수산용 경구백신의 개발경향 및 산업적 적용

안경진 한국수산과학회 양식분과 2020 한국수산과학회 양식분과 학술대회 Vol.2020 No.7

대한민국의 새로운 정신건강의학과 전공의 수련과정개발

안경진,이승환,박은진,손인기,이재헌,이정석,한상우 대한신경정신의학회 2013 신경정신의학 Vol.52 No.4

As the government has a plan to terminate medical internships and to start the New Resident program, postgraduate medical students should encounter the new residency training program without the internship from 2015. To keep pace with this significant change, the Korean Neuropsychiatry association launched the task force team to manage this problem. The task force team has examined the psychiatry residency training programs from major countries, including England, Japan, Germany, Australia, New Zealand, and the Unites States. In addition, we conducted a survey for teaching psychiatrists and psychiatry residents who just finished the Psychiatry Board Examination in 2013 using a premade questionnaire on the expected problems that might occur if the internship program were abolished, and some significant issues regarding resident rotation schedule to other departments. In this paper, we summarized the results of our examination and survey. Establishment of a new residency training program based on these surveys would be desirable. As the government has a plan to terminate medical internships and to start the New Residentprogram, postgraduate medical students should encounter the new residency training programwithout the internship from 2015. To keep pace with this significant change, the Korean Neuropsychiatryassociation launched the task force team to manage this problem. The task forceteam has examined the psychiatry residency training programs from major countries, includingEngland, Japan, Germany, Australia, New Zealand, and the Unites States. In addition, we conducteda survey for teaching psychiatrists and psychiatry residents who just finished the PsychiatryBoard Examination in 2013 using a premade questionnaire on the expected problems thatmight occur if the internship program were abolished, and some significant issues regarding residentrotation schedule to other departments. In this paper, we summarized the results of our examinationand survey. Establishment of a new residency training program based on these surveyswould be desirable.

`89 내무행정 역점시책 `89 민방위행정 역점시책

안경진 대한지방행정공제회 1989 地方行政 Vol.38 No.424

N/A

Reflections on the Movement for the Legalization of “Death with Dignity as Withdrawal of Futile Life-Sustaining Treatment” in South Korea

안경진,배현아 서울대학교 아시아태평양법연구소 2010 Journal of Korean Law Vol.10 No.1

In this article, we will introduce Korea’s medico-legal cases that are related to the withdrawal of life-sustaining treatment. This paper examines the issue of the legalization of “death with dignity” by investigating Korea’s leading cases on the withdrawal of life-sustaining treatments and the current medical and legal situation in Korea. This paper also examines several preconditions for drafting a bill for such legislation. Considering the complexity of medical circumstances, laws and policies on end-of-life decision-making may not address every possible scenario. Thus, the laws and the policies would have to reflect the differing views of people based on their social status, moral values, religious beliefs, and economic status. Therefore, it should be recognized that a public consensus is necessary for devising successful public policy and guidelines with respect to euthanasia and “death with dignity” in Korea. So proper guidelines and public debates that incorporate the views of the public, the government, and medical and legal professional associations will help create a firmer foundation for making better laws and policies regarding the end of life care issues.

15 years journey of idiopathic pulmonary arterial hypertension with BMPR2 mutation

안경진,장영우,박수정,정욱진 대한고혈압학회 2020 Clinical Hypertension Vol.26 No.1

Pulmonary arterial hypertension (PAH) is known as one of diseases with the worst prognosis. Recently, targeted PAH drugs have been developed and approved for use; therefore, the treatment strategy and goals have changed, and the prognosis has improved over two decades. We reviewed the case of a female who showed the natural disease course of heritable PAH in treatment with the targeted PAH drugs under the Korean Health Insurance policy. At the age of 15, she visited the outpatient clinic for dyspnea on exertion that occurred 3 years ago. At that time, severe pulmonary hypertension was revealed by an echocardiography and there was no evidence of significant shunt lesion or embolism. After 4 years of loss to follow-up, her performance was WHO functional class III and she still suffered from dyspnea. The initial monotherapy using an endothelin receptor antagonist was started in 2008. After 2 years, BMPR 2 mutation was detected. Her clinical symptoms gradually worsened because of poor compliance. To escalate therapy, combination therapy was given, and finally, triple maximal therapy was maintained. The next step is to consider intravenous prostanoids. Various combinations of targeted therapy have been tried, and several trials have been confirmed that improve the prognosis. Initial upfront combination therapy and a more enthusiastic approach make good a better prognosis. In this area, active support of the government insurance policy is indispensable in Korea.

