고농축 생약 제조기의 설계 및 검증

신준 한국기계기술학회 2022 한국기계기술학회지 Vol.24 No.6

Recently, as interest in safe food and ingredient content has increased, the demand for highly concentrated health functional food that can be manufactured at home is increasing. Accordingly, in this study, we developed a galenic maker that can increase the extraction efficiency of herbal medicine(ginseng) ingredients and shorten the manufacturing time. After verifying the safety of the designed components through structural analysis and thermal flow analysis, the dimensions and shape of the galenic maker were determined. A prototype was produced based on the design process and the performance of the product was verified through extraction efficiency and ingredient analysis.

뉴로-퍼지 기법에 의한 자동차 진단

신준,오재응,Shin, Joon,Oh, Jae-Eung 대한기계학회 1992 대한기계학회논문집 Vol.16 No.10

본 연구에서는 자동차의 발달에 따른 정비 전문가의 상대적인 능력 감퇴를 보 완하고 진단의 정확성을 높일 수 있도록 소음계측에 의한 인공 지능적 뉴로-퍼지 진단 기법을 연구하였다. 이를 위하여 진단결과에 영향을 미치는 많은 작용변수와 다양한 차량상태 등을 고려함으로서 보다 신뢰성 있는 결과를 산출해내기 위한 퍼지(fuzzy) 추론 방식의 판단법을 도입하였으며, 진단이 실패했을 경우나 입력된 데이터가 충분하 지 못할 경우에 시스템 자체의 지식을 확장시켜 나갈 수 있도록 해밍네트(hamming net )에 의한 패턴인식 기법을 적용하였다. 그리고 컴퓨터 시뮬레이션과 자동차를 대상 으로 고장진단 실험을 실시하여 기존의 진단기법과의 비교를 통한 뉴로-퍼지 진단기법 의 효율성과 알고리즘의 타당성을 검증하였다. In the diagnostic process for automobile, Neuro-Fuzzy technique was compared with the conventional diagnostic method for the verification of performance, and proto-type system was developed. For the utilities of the system, 1/3 octave filter(band-pass filter) and A/D converter were used for data acquisition and then data were analyzed using octave band processing and pattern recognition using hamming network algorithm. In order to raise the reliability of the diagnostic results by considering many operating variables and condition of automobile to be diagnosed, fuzzy inference technique was applied in combining several information. The validation of this diagnostic system was examined through computer simulation and experiment, and it showed an acceptable performance for diagnostic process.

NMR Structural Studies on Novel Disintegrin, Saxatilin from Gloydius saxatilis Venom

신준,이동희,홍성유,정광해,김두식,이원태 한국자기공명학회 2007 Journal of the Korean Magnetic Resonance Society Vol.11 No.1

A new disintegrin protein named saxatilin was purified from Korean snake venom (Gloydius saxatilis). Saxatilin is a 73 residue small ploypeptide, which has a primary recognition motif in extracellular matrix, Arg-Gly-Asp (RGD) sequence. Data from inhibition activity assay for the αvβ3 integrin showed that saxatilin showed about 5000-fold higher activity than those of RGD peptides, suggesting that RGD sequence may not be sufficient to induce full cellular function of this site. The solution structures calculated from NMR data were well converged for backbone atoms except RGD loop. The structure revealed that most of tight turns are stabilized by medium range NOE contacts and the RGD motif is located far from the rigid core of the C-terminal domain. The three-dimensional fold and biological function of saxatilin are discussed with those of salmosin, which is a disintegrin protein derived from Agkistrodon halys brevicaudus.

