptive. There are two institutions for its implementation; the Information Commissioner and the Information Tribunal. The exemptions that public sector authorities can claim under the Regulations are structured somewhat differently as well. In many cases they are narrower in their scope and application. Public authorities have 20 working days from the receipt of a request to provide the information to the requester. When we prepare the legislation of environmental information acts, it is necessary to review not only the law and regulation but also UK's experience such as court's case. Moreover, it is necessary to establish the independent institution which would be appeal body deciding disclosure of environmental information.

통계계산분야의 현재와 미래

김병천 한국통계학회 1991 Journal of the Korean Statistical Society Vol.20 No.-

통계계산, Statistical Computing, 또는 Numerical Computation for Statistics라고 불리우는 통계의 한 분야는 컴퓨터 산업에 의한 제3의 산업혁명이 일고 있는 현대에서 매우 중요한 위치를 차지하고 있음은 두말 할 것도 없다. 특히 통계학이 컴퓨터가 발전하면서 더욱 더 학문적 발전에 박차를 가하고 있다는 것도 의심할 여지가 없다. 통계가 다루는 데이터는 적은 양으로부터 방대한 양을 다루고 있기 때문에 컴퓨터는 필수불가결한 파트너가 되었다. 1980년 초반에 16비트 컴퓨터가 개발되면서, 통계를 처리하는 장소가 전자계산소로부터 사무실로 옮겨 오기 시작했고, 최근에는 70MIPS이상의 속도를 갖고 있는 탁상용 Workstation이 개발되어 통계학자들의 마음을 설레게 하고 있다. 또한 대량의 데이터를 저장할 수 있는 Laser Compact Disk들이 개발되어 통계분야 및 통계계산분야의 발전에 기대가 더 모아지게 되었다. 그러면 컴퓨터가 발전되고 있는데 왜 통계계산분야의 발전이 필요하며, 현재까지 통계계산분야는 어느 단계까지 와 있으며, 미래를 위한 통계계산분야는 어떻게 변화할 것인지를 한국의 실정에 기초를 두고 논해 보고자 한다.

대장항문 용어정리

김병천 대한외과학회 2011 대한외과학회 학술대회 초록집 Vol.2011 No.11

Chrysanthemums morifolium의 유전적 다양성 분석과 표현형질의 평가

인병천,심성철,임진희 한국화훼학회 2015 화훼연구 Vol.23 No.4

Chrysanthemum (Chrysanthemum morifolium) is one of the most popular ornamental species in the world due to the great diversity of flower color and flower head type. There has been increasing demands for various types of chrysanthemums, such as cut flowers, potted plants and bedding plants. In this work, we investigated genetic diversity in 60 commercial chrysanthemum cultivars using simple sequence repeats (SSRs) and examined the relationship between clustering data and the phenotypic characteristics of chrysanthemum flowers. Cluster analysis based on 38 phenotypic traits showed that most of the chrysanthemum cultivars were separated into 8 groups according to flower color and flower head type. Of the 150 SSR primer pairs tested in this study, 62 primers were obtained from previous studies, while 88 primers were designed using the unigene sequences of C. nankingense and the Expressed Sequence Tag (EST) sequences of C. morifolium in the NCBI database. Thirteen SSR primers were selected based on polymorphism and banding patterns in a subset of 8 cultivars and used to amplify the DNA of 60 chrysanthemum cultivars. A cluster analysis based on these 13 SSR markers showed that all 60 chrysanthemum cultivars were divided into six clusters according to their flower color. To determine the relationship between the phylogenetic tree and flower color, multiple regression analysis (MRA) was performed with flower color as the dependent variable and SSR markers as the independent variables. The MRA results revealed a highly significant relationship (r2 = 0.903, P < 0.05) between the flower color and the SSR markers. These results will benefit chrysanthemum research community to develop elite cultivars. 국화(Chrysanthemum morifolium)는 다양한 화색과 화형 때문에 세계에서 가장 인기 있는 관상식물 중 하나로서 절화, 분화 및 화단용 등 다양한 형태의 국화에 대한 요구가 증가하고 있다. 본 연구는 SSR 마커를 이용하여 국화 60 품종에 대한 유전적 유연관계를 조사하고, 군집분석결과와 표현형간의 상관관계를 조사하기 위하여 수행하였다. 표현형질 38개를 이용한 군집분석 결과, 대부분의 국화 품종들이 화형과 화색에 따라 8개의 그룹으로 분류되는 것으로 나타났다. 본 연구에서 사용된 150 개의 SSR 프라이머는 기존연구에서 보고된 62개와 C.nankingense의 unigene 염기서열 및 C. morifolium의EST 염기서열로부터 디자인한 88개로 구성되었다. 국화8품종에 대한 다형성 및 banding pattern 결과를 토대로하여 국화 60 품종의 DNA 증폭에 사용할 13개의 SSR 마커를 최종 선발하였다. SSR 마커를 이용하여 군집분석을 행한 결과, phylogenetic tree에서 국화 60 품종 전부가 화색에 따라서 6개의 그룹으로 분류되는 것을 확인할 수 있었다. Phylogenetic tree와 화색간의 상관관계를 조사하기 위하여 화색을 종속변수, SSR 마커를 독립변수로 설정한 다중회귀분석(MRA)을 행하였다. MRA 결과는 화색과 SSR 마커간에 통계적 유의성이 높은 상관관계(r2 = 0.903, P < 0.05)를 나타냈다. 본 연구결과는 경쟁력 있는 국화 신품종 육종을 위한 데이터로 활용될 수있을 것으로 생각된다.

Internal Transcribed Spacer 1 부위의 염기서열 분석을 통한 피부사상균의 계통발생 및 분류

김병천,김정철,서무규 대한피부과학회 2000 대한피부과학회지 Vol.38 No.9

Background: The species of dermatophytes have been identified and classified by morphological and biochemical characterization as well as by mating experiments. But these techniques are either time consuming or lacking specificity. Recently molecular analysis has been introduced to the field of medical mycology. Objective: We investigated the phylogeny and taxonomy of the dermatophytes using sequence analysis of the ribosomal intemal transcribed spacer 1 (ITS1) region. Methods: 15 species of dermatophytes (6 strains of T. rubrum, 4 strains of T. meetagrophytes subtypes, M. canis, M. gypseum, E. floccosum, T. verrucosum, and T. tonsurans) were cultured on Sabouraud dextrose broth and their DNA was extracted by bead-beating method. Cloning and sequencing of PCR product was done. Results: The size of specific bancls among dermatophytes was 340 bp in ITS1 region. Phylogenetic analysis of sequences reveaied that 6 strains of T. rubrum showed genetically identical patterns in intraspecies, but subtypes of T. mentagrophytes were different. The other dermatophytes showed different patterns in interspecies. The following taxonomy were so closely related: granular form of T. mentagrophytes and T. tonsurans; powdery form, persicolor form and downy form of T. mentagrophytes; and M. gypseum and E. floccosum. Conclusion: The phylogenetic analysis of ITS1 region provided useful information for classification and understanding the evolution of dermatophytes species.