불평등 제시 방식이 북한이탈 청소년들의 학업태도에 미치는 영향

안경진,한인숙,김혜숙 한국사회및성격심리학회 2015 한국심리학회지 사회 및 성격 Vol.29 No.4

The purpose of this research was to investigate the effect of inequality frames on academic engagement of the migrated North Korean adolescents. We also examined whether the perception of injustice or identity threat mediated the effect of inequality frames on attitudes toward academic work. In Study 1 we compared the perceived importance of and motivation for study of the migrated North Korean adolescent students with that of South Korean students through a questionnaire survey. The results demonstrated that the migrated North Korean adolescents indeed perceived lower level of importance of and motivation for academic work than South Korean adolescents. The results of Study 1 also showed that as expected, motivation for study of migrated North Korean students decreased as they perceived a higher level of injustice in educational systems of Korea. On the other hand, importance of study increased as they perceived a higher level of injustice.. In Study 2 we manipulated three types of inequality framing (that is, the present academic inequality between the two groups of students was framed as South Korean students’ advantage vs. as North Korean migrant students’ disadvantage vs. no frame control) and investigated whether the academic engagement of the migrated North Korean students differed in terms of the inequality frames. The results demonstrated that as expected, compared to the inequality frame in terms of North Korean students disadvantage and the control condition, the frame in terms of South Korean advantage made the North Korean students perceive higher level of importance of academic work. In addition, we found the mediation effect of the perception of injustice in educational systems for this framing effect on the perception of the importance of academic work. In the case of motivation for academic work, as expected, compared to the inequality frame in terms of North Korean students disadvantage, the frame in terms of South Korean advantage made the migrated North Korean adolescents tend to report higher academic motivation. However, we did not find the mediation effect of the perception of injustice nor the identity threats on motivation for academic work. We discussed theoretical and practical implications of these findings. 본 연구에서는 북한이탈 청소년들의 학업중요도 지각 및 학업동기를 알아보고 불평등 제시 방식(프레이밍)이 이에 영향을 미치는 지를 검토하고자 하였다. 또한 이러한 불평등 프레이밍 효과가 불공정 지각 혹은 정체성 위협에 의해 매개되는지를 검토하고자 하였다. 이를 위해 연구 1에서는 남한 청소년들과 북한이탈청소년에 대한 조사를 통해 실제로 북한이탈 청소년들이 남한 청소년들보다 낮은 학업동기 및 중요도를 보고함을 확인하였다. 또한 북한이탈 청소년들은 예상대로 교육체제의 불공정성을 높게 지각할수록 낮은 학업동기를 보였으나 다른 한편 예측과는 달리 높은 학업중요도를 지각함을 확인하였다. 연구 2에서는 학업 격차의 원인에 대한 불평등 제시 방식(프레임)을 조작하여 남한유리함 프레임조건에서 북한 불리함 프레임이나 통제조건에서보다 북한이탈 청소년들의 학업중요도 지각 및 동기가 더 높은 지를 검토하였다. 그 결과, 가설과 일치하게, 현재 존재하는 학업격차가 남한 청소년들에게 유리하게 구성된 교육과정 때문으로 제시되었을 때, 북한이탈 청소년들에게 불리하게 구성된 교육과정 때문이라고 제시되었을 때 혹은 불평등이 구체적으로 제시되지 않았을 때보다(통제조건) 더 높은 학업중요도를 지각하는 것을 발견하였다. 또한 이러한 프레이밍 효과는 불공정성 지각에 의해 매개되었다는 결과가 나타났으나. 구체적 방향성은 예측과는 달리 남한유리함 조건에서 다른 조건에서보다 교육체계의 불공정성 지각이 더욱 높아졌고 그에 따라 학업중요도 지각이 더 높아졌기 때문인 것으로 나타났다. 학업동기의 경우, 가설대로 남한 유리함 조건일 때 북한이탈 불리함 조건일 때보다 더 높은 학업동기를 보고하는 경향이 있었다. 그러나 이러한 효과는 불공정성 지각이나 정체성위협에 의해 매개되지 않았다. 이러한 결과들에 대한 이론적․실제적 의미를 논의하였으며 연구의 제한점 및 후속연구에 대해 제안하였다.