Structure-Function of the TNF Receptor-like Cysteine-rich Domain of Osteoprotegerin

신준,Young-Mee Kim,Song-Zhe Li,임승길,이원태 한국분자세포생물학회 2008 Molecules and cells Vol.25 No.3

Osteoprotegerin (OPG) is a soluble decoy receptor that inhibits osteoclastogenesis and is closely associated with bone resorption processes. We have designed and determined the solution structures of potent OPG analogue peptides, derived from sequences of the cysteine- rich domain of OPG. The inhibitory effects of the peptides on osteoclastogenesis are dose-dependent (10−6M−10−4M), and the activity of the linear peptide at 10−4M is ten-fold higher than that of the cyclic OPG peptide. Both linear and cyclic peptides have a β-turnlike conformation and the cyclic peptide has a rigid conformation, suggesting that structural flexibility is an important factor for receptor binding. Based on structural and biochemical information about RANKL and the OPG peptides, we suggest that complex formation between the peptide and RANKL is mediated by both hydrophobic and hydrogen bonding interactions. These results provide structural insights that should aid in the design of peptidyl-mimetic inhibitors for treating metabolic bone diseases caused by abnormal osteoclast recruitment.

연통내 배기가스 중 이산화탄소 저감장치 개발

신준 한국기계기술학회 2014 한국기계기술학회지 Vol.16 No.4

우루시올이 제거된 생옻 추출물 제조장치

신준,이태연 한국기계기술학회 2017 한국기계기술학회지 Vol.19 No.5

In this study, manufacturing equipments for urushiol free raw rhus verniciflua stem(RRVS) extracts are developed which do not need for drying process and high pressure device. The three layered pressure tank and heating medium oil boiler are designed which are more efficient than the conventional ones, and the safety of the tank is assured by the structural analysis software. Finally, the RRVS extracts are prepared by water extraction technique at 100℃ using the developed equipments. In the physicochemical experiments for the RRVS extracts, an allergen such as urushiol is not detected, whereas the antioxidant such as polyphenol and flavonoid are contained.

카카오프렌즈 캐릭터를 활용한 브랜드 전략에 대한 연구

신준,김승인 사단법인 한국브랜드디자인학회 2020 브랜드디자인학연구 Vol.18 No.1

This study is based on the case analysis based on David Arker's brand identity strategy theory, which is a single target called Kakao Friends. It distinguishes the main structure of the basic identity system and draws the elements that Kakao Friends has. Analyze intrinsic value, such as functions held by emoticons, and the characteristics of images formed in mobile platform to derive key identity structures. It also analyzes the relationship between its parent company, Kakao Talk, to draw a brand essence and to analyze the characteristics of its collaboration and professional character stores. This presents the core of the brand identity, the essence that binds it, and the structure of the extended identity that re-implement it. Since then, he has introduced his relationship with brand recognition and his value proposition and suggested the limitations of the character. According to the analysis, Kakao Friends characters, which have been linked to Kakao Talk's brand essence, had the core value of identity: accessibility, empathy and deficiency. In addition, extended identities were formed around visual and emotional images embodied by the use of emoticons. Extended identity was serving to offer value to consumers by transforming emoticons while maintaining existing core identities. Furthermore, it has led to stores that sell goods exclusively for their own brand characters, focusing on products that are easy to access. In conclusion, we could see that Kakao Friends is similarly controlling the propensity and design of businesses that serve around the core identity of empathy. This could suggest the formation of a strategic brand identity to have in the high value-added industry and the potential and importance of the character to do so. 본 연구는 카카오프렌즈 캐릭터를 데이비드 아커의 브랜드 아이덴티티 전략 이론에 따라 분석한다. 기본적인 아이덴티티 시스템의 구조를 구분해 브랜드 요소를 도출한다. 브랜드 아이덴티티의 핵심, 이를 묶어주는 에센스, 그리고 이를 다시 구현시켜주는 확장 아이덴티티의 구조를 구분한다. 이를 통하여 브랜드 인지도와의 관계와 가치제안을 분석한다. 분석 결과, 카카오톡의 브랜드 에센스인 연결에서 이어져 온 카카오프렌즈 캐릭터가 접근성과 공감 그리고 결핍이라는 아이덴티티의 핵심 가치를 지니고 있었다. 또한 이모티콘 사용으로 인해 구현된 시각적/정서적 이미지를 중심으로 확장 아이덴티티가 형성되어 있었다. 확장 아이덴티티는 기존의 핵심 아이덴티티를 유지한 상태에서 이모티콘을 변형 및 대입함으로써 소비자에게 가치를 제안하는 역할을 하고 있었다. 더 나아가 자사 브랜드 캐릭터 전용 굿즈 매장으로도 이어졌으며 접근성이 용이한 상품을 판매하고 있었다. 결론으로 카카오프렌즈는 공감의 핵심 아이덴티티를 중심으로 서비스와 디자인을 정체성 있게 조절하고 있음을 볼 수 있었다. 그래서 브랜드가 가진 고유한 통일된 이미지가 형성되고 차후 확장되는 사업에도 영향을 끼쳤다. 고부가가치 산업이 가져야 할 브랜드의 정체성 형성과 이를 위한 캐릭터에 대한 가능성과 중요성을 이 논문을 통하여 제시할 수 있었다.

지능진단기법에 의한 원심펌프의 고장진단에 관한 연구

신준,이태연 한국공작기계학회 2003 한국생산제조학회지 Vol.12 No.4

The rotating machineries always generate harmonic frequencies of their own rotating speed, and increment of vibration amplitude affects to the equipments which connected to the vibrational source and causes industrial calamities. The lief cycle of equipments can be extended and damages to the human beings could be prevented by identifying the cause of malfunctions through prediction of the increment of vibration and records of vibrational history. In this study, therefore, diagnostic expert algorithm for the contrifugal pump is developed by integrating fuzzy inference method and signal processing techniques. And the validity of the developed diagnostic system is examined via various computer simulations.

원대 용천요의 요업상황과 동시기 침몰선 출수 용천요자기에 대한 고찰

신준 국립해양문화재연구소 2016 해양문화재 Vol.9 No.-

대학 원격강의 프로그램의 사용성 연구 -Zoom과 Webex Meetings를 중심으로-

신준,김승인 한국디지털정책학회 2020 디지털융복합연구 Vol.18 No.10

This paper is to evaluate the usability of two representative video meeting services currently used by university for research to improve the quality of university remote lecture. questionnaires based on Kano Model were designed and in-depth interviews were conducted to provide qualitative approaches. Screen-sharing functions, the one-dimensional functions was the most important function. and attractive functions had relatively diverse directions. For essential functions, there was a wide gap in quality due to user-specific equipment. The function in which other platforms exist or business-related was not important. Webex reacted negatively to the aging UI, while Zoom responded negatively to the unilateral mute function. In addition, the development direction was presented in five ways as a result of analysis of these results. under Corona-19 situation, I hope this study will lead to continuous research to make stepping stone for remoted educational development. 본 연구는 대학 원격강의의 질을 높이기 위한 연구의 발판이 되도록 현재 사용되는 대표적인 두 개의 화상 미팅서비스의 사용성 평가를 하는 것이다. 기능을 중심으로 분석하기 위해 카노모델(Kano)을 기반으로 한 질문지를 설계하여 반구조적 심층면담을 실시해 정성적인 접근을 꾀하였다. 두 서비스의 1차원적 기능인 화면공유 기능이 중요하게 여겨지고 있었고 매력적인 기능들은 비교적 다양한 방향성을 갖고 있었다. 꼭 있어야 할 기능인 카메라, 마이크의 경우 사용자에 따른 장비로 인해 질의 격차가 컸다. 대체할 타 플랫폼이 존재하는 업로드/다운로드 기능과 교육적 목적과 거리가 있는 예약하기, 전화걸기 기능들은 활용가치가 낮았다. 웹엑스는 전체적인 노후 된 UI가, 줌은 일방적인 음소거 기능이 원치 않는 기능으로 조사되었다. 그리고 이러한 결과를 분석해서 도출한 결론으로 개발 방향성을 다섯 가지로 제시하였다. 코로나-19에 따른 장기적인 교육 운영 방식을 고민해야 하는 상황에서 본 연구가 이러한 화상미팅 서비스가 교육용으로 개발되는 발판이 되도록 지속적인 연구로 이어져야 할 것이다.