광자쌍을 이용한 광검출기의 양자효율 절대측정

안경진 한국광학회 1993 한국광학회지 Vol.4 No.4

자발적매개하향변환과정에서 발생되는 광자쌍을 동시계수하여 광전자증배관의 양자효율을 측정하였다. 표준광원이나 표준광원이나 표준복사계를 필요로하지 않는 이 방법으로 560nm에서 850nm 까지의 파장영역에 대하여 3%의 오차로 양자효율을 측정하였으며, 633 nm에서의 측정치는 교정된 레이저출력계와의 비교에 의하여 얻어진 값과 측정오차 내에서 일치하였다. The quantum efficiencies of photomultiplier tubes were measured by counting the coincidence photon pairs generated in the process of spontaneous parametric down-conversion. They were measured within 3% accuracy over the range of wavelength from 560 to 850 nm without any standard light source or detector. The values for 633 nm correspond to those obtained with a calibrated laser power meter within the measurement error.

Alagille syndrome and a JAG1 mutation: 41 cases of experience at a single center

안경진,윤자경,김기범,권보상,고정민,문진수,배은정,노정일 대한소아청소년과학회 2015 Clinical and Experimental Pediatrics (CEP) Vol.58 No.10

Purpose: Alagille syndrome is a complex hereditary disorder that is associated with cardiac, hepatic, skeletal, ocular, and facial abnormalities. Mutations in the Notch signaling pathway, such as in JAG1 and NOTCH2, play a key role in embryonic development. A cardiac or hepatic presentation is a critical factor for determining the prognosis. Methods: We conducted a retrospective study of 41 patients with Alagille syndrome or a JAG1 mutation between 1983 and 2013. Results: The first presentations were jaundice, murmur, cyanosis, and small bowel obstruction at median age of 1.0 months (range, 0–24 months). The JAG1 mutation was found in 27 of the 28 genetically- tested patients. Cardiovascular anomalies were identified in 36 patients, chronic cholestasis was identified in 34, and liver transplantation was performed in 9. There was no significant correlation between the severity of the liver and cardiac diseases. The most common cardiovascular anomaly was peripheral pulmonary stenosis (83.3%), with 13 patients having significant hemodynamic derangement and 12 undergoing surgical repair. A total bilirubin level of >15 mg/dL with a complex surgical procedure increased the surgical mortality (P=0.022). Eight patients died after a median period of 2.67 years (range, 0.33–15 years). The groups with fetal presentation and with combined severe liver and heart disease had the poorest survival (P<0.001). Conclusion: The group with combined severe liver and heart disease had the poorest survival, and multidisciplinary approach is necessary to improve the outcome.

The 21cm Background from the Cosmic Dark Ages and the Second-generation Star Formation

안경진 한국천문학회 2005 天文學會報 Vol.30 No.2

다양한 고적색편이 별탄생 모형에 따른 우주 재이온화 역사의 변이

안경진 한국천문학회 2019 天文學論叢 Vol.34 No.3

We present a semi-analytical method to calculate the global evolution of the ionized state of the intergalactic medium, on the basis of physically motivated star formation histories in the early universe. This method incorporates not only the conventional scenarios in which the star formation rate is proportional to the growth rate of the halo collapse fraction, but also the more sophisticated scenarios in which the star formation is self-regulated. We show that this variance in the star-formation model strongly impacts the resulting reionization history, which bears a prospect for observational discrimination of these models. We discuss how observations of the anisotropic polarization of the cosmic microwave background and the global 21cm signal from the high-redshift universe, most notably by Planck and EDGES, may probe the history of reionization